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All Journal Jurnal Sains dan Teknologi Dentika Dental Journal Health Notions International Journal of Natural Science and Engineering JURNAL ANALIS LABORATORIUM MEDIK Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Poltekita: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Sangkareang Mataram Muhammadiyah Medical Journal Jurnal Kesehatan Gigi (Dental Health Journal) Jurnal Pengabmas Masyarakat Sehat JURNAL SKALA HUSADA: THE JOURNAL OF HEALTH Jurnal Info Kesehatan
I Gusti Agung Ayu Dharmawati
Poltekkes Kemenkes Denpasar
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Penyuluhan Penyakit Tidak Menular Dan Pemeriksaan Kesehatan Bagi Pemangku di Kawasan Suci Pura Agung Besakih Habibah, Nur; Dharmawati, I Gusti Agung Ayu; Dhyanaputri, I Gusti Ayu Sri; Burhannuddin, Burhannuddin; Bekti, Heri Setiyo; Sundari, Cokorda Dewi Widhya Hana; Arjani, Ida Ayu Made Sri; Mastra , Nyoman; Kurniawan, Surya Bayu
Jurnal Pengabdian Kepada Masyarakat (JPKM) TABIKPUN Vol. 5 No. 2 (2024)
Publisher : Faculty of Mathematics and Natural Sciences - Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpkmt.v5i2.158

Abstract

Pura Agung Besakih merupakan Pura Agung terbesar di Bali tempat persembahyangan umat Hindu sekaligus menjadi tujuan wisata. Para pemangku yang bertugas memimpin persembahyangan di pura tersebut sebagian besar berusia lebih dari 50 tahun dan termasuk dalam kelompok berisiko penyakit tidak menular (PTM). Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan tentang PTM serta melakukan pemeriksaan tekanan darah dan kolesterol total. Kegiatan dilakukan dengan beberapa tahapan yaitu sosialisasi, penyampaian materi, pemeriksaan kesehatan dan konsultasi hasil pemeriksaan. Hasil kegiatan menunjukkan bahwa terjadi peningkatan pengetahuan tentang PTM. Pemeriksaan terhadap para pemangku menunjukkan diagnosa tekanan darah normal dan tinggi, sedangkan kadar kolesterol terdiagnosa normal, di ambang batas dan tinggi. Kegiatan ini diharapkan dapat dilanjutkan dengan pendampingan untuk menindaklanjuti aktivitas yang dilakukan dalam mencegah kejadian PTM.
A Patient with Suspect Chronic Myeloid Leukemia: A Case Report Dharmawaiswari, Anak Agung Ayu Ratih; Tedja, I Gusti Ayu Wiradari; Prianggandanni, Made Ayu Vita; Dharmawati, I Gusti Agung Ayu; Bekti, Heri Setiyo
Muhammadiyah Medical Journal Vol 5, No 2 (2024): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.5.2.116-121

Abstract

Chronic myeloid leukemia (CML) is a type of cancer that starts in the blood-forming cells of the bone marrow. In contrast to other types of leukemia, chronic myeloid leukemia (CML) progresses slowly. This report covers a 52-year-old male patient who came to the emergency room at Wangaya Regional Hospital with weakness, nausea, and pallor. His weight had drastically decreased over the last few months. The clinical condition of the patient was that both eyes appeared anemic, and the abdominal examination revealed hepatomegaly. Complete blood count examination results showed the following results: leukocytes 222.73x103/µl, hemoglobin 7.3 g/dL, platelets 679x103/µl, neutrophil 87.5%, neutrophil/lymphocyte ratio 16.66%. The results of peripheral blood smear analysis showed that hyperleukocytosis, with the maturation stage of myelocyte cells with a percentage of myeloblasts 6%, promyelocytes 7%, myelocytes 6%, metamyelocytes 8%, neutrophils 10%, neutrophil segments 60%, other cells 3%. These examination results suggest chronic myeloid leukemia. However, to confirm the diagnosis, the BCR-ABL fusion protein must be expressed, which can be used to identify the presence or absence of the Philadelphia chromosome in patients diagnosed with chronic myeloid leukemia (CML).
Effectiveness of Giving Chitosan on Interleukin-6 and Mallondhyaldehide Levels in Wistar Rats with Chronic Periodontitis Dharmawati, I Gusti Agung Ayu; Mastra, Nyoman; Supariani, Ni Nyoman Dewi; Ratih, Gusti Ayu Made; Artini, Ni Putu Rahayu
International Journal of Natural Science and Engineering Vol. 7 No. 1 (2023): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/ijnse.v7i1.53897

Abstract

The 6th highest diseases that occur in Indonesian society include dental caries and periodontitis caused by dental plaque which is a breeding ground for bacteria such as Streptococcus mutants and Phorphyromonas gingivalis. The purpose of this study was to determine the effectiveness of chitosan on levels of Interleukin-6 and Malondhyaldehyde (MDA), as an anti-inflammatory marker using the Elisa test. The research method was a true experimental randomized posttest only control group design, with 3 treatment groups namely control, 2% chitosan gel, and 100mg/200g/bb of chitosan orally in 15 Wistar rats with periodontitis induced by Phorphyromonas gingivalis bacteria. The results showed that the mean levels of Interleukin-6 and Mallondhyaldehyde were significantly different (p<0.05) between the control group, chitosan gel treatment, and oral chitosan administration Interleukin-6 levels were the highest in the chitosan gel (8.3091±1.25570), the control average (5.8523±0.51512), the lowest oral average (3.2563±1.45952). Similarly, Mallondhyaldehyde levels were highest in the gel group (2.8850±0.19353), control group (2.2284±0.00914), and oral group (1.2943±0.60280).). Based on these results, oral chitosan was the most effective in the treatment of periodontitis.
Uji Ekstrak Daun Cemcem Dalam Menghambat Pertumbuhan Bakteri Phorphyromonas Gingivalis Bekti, Heri Setiyo; Dharmawati, I Gusti Agung Ayu; Habibah, Nur
JST (Jurnal Sains dan Teknologi) Vol. 11 No. 2 (2022)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.368 KB) | DOI: 10.23887/jstundiksha.v11i2.49457

Abstract

Cemcem atau Spondias pinnata (L.f) Kurz merupakan obat tradisional yang sering digunakan oleh masyarakat Bali. Beberapa penelitian menunjukkan bahwa ekstrak daun Cemcem memiliki aktivitas antibakteri. Periodontitis merupakan penyakit gigi dan mulut yang banyak diderita masyarakat Indonesia. Salah satu penyebab periodontitis adalah P. gingivalis. Tujuan penelitian ini adalah untuk mendeteksi kandungan senyawa bioaktif dan daya hambat ekstrak etanol daun Cemcem terhadap pertumbuhan P. gingivalis. Ekstraksi daun Cemcem dilakukan dengan teknik maserasi menggunakan pelarut etanol 96%. Untuk mendeteksi kandungan senyawa bioaktif dilakukan uji fitokimia terhadap senyawa alkaloid, flavonoid, terpenoid, steroid, dan tanin. Uji daya hambat ekstrak etanol daun Cemcem dilakukan menggunakan metode difusi cakram dengan kontrol positif yaitu khlorheksidin 2%, kontrol negatif yaitu etanol, serta dua konsentrasi ekstrak yaitu 60% dan 80%. Hasil penelitian menunjukkan bahwa ekstrak etanol daun Cemcem mengandung senyawa bioaktif yaitu alkaloid, flavonoid, steroid, dan tannin. Zona hambat yang terbentuk memiliki perbedaan bermakna antara ketiga perlakuan dan masuk dalam kategori kuat. Berdasarkan hasil penelitian ekstrak etanol daun Cemcem berpotensi sebagai obat herbal untuk periodontitis.
Persistence of Antibody Response Against SARS-CoV-2 After Vaccination Bekti, Heri Setiyo; Habibah, Nur; Dharmawati, I Gusti Agung Ayu; Merdekawati, Fusvita; Noviar, Ganjar
JURNAL INFO KESEHATAN Vol 21 No 4 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss4.1066

Abstract

SARS-CoV-2 is the causative agent of the disease known as COVID-19. COVID-19 is spreading very fast around the world. One of the immune responses that play a role in against SARS-CoV-2 infection is the production of antibodies, which is 3 weeks after infection. Where within 3 weeks after infection, antibodies will be produced against RBD and the S1 and S2 domains in glycoprotein S and nucleocapsid protein N. The ability of an antibody to inhibit viral infection is determined by its level or titer. This study aims to determine the description of antibody levels against SARS-CoV-2 after vaccination. This type of research is descriptive research. Measurement of antibody levels for SRBD SARS-CoV-2 was carried out using the CLIA method using the MAGLUMI tool. Of the 30 respondents, 23 people had received the third vaccine. The results of this study showed that the average level of SRBD antibodies against SARS-CoV-2 in respondents with 2 doses of vaccine (1.063,786 BAU/mL) was higher than in respondents with 3 doses of vaccine (535.651 BAU/mL). Vaccine intervals of more than 6 months (908.338 BAU/mL) have higher antibody levels than respondents with vaccine intervals of 1-6 months (228.006 BAU/mL). The conclusion of this study is the highest antibody titers are produced >6 months after vaccination, antibody titers are still detectable after 12 months of vaccination, and for further research, it can be measured antibody levels against SARS-CoV-2 from people who have got vaccination for a duration of 2 years or more.
The Development of Spondias pinnata (L.f) Kurz. Leaf Extract Toothpaste: Formulation, Physical Properties Evaluation and its Antibacterial Efficacy Against Streptococcus mutans Bacteria Habibah, Nur; Bekti, Heri Setiyo; Dewi, Ni Nyoman Astika; Dharmawati, I Gusti Agung Ayu; Krisna, Luh Ade Wilan; Mahastuti, Shri Ayu Purnami
JURNAL INFO KESEHATAN Vol 22 No 4 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss4.1669

Abstract

Cemcem (Spondias pinnata (L.f) Kurz) is a native Indonesian plant that has long been used as a traditional medicine. The ethanol extract of S. pinnata contains alkaloids, carbohydrates, flavonoids, triterpenoids, steroids, tannins, resins, and saponins. It has proven antibacterial activity against gingivitis and periodontitis bacteria, such as Streptococcus mutans. This study aims to develop a toothpaste formula with the active ingredient of S. pinnata leaf extract with various concentrations of 5, 15, and 30%; evaluate its properties; and measure its antibacterial effectiveness against Streptococcus mutans. The research method used a quasi-experimental method with a post-test-only control group design. The S. pinnata leaves were extracted with 96% ethanol solvent using the maceration technique. The properties of the toothpaste were evaluated based on homogeneity, spreadability, foam height, viscosity, and pH. The liking test was conducted to assess color, taste, scent, and texture based on the perception of 30 panelists. Antibacterial activity was tested using the well diffusion method. The test results confirm that all preparation formulas are homogeneous, the foam height is in the range of 4.33 - 21.33 cm, the spreadability is in the range of 3.44 - 4.53 cm2, the viscosity of toothpaste is in the range of 20767-67600 cps, and the pH value is in the range of 4.82 - 7.59. The results showed that toothpaste containing 5% of S. pinnata leaf extract met the physical and pH requirements and was most favored by panelists. This formula also showed antibacterial activity against S. mutans with an average inhibition zone diameter of 7.72 mm ± 0.439. Based on the study's results, it can be concluded that toothpaste containing 5% S. pinnata leaf extract effectively inhibits the growth of S. mutans bacteria by 54.33% compared to the positive control. Further research is suggested to optimize the concentration of S. pinnata leaf extract to maximize its antibacterial activity, without affecting its physical quality and organoleptic acceptance.
Overview of Blood Glucose Levels at Posyandu Elderly in UPTD Abiansemal III Public Health Center Working Area. Mastra, Nyoman; Sri Arjani, Ida Ayu; Dharmawati, I Gusti Agung Ayu
Jurnal Pengabmas Masyarakat Sehat Vol 5, No 3 (2023): JULI
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jpms.v5i3.2550

Abstract

The success of health development in Indonesia has an impact on increasing Life Expectancy. One of the promotive and preventive efforts to increase life expectancy is through the establishment of posyandu for elderly. In the working area of UPTD.Puskesmas Abiansemal III there are 23 Posyandu with the number of elderly aged 60-69 years as many as 1201. Activities carried out at Posyandu for the elderly are in form of exercise and measuring blood pressure. As an effort to increase life expectancy in elderly, the devotees carry out activities in form of measuring blood glucose levels, with the aim that data obtained can be used as an initial screening for prevention of Diabetes Mellitus in elderly.The implementation of community service is carried out by providing counseling and checking blood glucose levels for elderly at Elderly Posyandu, at Lateng Service of Sibang Kaja Village. From results of examination of blood glucose levels, the target was 55 elderly belonging to the age group of 45-54, 55-65, 66-74, 75-90. The results of measuring blood glucose in elderly, obtained 48 people with normal blood glucose, 7 elderly people with high blood glucose. Based on the criteria for normal blood glucose, mostly young elderly (Young Old) are 23 people, while the criteria for high blood glucose are mostly in Elderly, which are 3 people. The data on findings of measuring blood glucose levels in elderly is expected to be a policy by Puskesmas for promotive and preventive activities for the health of elderly.
GAMBARAN KADAR KREATININ SERUM PADA PEMINUM TUAK DI DESA SANGEH KABUPATEN BADUNG Indrasari, Dewa Ayu Ratna Putri; Dharmawati, I Gusti Agung Ayu; Habibah, Nur
Jurnal Skala Husada : The Journal of Health Vol 20, No 2 (2023): JSH: Jurnal Skala Husada-The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v20i2.3074

Abstract

Tuak merupakan salah satu minuman tradisional beralkohol produksi lokal Bali. Kandungan alkohol pada tuak sekitar 4%. Konsumsi tuak secara terus menerus tentunya akan beresiko terhadap kesehatan ginjal. Salah satu pemeriksaan laboratorium untuk menilai fungsi ginjal adalah melalui pemeriksaan kadar kreatinin serum. Penelitian ini bertujuan untuk mengetahui gambaran efek minuman tuak terhadap kreatinin serum. Desain penelitian ini adalah  crossestional study pada peminum tuak di Banjar Brahmana Desa Sangeh, Kabupaten Badung. Sampel penelitian sebagian besar laki-laki peminum tuak sebanyak 37 orang. Metode pemeriksaan kadar kreatinin serum dengan Jaffe Reaction. Hasil penelitian menunjukkan kadar kreatinin serum tinggi sebanyak 54% dan  kadar kreatinin normal 46%. Berdasarkan kelompok umur, kadar kreatinin tinggi terbanyak, pada kelompok usia (54- 66) tahun sebanyak 24-32%. Berdasarkan jumlah konsumsi tuak, kadar kreatinin tinggi terbanyak, terjadi pada kategori sedang (1-4 botol/ 620ml-2.480ml) yaitu sebanyak 37,8%.. Berdasarkan lama konsumsi, kadar kreatinin tinggi terbanyak pada lama konsumsi 5 tahun sebanyak 43%. Kesimpulan hasil penelitian ini sebagian besar peminum tuak mempunyai kadari kreatinin tinggi
Co-Authors Arjani, Ida Ayu Made Sri Burhannuddin Cokorda Dewi Widhya Hana Sundari Dewi, Ni Nyoman Astika Dharmawaiswari, Anak Agung Ayu Ratih Gusti Ayu Ari Purnamadewi Heri Setiyo Bekti I Gede Surya Kencana I Gusti Agung Ayu Putu Swastini I Gusti Agung Dewi Sarihati I Gusti Ayu Agung Putu Swastini I Gusti Ayu Raiyanti I Gusti Ayu Sri Dhyanaputri I Nyoman Gejir I Nyoman Wirata I Wayan Juniarsana Ida Bagus Oka Suyasa Indrasari, Dewa Ayu Ratna Putri Kurniawan, Surya Bayu Luh Ade Wilan Krisna Mahastuti, Shri Ayu Purnami Mastra , Nyoman mastra, nyoman Merdekawati, Fusvita Ni Kadek Ayu Cintia Risqi Ni Made Sirat Ni Made Widhiasti Ni Nyoman Dewi Supariani Ni Putu Rahayu Artini Noviar, Ganjar Nur Habibah Nyoman Mastra Prianggandanni, Made Ayu Vita putri, sagung Ratih, Gusti Ayu Made Siti Fatimah Sri Arjani, Ida Ayu Supariani, Ni Nyoman Dewi Tedja, I Gusti Ayu Wiradari