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All Journal HAYATI Journal of Biosciences Padjadjaran Journal of Dentistry Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Jamu Indonesia Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Muhammadiyah Journal of Geriatric Cermin Dunia Kedokteran Indonesian Journal of Jamu
Nafrialdi Nafrialdi
Department Of Pharmacology And Therapeutics, University Of Indonesia Medical School/ Dr. Cipto Mangunkusumo Hospital, Jakarta.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Other

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Differential Effects of Albumin Infusion between ICU and Non-ICU Hypoalbuminemia Patients Mariana, Nina; Wijaya, Surya Oto; Setyawati, Rumaisah; Maemun, Siti; Nafrialdi, Nafrialdi
Pharmaceutical Journal of Indonesia Vol. 7 No. 1 (2021)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2021.007.01.3

Abstract

Background: Hypoalbuminemia is frequent among hospitalized patients and is associated with poor outcomes. ICU patients are widely associated with more severe condition making albumin correction seems to be less effective. This study was aimed to compare the results of albumin correction in ICU and non-ICU patients at Sulianti Saroso Hospital, Jakarta. Methods: A cross sectional study was conducted on adult patients in ICU and non-ICU wards who received intravenous albumin infusion at Sulianti Saroso hospital, between January 2013 to March 2018. Paired t-test was used to analyze the changes of albumin level before and after albumin infusion. Results: 123 ICU patients (41 sepsis, 82 non-sepsis) and 206 non-ICU patients (34 sepsis, 172 non-sepsis) who received 20% or 25% albumin infusions were included. Significant increase in albumin levels were observed in sepsis patients both in ICU and non-ICU, while in non-sepsis patients, the significant increase only observed in non-sepsis patients. Overall, mean increase in albumin levels in ICU-and non-ICU patients were 0.13 (0.63) g/dL vs 0.35(0.54) g/dL, respectively (P= < 0,001). Conclusion: Non-ICU patients show better response to albumin infusion compared to ICU patients. This difference is presumably due to different degree of inflammation. It is suggested that the quantity needed for albumin infusion is calculated differently according to clinical condition of the patients   
Co-Authors -, Paramita Agatha Grace Ali Sulaiman Arini Setiawati Dewi Sharon Simorangkir Dewi, Yulia Ratna Ening Krisnuhoni Erni Erfan, Erni Eziefule, Oluebube Magnificient F. D. Suyatna Felix F. Widjaja Femmi Dwinda Agustini Frans D. Suyatna Gayatri, Anggi Handini, Novita M. Helyanna Helyanna, Helyanna Imam Effendi Indah D Dewijanti Indah D Dewijanti, Indah D Instiaty, Instiaty Irsan Hasan Isnani A.S. Suryono Joedo Prihartono Kenichi Watanabe Laurentius A Lesmana, Laurentius A Lukman H. Makmun M. Zaim Madoka Takeuchi Maemun, Siti Masahiro Takeuchi Meilei Ma Melva Louisa Mulyadi Djer Nabillah, Deya Adiby Nina Mariana, Nina Paramita, Paramita Pradana Soewondo Punniyakoti T. Veeraveedu Purwantyastuti Purwantyastuti Purwita Wijaya Laksmi Puspita Eka Wuyung Puspita Ekawuyung, Puspita Pustika Amalia Wahidiyat Rachman, Andika Raymond R. Tjandrawinata Rianto Setiabudy Rino Alvani Gani Sake Juli Martina Saut Horas Hatoguan Nababan SEPTELIA INAWATI WANANDI Seruni Tyas Khairunissa Setiabudy, Rahajuningsih D Setyawati, Rumaisah Siti Setiati Soni Siswanto Syarifah Dewi Theresia G Kurniawan, Theresia G Tirza Z Tamin Tri Yuliani Tri Yuliani, Tri Vetnizah Juniantito Vivian Soetikno Vivian Soetikno Vivian Soetikno Wasilah Rochmah Wawaimuli Arozal Wawaimuli Arozal Wawaimuli Arozal Wijaya, Ika P. Wijaya, Surya Oto