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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Nexus Pendidikan Kedokteran dan Kesehatan Nexus Kedokteran Komunitas Nexus Kedokteran Klinik Nexus Biomedika Nexus Kedokteran Translasional Jurnal Riset Kesehatan Folia Medica Indonesiana WACANA Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya JOURNAL SCIENTIFIC OF MANDALIKA (JSM) Plexus Medical Journal
Nanang Wiyono
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Arts Humanities Biochemistry, Genetics & Molecular Biology Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Correlation between Working Memory Capacity with Anatomy Point of Medical Studies Program in Faculty of Medicine Sebelas Maret University Rifqi Hadyan; Nanang Wiyono; Dian Nugroho
Nexus Pendidikan Kedokteran dan Kesehatan Vol 4, No 1 (2015): Nexus Pendidikan Kedokteran & Kesehatan
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Anatomy is one of the basic field of study in faculty of medicine (basic medical sciences), who will become the basic of clinical studies. Anatomy learning process influenced by working memory capacity. Working memory have a very important effect in human mental development including cognitive ability, the ability of human to plan something, to find solution, and to understand new things. Working memory is one of the cognitive ability that influence the study achievement. Methods: This study was an observational analytic study with cross sectional approach thar held at October, 6th, 2014 at Faculty of Medicine Sebelas Maret University with 61 respondents of third semester . The sampling was done by random sampling technique. The selection of sample done by checking the inclusion and exclusion criteria of this study sample. The amount of ample obtained statistically analyzed by using Pearson correlation test. Result: The result of Pearson correlation test was found that there were a significant correlation between working memory capacity with Anatomy Point of Medical Studies Program Third Semester Student in Faculty of Medicine Sebelas Maret University (p = 0.000) and the correlation between variables were moderate (r = 0.600) with positive direction of correlation. Conclusion: The correlation between working memory capacity and Anatomy Point of Medical Studies Program Faculty of Medicine Sebelas Maret University is significant. Keywords: Working Memory Capacity, Anatomy Point
The Correlation between Sleep Quality and Working Memory Capacity on Student of Senior High School Ardian Pratiaksa; Nanang Wiyono; Sinu Andhi Jusup
Nexus Kedokteran Komunitas Vol 5, No 2 (2016): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Sleep is an active, repetitive and reversible behaviour serving several different function, one of it is the function to develop memory s abbility. Lack of sleep is one of big problem faced by the modern society nowadays. In the big city like Jakarta, most of the adolescents have sleep disorder. This research intents to prove correlation between sleep quality and working memory capacity on student of Senior High School. Methods: This research was a cross-sectional analytic observational. The population sample was students in the 10th grade of 4 Surakarta Senior High School. By using purposive sampling method, the total restricted samples were 66 students. The instruments were Pittsburgh Sleep Quality Index, which is used to check the sleep quality scores, and Reading Span Test, to check the working memory capacity. Data was analyzed by Spearman Correlation test. Results: The respondents were 66 students, 33 students (50%) with bad sleep quality, 33 (50%) others were students with good sleep quality. The result showed high positive and significant correlation between sleep quality and working memory capacity (r = 0.814 and P = 0.000). Conclusions: There is high positive and significant statistic correlation between sleep quality and working memory capacity on students of senior high school. Keywords: Senior high school students, sleep quality, working memory capacity.
The Correlation between Physical Activity and Working Memory Capacity on Medical Student of Sebelas Maret University Hernowo Setyo Utomo; Selfi Handayani; Nanang Wiyono
Nexus Kedokteran Komunitas Vol 5, No 2 (2016): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Physical activity affects brain structure and function through 3 common mechanisms: angiogenesis; neurogenesis; and regulation of neurotrophic factors. Working memory capacity is one aspect of brain function describing human intelligent which is affected by the structure and function of the brain. The aim of research was to prove that physical activity could affect working memory capacity. Methods: This research was a cross-sectional observational analytic. It had been done at Medical Faculty of Sebelas Maret University on July, 2014. The data was collected by using purposive sampling method. All responden had to fill questionnaire of Lie Scale Minnesota Multiphasic Personality Inventory (L-MMPI) in order to know the honesty level, International Physical Activity Questionnaire (IPAQ) to measure the level of physical activity during a week and reading span test to measure working memory capacity. The final result of restricted samples was 105. The data was analyzed by Spearman Correlation Test. Results: IPAQ score showed that 15.24% samples were in low level physical activity, 50.47% were in medium level physical activity, and 34.29% were in high level physical activity. Reading span test result were 93.33% samples were in high working memory capacity and the other 6.67% were in low working memory capacity. Both variables then examined by Spearman correlation test with p result 0.441 and r = -0.076 Conclusions: There is unsignificant statistic correlation between physical activity and working memory capacity on Medical Student of Sebelas Maret University Keywords: physical activity, working memory capacity, medical student
The Correlation between Estimation of Cranial Capacity and Working Memory Capacity in Elementary Students in Surakarta Reza Yunita Sari; Nanang Wiyono; Andri Iryawan
Nexus Biomedika Vol 4, No 1 (2015): Nexus Biomedika
Publisher : Nexus Biomedika

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Abstract

Background: In children, the increasing of cranial capacity and the maturation of working memory capacity happen. The increasing of cranial capacity is driven by the growth of brain. The growth and the maturation of brain will influence someones intelligence. The working memory capacity is one of the most important domains of intelligence. This research aimed to determine the correlation between the estimation of cranial capacity and the working memory capacity. Methods: This research was a descriptive analytical study which used cross sectional approach. The subjects of this study were 5th grade students at Kristen Manahan Elementary School. This research was done in 36 males of students by measuring cranial capacity and doing Reading Span Test for measuring working memory capacity. The collected data were analyzed with the Saphiro Wilk Normality Test and the Pearson Correlation. Results: The result of analysis showed r = 0.367 and p = 0.027, which meant that there was weak-powered correlation between the estimation of cranial capacity and the working memory capacity in the elementary students in Surakarta and this correlation was statistically significant. Conclusions: From this research, it is concluded that there is statistically significant correlation between the estimation of cranial capacity and the working memory capacity in the elementary students in Surakarta (r = 0.367). Keywords: Estimation of cranial capacity; working memory capacity; elementary student
Relationship Between Dermatoglyphic Patterns and ?-Thalassemia Major Disease Nisa'u Luthfi Nur Azizah; Selfi Handayani; Nanang Wiyono
Nexus Kedokteran Translasional Vol 4, No 2 (2015): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: ?-Thalassemia major is the most common severe thalassemic disease in the world. Children with ?-Thalassemia major have to be identified and treated soon to prevent the worse prognosis of the disease. One of the screening methods to establish thalassemic diagnosis is by observing dermatoglyphic patterns. The aim of this study was to determine the relationship between dermatoglyphic patterns and ?-Thalassemia major disease. Methods: This study was an observational analytic study with cross sectional design. This study located in Poliklinik Anak and SMF Anak RSUD Dr. Moewardi Surakarta. The sampling technique used purposive sampling based on the characteristics of population that have been known previously. The subjects were 20 patients of ?-Thalassemia major and 20 non- ?-Thalassemia major. Data were obtained through direct scanning the subjects fingerprints using scanner. Statistical analysis used independent-sample t test, Mann-Whitney test and chi square test. Results: From the analysis, this study found there was no significant difference of the ridge count between patients and control group (p > 0.05). However, there was significant difference of the patterns between patients and control group (p < 0.05). The number of whorl patterns in ?-Thalassemia major patients was 53,5%, it greater than that in normal individuals (20,5%). Loop patterns were less frequent in ?-Thalassemia major patients (34%) compared to normal individuals (75,5%). Arch patterns had no significant difference between patients and control group (p > 0.05). Conclusions: There was a significant relationship between dermatoglyphic patterns and ?-Thalassemia major disease. Keywords: ?-thalassemia major, dermatoglyphic, fingerprint
Effect of EthanolicExtract of Centella asiatica againts Adrenal Gland CortexCell Lipid Droplet Feature Induced by Chronic Immobilization Stress in Rats Mochammad Fairuz Zahran; Brian Wasita; Nanang Wiyono; Ratih Puspita Febrinasari
Nexus Kedokteran Translasional Vol 4, No 1 (2015): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Chronic stress can increase the lipid droplet in cortex cell and adrenal gland damage. Pegagan extract contains such as asiaticoside, flavonoids and triterpenoid are known have antioxidant effect. The objective of the present study was to investigate the beneficial effects of Ethanolic Extract of Centella asiatica (EEC) on adrenal gland cortexcell lipid droplet feature induced by immobilization stress in male rats. Method: This study was a laboratory experimental study with randomized post test only control group design. Paraffin blocks from thirty five male rats previously subjected with chronic immobilization stress and then divided into 6 groups: control group given distilled water 1 mg/kg, stress + PGA, stress + 150 mg/kg EEC, stress + 300 mg/kg EEC, stress + 600 mg/kg EEC and stress + fluoxetine 10 mg. The treatments were performed for 21 consecutive days. Lipid droplet was evaluated using Scoring Lipid Content from Hematoxylin Eosin staining. Statistic analysis was performed using Kruskall-Wallis test continued by Post Hoc Mann-Whitney Test with Bonferroni correction. Result: Results of Kruskall Wallis test showed significant differences in six groups with p = 0.000. Mann Whitney test with Bonferroni correction showed a significant difference between control group with stress + PGA and stress + 600 mg/kg EEC. Fluexetine as positive control show the most effective dose in this study (p = 0,000). There were no significant difference between fluoxetine as control positive and control group (p = 0,112). Conclusion: Stress + 600 mg/kg EEC has beneficial effect on preventing adrenal gland cortexcell lipid droplet feature induced by chronic immobilization stress in rat. Keywords : Centella asiatica, chronic immobilization stress, adrenal glands lipid droplet feature
DECREASED PAIN SCALE BASED ON CRITICAL PAIN OBSERVATION TOOL (CPOT) AND BEHAVIORAL PAIN SCALE NON-INTUBATED (BPS-NI) IN PATIENTS WITH REDUCED CONSCIOUSNESS BY CLASSICAL MUSIC INTERVENTION IN UNS HOSPITAL Muchtar Hanafi; Faizal Muhammad; Nanang Wiyono; Betty Saptiwi
Jurnal Riset Kesehatan Vol 8, No 2 (2019): NOVEMBER 2019
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (297.609 KB) | DOI: 10.31983/jrk.v8i2.5119

Abstract

Patient with reduced consciousness needs attention to their comfort as well as pain during treatment. Listening to classical music caused relaxation and pain reduction. This study aimed to determine the effect of classical music on the CPOT score, BPS-NI, and cortisol levels in patients with reduced consciousness. The research was conducted by using a pretest-posttest control group design. 18 patients were divided into the control group (C) and the classical music group (M). Classical music was played for 3 days respectively that consisted of 3 sessions per day. Furthermore, each patient was tested for cortisol levels on the third day. Comparative test of mean difference between pre-intervention and post-intervention obtained significant results in CPOT (p= 0.000) and BPS-NI (p= 0.001) measurements in all groups. Tukey's post-hoc test obtained significant results in which the M group had a lower mean score. The mean of cortisol level was higher in M group (14.7 μg/dL) compared to the C group (12.96 μg/dL), although not significant statistically (p= 0.67). Listening to classical music for patients with reduced consciousness decreased the pain scale. This was supported by the average of cortisol levels that were higher in the M group, considering that cortisol was a hormone that prevents pain.
Electroacupuncture attenuates working memory impairement after chronic stress exposure in rat Selfi Handayani; Nanang Wiyono
JURNAL KEDOKTERAN DAN KESEHATAN Vol 4, No 3 (2017)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Chronic stress (CS) exposure causes cytogenic and structural changes in the hipocampus which lead to cognitive impairment. Acupuncture has been shown to reduce cortisol secretion and protects hipocampus from stress-related damage. We hypothesize that acupunture can alleviate stress-induced working memory deficit.mthis study aimed to investigate whether electroacupuncture (EA) can improve memory in chronic stress model in rat. This was an experimental study with pretest and postest control group design. Rats were divided randomly into four groups: control group (C), CS group (T1), EA group (T2), and EA plus CS group (T3). Working memory was assessed using Eight-arm radial maze. A marked decrease in working memory was observed in the CS group demonstrated by more working memory correct errors (p=0.020) and incorrect errors (p=0.024) than control group. The CS plus EA rats made fewer working memory correct error (p=0.001) and incorrect error (p=0.000) compared to the CS only group. EA treatment in non-stressed rats did not significantly improve working memory compared to control. Chronic stress decreases working memory in rats. EA treatment at Baihui (DU 20) and Zusanli (ST 36) significantly attenuates stress induced working memory deficits in rats.
Hubungan Endometriosis dengan Dismenore pada Pasien Poliklinik Obstetri dan Ginekologi di RSUD Dr. Moewardi Dian Fikri Rachmawan; Tedja Danudjo Oepomo; Nanang Wiyono
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Generally, reproductive-aged and unpregnant women experience menstruation which is able to be accompanied by dysmenorrhea. Dysmenorrhea prevalence ranged from 1.7% 97% in 106 studies, which is involving 125.249 women. In 20 high-quality studies with representative samples, dysmenorrhea prevalence was reported between 16.8% 81%. Approximately, there were 60% 70% of Indonesian women who experienced dysmenorrhea during menstruation with 15% of them complained that their activities were limited due to dysmenorrhea. One of the significant risk factors that cause dysmenorrhea is endometriosis. Nevertheless, there is no definitive data on dysmenorrhea caused by endometriosis in Indonesia. In fact, endometriosis would greatly impact the quality of life of a woman. The present study aims to determine the association between endometriosis and dysmenorrhea among patients admitted on the Obstetrics Gynecology Clinic of RSUD Dr. Moewardi. Methods: The present study was as an analytical observational study with cross sectional approach. A total of 45 subjects were selected from medical records of RSUD Dr. Moewardi by stratified random sampling technique, which subsequently were divided into 2 groups, namely; 15 patients of endometriosis group and 30 patients of gynecologic malignancies other than endometriosis group. Data was collected by interviewing patients and asking them to fill out the questionnaire. Data was analyzed by using Chi Square test and processed with Statistical Product and Service Solutions (SPSS) 19.00 for Windows. Results: Chi Square test showed OR = 24,182; CI 95% = 2,788 209,764; and p = 0,000. Patients diagnosed by endometriosis are at risk for dysmenorrhea 24,182 times greater than patients with gynecologic malignancies other than endometriosis. Conclusions: There is a significant association between endometriosis and dysmenorrhea among patients admitted on the Obstetrics Gynecology Clinic of RSUD Dr. Moewardi. Keywords: Endometriosis, dysmenorrhea, stratified randim sampling.
PENGARUH MENDENGARKAN AYAT-AYAT AL QURAN TERHADAP PENURUNAN STRES PADA PASIEN KANKER SERVIKS Iis Fitriatun; Nanang Wiyono; Arif Tri Setyanto
Wacana Vol 7, No 2 (2015)
Publisher : UNS Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.695 KB) | DOI: 10.13057/wacana.v7i2.84

Abstract

Pengaruh Mendengarkan Ayat-ayat Al Quran terhadap Penurunan Stres pada Pasien Kanker Serviks The Effect of Listening to The Verses The Quran to Decrease Stress on The Cervical Cancer Patients Iis Fitriatun, Nanang Wiyono, Arif Tri Setyanto Program Studi Psikologi Fakultas Kedokteran Universitas Sebalas Maret ABSTRAK Pasien kanker serviks yang menjalani kemoterapi harus menjalani hospitalisasi di rumah sakit. Intervensi medis, dampak yang ditimbulkan dari intervensi medis, proses hospitalisasi rentan menjadi sumber stres bagi pasien kanker serviks. Individu merespon stres melalui dua jalur yaitu respon psikologis dan fisiologis. Respon psikologis akan termanifestasikan dengan adanya ketakutan, ketidakberdayaan dan kecemasan. Sedangkan respon fisiologis terhadap stres akan mengaktifkan respon HPA aksis untuk mensekresikan hormon kortisol. Semakin tinggi stres yang dialami maka akan meningkatkan sekresi hormon kortisol oleh kelenjar adrenal. Hormon kortisol dapat diukur dengan menggunakan sampel saliva individu dan dianalisis dengan teknik ELISA. Pendekatan intervensi klinis bagi pasien hendaknya dilakukan secara holistik dengan mempertimbangkan aspek psikospiritual. Salah satu pendekatan psikologi yang mulai dikembangkan dalam bidang intervensi klinis adalah dengan menggunakan terapi musik. Terapi musik memiliki pengaruh yang efektif untuk menurunkan stres (Mucci & Mucci, 2002; O’Callaghan, 2006; Dewi, 2009) Ayat-ayat Al Quran yang dibacakan sesuai dengan kaidah tajwid dapat memberikan efek relaksasi seperti terapi musik bagi yang mendengarkannya sehingga ayat-ayat Al Quran yang dibacakan sesuai kaidah tajwid dapat menurunkan stres. Penelitian ini bertujuan untuk mengetahui pengaruh mendengarkan ayat-ayat Al Quran dalam menurunkan stres dan kadar kortisol pada pasien kanker serviks. Desain penelitian yang digunakan dalam penelitian ini adalah single case experimental design dengan metode studi kasus. Perlakuan mendengarkan ayat-ayat Al Quran diberikan sebanyak lima kali dalam lima hari. Hasil penelitian ini menunjukkan nilai signifikansi sebesar 0,022 untuk Skala Stres dan 0,090 untuk kadar kortisol dengan taraf signifikansi 0,05. Maka dapat disimpulkan bahwa mendengarkan ayat-ayat Al Quran memiliki pengaruh yang signifikan untuk menurunkan stres psikologis dan tidak memiliki pengaruh yang signifikan untuk menurunkan kadar kortisol pada pasien kanker serviks. Kata kunci: Stress, ayat-ayat Al Quran, kortisol.
Co-Authors Agus Sugeng Riyanto Ahmad Isnaini Shidqi Nurhani Andri Iryawan Annisa Aghnia Rahma Ardian Pratiaksa Arif Tri Setyanto Betty Saptiwi Brian Wasita Brian Wasita Dhoni Akbar Ghozali Dian Fikri Rachmawan Dian Nugroho Dwi rahayu Elang Jordan Ibrahim Enrico Ananda Budiono Faizal Muhammad Hastami, Yunia Hernowo Setyo Utomo Iis Fitriatun Kristanto Yuli Yarso Lukman Aryoseto Mochammad Fairuz Zahran Muchtar Hanafi Muchtar Hanafi Muhammad Syauqi Ridhallah Muhana Fawwazy Ilyas Nisa&#039;u Luthfi Nur Azizah Rachmi Fauziah Rahayu Raditya Perdana Aryasatya Ratih Dewi Yudhani Ratih Puspita Febrinasari Reza Yunita Sari Rifqi Hadyan Riza Novierta Pesik Selfi Handayani Sinu Andhi Jusup Siti Munawaroh Suyatmi Suyatmi Syania Shabrina Tedja Danudjo Oepomo