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henny Mulyani
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PROSES SOLUTION TREATMENT DAN PENGARUHNYA TERHADAP SIFAT MEKANIK DAN STRUKTUR MIKRO PADUAN Zr-Ti-(x)Al PADA APLIKASI SCREW DENTAL IMPLANT Mulyani, Henny; Nurrobi, Mohamad Iqbal; Prajitno, Djoko Hadi
Jurnal TEDC Vol 17 No 3 (2023): JURNAL TEDC
Publisher : UPPM Politeknik TEDC Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70428/tedc.v17i3.757

Abstract

This research was to investigate the microstructure and mechanical properties of ternary alloys Zr-10Ti-(x)Al (x = 0, 2, 4 wt.%) through solution treatment process with temperature variations 900℃, 1000℃, and 1100℃. The results indicated that α and α' phase existed in Zr-10Ti-(x)Al alloys. The hardness of the Zr-10Ti-4Al alloys in 1100℃ treatment was significantly increased because of solution treatment process, from 382.462 HV (0% Al), 403.304 HV (2% Al), and 465.68 HV (4% Al) to 386.066 HV (0% Al), 452.244 HV (2% Al), and 494.016 HV (4% Al). The addition of Al will increase the hardness of alloy because of strengthening mechanism beside the formation of intermetallic compound, the solution treatment process will increase the percentage of β phase and generated the phase transformation into α' which increased the alloy’ mechanical properties. In conclusion, Zr-10Ti-4Al alloy will be a great potential material for dental implant biomaterial.
Clinical characteristics of maxillofacial fracture patients in Dr. M. Djamil General Hospital Padang Hafiz, Al; Maidatuz Zahra, Agnesia; Mulyani, Henny; Huriyati, Effy; Revilla, Gusti; Zhuhra, Rahma Tsania
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.661

Abstract

Background: Maxillofacial fracture consists of several types of fractures depending on their location. Traffic accidents are the most common cause of these cases. The choice of management given in maxillofacial fractures is divided into immediate and planned delayed management, depending on the condition of the injured tissue. Purpose: To describe the clinical characteristics of maxillofacial fracture in the Department of Otorhinolaryngology Faculty of Medicine Universitas Andalas/Dr. M. Djamil General Hospital Padang, in 2020 to 2022. Method: A descriptive study with retrospective approach. The study was conducted by collecting data from the medical record section by using a total sampling technique (59 patients) from 2020 to 2022. Result: The highest cause was traffic accidents (49.2%), the most common findings were nasal bone fracture (44.1%), with operative management (82.4%). Conclusion: Maxillofacial fractures were most commonly experienced by the young age group and caused by traffic accidents, therefore driving safety and driver compliance should be more emphasized. Keywords: maxillofacial fracture, ORIF (Open Reduction Internal Fixation), septorhinoplasty, septoplasty, rhinoplasty ABSTRAK Latar belakang: Fraktur maksilofasial terdiri dari beberapa jenis fraktur tergantung lokasinya. Kecelakaan lalu lintas menjadi penyebab tersering dari kasus ini. Pemilihan tatalaksana yang diberikan pada fraktur maksilofasial dibagi menjadi tatalaksana segera dan tatalaksana lanjutan terencana, tergantung dari kondisi jaringan yang terluka. Tujuan: Untuk mengetahui karakteristik klinis pasien fraktur maksilofasial di Departemen THT-BKL FK Unand/RSUP Dr. M. Djamil Padang, dari 2020 sampai 2022. Metode: Penelitian ini bersifat deskriptif dengan pendekatan retrospektif. Penelitian dilakukan dengan pengambilan data di bagian rekam medik dengan teknik total sampling dan didapatkan sampel sebanyak 59 pasien pada tahun 2020 sampai 2022. Hasil: kelompok usia paling sering adalah 16-30 tahun (54.2%), dengan jenis kelamin terbanyak adalah laki-laki (76.3%), penyebab tersering adalah kecelakaan lalu lintas (4.2%), jenis fraktur tersering adalah fraktur tulang hidung (44.1%), dan tatalaksana paling sering adalah tatalaksana operatif (82.4%) Kesimpulan: Fraktur maksilofasial paling sering dialami oleh kelompok usia remaja dan disebabkan kecelakaan lalu lintas, oleh karena itu keselamatan dan kepatuhan berkendara perlu lebih diperhatikan dan ditingkatkan. Kata kunci: fraktur maksilofasial, ORIF (Open Reduction Internal Fixation), septorinoplasti, septoplasti, rinoplasti
Programmed Death-Ligand 1 (PD-L1) and Ki-67 Labeling Index: Correlation with Tumor Grade and Recurrence Wildanur, Sri; Yenita; Mulyani, Henny
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i1.1165

Abstract

Background: Meningiomas are common primary brain tumors with variable clinical behavior. While most are benign, a subset exhibits aggressive characteristics and a high recurrence rate. This study aimed to investigate the association of Programmed Death-Ligand 1 (PD-L1) and Ki-67 labeling index with histopathological grade and recurrence in meningioma. Methods: A retrospective study was conducted on 139 cases of meningioma diagnosed between January 2020 and December 2023. PD-L1 expression was evaluated using immunohistochemistry (IHC) and scored using the combined positive score (CPS). Ki-67 labeling index was determined as the percentage of tumor cells with positive nuclear staining. The association of PD-L1 and Ki-67 with histopathological grade and recurrence was analyzed. Results: PD-L1 expression was positive in 66.7% of cases and was significantly associated with recurrence (p = 0.006). A higher Ki-67 labeling index (>4%) was observed in 68.9% of cases and was also significantly associated with recurrence (p = 0.013). No significant association was found between PD-L1 expression or Ki-67 labeling index and histopathological grade. Conclusion: PD-L1 expression and Ki-67 labeling index may serve as potential prognostic markers for predicting recurrence in meningioma. Further studies are needed to validate these findings and explore their potential therapeutic implications.
The Histological Features of Schwannoma in Frozen Section: A Case Report Safnita, Dewi; Mulyani, Henny
Frontiers on Healthcare Research Vol. 1 No. 1 (2024)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v1.n1.p24-30.2024

Abstract

Background: Intraoperative diagnosis by cytological and frozen section procedures is needed in some cases including peripheral nerve specimens. The results of the cytological evaluation and frozen sections can be relied upon to guide the surgeon in making intraoperative decisions. The pathologist provides information on gross and microscopic findings that correlate with the clinical, and radiological. Although the cytology and frozen section diagnosis approach has been carried out in a multidisciplinary manner, there are still limitations in the intraoperative diagnosis of peripheral nerve specimens. Limitations in this procedure can be overcome by understanding and analyzing possible errors and pitfalls during the procedure thereby increasing the accuracy of the diagnosis. Case report: Schwannoma is a nerve sheath tumor consisting of neoplastic cells with Schwann cell differentiation that generally originates from peripheral nerves in the skin and subcutaneous tissue of the head and neck or along the flexor surfaces of the extremities. More than 90% of schwannomas are solitary and sporadic lesions that can affect any age but with a peak incidence in the fourth to sixth decades of life and there is no racial or gender predisposition. Conclusion: Schwannomas often appear as asymptomatic masses or incidental findings. Intraoperative frozen section pathological diagnosis can be used in determining subsequent surgical management.
Co-Authors Aden, Kuntum Annisa Tiara Al Hafiz Aswiyanti Asri Daan Khambri Djoko Hadi Prajitno Effy Huriyati Eka Fithra Elfi, Eka Fithra Erlina Rustam Etriyel Myh Fedrivia, Rannia Gusti Revilla Hafni Bachtiar Hardian, Sonny Husna Yetti Indradmojo, Christyaji Mahendra, Muhammad Isa Maidatuz Zahra, Agnesia Mayorita, Pamelia Nindita, Priska Audina Novianti, Hera Noza Hilbertina, Noza Nur, Aswaty Nurhayati Nurhayati Nurrobi, Mohamad Iqbal Prima Astuti Handayani Rahmi Ramadhani Rastramadhani, Faresa Aulia Rindradi, Ridha Saniyyah Riskawati, Yhusi Karina Safnita, Dewi Suchitra, Avit Syamel Muhammad Tofrizal Wildanur, Sri Yenita . Yona, Fajriza Zhuhra, Rahma Tsania