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All Journal Jurnal Ilmu Pertanian Indonesia Transmisi Rekayasa Mesin Journal of Mechanical Engineering Science and Technology JPSE (Journal of Physical Science and Engineering) Buletin Ilmiah Sarjana Teknik Elektro Jurnal Karinov Jurnal Abdi Insani Jurnal Pengabdian, Pendidikan dan Teknologi Jurnal Graha Pengabdian Teknomekanik Mechanical Engineering for Society and Industry Automotive Experiences International Journal of Education, Vocational and Social Science
Heru Suryanto
Universitas Negeri Malang
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Physics Social Sciences Transportation Other

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Journal : Jurnal Ilmu Pertanian Indonesia

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Pengaruh Nanovaksin Berbasis Nanopartikel Hybrid Chitosan Terhadap Sel Darah Ikan Kerapu Cantang Yang Diinfeksi VNN Gian Suryanatha Hartawan; Uun Yanuhar; Muhammad Musa; Heru Suryanto; Gunanti Mahasri; Apri Supii; Nico Rahman Caesar
Jurnal Ilmu Pertanian Indonesia Vol. 28 No. 4 (2023): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18343/jipi.28.4.650

Abstract

Cantang grouper (Epinephelus sp.) is a fish with a high economic value and has been widely cultivated. VNN disase, caused by Betanodavirus infection, can lead to mass mortality of cantang grouper. Precautions considered effective in preventing Viral nervous necrosis (VNN) disease include vaccination. This study aimed to determine the effect of administering recombinant Chlorella vulgaris protein nanovaccine based on chitosan hybrid nanoparticles in increasing the immune response of cantang grouper infected with VNN. The study consisted of five treatments: K+ (cantang grouper infected with VNN), K- (healthy cantang grouper), T1 (healthy cantang grouper given 33 µl of nanovaccine and then challenged with VNN), T2 (healthy cantang grouper given 66 µl of nanovaccine and then tested with a VNN challenge), and T3 (healthy cantang grouper given 112 µl of nanovaccine and then tested with a VNN challenge). The parameters observed were haematology, nanovaccine Relative percent survival (RPS), and Survival rate (SR) levels. The study results showed that administering the nanovaccine increased the immune response of the fish, as indicated by an increase in haematology response, RPS, and SR in cantang grouper compared to the treatment without nanovaccine administration. The best dose of nanovaccine in this study is 33 µl. Keywords: fish disease, nanovaccines, virus, C. vulgaris, grouper
Co-Authors Adhitya, Dewa Sukma Trinanda Agung Prabowo Ahmad Atif Fikri Aisyah Larasati Ali, Alamry Amasda, Naufal Rizky Aminnudin, Aminnudin Ananto, Rifqi Ryandi Dwi Andoko Andoko, Andoko Anni Faridah Apri Supii Arbianto, Ferian Rizki Ardianto Prasetiyo Asus Maizar Suryanto H Avita Ayu Permanasari Bili Darnanto Susilo Binoj, Joseph Selvi Daimon Syukri Dyah Kinasih Wuragil Eddy Rudianto Fadillah, Faqih Faishol, Faishol Fakris Muslim Fauliza, Tifa Femiana Gapsari MF Gian Suryanatha Hartawan Gunanti Mahasri Herly Evanuarini Iqbal, Ahmad Ismail, Mahrus Jibril Maulana Komarudin Komarudin Kris Witono M. Muhajir Malik Abdurrachman Manawan, Maykel Marsono Marsono Masera, Kemal Mito, Mohamed T Mufidah, Rhobithotus Muhamad Muhajir Muhamad Muhajir Muhamad Syaifuddin Muhammad Musa Muhammad Musa Muhammad Sumsanto Muhdi, Krisna Dwipa Murdanto, Putut Nanang Eko Wahyuningtiyas Nanang Eko Wahyuningtyas Nashrullah, Fikri Munif Navis, Akbar Nico Rahman Caesar Nusantara, Fajar Osman, Azlin Fazlina Pahlefi, Reval Panicker, Nithin Pradana, Yanuar Rohmat Aji Prasetya, Riduwan Pratama, Daniel Febrian Putra, Abyan Farras Rachmat Setiawibawa Ramadhan, Rahmad Ikrom Reddy .A. Dharmabintara Redyarsa Dharma Bintara Retno Wulandari Riyanto, Mochammad Deny Rizali, Dede Rr. Poppy Puspitasari Rudy Soenoko S.M.Shahrul N.S. Zahari Setyayunita, Tamaryska Sias, Quota Alief Subhan, Muhammad Ferindin Nuha Sudarno, Kurnia Agung Sukarni Sukarni Sukarni Sukarni Suprayitno Suprayitno Suprayitno Suprayitno Susilo, Bili Darnanto Syahtaria, Moh Ikhwan Tito Arif Sutrisno Uksan, Arifuddin Ulhaq, Ulfieda Anwar Utari, Inpita Casuarina Eqisetia Wardani, Nezya Pramudya Wiguna, Chrisrulita Sekaradi Wuragil, Dyah Kinasih Yanuar. R. A. Pradana Yanuhar, Uun Yudy Surya Irawan