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P3A0 Perdarahan Pasca Persalinan Pervaginam et causa Atonia Uteri: Laporan Kasus Alandra Rizhaqi Vastra; Ikhlas Taufik; Nurul Islamy
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.809

Abstract

Postpartum haemorrhage is a state of blood loss >500 ml through vaginal delivery, or >1000 ml in caesarean section after delivery. One of the most common causes of postpartum hemorrhage is uterine atony. Uterine atony is a condition of weak uterine tone that causes the uterus to be unable to close the bleeding from the placental implantation site after the baby and placenta are born. Mrs. RF, 36 years old, came to the ER of RS Abdul Moeleok with postpartum bleeding since ± 2 hours before entering the hospital. The patient gave birth vaginally with the help of a midwife and experienced postpartum bleeding due to the absence of adequate uterine contractions (uterine atony) after delivery. The patient was treated with oxytocin and misprostol and the bleeding was resolved.
GAMBARAN PENGETAHUAN MAHASISWA FAKULTAS KEDOKTERAN PROGRAM STUDI PENDIDIKAN DOKTER UNIVERSITAS LAMPUNG ANGKATAN 2021 TERHADAP ANESTESI DAN PERAN DOKTER SPESIALIS ANESTESI Javinka Fairuz Zahrani; Liana Sidharti; Nurul Islamy; Bambang Eko Subakti
Medula Vol 13 No 7 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i7.849

Abstract

Anesthesia is an action in the medical field that is carried out intentionally on healthy patients and patients who have a disease from mild to severe with the aim that the patient does not feel sick when surgery is performed. This study aims to describe the knowledge of students of the Faculty of Medicine, Medical Education Study Program, University of Lampung on anesthesia and the role of anesthesiologists. This study used a descriptive cross-sectional research method on 136 samples selected through simple random sampling technique. The study used a questionnaire given via google form. The data were analyzed univariately to describe the knowledge of students of the medical faculty of the Lampung University medical education study program on anesthesia and the role of anesthesiologists. The results showed that 12 respondents (8.8%) had good knowledge, 54 respondents (39.7%) had sufficient knowledge, and 70 respondents (51.5%) had less knowledge about anesthesia and the role of anesthesiologists. . The conclusion in this study was that students of the medical faculty of the Lampung University medical education study program class of 2021 still lacked knowledge about anesthesia and the role of anesthesiologists.
Laporan Kasus: Burst Abdomen Paska Operasi Laparatomi Kista Ovarium 2 Bulan Lalu (Di RS Luar) Rezita Rahma Reza Rezita Rahma Reza; Nurul Islamy
MAJORITY Vol 10 No 2 (2021): MAJORITY
Publisher : Majority

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Abstract

Burst abdomen is a postoperative complication that involves tissue damage at the surgical incision site where there is separation due to suture removal that occurs in the surgical wound before the wound healing process is complete. The distended abdomen is part of the complete type of abdominal dehiscence wound. The risk factors for burst abdomen can be classified into three groups, namely pre-operative risk factors, intra-operative risk factors, and post-operative risk factors. This study is a case report at RSUD Abdul Moeloek Bandar Lampung. It is reported that a 48-year-old woman came with complaints of abdominal pain due to open stitches since 1 week ago, after undergoing laparotomy for ovarian cysts 2 months ago at an external hospital. Abdominal pain occurs around the open surgical wound about 8 cm x 1cm x 4cm with pus and blood. The risk factors obtained in the patient were pre-operative risk factors in the form of a history of diabetes mellitus and anemia. The patient was treated in the form of a re-closure operation with the Smead Jones Suture suture technique.
Faktor-faktor yang Mempengaruhi Prolaps Organ Panggul di RSUD DR. H. Abdul Moeloek Provinsi Lampung Periode 1 Januari 2014 – 31 Desember 2018 Fiana Deswita; Ratna Dewi Puspita Sari; Ety Apriliana; Nurul Islamy
MAJORITY Vol 10 No 2 (2021): MAJORITY
Publisher : Majority

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Abstract

Pelvic organ prolapse (POP) is a condition that affects a woman's quality of life. Pelvic organ prolapse can include uterine prolapse, cystocele and rectocele. POP occurs due to weakness of the muscles, ligaments and fascia that support the pelvic organs. This condition can be influenced by factors such as age, parity, menopause, body mass index and occupation. This study aims to determine the relationship of these factors to the incidence of POP. The study is an observational analytic with cross sectional approach, using secondary data from the medical records of gynecological patients at H. Abdul Moeloek Hospital in the period 1 January 2014 to 31 December 2018 with a total sampling technique. Then univariate and bivariate analyzes were performed using the chi-square test. The incidence of POP in the period of 1 January 2014 to 31 December 2018 in the H. Abdul Moeloek Hospital was 33 cases. Factors that had a relationship with the highest risk sequence are parity (p = 0.000; OR 7,959), age (p = 0.002; OR 7,250), menopause (p = 0.014; OR 5.019), body mass index (p = 0.036; OR 3.297) and type of work (p = 0.036; OR 3.297).All factors studied is parity, age, menopause, body mass index and type of work were associated with the incidence of pelvic organ prolapse in patients at H. Abdul Moeloek Hospital, Lampung Province January 2014 to 31 December 2018
GAMBARAN FOTO RONTGEN TORAKS PENDERITA HIV/AIDS DAN TB PARU Mahardika Putra; Waluyo Rudiyanto; Nurul Islamy; M. Ricky Ramadhian
MAJORITY Vol 11 No 2 (2023): MAJORITY
Publisher : Majority

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Abstract

The high morbidity rate caused by infection with the Human Immunodeficiency Virus (HIV) makes many people more susceptible to infection by viruses, fungi or bacteria. One of the co-infections that most often affects people with HIV/AIDS (PLWHA), namely pulmonary TB. based on data from the Lampung provincial health office, the city of Bandar Lampung is ranked first with the number of HIV and pulmonary TB of 1480 cases. Investigations for cases of PLWHA with pulmonary TB are very diverse, one of which is a chest X-ray examination. Chest X-ray examination is known to be easier to find the location of the lesion from tuberculosis and also on the chest X-ray picture usually there are signs that someone has pulmonary TB infection even though there are no symptoms yet. This study used a univariate descriptive research method, the sample of this study was 65 people in RSUD DR. H. ABDUL MOELOEK was taken using the total sampling method. Based on the results of the analysis, the results obtained from 65 samples showed that for the age most people with HIV/AIDS and pulmonary TB were in the age range of 31-40 years as much as 35.4%, then for sex most affected were men as much as 83.1%, based on the shape of the lesion, the most affected were typical lesions 67.7%, for based on the location of the lesion the most patients had lesions in 1 and 2 lobes only in the lung field as much as 27.7%, and for the area of the lesion in HIV/AIDS and pulmonary TB patients the most affected by extensive lesions as much as 40%.
Penggunaan Tanaman Mangrove Sebagai Obat Herbal di Lampung Selatan Rodiani, Rodiani; Islamy, Nurul
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1085

Abstract

As a means of adaptation to extreme habitats, mangrove plants produce a variety of secondary metabolic substances that have the potential as herbal medicines. Empirically, coastal communities have utilized and proven the medicinal properties of mangrove plants. The study’s objective was to determine the use of mangrove plants as herbal medicine in Pematang Pasir, South Lampung. The use of mangroves as medicine was obtained through in-depth interviews followed by descriptive analysis and calculation of species use value, plant part value, and fidelity level. The results showed that the use of mangrove plants as herbal medicine in the Pematang Pasir area, Ketapang District, South Lampung, ethnically dominated by the Serang ethnic group (54%), with the majority having completed junior high school education (38.1%), economically classified as middle-income based on BPS criteria (2020), with the majority working as fishermen and farmers, and the majority being adults (over 40 years old). Based on the Species Use Value (SUV), R. apiculata is the most popular and widely used species by the community. Based on Plant Part Value (PPV) analysis, leaves are the most commonly used part as herbal medicine, with over 75% of the population using mangrove leaves as a source of treatment, while other parts are less utilized. The level of community trust in the benefits of mangrove plants as medicine is relatively low, with figures below 50%. Rhizophora apiculata is the only species accepted with a high level of confidence of 88%, particularly as a wound or antiseptic medicine.
Breast Cancer Metastases Based on Molecular Subtypes at RSUD Dr. H. Abdul Moeloek Lampung Nurmayeni; Islamy, Nurul; Tjiptaningrum, Agustyas; Siregar, Bintang Abadi; Kusumaningtyas, Aditya; Windarti, Indri
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.904

Abstract

BACKGROUND:Breast cancer is the most common cancer in Indonesia and is a leading cause of cancer-related deaths in the country. Metastases are responsible for most deaths among breast cancer patients. Breast cancer is typically classified into four subtypes based on immunohistochemistry: luminal A, luminal B, HER2+, and TNBC. OBJECTIVE:To determine the association between the metastatic pattern of breast cancer and their molecular subtypes at RSUD Dr. H. Abdul Moeloek Lampung. METHOD:This study was an observational analytic study with a cross-sectional design. The sample comprised 81 individuals who had suffered from breast cancer and were recorded in the medical records section of RSUD Dr. H. Abdul Moeloek Lampung between 2013 – 2021 and met the inclusion and exclusion criteria. The association between breast cancer subtypes and the incidence and metastase sites were tested using the Chi-Square test. RESULT:This study found a significant association between breast cancer subtypes and the incidence of metastases (p <0.05). The TNBC subtype had a more frequent rate of metastases (34.5%) than the other subtypes (31% luminal B, 20.7% luminal A, and HER2+ 13.8%). The study also revealed a relationship between ER status and the incidence of metastases (p < 0.05). The luminal A subtype tends to metastasize to the liver, luminal B tends to metastasize to the bone, HER2+ tends to metastasize to the lung and liver, and TNBC tends to metastasize to the lung. However, no significant association was found between breast cancer subtypes and metastatic sites. CONCLUSION:There was a significant association between breast cancer subtypes and the incidence of metastases, but not with the metastatic sites.  
Sepsis and Septic Shock in Pregnancy Islamy, Nurul; Aziz, M. Alamsyah; Yonata, Ade; Lumentut, Anastasia M.; Maelissa, Merlin M.; Khaerunnisa P, Maya; Wirawan, Wahyudi
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1863

Abstract

Sepsis during pregnancy is a critical condition that leads to organ dysfunction due to an abnormal response to infection. It remains a significant cause of maternal morbidity and mortality worldwide. The World Health Organization (WHO) reports a global prevalence of 4.4% of live births affected by maternal sepsis, with varying incidences across countries. Sepsis ranks among the top five causes of maternal deaths globally, contributing to 12.7% of pregnancy-related mortality in the United States. The physiological changes during pregnancy, such as increased blood volume and immune response modulation, create conditions that make pregnant individuals more susceptible to infections, complicating the timely diagnosis of sepsis. Due to these physiological differences, common sepsis screening tools like qSOFA and SOFA are often inadequate in pregnant patients, highlighting the need for specialized diagnostic and management strategies. Early detection and timely treatment are essential to improving maternal outcomes. Several screening tools, such as the Maternal Early Warning Trigger (MEWT) tool, have been designed to aid in the early identification of deteriorating maternal health. Once sepsis is suspected, prompt antibiotic therapy, fluid resuscitation, and vasopressor support are critical to prevent progression to septic shock. Additionally, controlling the infection source through surgical intervention or drainage may be necessary. Despite advances in sepsis management, challenges remain, particularly in identifying and treating sepsis in pregnant patients due to overlapping symptoms with normal pregnancy changes. Therefore, early recognition and appropriate intervention are key to reducing the impact of sepsis during pregnancy.
Tuberculosis in Pregnancy Lumentut, Anastasia Mariane; Tendean, Hermie; Najoan, Rizki; Islamy, Nurul; Khaerunnisa, Maya; Wirawan, Wahyudi; Maelissa, Merlin
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1870

Abstract

Tuberculosis (TB) during pregnancy presents significant risks to both the mother and fetus, including complications such as abortion, preterm birth, low birth weight, and postpartum hemorrhage. The immune changes in pregnancy, particularly the shift in TH1/TH2 balance, increase the risk of latent TB reactivation. Diagnosing TB in pregnant women is challenging due to overlapping symptoms with normal pregnancy changes. However, early diagnosis is crucial for effective management, with molecular tests offering assistance, although bacterial culture remains the gold standard. High-risk pregnant women include those with close contact with active TB patients, HIV, immunosuppressive conditions, or severe immunocompromised states such as lymphoma, leukemia, or organ transplant recipients. These women should undergo sputum testing for acid-fast bacilli smear, mycobacterial culture, and nucleic acid amplification testing if TB is suspected. Immunosuppressed patients may require further testing, even if interferon-gamma release assays or tuberculin skin tests are negative. Retesting is recommended eight weeks after exposure to infectious TB. The management of TB in pregnancy involves a multidisciplinary approach, including obstetricians, infectious disease specialists, and neonatologists. First-line anti-TB medications are safe during pregnancy and help prevent maternal and perinatal complications. Treatment for latent TB infection (LTBI) is generally delayed until after delivery. Breastfeeding is safe for mothers on first-line anti-TB medications, as drug levels in breast milk are too low to harm the infant. Early diagnosis, prompt treatment, and proper care are essential to reduce TB-related risks during pregnancy.
Folate Metabolism and Its Implications in Pregnancy Puspitasari, Maya Khaerunnisa; Irianti, Setyorini; Pramatirta, Akhmad Yogi; Wirawan, Wahyudi; Islamy, Nurul; Maelissa, Merlin Margreth; Lumentut, Anastasia Mariane
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1885

Abstract

The impact of folate nutritional status on a variety of pregnancy outcomes has been acknowledged for a considerable period of time. Folate is increasingly recognized not just as a nutrient required to prevent megaloblastic anemia during pregnancy, but also as a vitamin necessary for reproductive health. Folate plays an important role in several metabolic processes including DNA synthesis and methylation. Changes in folate status can affect the stability and integrity of DNA or affect the methylation patterns of some tissues. Folate is required for cell division and cell maintenance, as it acts as a co-enzyme in the transfer and processing of carbon units and plays an important role in the synthesis of nucleotides (thymidine) that are essential for de novo construction or DNA repair. The purpose of this article is to examine the function of folic acid in human health especially in pregnancy and to evaluate the benefits, concerns, and epigenetic effects of maternal FA in light of recent discoveries that are crucial for the development of future research.