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Studi Literatur: Potensi Tanaman Belimbing Wuluh dalam Menurunkan Tekanan Darah Penderita Hipertensi Ahmad Yani; Venny Patricia
Jurnal Kesehatan Manarang Vol 8 No 1 (2022): April 2022
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v8i1.481

Abstract

The high prevalence of hypertension still encourages research to find blood pressure-lowering drugs, especially those derived from natural ingredients. One of the plants that have been reported to have the potential to reduce blood pressure is the bilimbi (Averrhoa bilimbi L.). Observations of the antihypertensive activity of this plant have been carried out, both from the use of leaves and fruit. However, several existing studies have shown that the dose of using the leaves and fruit of bilimbi still varies with varying levels of effectiveness, so the effective dose of this plant utilization remains unknown. This study aims to see the efficacy of bilimbi in lowering blood pressure and determine the most effective dose for its use. The literature selection was carried out by searching the Google Scholar database, the Garba Rujukan Digital portal (Garuda), ScienceDirect, Pubmed, and Directory Open Access Journals (DOAJ) using predetermined keywords. Then, the identification and screening of articles based on duplication and inclusion criteria were carried out. The study results showed that the fruit had higher effectiveness in lowering blood pressure than the leaves. This literature study concluded that consuming 100 ml of bilimbi fruit juice regularly for 14 days may lower the blood pressure up to 34 mmHg.
Pemberdayaan Pemuda dalam Optimalisasi Layanan Digital BPJS Kesehatan Melalui Edukasi dan Pelayanan Masyarakat di Wilayah Desa Citorek Tengah Nurmeily Rachmawati; Venny Patricia; Ahmad Yani; Muhamad Abdul Rifai
BANTENESE : JURNAL PENGABDIAN MASYARAKAT Vol. 5 No. 1 (2023): Bantenese : Jurnal Pengabdian Masyarakat
Publisher : Pusat Studi Sosial dan Pengabdian Masyarakat Fisipkum Universitas Serang Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30656/ps2pm.v5i1.6284

Abstract

Perkembangan era digitalisasi dan teknologi membuat layanan kesehatan juga mengikuti arus perkembangan teknologi. Layanan digital berbasis 4.0 menjadikan baik pembuat layanan dan pengguna harus dapat menggunakannya dengan optimal. Tingkat pengetahuan dan literasi masyarakat di Indonesia yang berbeda-beda menyebabkan kurangnya pemanfaatan layanan digital KIS. Berdasarkan hasil survey di Desa Citorek, Banten ditemukan beberapa permasalahan terkait KIS ini diantaranya kesalahan identitas, lokasi cukup jauh ke kantor BPJS, dan minimnya pengetahuan masyarakat tentang layanan digital BPJS. Tujuan kegiatan pengmas ini adalah mengoptimalisasi peran pemuda untuk dapat memanfaatkan layanan digital BPJS dan membantu masyarakat sekitar dalam memanfaatkan layanan digital tersebut. Tahapan kegiatan terdiri dari persiapan meliputi perencanaan, perizinan, dan survey lokasi. Pelaksanaan kegiatan dilakukan dengan bimbingan para pemuda, edukasi kepada masyarakat, dan evaluasi kegiatan dari hasil pre dan post test. Hasil kegiatan pengmas menunjukkan pengetahuan pemuda tentang layanan digital BPJS meningkat menjadi 51,85%, pemanfaatan layanan digital BPJS sebanyak 86 kali penggunaan, pemanfaatan layanan meluas hingga 6 desa lainnya, dan sebanyak 189 KIS telah dibantu diperbaiki melalui program layanan oleh pemuda setempat
IDENTIFIKASI METALLO-β-LACTAMASE (MBL) PADA ISOLAT BAKTERI GRAM NEGATIF DI RUMAH SAKIT KOTA PALEMBANG Venny Patricia; Ahmad Yani
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 18 No 1 (2023): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : POLITEKNIK KESEHATAN KEMENKES PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v18i1.1424

Abstract

Latar Belakang: Resistensi antibiotik merupakan ancaman bagi efektifitas pencegahan dan pengobatan terhadap penyakit infeksi. Antibiotik beta laktam ditemukan pertama kali sampai sekarang, angka kejadian infeksi oleh bakteri penghasil ESBL semakin meningkat diseluruh dunia. Ada 3 kelas menurut klasifikasi Ambler, diantara nya kelas B yaitu metallo-beta-lactamase (MBL) paling banyak menyebar dan banyak didominasi oleh bakteri Enterobactericeae yang merupakan bagian dari bakteri gram negatif. mengetahui prevalensi enzim Metallo beta lactamase (MBL) pada isolat bakteri gram negatif berdasarkan metode fenotif dan genotif sehingga akan didapatkan data terkait resistensi antibiotik ESBL khususnya Metallo-ꞵ-Lactamase. Metode: Penelitian ini berupa studi laboratorik dengan survei klinis secara cross sectional. Konfirmasi fenotif menggunakan Double-disk synergy test (DDST) dan Combined disk synergy test (CDST) dan secara genotif dengan mendeteksi gen IMP, VIM dan NDM. Hasil: Total 88 isolat didapatkan hasil uji DDST positif sebanyak 44(50%) isolat dan CDST sebanyak 87(98.8%) isolat. Konfirmasi MBL secara genotif didapatkan positif hanya pada gen IMP 7(7.9%) isolat, sedangkan pada gen VIM dan NDM semuanya negatif. Data secara fenotif pada sampel yang positif gen IMP, didapatkan sebagai berikut yaitu DDST positif sebanyak 4(4.5%) dan CDST positif sebanyak 7(7.9%). Sensitifitas dari perbandingan dua metode tersebut diperoleh hasil sebanyak 51.1% dan Spesifisitas sebanyak 100%. bakteri terbanyak yaitu K.pneumonia 45(51,1%) dan E.coli 31(35,2%). Sampel terbanyak sputum 34(38,6%); pus 18(20,5%) serta urine 13(14,8%). Kesimpulan: Metode konfirmasi secara fenotif yang lebih mudah dipakai yaitu menggunakan metode CDST dan masih terdapat gen positif MBL pada isolate gram negatif. Kata kunci : Fenotif, Genotif, Gram negatif, MBL
Description of The Risk Level of Heart Disease to The Ratio of LDL/HDL Patients at Rsud Dr. Adjidarmo Venny Patricia; Nining Kurniati; Citra Trisna; Nana Munawar
Journal of Noncommunicable Diseases Prevention and Control Vol. 1 No. 1 (2023): Journal of Noncommunicable Diseases Prevention and Control
Publisher : Hypertension Prevention and Control Research Center, The Polytechnic of Health of Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61843/jondpac.v1i1.497

Abstract

The increased risk of stroke is associated with high low-density lipoprotein (LDL) cholesterol, low high-density lipoprotein (HDL) cholesterol, and a high ratio of LDL and HDL cholesterol, and will be amplified if other stroke risk factors are present. The purpose of this study was to determine the ratio of LDL and HDL cholesterol in patients at RSUD Dr. Adjidarmo. The research design is descriptive research. With a total population of 150 people, a sample of 20% of the population, namely 30 people, was taken. The data collection technique in this study was primary data, namely through the medical records of heart patients who had received outpatient care at the Cardiac and Vascular Polyclinic at RSUD Dr. Adjidarmo Rangkasbitung. The data analysis technique was performed by entering data into tables and calculating the ratio between LDL and HDL for the group of patients at risk of heart disease based on the ratio obtained. The results of the study of the 30 respondents who were examined gave an overview of the results of the examination, with low risk LDL/HDL ratio values (low risk) of 21 people (70%); the average risk LDL/HDL ratio was 5 people (16.67%); the moderate risk LDL/HDL ratio was 1 person (3.3%); and the high risk LDL/HDL ratio was 3 people (10%). Patients who have a risk of developing coronary heart disease are 16 men (53.3%) and 14 women (46.7%). The average age of patients with coronary heart disease is over 50 in men and over 39 in women.
IDENTIFIKASI METALLO-β-LACTAMASE (MBL) PADA ISOLAT BAKTERI GRAM NEGATIF DI RUMAH SAKIT KOTA PALEMBANG Patricia, Venny; Yani, Ahmad
JPP JURNAL KESEHATAN POLTEKKES PALEMBANG Vol 18 No 1 (2023): JPP (Jurnal Kesehatan Poltekkes Palembang)
Publisher : Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jpp.v18i1.1424

Abstract

Latar Belakang: Resistensi antibiotik merupakan ancaman bagi efektifitas pencegahan dan pengobatan terhadap penyakit infeksi. Antibiotik beta laktam ditemukan pertama kali sampai sekarang, angka kejadian infeksi oleh bakteri penghasil ESBL semakin meningkat diseluruh dunia. Ada 3 kelas menurut klasifikasi Ambler, diantara nya kelas B yaitu metallo-beta-lactamase (MBL) paling banyak menyebar dan banyak didominasi oleh bakteri Enterobactericeae yang merupakan bagian dari bakteri gram negatif. mengetahui prevalensi enzim Metallo beta lactamase (MBL) pada isolat bakteri gram negatif berdasarkan metode fenotif dan genotif sehingga akan didapatkan data terkait resistensi antibiotik ESBL khususnya Metallo-ꞵ-Lactamase. Metode: Penelitian ini berupa studi laboratorik dengan survei klinis secara cross sectional. Konfirmasi fenotif menggunakan Double-disk synergy test (DDST) dan Combined disk synergy test (CDST) dan secara genotif dengan mendeteksi gen IMP, VIM dan NDM. Hasil: Total 88 isolat didapatkan hasil uji DDST positif sebanyak 44(50%) isolat dan CDST sebanyak 87(98.8%) isolat. Konfirmasi MBL secara genotif didapatkan positif hanya pada gen IMP 7(7.9%) isolat, sedangkan pada gen VIM dan NDM semuanya negatif. Data secara fenotif pada sampel yang positif gen IMP, didapatkan sebagai berikut yaitu DDST positif sebanyak 4(4.5%) dan CDST positif sebanyak 7(7.9%). Sensitifitas dari perbandingan dua metode tersebut diperoleh hasil sebanyak 51.1% dan Spesifisitas sebanyak 100%. bakteri terbanyak yaitu K.pneumonia 45(51,1%) dan E.coli 31(35,2%). Sampel terbanyak sputum 34(38,6%); pus 18(20,5%) serta urine 13(14,8%). Kesimpulan: Metode konfirmasi secara fenotif yang lebih mudah dipakai yaitu menggunakan metode CDST dan masih terdapat gen positif MBL pada isolate gram negatif. Kata kunci : Fenotif, Genotif, Gram negatif, MBL
PEMANFAATAN BEKATUL SEBAGAI BAHAN DASAR MEDIA ALTERNATIF PERTUMBUHAN Aspergillus flavus Oktaviani, Lu’lu Tsaniyah; Hamtini, Hamtini ,; Patricia, Venny; Armal, Hadits Lissentya
As-Syifaa Jurnal Farmasi Vol 16, No 2 (2024): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v16i2.1268

Abstract

Microbiology is the science that studies very small organisms, one of which is fungi. Fungi can grow and develop in a medium that contains sufficient nutrients. To identify the type of fungus, a growth medium is needed. Growth media is a substance consisting of a mixture of nutrients that support the growth of fungi, so it is necessary to make alternative media, one of which is using rice bran. The nutritional content of rice bran is 49.4 g carbohydrates, 24.7 g dietary fiber, 21.3 g fat, 16.5 g protein, 80 mg calcium, 2.1 grams phosphorus, 0.9 grams magnesium and 0.4 mg riboflavin vitamin. This research aims to determine the use of rice bran as a basic ingredient for alternative growth media for Aspergillus flavus. This type of research is an experiment by inoculating the Aspergillus flavus fungus using the Triple dot method. Observations were carried out for 7 days macroscopically by observing the diameter of the Aspergillus flavus fungus. The research results showed that there was an increase in colony diameter on rice bran media with concentrations of 8%, 10%, 12% and SDA media as a control of 29.3 mm, 33.0 mm, 33.8 mm and 34.9 mm. The effective concentration for the growth of the fungus Aspergillus flavus is a concentration of 12%. Based on the test results, it can be concluded that alternative media made from rice bran can be used as a growth medium for the fungus Aspergillus flavus.
Potensi Media Transport Modifikasi Sebagai Penunjang Pemeriksaan Kultur Bakteri Patricia, Venny; Yani, Ahmad; Nur fathonah, Amanda Kukuh
Jaringan Laboratorium Medis Vol 6, No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10574

Abstract

Bacterial culture sample transport is a critical point in the culture chain from sampling to final diagnosis. The ideal transport medium should be able to nurture the ability of bacteria to thrive coming from the sample without allowing them to grow. Transport media that already exist in Indonesia, namely in the form of powder, tend to be very expensive in price and transport media that can be used directly besides being expensive have a fast expiration period, which will increase the cost of treatment and services in hospitals, an innovation is needed by making alternative transport media from materials that are easily available around us that can be useful for taking samples. The purpose of this study is to see the potential of alternative transport media so that it can support diagnostics in bacterial culture. The study method uses an experimental laboratory with a true-experimental post-test-only design. In testing alternative transport media, sampling from diabetic foot ulcer patients using tofu pulp transport media (MTAT) and ICU swab beds with coconut charcoal transport media (MTAK). Samples of each media were taken, and as many as 20 samples were taken. In addition to treatment samples, each sample is confirmed using standard transport media as its control. This study obtained dominant bacteria from diabetic ulcer samples on alternative MTAT Citrobacter sp 6 (30%) and Control Citrobacter sp 8 (40%). Meanwhile, the ICU swab bed samples obtained dominant bacteria MTAK Bacillus sp 10 (50%) and Control 11 (55%). The conclusion of these two alternative transport media can be used as alternative transport media because they have the same growth results compared to standard media, and it can be ascertained that it is really bacteria that usually grow without contamination.
Post-Operative Glucose and HbA1c Levels in Patients Diagnosed with Cataract Nurmeily Rachmawati; Srimaya Winahyu; Ahmad Yani; Venny Patricia
Journal of Noncommunicable Diseases Prevention and Control Vol. 2 No. 1 (2024): Journal of Noncommunicable Diseases Prevention and Control
Publisher : Hypertension Prevention and Control Research Center, The Polytechnic of Health of Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61843/jondpac.v2i1.710

Abstract

Diabetes mellitus is known as a disease that continues to increase every year in the world. This disease can cause severe complications in several organs, including the heart, nerves, kidneys, eyes, and skin. One of the problems that arise in diabetes patients with complications in the eye area is cataracts. Cataract patients are generally treated by operating on the eye through light surgery. One way to evaluate the health status of postoperative cataract patients is by observing laboratory examination results, especially blood glucose and HbA1c parameters. This study aimed to determine the description of glucose and HbA1c levels in patients after cataract surgery. Respondents totaled 30 patients, with 17 and 13 women and men, respectively. The method used in this research is descriptive analysis with laboratory examination as the primary data source. Based on the results, most respondents were 60 years and under (60%). The results showed that 33.3% of respondents' postoperative glucose levels were above the normal limit (>150 mg/dL). Meanwhile, as many as 30% of respondents' postoperative HbA1c levels were above the normal limit (>6.5%). Based on gender, postoperative glucose and HbA1c levels, which are above normal, are dominated by men. Meanwhile, based on age, postoperative glucose and HbA1c levels above normal were dominated by the age group ≤60 years.
Uji Daya Hambat Ekstrak Daun Jamblang (Syzygium Cumini (L.) Skeels) Terhadap Pertumbuhan Bakteri Streptococcus Pyogenes dan Proteus Mirabilis Patricia, Venny; Zaini, Wawan Sofwan; Yani, Ahmad; Atikah, Siti
Jaringan Laboratorium Medis Vol. 3 No. 1 (2021): May 2021
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v3i1.7932

Abstract

Infectious diseases are a problem for public health and can increase patient morbidity and mortality. Bacteria that cause infectious diseases include Streptococcus pyogenes and Proteus mirabilis. Inappropriate use of antibiotics can cause resistance problems and the effects of undesirable drugs. Jamblang (Syzygium cumini) leaf extract can be used as a natural antibacterial drug. There is a study showing the content of active compounds in the leaves of Jamblang are Flavonoids, tannins, alkaloids, and saponins are components of chemical compounds that are suspected as antibacterial. This study aims to determine the antibacterial activity of Jamblang leaf extract against Streptococcus pyogenes and Proteus mirabilis bacteria. The method used is the Minimum Inhibitory Concentration method using well diffusion. The study used Jamblang leaf extract with various concentrations of 10%, 20%, 30%, and 40%, the test bacteria used were Streptococcus pyogenes and Proteus mirabilis, using positive control of chloramphenicol, and negative control of 10% DMSO. The results showed that Jamblang leaf extract can inhibit the growth of Streptococcus pyogenes and Proteus mirabilis bacteria in all concentrations. In the Kruskall Wallis Non-Parametric statistical test the two bacteria obtained P <0.05.In Streptococcus pyogenes bacteria the value of P = 0.031, and Proteus mirabilis bacteria the value of P = 0.015. These results indicate a real difference in this study.
Identifikasi Bakteri pada Luka Penderita Diabetes Melitus di Rumah Perawatan Luka Diabetes Patricia, Venny; Yani, Ahmad; Salsabila, Salwa; Isjworowati, Rr. Sri
Jaringan Laboratorium Medis Vol. 5 No. 1 (2023): May 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.8780

Abstract

Diabetes mellitus (DM) is a metabolic disease that occurs due to hyperglycemia. In Indonesia it self, DM has a relatively high prevalence, this is evidenced because Indonesia is in the category of the top 10 countries in the world. The type of research used is descriptive research, namely identifying bacteria and testing sensitivity on wounds of diabetics with diabetes mellitus by performing cultures that are examined macroscopically and microscopically with the number of respondents obtained by as many as 17 people in 4 weeks. The results of this study obtained the prevalence of the types of bacteria that are (82.35%) gram-negative and (17.65%) gram-positive. The gram negatives included Proteus mirabilis (17.65%), Proteus morgani (5.88%), Citrobacter diversus (23.54%), Pseudomonas aeruginosa (11.76%), Escherichia coli (5.88%), Enterobacter agglomerans (5.88%) and Enterobacter cloacae (11.76%). While the gram-positive include Staphylococcus aureus (17.65%) with antibiotic sensitivity results whose sensitivity is in the yellow zone, which is around 50-75%, namely ciprofloxacin and meropenem antibiotics are in the green zone, which is around 76-100%.