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Viogenta, Pratika
Prodi Farmasi FMIPA, Universitas Lambung Mangkurat, BanjarBaru
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Physical Stability and Antioxidant Peel-Off Kefir Mask Arachi (Arachis Hypogaea L) Khairunnisa, Amalia; Kartinah, Nani; Viogenta, Pratika; Mulia, Mulia
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 1: March 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i1.28501

Abstract

The fermented product sector can produce kefir for use in cosmetic preparations. Kefir has weak storage stability and strong antioxidant properties, making it a suitable raw material for cosmetic formulations. The purpose of this study is to determine the best concentration of peanut kefir in Peel-off mask Arachi through antioxidant activity and physical stability during seven cycles of room temperature storage and freeze-thaw (4±2ºC and 40±2ºC). Using the DPPH method based on the IC50 value, the antioxidant activity test was conducted. It was retested after 7 cycles or 28 days. At ambient temperature and freeze-thaw temperature, organoleptic tests, pH, adhesion, and spreadability were conducted in cycles ranging from 0 to 7. The peel-off kefir mask preparations with F1 (0.5%), F2 (1%), and F3 (2%), concentrations created a homogeneous, viscous preparation that was stable at room temperature and freeze-thaw stable for seven cycles, according to the results. In terms of the pH test, the sample showed a drop in pH following storage, stable adhesion for up to seven cycles. However, for F1, the adhesion was not stable in either scenario. With a significant activity category, the formula's antioxidant activity also declines in IC50 values. Therefore, it can be said that even though the peel-off mask preparation changed after storage in a few different ways, it still falls short of the threshold in terms of the physical characteristics of the cosmetic preparation.
Potensi Ekstrak Metanol, Fraksi N-Heksana dan Etil Asetat Daun Kasturi (Mangifera Casturi Kosterm) Terhadap Aktivitasnya Sebagai Anti Bakteri: Potential of Methanol Extract, N-Hexane Fraction and Ethyl Acetate of Kasturi Leaves (Mangifera Casturi Kosterm) for Their Anti-Bacterial Activity Sutomo, Sutomo; Fajri, Ahmad; Viogenta, Pratika; Arnida, Arnida; Wathan, Nasrul
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.8484

Abstract

Salah satu tumbuhan obat yang secara empiris memiliki aktivitas antibakteri adalah kasturi (Mangifera casturi). Tumbuhan M. casturi merupakan salah satu tumbuhan khas Kalimantan. Penelitian ini bertujuan menentukan aktivitas antibakteri ekstrak metanol, fraksi n-heksan dan fraksi etil asetat daun M. casturi terhadap bakteri Staphyloccocus aureus, Eschericia coli, dan Salmonella typhi. Metode yang digunakan pada penelitian ini yakni metode Kirby-bauer dan Bioautografi dengan konsentrasi ekstrak metanol, fraksi n-heksan dan fraksi etil asetat  sebesar 5, 10, dan 15% serta kontrol positif siprofloksasin dan kontrol negatif Na-CMC 0,5%. Hasil menunjukkan bahwa diameter zona hambat ekstrak metanol, fraksi n-heksana dan fraksi etil asetat secara berurutan didapat 14,4; 9,21; dan 14,63 mm pada bakteri St. aureus, 14,43; 16,01; dan 17,21 mm pada bakteri E. coli serta 10,23; 8,4; dan 12,21 mm pada bakteri S. typhi. Hasil KLT-Bioautografi dengan eluen n-heksana : etil asetat (5:5)v/v pada fraksi etil asetat dengan Rf 0,45 terdapat zona hambat terhadap S. typhi. Hasil analisis menunjukkan bahwa pemberian perlakuan  ekstrak metanol, fraksi n-heksana dan fraksi etil asetat pada konsentrasi 5, 10, dan 15% berbeda signifikan terhadap kontrol negatif dan positifnya. Fraksi etil asetat daun M. casturi merupakan hasil yang terbaik dalam menghambat bakteri St. aureus, E. coli dan S. typhi. Dengan demikian dapat dikatakan bahwa daun tumbuhan M. casturi berpotensi dalam menghambat pertumbuhan bakteri.
Innovative Gel Mask A. jiringa (Jack) Nielsen: Effects of HPMC and Palm Stem Starch on Physical Characteristics and Antibacterial Activity Kartinah, Nani; Ulpah, Arnia; Viogenta, Pratika; Khairunnisa, Amalia
Journal of Pharmascience Vol 12, No 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.22397

Abstract

Kulit jengkol (A. jiringa (Jack) Nielsen) merupakan hasil samping pertanian yang belum memiliki nilai ekonomis tinggi, namun diketahui memiliki aktivitas antioksidan dan antibakteri yang kuat. Potensi ini mendasari pengembangan masker gel antijerawat sebagai sediaan topikal kosmetik. Penelitian ini bertujuan untuk mengevaluasi pengaruh kombinasi hidroksipropilmetilselulosa (HPMC) dan pati batang kelapa sawit terhadap karakteristik fisik serta aktivitas antibakteri masker gel A. jiringa terhadap Propionibacterium acnes. Ekstrak diperoleh melalui metode maserasi dan diuji aktivitas antibakterinya pada konsentrasi 0,25%, 0,30%, 0,35%, dan 0,40%. Konsentrasi optimum yang menunjukkan daya hambat tertinggi diformulasikan ke dalam masker gel dengan rasio HPMC:pati pada Formula 1 (1:2), Formula 2 (1:1), dan Formula 3 (2:1). Evaluasi meliputi viskositas, daya sebar, adhesivitas, pH, waktu kering, dan uji difusi sumur terhadap P. acnes. Hasil penelitian menunjukkan bahwa ekstrak A. jiringa 0,40% memiliki aktivitas antibakteri sedang dengan zona hambat 9,82 ± 0,06 mm. Ketiga formula gel memiliki warna cokelat muda, aroma khas minyak atsiri, tekstur halus dan homogen, viskositas antara 46,67 hingga 736,67 cps, daya sebar antara 4,75–8,92 cm, adhesivitas antara 11,52–17,68 detik, waktu kering 5,27–7,57 menit, serta pH berkisar antara 7,30–7,47. Disimpulkan bahwa kombinasi HPMC dan pati batang kelapa sawit mempengaruhi sifat fisik sediaan, namun tidak meningkatkan aktivitas antibakteri A. jiringa dalam sistem gel. Kata Kunci: A. Jiringa, P. Acnes, Antibakteri, Antijerawat, Pati Batang Kelapa Sawit  The peel of Archidendron jiringa (Jack) Nielsen, commonly known as jengkol, is an agricultural by-product with limited economic value but has been reported to possess strong antioxidant and antibacterial properties. This potential supports the development of an anti-acne gel mask as a topical cosmetic preparation. This study aimed to evaluate the effects of combining hydroxypropyl methylcellulose (HPMC) and palm stem starch on the physical characteristics and antibacterial activity of A. jiringa gel masks against Propionibacterium acnes. The extract was obtained through maceration and tested for antibacterial activity at concentrations of 0.25%, 0.30%, 0.35%, and 0.40%. The optimum concentration, which exhibited the highest inhibitory activity, was formulated into gel masks with different HPMC-to-starch ratios: Formula 1 (1:2), Formula 2 (1:1), and Formula 3 (2:1). Evaluations included viscosity, spreadability, adhesiveness, pH, drying time, and antibacterial activity using the well diffusion method against P. acnes. The results showed that the 0.40% A. jiringa extract exhibited moderate antibacterial activity with an inhibition zone of 9.82 ± 0.06 mm. All three gel formulations had a light brown color, a characteristic essential oil aroma, a smooth and homogeneous texture, viscosities ranging from 46.67 to 736.67 cps, spreadability between 4.75–8.92 cm, adhesiveness ranging from 11.52 to 17.68 seconds, drying time from 5.27 to 7.57 minutes, and pH values between 7.30 and 7.47. It was concluded that the combination of HPMC and palm stem starch influenced the physical properties of the gel formulations but did not enhance the antibacterial activity of A. jiringa in the gel system.
Edukasi Penerapan Teknologi Fermentasi melalui Pembuatan Kefir dan Yogurt Khairunnisa, Amalia; Pratika Viogenta; Nani Kartinah; Arnida Arnida; Sutomo Sutomo; Fadlilaturrahmah Fadlilaturrahmah
Jurnal Nusantara Berbakti Vol. 2 No. 4 (2024): Oktober : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v2i3.411

Abstract

Fermentation technology can increase added value to agricultural, food and other products. Through fermentation, raw materials can be converted into products with higher selling value, such as cheese, yogurt, tempeh, wine, beer, and so on. Many fermented products are beneficial for health, for example kefir and yogurt which contain good probiotics. for digestion. Kefir is a type of fermented milk whose manufacture uses various microorganisms to produce lactic acid products with by-products such as ethanol, free fatty acids and acetaldehyde. Kefir is made by adding yeast which contains many microorganisms from the lactic acid bacteria and yeast groups, while yogurt is fermented milk with lactic acid bacteria (LAB).  This service activity aims to increase people' knowledge and skills regarding the application of fermentation technology, starting from the meaning of fermentation, fermentation methods to high-value products produced from the fermentation process. In this activity, socialization activities were carried out regarding the development of fermentation technology, especially kefir and cow's milk yogurt, as well as practices on how to make it among the residents of Balitra Jaya Permai Loktabat Utara. The results show an increase in residents' knowledge and skills regarding fermentation through pretest and posttest activities as well as practical activities.
Co-Authors Ahmad Fajri Ahmad Ferry Yeriza Utama Amalia Khairunnisa Amalia Khairunnisa Amalia Khairunnisa, Amalia Arnida Arnida Chatarina Umbul Wahyuni Deni Setiawan Desy Aulia Azzahra Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fathur Rahman Fathur Rahman Fery Ramadhan Fitri Fitri Ika Harum Saputri Jehan Azizah Kunti Nastiti Latifah Megasari Latifah Megasari Lilik Koernia Wahidah Mulia Mulia Nani Kartinah Nashrul Wathan Nopiyansyah, Nopiyansyah Normaidah, Normaidah Rahmadati, Erfiza Rezki Agustina Rizqan Azhari Samsuar User Samsuar, Samsuar Samsul Hadi Sindwi Rinanda Sari Siti Nurjanah sunardi sunardi Susanti, Laila Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Ulpah, Arnia Utama, Ahmad Ferry Yeriza Wathan, Nasrul Yuli Wahyu Tri Mulyani