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Antidepressant Activity Study of Keruing (Dipterocarpus grandiflorus) Oleoresin Candle Aromatherapy on Male Mice (Mus musculus) Balb/C Strain Agus, Adhe Septa Ryant; Butar-Butar, Maria Elvina Tresia; Fernandes, Andrian; Maharani, Rizki; Awan, Kevin Imanuel; Luhat, Martin Gilbert
Camellia : Clinical, Pharmaceutical, Analytical and Pharmacy Community Journal Vol 3 No 2 (2024): Camellia (Clinical, Pharmaceutical, Analytical, and Pharmacy Community Journal)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/cam.v3i2.24665

Abstract

Depression represents a manifestation of prolonged stress, which, if left untreated, may lead to severe mental disorders. For depression treatment therapy, it can be carried out based on evidence-based treatment for depression and anxiety. Aromatherapy candles can be used as a non-pharmacological medium for depression therapy, where keruing has active compounds are phthalic acid di(3-methoxybenzyl) ester and phthalic acid, 5-ethyl-1,3-dioxan-5-yl octyl ester, causing keruing oleoresin to have a distinctive fragrance. This study aims to evaluate the pharmacological potential of keruing as an antidepressant for non-pharmacological therapy. Aromatherapy candles were formulated with keruing oleoresin at concentrations of 0%, 2.5%, 5%, 7.5%, and 10%, followed by testing their antidepressant activity using the Conditioned Place Preference (CPP) method. The results of the Paired T-test for groups F0, F2, and F4 or formulas containing 0%, 5%, and 10% of keruing oleoresin have a significant effect (sig. values <0.05) between pre and post-test being given aromatherapy and induction. In the One-way ANOVA test, between their groups, it can be seen there was no significant difference in test activity, namely for the pre-treatment test (sig. 0.445 > 0.05) and for the post-treatment test (sig. 0.065 > 0.05). Results indicated that while the candles met physical quality standards outlined by the Indonesian National Standard (SNI), no significant antidepressant effects were observed in mice. Further refinement in methodology, including the concentration of active compounds and delivery methods, is recommended to enhance the pharmacological potential of keruing oleoresin.
Training and Mentoring Strengthening Literacy and Numeracy in Recovery Learning in Musi Banyuasin Regency Camellia; Maharani, Rizki; Kurnisar, Kurnisar; Nila Sari; Muhammad Alipraja; Nuraini, Nuraini; Alfayyad, Syahriza
Unram Journal of Community Service Vol. 5 No. 4 (2024): December
Publisher : Pascasarjana Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ujcs.v5i4.759

Abstract

They are strengthening training and mentoring​​​ literacy and numeracy in Musi Banyuasin Regency through training and mentoring for Principals and Vice Curriculum in Junior High Schools (SMP). Based on the results of the National Assessment and the Program for International Students Assessment (PISA) 2022, post-pandemic learning recovery is essential in Indonesia, especially in improving student literacy and numeracy. This activity aims to strengthen participants' understanding and competence in designing and implementing learning that integrates literacy and numeracy by the Merdeka Curriculum. The methods used in this activity include counselling, intensive training, and assistance in designing learning tools, such as Learning Implementation Plans (RPP), learning media, and assessments. The activity also includes evaluation through pretests and posttests to measure changes in participant understanding. The results show significant improvement in literacy and numeracy understanding, with the average posttest score of participants increasing from 50 to 70. The evaluation results showed high satisfaction from participants with the material provided and its relevance to needs in the field. This activity strengthened collaboration between education managers and learning communities and positively impacted the recovery of education quality in Musi Banyuasin Regency post-pandemic. Hopefully, this activity can be sustainable in improving literacy and numeracy at the junior high school level.
CHEMICAL AND ORGANOLEPTIC PROPERTIES OF BEKAI (Pycnarrhena tumefacta Miers) LEAVES FOR FLAVOURING AGENT (BIO-VETSIN) Maharani, Rizki; Fernandes, Andrian; Turjaman, Maman; Kuspradini, Harlinda; Lukmandaru, Ganis
Indonesian Journal of Forestry Research Vol. 7 No. 2 (2020): Indonesian Journal of Forestry Research
Publisher : Association of Indonesian Forestry and Environment Researchers and Technicians

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59465/ijfr.2020.7.2.121-133

Abstract

The "tasty" cuisine tends to use chemical flavour agent containing monosodium glutamate (M.S.G.). M.S.G. utilizations, in long-term, may cause health problems, especially triggering cancer cells. Therefore necessary to introducing and increasing a natural flavouring agent to eliminate those health problem, such as bekai leaf. Bekai (Pycnarrhena tumefacta Miers) is familiar as a natural flavour agent (bio-vetsin) in cuisine for forest communities in Nyapa Indah Village, Berau, East Kalimantan, Indonesia. However, until now there has been no proper analysis support for widespread utilization of bekai leaf. This paper studies the presence of phytochemicals, antioxidant and GC MS analysis from bekai leaf extracts, as well as five hedonic classifications of organoleptic test, to reinforce the need for a better understanding of consumers reaction in terms of possible acceptance of additional bekai leaves applied in soup as bio-vetsin. Present study showed that the qualitative screening of phytochemical compounds in bekai leaves ethanolic extracts revealed presence of alkaloids, flavonoids, tannins and steroids. Antioxidants of bekai leaves using 2,2-diphenyl-1-picrylhydrazy (DPPH) method showed that concentrated extract has 80.1%, which predicted can improve immune for inhibitory action of cancer cells. GC MS analysis suspected that bekai leaf extract contained 5 (five) major compounds, i.e. oxirane dodecyl, gamma sitosterol, vitamin E (α tokoferol), 9.12-Octadecadienoic acid (Z,Z)- (natural linoleic acid), and 3-Tetradecanynoic acid (myristic acid). These chemical compound in related with their phytochemical were predicted to contained strong antioxidant activities and some of them commonly used as flavour agent in cuisine for some food industries.
Teacher Empowerment in the Development of Artificial Intelligence (AI)-Based Learning Media in Meranjat Village Ogan Ilir Regency Chotimah, Umi; Waluyati, Sri Artati; Camellia; Maharani, Rizki; Alipraja, Muhammad; Erlande, Rike; Amziyah, Dini; Valentin, Della; Rosadi, Yudisia Sofani Putra; Naila, Siti; Patricia, Putri
Unram Journal of Community Service Vol. 6 No. 4 (2025): December: In Progress
Publisher : Pascasarjana Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ujcs.v6i4.1277

Abstract

Training on the use of Artificial Intelligence-based learning media was held as part of teacher empowerment activities in developing such media. This community service activity was held by the Civic Education Study Program, Faculty of Teacher Training and Education, Sriwijaya University. The Community Service Team trained teachers at SMPN 1 Indralaya Selatan, Meranjat Village, Ogan Ilir Regency, to develop Artificial Intelligence (AI)-based learning media. This training and mentoring aimed to improve teachers' capabilities so they could create innovative and effective learning. The methods applied included counseling, training, and mentoring in direct practice using Artificial Intelligence-based media from Wayground AI, Canva AI, Avatar AI, Renderforest AI, LMS AI, and ChatGPT AI, as well as assessments through pretests and posttests to measure the increase in participants' understanding. The results showed a significant increase in understanding of creating Artificial Intelligence-based learning media, with the average post-test score of participants increasing from 37.7 to 80.03 from a total of 30 participants. The evaluation results showed high satisfaction from participants with the material provided and its relevance to needs in the field. The participants' response was very positive, as evidenced by their active discussions, willingness to experiment with the media, and commitment to creating learning products. The program is planned to continue with follow-up publications in newspapers, YouTube, and journals, as well as evaluation meetings and activity reports. It is hoped that this program will continue to empower teachers to improve and develop AI-based learning media in schools.