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All Journal E-Jurnal Medika Udayana Jurnal Kedokteran Diponegoro WMJ (Warmadewa Medical Journal) Molecular and Cellular Biomedical Sciences (MCBS) J-Dinamika: Jurnal Pengabdian Kepada Masyarakat INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Pengabdian Masyarakat (ABDIRA) Indonesian Journal of Cancer Makara Journal of Science Ahmad Dahlan Medical Journal Folia Medica Indonesiana Jurnal Implementa Husada (JIH)
Putri, Rachma Greta Perdana
Department Of Histology, Faculty Of Medicine, Universitas Ahmad Dahlan, Yogyakarta, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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The Effect of Education using Comics on the Knowledge of Earthquake Mitigation of 4th Grade Students at Al-Azhar 16 Islamic Elementary School Cilacap Reza, Anggit; Wijaya, Oktomi; Qomariyah, Nurul; Hutomo, Muhammad Agita; Khoiru Nisa, Afifah; Ulfa, MH Muflihatul; Perdana Putri, Rachma Greta
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v5i1.10831

Abstract

Indonesia is an archipelagic country situated on the Ring of Fire, which frequently experiences earthquakes. Cilacap Regency is ranked 456th nationally with a medium-risk classification in the Earthquake Disaster Risk Index for the year 2021. The impact of earthquakes depends on their type and magnitude, including on schools, with 52,902 schools located in earthquake-prone areas. During the 2018 NTB Earthquake, 1,235 schools experienced damage. Earthquakes can also occur while children are studying at school. Elementary schools are one of the foundations of the children's community. The group of elementary school children is a vulnerable group that needs protection and, at the same time, needs to enhance their knowledge of earthquake disaster mitigation. One enjoyable medium to educate elementary school children about earthquake disaster mitigation is through comics.To determine the influence of Education with Comic Media on the Knowledge of Earthquake Disaster Mitigation for 4th-grade students at SD Islam Al-Azhar 16 Cilacap, a research was conducted using a qualitative research method with a Pre Experimental design using the One Group Pretest-Posttest design. The sampling technique used in this study was total sampling, so all 78 members of the population were included as samples.Statistical analysis using the Wilcoxon signed-rank test showed a Z-value of -6.941 and a significance value (p-value) of 0.000, at α = 0.05. This means that there is a significant difference in the average knowledge between before and after providing Education with Comic Media for Earthquake Disaster Mitigation.
Pengenalan Makanan Halal dan Sehat Bagi Putra/Putri dari Pelajar dan Pekerja Migran di Lingkungan PCIA Taiwan: Making Halal-Healthy Food, Fun For Kids Septian Emma Dwi; Putri, Rachma Greta Perdana; Dewinta, Mustika Cahya Nirmala
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 9 No 2 (2024): Agustus
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/j-dinamika.v9i2.5024

Abstract

Perbedaan pola dan kebiasaan makan merupakan salah satu shock culture yang dihadapi oleh keluarga yang berpindah ke luar negeri untuk sekolah ataupun bekerja. Hal ini terjadi termasuk pada anak-anak yang mengikuti orangtuanya pindah ke luar negeri. Proses akulturasi pola makan yang dialami anak-anak tersebut dapat menyebabkan risiko obesitas dan penyakit kronis. Hal ini karena dipengaruhi perubahan fisik dan lingkungan baru. Disisi lain, kesibukan orangtua, juga bisa mempengaruhi keseimbangan asupan nutrisi makanan pada anak. Oleh karena itu, tim mengusulkan kegiatan pengabdian dengan tema pengenalan makanan sehat bagi anak-anak pelajar/pekerja migran di lingkungan PCIA Taiwan. Pelaksanaan kegiatan pengabdian dilakukan pada tanggal 1-2 Februari 2024 di Al-Hadi Taiwan Islamic Education & Culture Center, New Taipei City dengan sasaran anak-anak. Kegiatan berikutnya dilaksanakan secara online pada tanggal 7 Juni 2024 dengan sasaran para orangtua. Materi yang disampaikan dalam kegiatan ini meliputi pengenalan makanan sehat dan halal, adab makan dan minum dalam ajaran Islam, gangguan kesehatan yang berkaitan dengan makanan dan pencegahannya, peran orangtua dalam menghadapi shock culture perbedaan pola dan kebiasaan makan pada anak, dan praktik membuat makanan sehat dan memilih makanan halal.
Functional Disaster Preparedness at Community Health Centers in Mount Merapi Yogyakarta Disaster Prone Areas Arliono, Tri Yunanto; Putra, Fadly Muhammad Bima; Wijaya, Oktomi; Ihsana, Nuni; Indarto, Bayu Praditya; Hutomo, Muhammad Agita; Putri, Rachma Greta Perdana; Heriyanto, Mochammad Junaidy; Wijaya, Adi Indra; Alim, Ahmad Muttaqin
Ahmad Dahlan Medical Journal Vol. 5 No. 2 (2024): November 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v5i2.10946

Abstract

Mount Merapi is one of the most active volcanoes in the world. The major eruptions happened in 1768, 1822, 1849, 1872, and the most recently in 2010. Three health centers are situated at the foot of Mount Merapi, with a high risk of potential disasters, ranging from eruptions and cold lava flows to landslides. To maintain service quality and effective disaster response, this study aimed to provide evaluation material for optimizing service quality and assessing the readiness level of these health centers. The research used a quantitative analysis method, collecting numerical data to outline the preparedness level of the three health centers: Puskesmas Pakem, Puskesmas Turi, and Puskesmas Cangkringan. The results, achieved through manual calculations, indicated that Puskesmas Pakem exhibited the highest functional preparedness with a score of 0.45, categorized as "moderate." Puskesmas Turi scored 0.40, also categorized as "moderate." On the other hand, Puskesmas Cangkringan scored 0.24, falling into the "low" category. In conclusion, two health centers fell into the "moderate" category, which means the risks to the safety of staff and patients persisted, necessitating future interventions. Meanwhile, one health center fell into the "low" category, signifying its inability to function optimally during disasters and requiring immediate interventions
Network Pharmacology and Molecular Docking Analysis of Nephelium lappaceum (Rambutan) Compounds as Potential Alternative Treatments for Lung Cancer Utami, Dwi; Farid, Muhammad; Putri, Rachma Greta Perdana
Makara Journal of Science Vol. 29, No. 3
Publisher : UI Scholars Hub

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Abstract

Introduction: Lung cancer is characterized by high mortality rates and poor prognosis, further requiring alternative therapies owing to the adverse effects of conventional chemotherapy. Rambutan (Nephelium lappaceum L.) has antimicrobial, antiproliferative, and antioxidant properties and can cure cancer. Method: Compounds from rambutan peel were identified through PubChem and analyzed for physicochemical properties using SwissADME. Target proteins were identified using SuperPred and compared with lung cancer–related proteins from GeneCards via Venny. Protein interactions were examined and visualized using STRING and Cytoscape, respectively. Protein activity was analyzed using WebGestalt, and docking simulations were performed using Autodock 4.2.6. Result: Physicochemical analysis of 10 active rambutan compounds via SwissADME showed favorable properties based on Lipinski’s rule, suggesting good oral bioavailability. In total, 276 specific target proteins were related to lung cancer. Cytoscape visualized the 53 core proteins implicated in lung cancer. Gene ontology and Kyoto Encyclopedia of Genes and Genomes analyses indicated that rambutan compounds are active in lung cancer pathways, particularly nonsmall cell lung cancer. The analysis identified the top 10 interacting proteins STAT3 and CASP3 had the highest interaction value of 28, followed by PIK3CA and NFKB1 at 22, MAPK3, PIK3R1, PTGS2, GRB2, MAPK1, and CASP8. Per docking simulations, 1,2-diphenylethane-1-ol was the highest affinity to STAT3 (−4.78) and CASP3 (−6.75). Conclusion: Rambutan peel compounds have remarkable anticancer potential, particularly with high affinity for STAT3 and CASP3 proteins, based on in silico molecular docking studies.
Association Between Obesity and the Incidence of Hypertension Among Adolescents in Ponorogo Ulfa, MH Muflihatul; Greta Perdana Putri,, Rachma; Fadhila, Rais
Ahmad Dahlan Medical Journal Vol. 6 No. 2 (2025): November 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v6i2.14308

Abstract

Obesity occurs due to excess energy stored in body fat tissue, resulting from an imbalance between energy intake and expenditure. In adolescence, obesity is a multifactorial health problem influenced by genetic, behavioral, environmental, and social factors, and is a known risk factor for hypertension. The pathogenesis of hypertension in obese individuals involves abnormal adipose tissue activity in producing hormones and adipokines, although the mechanisms are not yet fully understood. Several studies have linked obesity to hypertension, but mostly in adult populations, where the indicators for obesity differ from those for adolescents and children. In younger populations, overweight or obesity assessment should be based on BMI-for-age charts adjusted for sex, yet studies in adolescents often still use adult criteria. This study aimed to determine the association between obesity and hypertension among adolescents in Ponorogo. An observational analytic study with a cross-sectional design was conducted using data from the 2024 PASHMINA (Pelayanan Kesehatan Remaja Milik NA) health screening program organized by Regional Board of Nasyiatul Aisyiyah of Ponorogo among senior high school students. A total of 179 respondents participated, with 65.9% female and 65.4% having normal nutritional status. The overall prevalence of hypertension was 6.1%, while obesity prevalence was 12.8%. Hypertension was more common in obese adolescents (26.1%) compared to non-obese adolescents (3.2%), with obesity increasing the risk of hypertension by 10.66 times (p < 0.001). These findings highlight the need for appropriate obesity assessment methods in adolescents and the importance of nutrition education, promotion of physical activity, early detection, and regular health monitoring to prevent hypertension from an early age.
COMPARISON OF INTRAPERITONEAL AND INTRADUCTAL ROUTES IN THE GROWTH OF N-METHYL-N-NITROSOUREA-INDUCED BREAST CANCER IN SPRAGUE DAWLEY RATS: A SYSTEMATIC REVIEW 2014–2024 Prameswari, Adilla Soraya; Sompokan, Ruendhita Azzahra Sari; Annisa, Annisa; Putri, Rachma Greta Perdana; Yuniasih, Dewi; Danian, Muhamad; Tianotak, Muhammad Tri Yoga
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Breast cancer is one of the[-6pc]AU: Please provide affiliations for your paper. leading causes of death for women worldwide, characterized by malignant tumors in the mammary epithelium. Breast cancer modelling using Sprague Dawley animals induced by N-Methyl-N-Nitrosourea (MNU) compounds is commonly used through various administration routes. The intraperitoneal route is the conventional route and the intraductal route is a new route capable of directly targeting the mammary ducts. Both routes affect the speed and characteristics of breast cancer cells in experimental animals. This systematic review using PubMed and Scopus databases from 2014-2024 aims to compare the effects of intraperitoneal and intraductal administration routes on breast cancer induction and the similarities in histopathological characteristics and biomarkers with human breast cancer cells. Of the 324 articles, 15 met the inclusion criteria showing that the intraductal route induces tumors faster (6–8 weeks) with Ductal Carcinoma In Situ (DCIS) type, ER+/PgR+ expression, and low Ki-67 index, resembling the luminal A subtype. The intraperitoneal route requires 8–12 weeks, producing multiple tumors with a high Ki-67 index, resembling luminal B. Administration of additional substances such as PF4, white tea, and physical activity are anti-tumorigenic, while radiation and a high-fat diet are pro-tumorigenic. Therefore, the intraductal route can be used as the main choice in selecting the route of administration of MNU induction.
The Association Between Exclusive Breastfeeding and the Occurrence of Stunting Among Children Aged 12-60 Months in Community Health Centers in Yogyakarta City Eureka Raihan Asqy Dendy; Rachma Greta Perdana Putri; Dewi Yuniasih; Nurcholid Umam Kurniawan
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 1 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i1.40723

Abstract

Background: Stunting is a condition of chronic malnutrition caused by suboptimal nutritional intake due to prolonged inadequate food consumption. Stunting, also known as being short, indicates a growth failure that occurs both before and after birth. The categorization of stunting based on the World Health Organization's (WHO) standard growth reference is a deficit in length or height for age with a Z-score < -2. Symptoms of stunting usually appear after the golden period of growth (2 years old). One of the contributing factors to stunting in toddlers is an imbalanced food intake. Exclusive breastfeeding is a critical component of nutritional intake to support a child's good nutritional status. It may contribute to the prevalence of stunting.Methods: This is a quantitative study with a cross-sectional research design. The data collection consists of secondary data from stunting medical record records. The inclusion criteria of the study are children aged 12-60 months with complete data of anthropometric. Exclusion criteria are endocrine disorder, skeletal abnormalities, dysmorphic disorder, chronic disease, history of familial short stature, and constitutional delay of growth and puberty. Analysis of the data using Chi-square.Results: There is a relationship between exclusive breastfeeding and the occurrence of stunting in children aged 12-60 months at the Community Health Centre in Yogyakarta City with a p-value of 0.00 (p < 0.05).Conclusion: There is a correlation between exclusive breastfeeding and the occurrence of stunting among children aged 12-60 months in primary healthcare care in Yogyakarta City.
The Association Between Hypertension and Stroke in PKU Muhammadiyah Gamping Hospital Intan Dyah Prawesti; Andrianto Selohandono; Ario Tejosukmono; Novi Wijayanti Sukirto; Rachma Greta Perdana Putri
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 6 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i6.46464

Abstract

Background: Stroke is a non-communicable disease whose annual incidence or prevalence continues to increase, with one of the causes being hypertension. Hypertension is a condition of increased blood pressure, if not controlled, can lead to complications. The incidence of stroke in Sleman Regency reaches 10,4% and the incidence of hypertension in Sleman Regency reaches 23,7%.Objective: This research aims to determine the relationship between patients who have hypertension with the occurrence of stroke.Methods: This research is a quantitative analytic study using a cross-sectional design. The population is all stroke patients at PKU Muhammadiyah Gamping Hospital, with a sample of 99 patients and the data collection technique used is purposive sampling. The research data was taken using medical records.Results: The result showed that the majority of patients had hemorrhagic stroke (62,6%) with grade 3 hypertension (37,3%). The odds ratio (OR) for hypertension grade 3 has a risk of 7,153 times having a stroke compared to grade 1 hypertension. The p-value for hypertension 1 and hypertension 3 is 0,001 (p<0,005) which indicates a significant relationship between higher grade hypertension and the incidence of hemorrhagic stroke. Conclusion: There is a relationship between higher grade hypertension and the incidence of hemorrhagic stroke
ANALYSIS OF FAMILY SUPPORT FOR MEDICATION COMPLIANCE IN HYPERTENSIVE PATIENTS PARTICIPATING PROLANIS AT PUSKESMAS TEPUS 2 Maulana Faris Ikhzul Haq; Rachma Greta Perdana Putri; Tira Alfiani Laariya; Leonny Dwi Rizkita
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 14, No 4 (2025): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkd (dmj).v14i4.49421

Abstract

Introduction: The Indonesian Ministry of Health has released a list of the most diagnosed non-communicable diseases in 2023, and hypertension, or high blood pressure, was in the first position. One of the risk factors that cause an increase in the incidence of hypertension is patient non-compliance in implementing the therapy program. Family support is one of the factors that has a significant contribution as a patient booster in influencing patient compliance. The family has an important role in the process of supervision, maintenance, and prevention of hypertension complications. Methods: This study is a quantitative study with a cross-sectional approach. Sampling was carried out using the total sampling technique at Tepus 2 Puskesmas. The total is 43 hypertensive patients participating in Prolanis. Data collection was carried out by distributing family support questionnaires and Morisky Medication Compliance Scale (MMAS-8) questionnaires. Bivariate tests were performed using Chi Square and Spearman's rho tests. Results: Univariate results showed that most respondents had sufficient family support, as many as 28 people (65.1%), and a high level of compliance with taking medication, as many as 25 people (58.1%). From the bivariate results obtained, a p-value of 0.001 (p < 0.05) and an r-value of 0.478. Conclusion: There is a relationship between family support and adherence to medication compliance in hypertensive patients participating in Prolanis at Tepus 2 Puskesmas in 2023 with sufficient relationship strength and positive correlation (unidirectional); the better the family support.
COMPARISON OF PAIN PERCEPTION IN CATARACT SURGERY WITH PHACO- HORIZONTAL-CHOP TECHNIQUE VERSUS VERTICAL-CHOP TECHNIQUE IN GRADE 3 CATARACT Imam Masduki; Emelia, Dwi Ditha; Putri, Rachma Greta Perdana
Ahmad Dahlan Medical Journal Vol. 7 No. 1 (2026): May 2026
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v7i1.14565

Abstract

Most cataract surgery is done by phacoemulsification method. Phacoemulsification cataract surgery with horizontal chop and vertical chop techniques is quite effective until now. In cataract surgery, generally used topical anesthetic pantocaine 0.5% (tetracaine 0.5%) to control pain in patients. This research aims to compare pain perception using a numeric rating scale in grade 3 cataracts operated by the phaco-horizontal-chop versus vertical-chop technique. This study is a comparative analytical study with a total of 87 subjects, consisting of 45 subjects undergoing surgery with the horizontal-chop technique, and 43 subjects with the vertical-chop technique. All patients were given the same topical anesthetic, pantocaine 0,5%. After the operation done, each subject will be asked about their pain perception using a numerical rating scale parameter. Then, the data were analyzed using univariate and bivariate analysis using chi-square. Among the 87 patients, mean pain scale in this study was 3.51, with a median value of 3.00. The minimum value of the pain scale was 1 while the maximum value was 6. The results showed that there was no significant relationship to pain experienced by patients undergoing phacoemulsification cataract surgery with the horizontal-chop technique compared with the vertical-chop (p = 1,000).
Co-Authors Alim, Ahmad Muttaqin Amanatus Sholikhah Andrianto Selohandono Annisa Annisa Annisa Annisa Ario Tejosukmono Ario Tejosukmono Ario Tejosukmono Arliono, Tri Yunanto Asarizq Fatihah Rasjava Danarto Danarto Danarto Danarto Danian, Muhamad Dewi Yuniasih Dewi Yuniasih Dewi Yuniasih Dewinta, Mustika Cahya Nirmala Didik Setyo Heriyanto Dwi Utami Emelia, Dwi Ditha Eureka Raihan Asqy Dendy Fadhila, Rais Fardhiasih Dwi Astuti Heriyanto, Mochammad Junaidy Hutomo, Muhammad Agita Ihsana, Nuni Imam Masduki Indarto, Bayu Praditya Indwiani Astuti Indwiani Astuti Intan Dyah Prawesti Irfan Rahmatullah Katrina Rizky Salsabila Khoiru Nisa, Afifah Leonny Dwi Rizkita Leonny Dwi Rizkita Maulana Faris Ikhzul Haq Moch. Junaidy Heriyanto Muhammad Agita Hutomo Muhammad Farid Muhammad Faris Nafiuzzaqi murdiyanto, joko Novi Wijayanti Sukirto Nur Arfian Nurcholid Umam Kurniawan Nurul Qomariyah Oktomi Wijaya Pamungkasih, Wahyu Prameswari, Adilla Soraya Prisilla Maya Heni Pratiwi Purwanto, Barkah Djaka Putra, Fadly Muhammad Bima Putri Dangga, Vathana Az Zahra Rahmatullah, Irfan Reza, Anggit Rokhmah, Budi Nur Rosyida Awalia Safitri Sari Eka Pratiwi Septian Emma Dwi Shafa Zahra Salsabila Sofia Mubarika Haryana Solikhah Solikhah Sompokan, Ruendhita Azzahra Sari Sri Nuryani Wahyuningrum Sri Nuryani Wahyuningrum Sukirto, Novi Wijayanti Tianotak, Muhammad Tri Yoga Tiara Ismirahmadani Tira Alfiani Laariya Ulfa, MH Muflihatul Wijaya, Adi Indra Wildan Fandi Farihan Yuni Herliyanti Yuniasih, Dewi