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All Journal Medicina E-Jurnal Medika Udayana Berkala Ilmu Kesehatan Kulit dan Kelamin ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Biomedika dan Kesehatan Bali Dermatology and Venereology Journal MAHESA : Malahayati Health Student Journal Eduvest - Journal of Universal Studies Bali Dermatology Venereology and Aesthetic Journal
I Gusti Ayu Agung Dwi Karmila
Departemen Dermatologi Dan Venereologi FK Udayana / RSUP Prof. Dr. IGNG Ngoerah Denpasar, Bali, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

 1 
Borderline Lepromatous Leprosy with Severe Erythema Nodosum Leprosum: A Case Report Nevristia Pratama; Luh Made Mas Rusyati; Prima Sanjiwani Saraswati Sudarsa; IGAA Dwi Karmila; NLP Ratih Vibriyanti Karna
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.210-216

Abstract

Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae (M. leprae) that primarily infects Schwann cells in the peripheral nerves, leading to nerve damage and the development of disabilities. In 2018, Indonesia was the third country with the most leprosy cases in the world. Erythema nodosum leprosum (ENL), also known as type II leprosy reaction, is a severe immune-mediated complication of multibacillary leprosy. Purpose: To report a case of borderline lepromatous leprosy with severe ENL. Case: A 49-year-old Balinese man presented with multiple tender erythematous skin nodules all over his body, fever, arthralgia, bilateral cervical lymphadenopathy, and sensory loss for the past week. The acid-fast bacilli bacteriological examination showed a positive result. The patient was diagnosed with borderline lepromatous (BL) leprosy with severe ENL and was treated with multibacillary multidrug therapy (MB MDT), methylprednisolone, and other symptomatic medications. After 1 month of treatment, there was an improvement in skin lesions. The MB-MDT treatment was continued and methylprednisolone was planned to be tapered down gradually. Discussion: Approximately 20-50% of all leprosy patients show leprosy reactions in the course of the disease. The goals of treatment for severe ENL are to control inflammation, reduce pain, treat neuritis to prevent nerve dysfunction and contractures, and prevent recurring ENL. The prognosis of leprosy with ENL reactions depends on the severity of the occurring leprosy reaction; early diagnosis and prompt treatment; and patient compliance with treatment. Conclusion: Early diagnosis and treatment are essential to avoid deformities in leprosy patients.
Nevus Unius Lateris (NUL) in a Theree-Year-Old Child Treated by Tretinoin 0.025%, Desoxymethasone 0.25%, and Urea 20% Cream Stephanie, Aurelia; Vibriyanti Karna, NLP Ratih; Karmila, IGAA Dwi; Laksmi, Hermina; Stella, Aurelia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.149-152

Abstract

Background: Linear verrucous epidermal nevus is the most frequent variant of the epidermal nevus classification. Linear verrucous epidermal nevus is characterized by the proliferation of epithelium arranged in a configuration that follows Blaschko's line. Nevus unius lateris (NUL) is a variant of the verrucous epidermal nevus, which has a unilateral distribution of lesions. Lesions are usually found at birth or in the first year of life as brown to grey verrucous papules or papillomatous plaques. The management of NUL is challenging as the results are varied and there is a high risk of recurrence. Purpose: to report a case of NUL and its management, especially in children. Case: A 3-year-old girl presented with brownish spots and multiple small lumps on the left buttock that have extended to the left leg since she was 9-days-old. On dermatologic examination, there were numerous hyperpigmented verrucous papules and plaques along the Blaschko line over the affected area. In this case, the diagnosis of NUL, is based on clinical symptoms and dermoscopy examination showed multiple large brown oval or round structures with hyperpigmented brown border. The patient was treated with combination topical therapy of tretinoin 0.025%, corticosteroid desoxymethasone 0.25%, and urea 20% cream, and the lesion improved within four weeks. Discussion: Epidermal nevus is often cosmetically disturbing. The treatment is still challenging and various, including surgical and non-surgical, but none is ideal and could potentially recur over months or years. dst. 
Effect of 8% Purple Sweet Potato Extract Cream on Wrinkle Reduction, Skin Moisture, and Elasticity Laksmi, I Gusti Ayu Agung Mini; Praharsini, I Gusti Ayu Agung; Karmila, I Gusti Ayu Agung Dwi; Rusyati, Luh Made Mas; Suryawati, Nyoman; Winaya, Ketut Kwartantaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.1-8

Abstract

Background: Purple sweet potato has been shown to contain anthocyanins, polyphenols, flavonoids, and tannins that act as antioxidants and have the potential to correct signs of aging in the skin, such as wrinkles, lack of hydration, and pigmentation. Purpose: to known the potential of 8% purple sweet potato extract for wrinkles, moisture, and elasticity. Methods: A one-group experimental study with pre and post-test assessment. The subject is women with photoaging aged 30-45 years. A pre-test was conducted by examining wrinkles using the Glogau scale and a simple A-one scanner, treatment with 8% purple sweet potato extract cream for 6 weeks, and then a post-test at the end of the 6th week to check wrinkles, moisture, and elasticity using a simple A-one scan. Statistical tests using the SPSS program, version 25.0. The analysis performed was descriptive statistical and comparative analysis using a paired T test.  Result: A total of 25 respondents with a mean age ± SD of 38.22 ± 4.23 years, the most Glogau scale in type 2 is 22 respondents (88%), the most sun exposure for 30 minutes per day is 14 respondents (56%). The degree of wrinkles decreased after treatment -4.960±1.353 [95% CI -7.681-(-2.239); P=0.001]. The degree of moisture increased after treatment 8.840±2.990% (95% CI 2.829-14.851; P=0.005. The degree of elasticity increased after treatment 14.840±4.623 (95% CI 5.544-24.136; P=0.002). Conclusion: 8% purple sweet potato extract can reduce the degree of wrinkles, improve the degree of skin moisture, and improve the degree of skin elasticity.
Co-Authors Adeline Santoso Adeline Santoso ajisma, Seva Anak Agung Gde Putra Wiraguna Aurelia Stephanie Darmaputra, I Gusti Nyoman Henny Wijaya I Gde Nengah Adhilaksman I Gde Nengah Adhilaksman Sunyamurti Wirawan I Gusti Ayu Agung Elis Indira I Gusti Ayu Agung Praharsini I Gusti Ayu Agung Praharsisni I Gusti Nyoman Darmaputra I Ketut Agus Somia Indira, I Gusti Ayu Agung Elis Joanne Roxanne Ketut Kwartantaya Winaya Ketut Wida Komalasari Laksmi, Hermina Laksmi, I Gusti Ayu Agung Mini Luh Made Mas Rusyati Made Hermina Laksmi Made Martina Windari Made Sanitca Indah Made Swastika Adiguna Made Wardhana Marrietta Sugiarti Sadeli Marrietta Sugiarti Sadeli Natih, Sintha Aprillia Gita Nevristia Pratama Ni Kadek Setyawati, Ni Kadek Ni Luh Putu Ratih Vibriyanti Karna Ni Made Dwi Puspawati Nyoman Suryawati Nyoman Yoga Maya Pramita Nyoman Yoga Maya Pramita Prima Saraswati Sanjiwani Sudarsa Primasari, Putu Yunita Putu Ayu Saraswati Putu Dyah Sawitri Putu Dyah Sawitri Putu Gde Hari Wangsa Rania Ayu Permata Putri Kornia Ratih Purnamasari Nukana Ricky Fernando Maharis Rikcy Fernando Maharis Sadeli, Marrietta Sugiarti Santoso, Adeline Sawitri, Putu Dyah Sayu Widiawati, Sayu Stella, Aurelia Stephanie, Aurelia Sutiawan, Indry Salonika Vibriyanti Karna, NLP Ratih Winaya, Ketut Kwartantaya Wiraguna, A.A.G.P