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KEAMANAN PENGGUNAAN OBAT PADA KEHAMILAN DI RUMAH SAKIT SWASTA YOGYAKARTA Sari, Chynthia Pradiftha; Hanifah, Suci; Febrianti, Yosi; Sari, Azmi Fahma; Dwirahmania, Pipit
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2485

Abstract

Pregnancy is a special physiological condition in which the use of medication is often unavoidable. However, the risks of teratogenicity and drug safety require careful evaluation to minimize risks to both mother and fetus. This study aims to evaluate the safety of drug use based on FDA (Food and Drug Administration) categories in pregnant inpatients at a private hospital in Yogyakarta. The study uses a descriptive observational method with a cross- sectional design, analyzing 141 inpatient medical records from 2022. The analyzed data includes patient demographics, diagnoses, drug safety, and dosages. Inclusion criteria were pregnant inpatients treated with or without pregnancy emergencies; exclusion criteria were patients giving birth or experiencing abortion. Descriptive results (using Microsoft Excel) showed most pregnant inpatients were aged 20-35 years (80.14%), hospitalized during the first trimester (49.65%), had no comorbidities (90.07%), no emergency pregnancy conditions (82.27%), and a length of stay under 4 days (72.34%). The most common diagnosis was hyperemesis gravidarum (41.84%), with predominant use of multivitamins (16.18%) and antiemetics (14.91%). The safety of drugs in inpatients was categorized as A (18.80%), B (34.34%), C (36.86%), D (2.26%), and N (6.77%), with appropriate dosage usage (96,30%). The study concludes that drug use was dominated by category C, and no use of category X drugs was found. The most used drugs were folic acid multivitamins and iron supplements for increasing blood levels.
Effectiveness of delivery mode of pharmacist intervention to improve medication adherence and clinical outcomes in people with depression: a systematic review Febrianti, Yosi; Sari, Ika Puspita; Widayanti, Anna Wahyuni; Setiyawati, Diana
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.25537

Abstract

Depression is a treatable mental health condition with various medication options available. For patients with major depressive disorder (MDD), adherence to antidepressants is essential for effective treatment. However, low medication adherence remains a significant challenge, particularly in individuals with depression. Pharmacists play a crucial role in managing these patients. This systematic review evaluated the impact of pharmacist-led interventions, focusing on the effectiveness of delivery modes (in-person vs. online) in improving medication adherence and clinical outcomes for patients with depression. Randomised and non-randomised controlled trials were included. Data were sourced from PubMed, Scopus, ScienceDirect, and Google Scholar using keywords such as "pharmacist intervention," "education," "medication adherence," "depression," and "medication compliance." Three reviewers independently screened and selected articles, and methodological quality was assessed using the Joanna Briggs Institute Randomized Controlled Trial Checklist. From an initial pool of 791 publications, 364 underwent a comprehensive review, and 14 met the inclusion criteria. The most successful interventions were those conducted face-to-face (83%), compared to those conducted through video and phone calls (16%). However, neither method could improve the severity of depression significantly. Pharmacist interventions can enhance patient adherence to antidepressant medication in patients with depression. Compared to virtual methods, face-to-face techniques are more effective at improving adherence. However, they were not able to improve the symptoms of depression.