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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Biota Majalah Obat Tradisional Pharmascience Jurnal Surya Medika ALCHEMY Jurnal Penelitian Kimia JFL : Jurnal Farmasi Lampung Journal of Midwifery and Nursing Jurnal Kesehatan Journal of Multidisciplinary Applied Natural Science Jurnal Inovasi Pembangunan Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Jurnal Bakti Untuk Negeri Safari : Jurnal Pengabdian Masyarakat Indonesia Jurnal Nusantara Berbakti Borneo Journal of Pharmacy
Viogenta, Pratika
Prodi Farmasi FMIPA, Universitas Lambung Mangkurat, BanjarBaru
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The Characterization of Capsule Shell from Acid-Hydrolyzed Palm Oil Starch Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Desy Aulia Azzahra
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.93550.72-81

Abstract

Acid hydrolysis of palm trunk starch can increase the amylose content in starch, providing a stronger and more stable film. This study aims to obtain the best-modified starch concentration ratio with hydroxypropyl methylcellulose (HPMC) and identify their characteristics. Modifying palm trunk starch was conducted with an acetic buffer using CH3COONa and CH3COOH, decolorizing starch with activated carbon. Manufacturing a capsule shell was performed with weight ratio variations of modified starch and HPMC 1:1 (F1), 2:1 (F2), and 3:1 (F3). All formulations produced firm and elastic capsule shells. The capsule products were consistent in an average weight of F1 (0.10 g), F2 (0.11 g), and F3 (0.14 g). The average disintegration test results were F1 (10 minutes, 27.57 seconds), F2 (6 minutes, 47.06 seconds), and F3 (4 minutes, 34.24 seconds). Tensile strength results were F1 (2.147 MPa), F2 (2.565 MPa), and F3 (2.159 MPa). Fourier Transform Infrared (FTIR) results showed a vibration at a wavenumber of 1560 cm-1 corresponding to the characteristic fingerprint of the C–O vibration stretching in the capsule shell made from starch modified by HPMC. The concentration of modified starch affects the capsule shell’s characteristics, showing that capsule shell F2 (2:1) has the best formulation.
Physical Stability and Antioxidant Peel-Off Kefir Mask Arachi (Arachis Hypogaea L) Khairunnisa, Amalia; Kartinah, Nani; Viogenta, Pratika; Mulia, Mulia
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 1: March 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i1.28501

Abstract

The fermented product sector can produce kefir for use in cosmetic preparations. Kefir has weak storage stability and strong antioxidant properties, making it a suitable raw material for cosmetic formulations. The purpose of this study is to determine the best concentration of peanut kefir in Peel-off mask Arachi through antioxidant activity and physical stability during seven cycles of room temperature storage and freeze-thaw (4±2ºC and 40±2ºC). Using the DPPH method based on the IC50 value, the antioxidant activity test was conducted. It was retested after 7 cycles or 28 days. At ambient temperature and freeze-thaw temperature, organoleptic tests, pH, adhesion, and spreadability were conducted in cycles ranging from 0 to 7. The peel-off kefir mask preparations with F1 (0.5%), F2 (1%), and F3 (2%), concentrations created a homogeneous, viscous preparation that was stable at room temperature and freeze-thaw stable for seven cycles, according to the results. In terms of the pH test, the sample showed a drop in pH following storage, stable adhesion for up to seven cycles. However, for F1, the adhesion was not stable in either scenario. With a significant activity category, the formula's antioxidant activity also declines in IC50 values. Therefore, it can be said that even though the peel-off mask preparation changed after storage in a few different ways, it still falls short of the threshold in terms of the physical characteristics of the cosmetic preparation.
Potensi Ekstrak Metanol, Fraksi N-Heksana dan Etil Asetat Daun Kasturi (Mangifera Casturi Kosterm) Terhadap Aktivitasnya Sebagai Anti Bakteri: Potential of Methanol Extract, N-Hexane Fraction and Ethyl Acetate of Kasturi Leaves (Mangifera Casturi Kosterm) for Their Anti-Bacterial Activity Sutomo, Sutomo; Fajri, Ahmad; Viogenta, Pratika; Arnida, Arnida; Wathan, Nasrul
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.8484

Abstract

Salah satu tumbuhan obat yang secara empiris memiliki aktivitas antibakteri adalah kasturi (Mangifera casturi). Tumbuhan M. casturi merupakan salah satu tumbuhan khas Kalimantan. Penelitian ini bertujuan menentukan aktivitas antibakteri ekstrak metanol, fraksi n-heksan dan fraksi etil asetat daun M. casturi terhadap bakteri Staphyloccocus aureus, Eschericia coli, dan Salmonella typhi. Metode yang digunakan pada penelitian ini yakni metode Kirby-bauer dan Bioautografi dengan konsentrasi ekstrak metanol, fraksi n-heksan dan fraksi etil asetat  sebesar 5, 10, dan 15% serta kontrol positif siprofloksasin dan kontrol negatif Na-CMC 0,5%. Hasil menunjukkan bahwa diameter zona hambat ekstrak metanol, fraksi n-heksana dan fraksi etil asetat secara berurutan didapat 14,4; 9,21; dan 14,63 mm pada bakteri St. aureus, 14,43; 16,01; dan 17,21 mm pada bakteri E. coli serta 10,23; 8,4; dan 12,21 mm pada bakteri S. typhi. Hasil KLT-Bioautografi dengan eluen n-heksana : etil asetat (5:5)v/v pada fraksi etil asetat dengan Rf 0,45 terdapat zona hambat terhadap S. typhi. Hasil analisis menunjukkan bahwa pemberian perlakuan  ekstrak metanol, fraksi n-heksana dan fraksi etil asetat pada konsentrasi 5, 10, dan 15% berbeda signifikan terhadap kontrol negatif dan positifnya. Fraksi etil asetat daun M. casturi merupakan hasil yang terbaik dalam menghambat bakteri St. aureus, E. coli dan S. typhi. Dengan demikian dapat dikatakan bahwa daun tumbuhan M. casturi berpotensi dalam menghambat pertumbuhan bakteri.
Co-Authors Ahmad Fajri Ahmad Ferry Yeriza Utama Amalia Khairunnisa Amalia Khairunnisa Amalia Khairunnisa, Amalia Arnida Arnida Arnida Arnida Chatarina Umbul Wahyuni Deni Setiawan Desy Aulia Azzahra Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fathur Rahman Fathur Rahman Fery Ramadhan Fitri Fitri Ika Harum Saputri Jehan Azizah Kunti Nastiti Latifah Megasari Latifah Megasari Lilik Koernia Wahidah Mulia Mulia Nani Kartinah Nashrul Wathan Nopiyansyah, Nopiyansyah Normaidah, Normaidah Rahmadati, Erfiza Rezki Agustina Rizqan Azhari Samsuar User Samsuar, Samsuar Samsul Hadi Sindwi Rinanda Sari Siti Nurjanah sunardi sunardi Susanti, Laila Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Utama, Ahmad Ferry Yeriza Wathan, Nasrul Yuli Wahyu Tri Mulyani