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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Biota Majalah Obat Tradisional Jurnal Surya Medika ALCHEMY Jurnal Penelitian Kimia JFL : Jurnal Farmasi Lampung Journal of Midwifery and Nursing Jurnal Kesehatan Journal of Multidisciplinary Applied Natural Science Jurnal Inovasi Pembangunan Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Jurnal Bakti Untuk Negeri Safari : Jurnal Pengabdian Masyarakat Indonesia Jurnal Nusantara Berbakti Borneo Journal of Pharmacy Journal of Pharmascience
Viogenta, Pratika
Prodi Farmasi FMIPA, Universitas Lambung Mangkurat, BanjarBaru
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Cox2 Inhibitor Test Of Limpasu (Baccaurea Lanceolata) Using Computation Method Samsul Hadi; Nashrul Wathan; Deni Setiawan; Pratika Viogenta; Kunti Nastiti
Journal of Midwifery and Nursing Vol. 5 No. 3 (2023): September: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v5i3.4104

Abstract

The use of anti-inflammatory drugs with the COX-2 method is starting to develop tolerance, so that drugs circulating in the community now cause various kinds of complaints, namely inhibition of blood clotting and stomach ulcers. Therefore, the purpose of this study was to screen natural product compounds that have potential as COX-2 inhibitors. The materials used are compounds contained in B.lanceolata and COX-2 enzymes with code 3ln1 obtained from the RCSB database, the equipment used is a windows laptop with PLANT and discover studio software, the method used in this study is a computational study using docking software . The results in this study were that the docking score of B. lanceolata was higher than the native ligand, so the effectiveness was weaker than the native ligand, the docking scores obtained were as follows: Epidihydrotutin (-50.243); Sapidolide A (-51052); Melatonin (-53039); 6'-O-Vanilloylisotachioside (-60.910) and 6'-O-Vanilloyltachioside (-61.131). In conclusion, 6'-O-Vanilloyltachioside is a potential compound as a COX-2 inhibitor from B.lanceolata.
Peel-off Kefir Mask Arachi (Arachis hypogaea L.): Characterization and Antioxidant Activity Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Fathur Rahman; Mulia Mulia
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2597

Abstract

This study aims to determine the best formulation for the peel-off mask Arachi or peanut (Arachis hypogaea L). Arachis hypogaea kefir as an active ingredient is added with variations in the concentration of F1 (0.5%) and F2 (2%) (w/v). Organoleptic tests, homogeneity, dry time, and pH were carried out on the peel-off mask that had been made. Antioxidant test (DPPH methods) was performed on masks F1 and F2. The results showed that the peel-off mask of A. hypogaea kefir had the best antioxidant activity at a concentration of 2% (F2) kefir with an IC50 value of 1.865 ppm and was very active. The characteristics of the peel-off mask have good physical stability, proven by not experiencing a change in color, odor, being homogeneous, having good dispersion power, and having a dry time ranging from 10-23 minutes. The pH value of the peel-off mask preparation is 4.52, and it is appropriate with SNI and the pH balance of normal human skin. The peel-off mask of A. hypogaea kefir can be produced because has good physical stability and antioxidant activity.
Pemberian Makanan Tambahan Melalui Olahan Jamu Dan Nugget Kelor Sebagai Upaya Pencegahan Stunting Amalia Khairunnisa; Sutomo Sutomo; Nani Kartinah; Pratika Viogenta; Rizqan Azhari
SAFARI :Jurnal Pengabdian Masyarakat Indonesia Vol. 3 No. 4 (2023): Oktober: Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/safari.v3i4.850

Abstract

Stunting is a state of malnutrition and causes delays in brain development and child development in the first 1000 days of life. One of the factors that causes stunting is a lack of nutritional intake in infants or toddler mothers. The purpose of this service is to provide education and practice regarding supplementary feeding through moringa leaves such as nuggets and moringa herbs in Mandiangin Barat village, South Kalimantan. The method used in this service activity is in the counseling about the use of Moringa leaves as processed nutritious food and drinks, as well as the practice of processing Moringa nuggets and herbs. The results of these activities can be concluded that the community in Mandiangin Barat village has developed a level of understanding about supplementary feeding and can process into food and drinks that have nutritional value as an effort to prevent stunting rates in the village.
Program Wadai Bingka (Wadah Kami Belajar Meningkatkan Kesehatan): Dampak Pernikahan Dini, Kesehatan Reproduksi Dan Alat Kontrasepsi Nani Kartinah; Pratika Viogenta; Sutomo Sutomo; Amalia Khairunnisa; Rezki Agustina
SAFARI :Jurnal Pengabdian Masyarakat Indonesia Vol. 3 No. 4 (2023): Oktober: Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/safari.v3i4.919

Abstract

The negative impact of early marriage is the increased risk of maternal and child mortality, miscarriage, stunting in children, and poor reproductive health conditions. Wadai Bingka activities aim to increase public knowledge about the right marriage age, the importance of maintaining reproductive health and the use of contraceptives. The method used is in the form of education using an extension system, booklets, teaching aids and animated videos. There were 24 participants. Evaluation of activities is carried out by comparing the score values obtained by participants before the implementation of the activity (pre-test) and after the implementation of the activity (posttest). Based on the evaluation results, changes in participants' knowledge for good criteria increased by 84%, medium criteria decreased by 54%, and bad criteria decreased by 100%. It can be concluded that Wadai Bingka's service activities have a good impact as evidenced by an increase in community knowledge.
Antioxidant Assay of Kefir Peanut (Arachis hypogaea L.) with Variations in Concentration and Fermentation Time Viogenta, Pratika; Khairunnisa, Amalia; Kartinah, Nani; Rahmadati, Erfiza
Majalah Obat Tradisional Vol 29, No 3 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.87814

Abstract

Kefir is a processed beverage produced through pasteurized milk fermentation using a starter from kefir grains. These grains contain groups of lactic acid bacteria and yeast. Peanuts can be used as a raw material for kefir products and Arachis hypogaea L. has antioxidant activity due to a high nutritional content namely vegetable oil, protein, minerals, and essential fatty acids. This study aimed to determine the highest antioxidant activity with variations in concentration and time fermentation of peanut kefir (Arachis hypogaea L.). This research on the antioxidant activity test method used the DPPH method with UV-Vis spectrophotometry. The results of testing the antioxidant activity of peanut kefir with variations in the concentration of kefir grains of 0%, 1%, 2%, and 3% had IC50 values of 64.929 ppm, 57.675 ppm, 54.742 ppm, and 51.870 ppm, respectively. The one-way ANOVA test showed a significant difference between the IC50 value and the concentration of kefir grains. The highest antioxidant in 3% concentration determined the fermentation time with 0, 12, 24, 36, 48, and 60 hours variations. The results of testing the antioxidant activity of kefir peanut with variations in the fermentation time it was had IC50 values of 64.319 ppm respectively, 62.609 ppm, 59.376 ppm, 56.321 ppm, 51.870 ppm, and 51.384 ppm. The one-way ANOVA test results showed no significance in the 0 with 12 hours completion time and 48 with 60 hours. The research results on peanut kefir show that kefir grains of 3% and the duration of fermentation for 48 hours have strong antioxidant activity.
The Characterization of Capsule Shell from Acid-Hydrolyzed Palm Oil Starch Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Desy Aulia Azzahra
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 1 (2025): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.1.93550.72-81

Abstract

Acid hydrolysis of palm trunk starch can increase the amylose content in starch, providing a stronger and more stable film. This study aims to obtain the best-modified starch concentration ratio with hydroxypropyl methylcellulose (HPMC) and identify their characteristics. Modifying palm trunk starch was conducted with an acetic buffer using CH3COONa and CH3COOH, decolorizing starch with activated carbon. Manufacturing a capsule shell was performed with weight ratio variations of modified starch and HPMC 1:1 (F1), 2:1 (F2), and 3:1 (F3). All formulations produced firm and elastic capsule shells. The capsule products were consistent in an average weight of F1 (0.10 g), F2 (0.11 g), and F3 (0.14 g). The average disintegration test results were F1 (10 minutes, 27.57 seconds), F2 (6 minutes, 47.06 seconds), and F3 (4 minutes, 34.24 seconds). Tensile strength results were F1 (2.147 MPa), F2 (2.565 MPa), and F3 (2.159 MPa). Fourier Transform Infrared (FTIR) results showed a vibration at a wavenumber of 1560 cm-1 corresponding to the characteristic fingerprint of the C–O vibration stretching in the capsule shell made from starch modified by HPMC. The concentration of modified starch affects the capsule shell’s characteristics, showing that capsule shell F2 (2:1) has the best formulation.
Physical Stability and Antioxidant Peel-Off Kefir Mask Arachi (Arachis Hypogaea L) Khairunnisa, Amalia; Kartinah, Nani; Viogenta, Pratika; Mulia, Mulia
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 1: March 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i1.28501

Abstract

The fermented product sector can produce kefir for use in cosmetic preparations. Kefir has weak storage stability and strong antioxidant properties, making it a suitable raw material for cosmetic formulations. The purpose of this study is to determine the best concentration of peanut kefir in Peel-off mask Arachi through antioxidant activity and physical stability during seven cycles of room temperature storage and freeze-thaw (4±2ºC and 40±2ºC). Using the DPPH method based on the IC50 value, the antioxidant activity test was conducted. It was retested after 7 cycles or 28 days. At ambient temperature and freeze-thaw temperature, organoleptic tests, pH, adhesion, and spreadability were conducted in cycles ranging from 0 to 7. The peel-off kefir mask preparations with F1 (0.5%), F2 (1%), and F3 (2%), concentrations created a homogeneous, viscous preparation that was stable at room temperature and freeze-thaw stable for seven cycles, according to the results. In terms of the pH test, the sample showed a drop in pH following storage, stable adhesion for up to seven cycles. However, for F1, the adhesion was not stable in either scenario. With a significant activity category, the formula's antioxidant activity also declines in IC50 values. Therefore, it can be said that even though the peel-off mask preparation changed after storage in a few different ways, it still falls short of the threshold in terms of the physical characteristics of the cosmetic preparation.
Potensi Ekstrak Metanol, Fraksi N-Heksana dan Etil Asetat Daun Kasturi (Mangifera Casturi Kosterm) Terhadap Aktivitasnya Sebagai Anti Bakteri: Potential of Methanol Extract, N-Hexane Fraction and Ethyl Acetate of Kasturi Leaves (Mangifera Casturi Kosterm) for Their Anti-Bacterial Activity Sutomo, Sutomo; Fajri, Ahmad; Viogenta, Pratika; Arnida, Arnida; Wathan, Nasrul
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.8484

Abstract

Salah satu tumbuhan obat yang secara empiris memiliki aktivitas antibakteri adalah kasturi (Mangifera casturi). Tumbuhan M. casturi merupakan salah satu tumbuhan khas Kalimantan. Penelitian ini bertujuan menentukan aktivitas antibakteri ekstrak metanol, fraksi n-heksan dan fraksi etil asetat daun M. casturi terhadap bakteri Staphyloccocus aureus, Eschericia coli, dan Salmonella typhi. Metode yang digunakan pada penelitian ini yakni metode Kirby-bauer dan Bioautografi dengan konsentrasi ekstrak metanol, fraksi n-heksan dan fraksi etil asetat  sebesar 5, 10, dan 15% serta kontrol positif siprofloksasin dan kontrol negatif Na-CMC 0,5%. Hasil menunjukkan bahwa diameter zona hambat ekstrak metanol, fraksi n-heksana dan fraksi etil asetat secara berurutan didapat 14,4; 9,21; dan 14,63 mm pada bakteri St. aureus, 14,43; 16,01; dan 17,21 mm pada bakteri E. coli serta 10,23; 8,4; dan 12,21 mm pada bakteri S. typhi. Hasil KLT-Bioautografi dengan eluen n-heksana : etil asetat (5:5)v/v pada fraksi etil asetat dengan Rf 0,45 terdapat zona hambat terhadap S. typhi. Hasil analisis menunjukkan bahwa pemberian perlakuan  ekstrak metanol, fraksi n-heksana dan fraksi etil asetat pada konsentrasi 5, 10, dan 15% berbeda signifikan terhadap kontrol negatif dan positifnya. Fraksi etil asetat daun M. casturi merupakan hasil yang terbaik dalam menghambat bakteri St. aureus, E. coli dan S. typhi. Dengan demikian dapat dikatakan bahwa daun tumbuhan M. casturi berpotensi dalam menghambat pertumbuhan bakteri.
Edukasi Penerapan Teknologi Fermentasi melalui Pembuatan Kefir dan Yogurt Khairunnisa, Amalia; Pratika Viogenta; Nani Kartinah; Arnida Arnida; Sutomo Sutomo; Fadlilaturrahmah Fadlilaturrahmah
Jurnal Nusantara Berbakti Vol. 2 No. 4 (2024): Oktober : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v2i3.411

Abstract

Fermentation technology can increase added value to agricultural, food and other products. Through fermentation, raw materials can be converted into products with higher selling value, such as cheese, yogurt, tempeh, wine, beer, and so on. Many fermented products are beneficial for health, for example kefir and yogurt which contain good probiotics. for digestion. Kefir is a type of fermented milk whose manufacture uses various microorganisms to produce lactic acid products with by-products such as ethanol, free fatty acids and acetaldehyde. Kefir is made by adding yeast which contains many microorganisms from the lactic acid bacteria and yeast groups, while yogurt is fermented milk with lactic acid bacteria (LAB).  This service activity aims to increase people' knowledge and skills regarding the application of fermentation technology, starting from the meaning of fermentation, fermentation methods to high-value products produced from the fermentation process. In this activity, socialization activities were carried out regarding the development of fermentation technology, especially kefir and cow's milk yogurt, as well as practices on how to make it among the residents of Balitra Jaya Permai Loktabat Utara. The results show an increase in residents' knowledge and skills regarding fermentation through pretest and posttest activities as well as practical activities.
Isolasi Jamur Endofitik Rumput Mutiara (Hedyotis corymbosa (L.) Lamk.) dan Analisis Potensi Sebagai Antimikroba Pratika Viogenta; Siti Nurjanah; Yuli Wahyu Tri Mulyani
Journal of Pharmascience Vol. 7 No. 1 (2020): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i1.8076

Abstract

ABSTRAK Jamur endofit merupakan jamur yang hidup di dalam jaringan atau organ tanaman yang tidak bersifat patogen. Jamur ini dapat menghasilkan beberapa zat yang sama seperti tanamannya.  Rumput mutiara (Hedyotis corymbosa (L.) Lamk)  merupakan jenis rumput liar yang biasa hidup di tanah lembab. Tujuan penelitian ini adalah untuk mengetahui keanekaragaman mikroba endofit rumput mutiara. Metode dari penelitian ini meliputi isolasi jamur endofit dari batang, daun, akar, bunga rumput mutiara,  identifikasi jamur yang berhasil diisolasi, pengukuran diameter laju pertumbuhan jamur endofit dan uji daya hambat antimikroba dari jamur endofit. Hasil penelitian didapatkan tujuh jenis jamur endofit yang berhasil diisolasi dari rumput mutiara (batang, daun, akar dan bunga). Setelah diindentifikasi ketujuh jenis kapang, yaitu 2 jenis dari genus Aspergillus yaitu A. niger dan A. parasiticus yang berhasil diisolasi dari akar, batang, daun rumput mutiara, Penicillium berasal dari akar rumput mutiara, Geotrchihum dari batang, Chrysosporium dari daun, Rhizoctonia  dan Phytophthora dari bunga. Pada ketujuh jamur endofit ini fase lag terjadi hari pertama dan fase eksponensial terlihat pada hari kedua sampai hari ketujuh. Aspergillus niger memiliki daya hambat terhadap E.coli, St. aureus, Sh. disentriae,dan P.aeruginosa masing-masing 9.95mm, 8.96mm, 10.51mm,  dan 9.26mm. Chrysosporium dan Phytophthora mengahambat C. albicans sebesar 11.3mm dan 3.63mm.  Kata Kunci: Rumput mutiara, jamur endofit, antimikroba. ABSTRACT Endophytic fungi are fungi that live in plant tissues or organs that are not pathogenic. This fungus can produce some of the same substances as the plant. Pearl grass (Hedyotis corymbosa (L.) Lamk) is a type of weed that normally lives in moist soil. The purpose of this study was to determine the diversity of endophytic pearl grass microbes. The methods of this study include the isolation of endophytic fungi from stems, leaves, roots, and flowers  of pearl grass, identification, measurement of the diameter of endophytic fungi growth rate and antimicrobial inhibition test of endophytic fungi. The results showed seven types of endophytic fungi that were isolated from pearl grass. After identifying the seven types of molds, namely 2 types of the genus Aspergillus namely A.niger and A.parasiticus which were successfully isolated from roots, stems, pearl grass leaves, Penicillium derived from pearl grass roots, Geotrchihum from the stems, Chrysosporium from leaves, Rhizoctonia and Phytophthora from flowers. In these seven endophytic fungi the lag phase occurs the first day and the exponential phase is seen on the second day to the seventh day. Aspergillus niger has inhibitory properties against E.coli, St.aureus, Sh.disentriae, and P.aeruginosa 9.95mm, 8.96mm, 10.51mm and 9.26mm, respectively. Chrysosporium and Phytophthora inhibit C. albicans by 11.3mm and 3.63mm. Keywords: Pearl grass, endophytic fungus, antimicrobial
Co-Authors Ahmad Fajri Ahmad Ferry Yeriza Utama Amalia Khairunnisa Amalia Khairunnisa Amalia Khairunnisa, Amalia Arnida Arnida Chatarina Umbul Wahyuni Deni Setiawan Desy Aulia Azzahra Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fathur Rahman Fathur Rahman Fery Ramadhan Fitri Fitri Ika Harum Saputri Jehan Azizah Kunti Nastiti Latifah Megasari Latifah Megasari Lilik Koernia Wahidah Mulia Mulia Nani Kartinah Nashrul Wathan Nopiyansyah, Nopiyansyah Normaidah, Normaidah Rahmadati, Erfiza Rezki Agustina Rizqan Azhari Samsuar User Samsuar, Samsuar Samsul Hadi Sindwi Rinanda Sari Siti Nurjanah sunardi sunardi Susanti, Laila Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Ulpah, Arnia Utama, Ahmad Ferry Yeriza Wathan, Nasrul Yuli Wahyu Tri Mulyani