Nyoman Suryawati
Departemen Dermatologi And Venereologi, Fakultas Kedokteran, Universitas Udayana-RSUP Sanglah Denpasar, Bali, Indonesia

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Journal : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Innovative approach of nanoformula moisturizer applications in atopic dermatitis: a review Nyoman Suryawati; Made Wardhana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 53, No 2 (2021)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.982 KB) | DOI: 10.19106/JMedSci005302202112

Abstract

The skin barrier defect is the first step in the development of atopic dermatitis (AD). Various therapeutic guidelines recommend using moisturizers to maintain the skin barrier and the prevention of AD. The use of a moisturizer in the form of barrier cream is considered to improve the skin barrier. However, this dosage form is occlusion and has an oily texture, resulting in patient noncompliance with therapy. Various techniques were developed to improve patient compliance in applying topical preparations, one of which is by developing nanotechnology. Recent studies aim to develop nanoformula preparations because they can help deliver drug molecules to specific targets with minimize side effects. The application of nanoformula moisturizer is promising in the management of AD because of its ability to reduce water loss and prevent irritation and produce formulations with a thinner texture to increase therapeutic compliance in AD patients. 
Characteristics of lower extremity ulcers among patients treated at Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali Puspita Sari, Luh Gede Melia; Suryawati, Nyoman
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 4 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005504202302

Abstract

Lower extremity ulcers are one of the ulcers that are difficult to heal. This condition causes significant morbidity, mortality, costs, and reduces the quality of life. Epidemiological studies in Indonesia often focus on diabetic foot ulcers, so a general description of lower extremity ulcers is still lacking. This study aimed to determine the characteristics of lower extremity ulcers in outpatients at the Dermatology and Venereology Outpatient Polyclinic, Prof. Dr. I.G.N.G Ngoerah General Hospital, Denpasar, Bali. The data were taken retrospectively from medical records from January 2018 until December 2021. A total of 15 subjects were enrolled in this study. Among the subjects, 8 (53.3%) were male and 7 (46.6%) were female. The age group of 40 yo and over dominated this study (60%). The common ulcer predilection was on the cruris (42.1%) and the wound culture results were dominated by Staphylococcus aureus (40%). Comorbidities were found in 7 subjects (46.7%) and the majority was hypertension (42.8%). Several subjects also had additional diagnoses at the time of the visit, including Morbus Hansen (60%), deep vein thrombosis (10%), cellulitis (10%), pyoderma gangrenosum (10%), and systemic lupus erythematosus (10%). In conclusion, the most characteristics of lower extremity ulcer patients at Prof. Dr. I.G.N.G Ngoerah General Hospital  are males, age group > 40 yr, with cruris as a predilection, and hypertension as the most common comorbid.
Co-Authors Aditya Permana Aditya Permana Anang Endaryanto Andrew Wicaksono Aurelia Stephanie Bagus Bagus Bharata, Putu Evindya Vipascitadewi Nandanaya Christiana Paramita Cita Rosita Sigit Prakoeswa Darmaputra, I Gusti Nyoman Djuanda, Kevin Jonathan Duarsa, Putu Laksmi Anggari Putri Elis Indira, I Gusti Ayu Agung Evy Ervianti Gede Mahadika Pradipta Atmaja Gunawan, Regina Hasri Dewi Herman Saputra Herman Saputra Herman Saputra I Gde Nengah Adhilaksman I Gde Nengah Adhilaksman I Gusti Ayu Agung Dwi Karmila I Gusti Ayu Agung Elis Indira I Gusti Ayu Agung Praharsini I Gusti Ayu Agung Praharsisni I Gusti Nyoman Darmaputra I. G. A. A. Elis Indira Ida Ayu Uttari Priyadarshini IGAA Ellis Indira IGAA Praharsini Indira, I Gusti Ayu Agung Elis Indira, IGAA Ellis Jason Jonathan Jihan Prani Wibowo Juliari, Gusti Ayu Made Juliyanti Juliyanti - Juliyanti -, Juliyanti Ketut Kwartantaya Winaya Khathreen, Corry Laksmi, I Gusti Ayu Agung Mini Linda Astari, Linda Luh Gede Melia Puspita Sari Luh Made Mas Rusyati Made Martina Windari Made Swastika Adiguna Made Wardhana Mohana Naravenah Ni Kadek Yunita Arsita Dewi Ni Luh Putu Ratih Vibriyanti Karna Ni Made Dwi Puspawati Ni Putu Melda Dharmahayu Nyoman Upadana Nyoman Yoga Maya Pramita Paramahamsa, Shirdi Paramita, Christiana Praharsini, IGAA Pramita, I Gusti Ayu Sattwika Prima Saraswati Sanjiwani Sudarsa Primasari, Putu Yunita Putu Yonika Budiarisma Ricky Fernando Maharis Sanjiwani, Saraswati Prima Saraswati Prima Sanjiwani Saraswati Sudarsa, Prima Sanjiwani Sutiawan, Indry Salonika Wicaksono, Rafael Lilik Winaya, Ketut Kwartantaya