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EFFECTS OF RED DRAGON FRUIT PEEL EXTRACT ADMINISTRATION ON NEUTROPHIL COUNTS FOLLOWING PERIAPICAL RADIOGRAPHY EXPOSURE Maydina Izzatul Yazidah; Didit Aspriyanto; Renie Kumala Dewi
Dentino : Jurnal Kedokteran Gigi Vol 6, No 2 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i2.11998

Abstract

Background: Radiation exposure from periapical imaging can cause cell damage in various tissues due to the formation of free radicals. Cell damage in the tissue can be observed from the number of neutrophils which are immune cells. Free radicals can be suppressed by administering exogenous antioxidants. One source of natural antioxidants is red dragon fruit, especially on its peel. Objective: To analyze the effect of periapical imaging x-ray radiation exposure after the administration of red dragon fruit peel extract on absolute neutrophil counts in mice. Method: This research was a true experimental study with a post-test only and control group design using 24 mice that were divided into 6 groups. The control group was not given any treatment while P1 to P5 group were given red dragon fruit peel extract at a dose of 100 mg/kg BW and exposed to radiation with different exposures. P1 group was exposed 1 time (0.63 mGy), P2 group was exposed 4 times (1.66 mGy), P3 group was exposed 8 times (4.37 mGy), P4 group was exposed 12 times (8.19 mGy), and group P5 was given no exposure. Results: There were changes in the number of neutrophils in all groups. The LSD Posthoc test results showed a significant difference between the control group (12.470 / mm3) and the P5 group (12.470 / mm3) compared to P3 group with 8 times exposure (40.348 / mm3). Conclusion: There is an effect of periapical radiographic x-ray radiation exposure by red dragon fruit peel extract on the absolute neutrophil count in mice. Keywords: Antioxidants, Neutrophils, Periapical Radiography, Radiation, Red Dragon Fruit Peel.
THE EFFECT OF RAMANIA LEAF (Bouea macrophylla Griff) EXTRACT GEL ON COLLAGEN FIBERS DENSITY IN INCISIONAL WOUND OF MALE WISTAR RATS Dinda Rizkia; Irham Taufiqurrahman; Renie Kumala Dewi
Dentino : Jurnal Kedokteran Gigi Vol 6, No 1 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i1.10648

Abstract

ABSTRACTBackground: Ramania leaf (Bouea macrophylla Griff) extract gel has secondary metabolites in the form of flavonoids, steroids, phenols and terpenoids which have a role as antioxidant. They will protect the body from excessive production of reactive oxygen species (ROS) by increasing endogenous antioxidants SOD, CAT and GPX, so that wound healing will not be inhibited and the process of collagen synthesis can run smoothly. Objective: To analyze the effect of ramania leaf extract gel that was applied topically with 5%, 10% and 15% concentration on collagen fibers density in incisional wound of male Wistar rats (Rattus norvegicus) on the 7th and the 14th day. Method: This research is a pure experimental study with a posttest-only control group design, using 24 rats which were divided into 4 groups: the treatment groups given ramania leaf extract gel of 5%, 10%, 15%, and the control group given placebo gel. The application of the extract gel was done once within 24 hours. The collagen level was measured with a spectrophotometer on the 7th and the 14th day. Results: Two-Way ANOVA test results on the 7th and the 14th day of each group showed a significant difference with p=0.000 (p<0.05). The Bonferroni Post-hoc Test showed a significant difference with p<0.05 between the placebo gel group and the groups of ramania leaf extract gel of 5%, 10%, 15% on the 7th and the 14th day. Conclusion: There is an effect of ramania leaf extract gel on collagen fibers density with the most effective concentration of 15%.Keywords: Antioxidant, , Collagen, Ramania Leaf Extract Gel
MANAGEMENT OF CHRONIC LYMPHADENOPATHY WITH POOR ORAL HYGIENE IN CHILDREN (CASE REPORT) Renie Kumala Dewi
Dentino : Jurnal Kedokteran Gigi Vol 5, No 2 (2020)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v5i2.8950

Abstract

ABSTRACTBackground. Lymphadenopathy is a common clinical feeding an anomaly in the size and consistency of lymph nodes. Local bacterial infection causes cervical adenopathy when the lymph nodes responded to local infection. Cervical lymphadenopathy is a common problems in pediatric. Lymph node with more than 10 mm diameter is usually considered abnormal. Lymph node enlargement caused by a chronic infection is known as chronic lymphadenopathy. Objectives. Discovery management of chronic lymphadenopathy in children with poor oral hygiene.Case. A 9-year-old boy came to Pediatric Dentistry Specialist Gusti Hasan Aman Dental Hospital with his parents with a complaint of pain in his right tooth posterior mandible for the last week. The patient had received medication, however the pain still existed. Extraoral examination revealed symmetrical face, a node on the middle neck sizing 30 mm in diameter for 4 years. The lump was treated several times with no progress in size. Intraoral examination revealed a cavity in posterior lower left tooth and painful in the last 5 days without any treatment. Plaque score showed poor oral hygiene.Case Management. Based on extraoral examination, the nodule on the neck reduced in size from 30 mm to 7 mm after treatment with antibiotic, anti-inflammatory medication, dental care and control periodic for oral hygiene management. Conclusion. Early detection and accurate lymphadenopathy diagnosis is important for successful therapy. Oral hygiene improvement can help in the healing process of chronic lymphadenopathy which occurred for 4 years. Keyword:  Limphadenophaty chronic, Oral hygiene, Staphylococcus aureus
THE EFFECT OF BINJAI (Mangifera caesia) LEAVES EXTRACT GEL TO FIBROBLAST CELL NUMBER ON INCISION WOUND Noor Hildayanti; Irham Taufiqurrahman; Renie Kumala Dewi
Dentino : Jurnal Kedokteran Gigi Vol 6, No 2 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i2.12000

Abstract

Background: The ethanol extract of binjai leaves contains bioactive compounds that are saponin, tannin, triterpenoid, steroid, alkaloid and flavonoid which potentially as an anti-inflammation, anti-bacterial, and antioxidant. It can fasten and control the process of scar healing. The binjai leaves extract was made into gel preparation. The binjai leaves extract gel can affect fibroblast cell number during the proliferation phase. Purpose: To analyze the effect of binjai (Mangifera caesia) leaves extract gel to the fibroblast cell number on male wistar rats (Rattus norvegicus) incision wound.  Methods: This research design was a true laboratory experimental research with post-test only with control group design which used 24 male wistar rats and divided into 4 groups: the negative control group that was given the placebo gel and the treatment group that was given the binjai leaves extract gel with 5%, 10%, and 15% concentrations. Results: The result of Two-way ANOVA statistic test shows that there is a meaningful difference in the treatment group on the 7th day (p=0,000) and on the 14th day (p=0,000). The Post-Hoc Bonferroni test for fibroblast cell number on the 7th and 14th day shows that there is a meaningful difference (p<0,05) between the negative control group and the treatment group. Conclusion: Binjai leaves extract gel have an effect to the fibroblast cell number on male wistar rats incision wound with the most effective concentration of 15%. Keywords: Binjai leaves extract gel, Fibroblast cell number,  Flavonoid, Incision wound healing
INHIBITORY ACTIVITY OF ULIN BARK (Eusideroxylon zwageri) EXTRACT TO Lactobacillus acidophilus Ina Rezki Rahmasari; I Wayan Arya Krishnawan Firdaus; Renie Kumala Dewi
Dentino : Jurnal Kedokteran Gigi Vol 6, No 2 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i2.11989

Abstract

Background: Lactobacillus acidophilus is a bacterium  which plays a role in dental caries. It is believed as a pioneering bacterium in advanced caries and much likely to be isolated in dentin caries zone, resulting in the needed for tooth restoration. The use of 2% Chlorhexidine digluconate as cavity cleanser is recommended as an effort to prevent seconday caries but can cause side effects. One of the natural materials that can be used as a cavity cleanser is ulin bark extract (Eusideroxylon zwageri), a traditional medicine originally from Kalimantan, because it contains phenolic, flavonoid, tannin, alkaloid, saponin and terpenoid. Purpose: To discover the inhibitory activity of ulin bark extract on Lactobacillus acidophilus growth. Methods:  This was a true experimental laboratory and post test only with control group design, that used 20%, 40%, 60%, 80%, 100% concentrations of ulin bark extracts and  K(+) 2% Chlorhexidine digluconate. Difussion method was used to test inhibitory activity with 6 treatment groups and 4 replications, comprising a total of 24 samples. All groups were incubated for 24 hours at 37ºC temperature. The inhibition zone was measured using calipers. Results: The 20%, 40%, 60%, 80% and 100% concentration of ulin bark extracts and 2% Chlorhexidine digluconate had an average inhibition zone of 7.17 mm, 9.02 mm, 11.14 mm, 13.06 mm, 15.17 mm and 19.22 mm. One Way ANOVA and Post Hoc Bonferroni tests showed significant difference between all groups. Conclusion: Ulin bark extract can inhibit Lactobacillus acidophilus growth starting from 20%, 40%, 60%, 80% and 100% concentration.
EARLY TREATMENT OF CLASS II DIVISION 1 MALOCCLUSION USING TWIN BLOCK APPLIANCES: A CASE REPORT Renie Kumala Dewi; Seno Pradopo; Sindy Cornelia Nelwan
Dentino : Jurnal Kedokteran Gigi Vol 7, No 1 (2022)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v7i1.13111

Abstract

Background: Malocclusion is dentofacial growth deviation from its normal size and shape, thus causing abnormal occlusion. One of its etiology is heredity. Removable twin block, a functional appliance that can be used in interceptive orthodontic treatment, can be used to treat Class II malocclusion with large overjet in children during skeletal growth and development. Case: An 11-year-old boy came to pediatric dental specialist clinic with Class II division 1 Angle malocclusion (SNA 82°; SNB 74°; ANB 8°, CVM CS 4, overjet 14 mm, overbite 7 mm, and convex profile). Removable twin block for Class II malocclusion was chosen as the therapy. Case management: Removable twin block appliance with acrylic occlusal bite block was used on maxilla and mandible separately. An angle of 70° was made in the occlusal bite block, which was made based on the bite registration wax during centric occlusion. This device is used 24-hours a day. Monthly dental visit was done to reduce the maxillary and mandibular occlusal bite blocks. After 9 months, an overjet of 5 mm was obtained. Cephalometry calculations became SNA 82°; SNB 7 9 °; ANB 3 °. The patient was given further phase 2 treatment with fixed orthodontic appliance. Conclusion: With proper case selection and good patient cooperation, removable twin block appliance can correct skeletal malocclusion, improve facial profile, reduce overjet and overbite, and correct molar relations.
PENGARUH APLIKASI SODIUM FLUORIDE 2% TERHADAP JUMLAH KOLONI Streptococcus sp. DALAM SALIVA ANAK USIA 7-9 TAHUN Zainatun Nadhira; Nurdiana Dewi; Renie Kumala Dewi
Dentin Vol 4, No 3 (2020)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: Dental and oral health problems in Barito Kuala District is caused by wetland area with low acidity. The acidic of land water can support growth of acidogenic and asiduric bacteria that it can reduce pH of oral cavity. Sodium fluoride 2% is one of caries prevention agents because fluoride has antibacterial activity that works by inhibiting enolase enzyme in glycolysis process of oral bacteria. Purpose: To determine effect of 2% Sodium Fluoride on the number of Streptococcus sp. in saliva of children aged 7-9 years in  wetland area. Method: This study used true experimental with pre and post-test with control group design. Twenty subjects selected through simple random sampling and divided into two groups: study group were given  aplication of Sodium Fluoride 2% and control group were not given the application of Sodium Fluoride 2%. Results: Paired t-test results showed a significant difference in p-value (p=0,000) in number of Streptococcus sp. in study group. There was no significant difference in p-value (p=0,056) in the number of Streptococcus sp. in control group. Conclusion: There was an effect of the application of Sodium Fluoride 2% to the number of Streptococcus sp. in saliva of children aged 7-9 years in wetland area. Keywords : Saliva, Sodium Fluoride, Streptococcus sp, Wetlands ABSTRAKLatar Belakang: Masalah kesehatan gigi dan mulut di Kabupaten Barito Kuala disebabkan wilayah tersebut merupakan lahan basah yang memiliki air dengan tingkat keasaman rendah. Sifat asam yang dimiliki air lahan tersebut dapat mendukung pertumbuhan bakteri yang bersifat asidogenik dan asidurik sehingga dapat menurunkan pH rongga mulut. Sodium fluoride 2% adalah salah satu agen pencegahan karies karena fluor memiliki aktivitas antibakteri yang bekerja dengan cara menghambat enzim enolase pada proses glikolisis bakteri rongga mulut. Tujuan: Mengetahui pengaruh Sodium Fluoride 2% terhadap jumlah koloni bakteri Streptococcus sp. dalam saliva anak usia 7-9 tahun pada wilayah lahan basah. Metode: Penelitian ini merupakan eksperimental murni dengan rancangan pre and post-test with control group design. Dua puluh subyek dipilih melalui simple random samling dan dibagi menjadi dua kelompok: kelompok perlakuan yang diberikan aplikasi Sodium Fluoride 2% dan kelompok kontrol yang tidak diberikan aplikasi Sodium Fluoride 2%. Hasil: Hasil uji t-berpasangan menunjukkan ada perbedaan bermakna (p=0,000) pada jumlah koloni Streptococcus sp. pada kelompok perlakuan. Tidak terdapat perbedaan yang bermakna (p=0,056) pada jumlah koloni Streptococcus sp. pada kelompok kontrol. Kesimpulan: Terdapat pengaruh aplikasi Sodium Fluoride 2% terhadap jumlah koloni Streptococcus sp. dalam saliva anak usia 7-9 tahun pada wilayah lahan basah. Kata Kunci : Lahan basah, Saliva, Sodium Fluoride, Streptococcus sp
UJI KITOSAN SISIK IKAN HARUAN (Channa striata) TERHADAP AKTIVITAS ENZIM GLUKOSILTRANSFERASE Streptococcus mutans Moch. Andhika Firdausi Rachfa; Deby Kania Tri Putri; Renie Kumala Dewi
Dentin Vol 5, No 2 (2021)
Publisher : Universitas Lambung Mangkurat

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Abstract

ABSTRACTBackground: Streptococcus mutans is a bacterium that acts as the main agent for dental caries. These bacteria have glucosyltransferase (GTF) enzyme which can catalyze sucrose into adhesive glucans, this pathogen nature also plays a role in biofilm structures. Haruan fish (Channa striata) of chitosan known as a natural ingredient which has antibacterial properties, the content of amine groups (NH2) in chitosan can inhibit the activity of the GTF enzyme from Streptococcus mutans Purpose: To explain the effect of chitosan from haruan fish scales on the activity of the enzyme Glucosyltransferase Streptococcus mutans. Methods: This research was a true experimental study with a post-test only design with control group design using haruan fish scales chitosan with concentration of 1.5%, 2.5%, 3.5%, 4% and measured using High Performance Liquid Chromatography HPLC to see activity of the glucosyltransferase enzyme. Results: This study showed that 1.5% concentration of haruan fish scales chitosan was able to inhibit the enzyme activity with a value of 82.689 unit. Conclusion: Haruan fish scales chitosan with concentration 1.5%, 2.5%, 3.5%, 4% has the same ability as 0.2% Chlorhexidine gluconate in inhibiting the activity of the GTF S. mutans enzyme. Key words: Chitosan, glucosyltransferase enzyme, HPLC, Streptococcus mutans. ABSTRAKLatar Belakang: Streptococcus mutans merupakan bakteri yang berperan sebagai agen utama terjadinya karies gigi. Bakteri ini memiliki enzim glukosiltransferase (GTF) yang dapat mengkatalis sukrosa menjadi glukan yang bersifat adhesive sehingga meningkatkan perlekatan bakteri, sifat patogen ini juga berperan dalam pembentukan struktur biofilm. Kitosan sisik ikan haruan (Channa striataGen gtfB, gtfC, gtfD) diketahui sebagai bahan alami yang memiliki sifat antibakteri. Kandungan gugus amina (NH2) dalam kitosan ikan haruan dapat menghambat aktivitas enzim GTF Streptococcus mutans. Tujuan: Menjelaskan pengaruh kitosan sisik ikan haruan (Channa striata) Terhadap aktivitas enzim Glukosiltransferase Streptococcus mutans. Metode: penelitian true experimental dengan rancangan post test only with control group design menggunakan kitosan sisik ikan haruan konsentrasi 1,5%, 2,5%, 3,5%, 4% dan diukur menggunakan High Performance Liquid Chromatography (HPLC) untuk melihat aktivitas enzim glukosiltransferase. Hasil: Hasil dari pengujian menunjukkan bahwa kitosan sisik ikan haruan konsentrasi 1,5% sudah mampu menghambat aktivitas enzim dengan nilai 82,689unit Kesimpulan: Kitosan sisik ikan haruan konsentrasi 1,5%, 2,5%, 3,5%, 4% memiliki kemampuan yang setara dengan Chlorhexidine gluconate 0,2% dalam menghambat aktivitas enzim GTF S. mutans. Kata kunci : Enzim Glukosiltransferase, HPLC, Kitosan, Streptococcus mutans.
The Impact of Marketing Mix on the Number of Visits to Pediatric Dentists in Banjarmasin during the Covid 19 Pandemic Ika Kusuma Wardani; Erika Norfitriah; Amalda Ayu Utami Hasibuan; Nadia Febrila Putri; Renie Kumala Dewi
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2369

Abstract

The high number of dental problems in children hurts children's health. Pediatric dentists were deemed necessary to improve marketing strategies which were expected to attract visits to pediatric dentists. This study aims to analyze the impact of the marketing mix on the number of visits to pediatric dentists in Banjarmasin City during the covid 19 pandemic. This study used a cross-sectional quantitative method. The sampling technique used purposive sampling. Data were taken using a questionnaire that previously has been tested for validity and reliability. Data were analyzed using a multiple linear regression test. Product, promotion, and people partially have no significant impact on the number of visits to the pediatric dentist in Banjarmasin City during the covid 19 pandemics. Marketing mix has a simultaneous impact on the number of visits.
Pemberdayaan Kaporagi Dalam Mengurangi Angka Kejadian Karies Gigi Balita Di Lahan Basah renie kumala dewi; I Wayan Arya Krishnawan Firdaus; Anugrah Qatrunnada Hakim
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 3 (2020): Peran Perguruan Tinggi dan Dunia Usaha Dalam Pemberdayaan Masyarakat Untuk Menyongsong
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.357 KB) | DOI: 10.37695/pkmcsr.v3i0.753

Abstract

Karies gigi adalah suatu proses patologis yaitu kerusakan pada jaringan keras gigi yang dimulai dari enamel menuju dentin dikarenakan rongga mulut yang bersifat asam. Berdasarkan Riset Kesehatan Dasar tahun 2018 di Indonesia, prevalensi karies gigi anak usia dini sangat tinggi yaitu 93%. Kota Banjarmasin sebagian besar merupakan lahan basah, terdiri dari rawa dengan struktur tanah lahan gambut yang menghasilkan air dengan tingkat keasaman pH 3,5-4,5. Rongga mulut yang terpapar air lahan gambut akan berpengaruh pada derajat keasaman rongga mulut sehingga dapat terjadi karies gigi dengan cepat. Berdasarkan latar belakang tersebut maka perlu adanya tindakan pencegahan karies gigi lebih lajut dengan pemberian vaksin gigi dengan tooth mouse oleh KAPORAGI kepada balita. Kader posyandu fakultas kedokteran gigi (KAPORAGI) adalah orang yang terorganisir oleh dosen PKM FKG ULM yang bekerja sebagai kader posyandu dari suatu wilayah oleh puskesmas dinas kesehatan setempat, serta diberikan penyuluhan dan buku panduan mengenai kesehatan gigi dan mulut sehingga dapat diinformasikan kepada masyarakat setempat terutama ibu dan balita. Diharapkan dengan usaha pemberian vaksin gigi dengan tooth mouse oleh KAPORAGI dapat mengurangi angka kejadian karies sejak dini pada balita, meningkatkan oral hygine serta meningkatkan kualitas hidup anak dan terciptanya program Indonesia bebas karies 2030.