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All Journal Jurnal Kedokteran Brawijaya e-Journal Pustaka Kesehatan Jurnal Kesehatan STOMATOGNATIC- Jurnal Kedokteran Gigi Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) Journal of Dentomaxillofacial Science BIOEDUKASI Odonto dental journal
Happy Harmono
Bagian Biomedik, Fakultas Kedokteran Gigi, Universitas Jember, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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Journal : ODONTO Dental Journal

 1 
Evaluation of rat model oral candidiasis mucosal response immune Sulistyani, Erna; Triwahyuni, Iin Eliana; Harmono, Happy; Sholehah, Almaratus; Prameswari, Syefira Putri; Mayangsari, Zahra; Perwitasuci, Brigitta Damai; Wulandari, Widya Nurfitriastuti
Odonto : Dental Journal Vol 10, No 2 (2023): December 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.2.172-179

Abstract

Background: The choice of antifungal drugs is limited and has not yet made significant progress. The animal model of oral candidiasis is a crucial factor in exploring antifungals. In our previous study's oral candidiasis rat model, we found an increase in the sedimentation rate and a decrease in infection microbiologically and histologically on day 8 compared to day five after inoculation. On the other hand, blood plasma levels of IL-17, as the main cytokine in fungal infections, keep at a low level. The study aims to prove the increase in the immune response in the oral mucosa of an oral candidiasis rat model on the 8th day after inoculation of C. albicans. Methods: The sample consisted of 2 groups; healthy Wistar rats as a control and Wistar Rat rats treated as an oral candidiasis rat model. Eight days after inoculating C. albicans,The immune response was evaluated by counting the number of visual field inflammatory cells on the dorsum of the rat dorsum tongue.Results: The number of inflammatory cells, including macrophages in the dorsal tongue mucosa of oral candidiasis rats, was higher than that of healthy rats. Conclusion: There was an increase in the number of inflammatory cells in the dorsum of the tongue mucosa of the oral candidiasis rat model on day 8, which is a sign of an increased immune response in the experimental animal model.
Toothbrush design appropriate for pre-elderly: The relationship of toothbrush bristles number to oral hygiene Suhartini, Suhartini; Hamzah, Zahreni; Setyaningsih, Sari; Prijatmoko, Dwi; Harmono, Happy; Arina, Yuliana Mahdiyah Daat; Prihatiningrum, Berlian
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.%p

Abstract

Background: The increase in the elderly population leads to a decline in their health and affects the productivity and quality of life. Preventive measures must be taken to improve oral hygiene for the elderly starting from the pre-elderly group so that later it will form healthy and productive elderly. One of the efforts to improve dental hygiene and health is through mechanical tooth cleaning with a toothbrush. However, currently, there is no toothbrush design that is suitable for the condition of the pre-elderly oral cavity. Therefore, it is necessary to analyze the design of the number of toothbrush bristles as initial research to obtain an appropriate toothbrush design for the elderly. Method:The study was conducted on 30 participants using a toothbrush with a number of toothbrush bristles paths: with 4 paths, 3 paths, and 2 paths. The effectiveness of tooth brushing hygiene was measured through the debris index before using a toothbrush and after brushing. Result: The results of the Kruskal Wallis test showed a significance value of 0.01 (p
EFFECTIVENESS OF ROBUSTA COFFEE BEAN EXTRACT GEL ON COLLAGEN FIBERS DENSITY IN POST-GINGIVECTOMY WOUND HEALING Ermawati, Tantin; Harmono, Happy; Kartikasari, Dania
Odonto : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.8.1.45-53

Abstract

Background: Gingivectomy is a periodontal surgical procedure that eliminates excess gingival tissues by excision, usually to remove a gingival pocket which leads to scars and recontours the gingival to its proper anatomical form. Wound healing is a process to restore the missing functions and structures of a tissue due to injuries or inflammations. Robusta coffee bean contains many bioactive compounds that can accelerate the wound healing process. The study aimed to determinate the effectiveness of robusta coffee bean extract gel with concentration 40%,50%,60% on collagen fibers density in post-gingivectomy wound healing Method: 36 Wistar rats were divided into 9 groups: control, gingivectomy without therapy, gingivectomy +40% robusta coffee bean extract gel, gingivectomy +50% robusta coffee bean extract gel, and gingivectomy+60% robusta coffee bean extract gel. The last 4 groups were divided again into day 3 and 7 euthanasia. The results were processed by Trichrome Mallory to visualized the collagen fibers and then measured by ImageJ software.Result: Robusta coffee beans extract gel therapy with concentration 40%, 50% and 60% had higher average collagen fibers density compared to group without therapy.Conclusion: Robusta coffee bean extract gel increased the density of collagen fibers in post-gingivectomy wound healing
Co-Authors Ainunnusak Ayuningtyas Anisa Nur Hakima Arina, Yuliana Mahdiyah Daat Cicik Khilar Rizqi Desi Sandra Sari Didin Erma Indahyani Dina Nuur Rosyiidah Dwi Prijatmoko Erna Sulistyani Fany, Manta Fawwazi, Rafif Hanif Hakima, Anisa Nur Herniyati Herniyati Herniyati Hestieyonini Hadnyanawati I Dewa Ayu Ratna Dewanti I Dewa Ayu Susilawati IDA Susilawati Iin Eliana Triwahyuni Kartikasari, Dania Leliana Sabdra deviade Putri Leliana Sandra Devi Ade Putri Lisa Miftakhul Janna Maria Devitha Masari, Al Mayangsari, Zahra Melok Aris Wahyukundari Melok Aris Wahyukundari, Melok Aris Morauli, Fatricia Muchamad Ziyad Afif Nahdiya Fitriyana Nailah Rahmadani Nailufar, Khanun Perwitasuci, Brigitta Damai Prameswari, Syefira Putri Prasetya, Rendra C. Prihatiningrum, Berlian Pudjiastuti, Peni Pujiana Endah Lestari Qurratul Aini Wahyu Pratiwi Raditya Nugroho Riclas Yusuf Punta Wibisono Saikha Adila Azzah Sari Setyaningsih Setyaningsih, Sari Sholehah, Almaratus Sri Hernawati Suhartini Suhartini Tantin Ermawati Tantin Ermawati Utha, Maria Fransisca Wanodyo, Ari Tri Wulandari, Widya Nurfitriastuti Yuliana Mahdiyah Daat Arina Zahara Meilawaty Zahara Meilawaty Zahreni Hamzah