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All Journal Global Medical and Health Communication Padjadjaran Journal of Dentistry Journal of Medicine and Health Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Abdimas Kartika Wijayakusuma Journal of Health and Dental Sciences Jurnal Medika: Medika Journal of Medicine and Health
Florence Meliawaty
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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PROSPECTIVE USE OF REUNDEU LEAVES (Staurogyne elongata) ON INFLAMMATORY MACROPHAGES IN SKIN EXCISION WOUND Meliawaty, Florence; Nur Robbani , Mistli; Endrowahyudi, Hartanto; Reni Yuslianti , Euis
Journal of Health and Dental Sciences Vol. 5 No. 2 (2025): Journal of Health and Dental Sciences
Publisher : Fakultas Kedokteran Gigi Unjani

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Abstract

Healing of skin excision wounds involves complex stages, with inflammatory macrophages playing a key role in regulating the inflammatory response and tissue regeneration. Staurogyne elongata (Reundeu leaves), a medicinal plant native to Indonesia, contains bioactive compounds such as flavonoids, saponins, steroids, triterpenoids, and polyphenols, which exhibit antioxidant and antibacterial properties. This literature review aimed to explore the prospective role of S. elongata in modulating inflammatory macrophage activity during skin excision wound healing. Articles published within the last 10 years were retrieved from ProQuest, PubMed, ScienceDirect, and Science Publishing Group databases. The scientific implication is that Staurogyne elongata (Reundeu leaves) has potential therapeutic effects on skin excision wound healing by modulating inflammatory macrophage activity. Specifically, its bioactive compounds may promote the transition of macrophages from a pro-inflammatory (M1) to an anti-inflammatory (M2) state, leading to reduced inflammation and enhanced tissue regeneration. The results suggest that S. elongata could be developed as a natural, cost-effective adjunct treatment to improve wound healing outcomes, highlighting the need for further experimental validation, clinical studies, and pharmaceutical formulation development. DOI : 10.54052/jhds.v5n2.p213-226
Temperature and holding time of instrument sterilization as an infection control of odontectomy Meliawaty, Florence; Mangundjaja, Sunardhi; Hardjawinata, Karlina
Padjadjaran Journal of Dentistry Vol 23, No 1 (2011): March 2011
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3763.687 KB) | DOI: 10.24198/pjd.vol23no1.14059

Abstract

Odontectomy should be performed aseptically. The goal of sterilization is the complete killing of all forms of microbial life including bacterial spores on the items being processed. Biologic monitoring provides the main guarantee of sterilization. The aim of this study was to find the interrelation of the temperature and the holding time of instrument sterilization as an infection control for the successful of lower molars odontectomy. This experimental laboratory study was conducted at the Oral Maxillofacial Surgery Department in the Hasan Sadikin General Hospital Bandung and at the Microbiology Laboratory Faculty of Dentistry, Universitas Padjadjaran, Jatinangor. The Protocol was performed in three methods of sterilization: dry heat with oven and ozone, dry heat with oven and infrared (125)C for 15 minutes), both were monitored by Bacillus atrophaeus as the biologic indicators, and autoclavization (121" C for 15 minutes) with Geobaciflus stearothermophilus as the biological monitoring, with 17 times repetition. After sterilization, all of the indicators were cultured on Nutrient Agar Plate (NAPS), and the subsequent growth was assessed. The colony forming units (CFUs) were counted by Stuart Electric Bacteria Colony Counter. Adequate positive and negative controls were used in every cycle. The results showed that after autoclavization, all spores were killed. In comparison with dry heat in the oven, there were still CFUs on the NAPs, but no colonies grow after 3 repetitions by oven and infrared. Heating in oven and ozone could only reduce the spore numbers, even after repeating 5 times. The reduction of the CFUs was greater in more repetition. According to the statistical analysis, the differences were significant. This study concluded that sterilization by oven and infrared will be achieved after 3 holding times (30-35 minutes) and dry heat with oven and ozone could only act as a germicide. In autoclavization, all of Geobacillus steorothermophilus have been killed.
DENTIGEROUS CYST IN CHILDREN: A RARE CASE REPORT Meliawaty, Florence
Journal of Health and Dental Sciences Vol. 3 No. 3 (2024): Journal of Health and Dental Sciences
Publisher : Fakultas Kedokteran Gigi Unjani

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Abstract

Dentigerous cysts are growths of the jaw's epithelial lining that develop from the dental follicle of unerupted teeth. These cysts are usually found during routine radiography exams, associated with immature teeth. Dentigerous cysts typically don't cause symptoms unless they get big enough to swell. Third, molars and maxillary canines are frequently associated with most dentigerous cysts. A diagnosis is made based on histopathological, radiological, and clinical findings. We describe an instance of a dentigerous cyst that was connected to two immature mandibular premolar teeth. This rare case report discusses the treatment of a dentigerous cyst in the lower premolar region of the left mandible. Under local anesthesia, the patient had surgical treatment that included the removal of two primary teeth and enucleation of the cyst. The evaluation revealed that one week after surgery, the recovery was complete. DOI : 10.54052/jhds.v3n3.p273-280
Co-Authors Adinugraha, Irham M. Akhirul Kahfi Syam Ani Melani Maskoen Asih Rahaju Choirunnisa, Tias Djohan, Frita Ferlita Shafri Endrowahyudi, Hartanto Faramayudha, Fahrauk Frita Ferlita Shafri Djohan Handayani, Dewi Ratih Irfianti, Isti Irsyad, Widya Isnaeni, Rheni Safira Jeffrey Jeffrey Juliastuti, Henny Karlina Hardjawinata, Karlina Khaerunnisa, Rahmadaniah Nasroen, Saskia Lenggogeni Nur Robbani , Mistli Prasdiaz, Putri Indriani Putriani, Wivda Rachman Ardan, Rachman Rahaju, Asih Rakhmat, Iis Inayati Ramdhani, Muhamad Syahrul Reni Yuslianti , Euis Sabirin, Indah Puti R. Soraya Riyanti, Soraya Sunardhi Mangundjaja, Sunardhi Suntana, Mutiara Sukma Tichvy Tammama, Tichvy Yuslianti, Euis Reni