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Description of Hanifin-Rajka Criteria and Skin Hydration in Adult Patients with Mild-Moderate Atopic Dermatitis at Tertiary Hospital Umborowati, Menul Ayu; Jastika, Faradistiani Rakhmawati; Hendaria, Made Putri; Anggraeni, Sylvia; Damayanti; Sari, Maylita; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.20-25

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder that typically manifests in childhood and has a diverse etiology. In the United States, the prevalence of AD among adults was 4.9%, while in Japan it was 2.1%. The majority of people with AD have dry skin. Hanifin-Rajka criteria were the first to be established and are frequently used as diagnostic standards in research. Purpose: The purpose of this study is to determine the Hanifin-Rajka criteria and skin hydration in adult patients with mild-moderate atopic dermatitis at Dr. Soetomo General Academic Hospital, Surabaya March-May 2022.  Methods: This cross-sectional descriptive study included adult patients with mild to moderate AD according to Hanifin-Rajka aged 18-64 years who visited the Dermatology and Venereology Outpatient Dr. Soetomo General Academic Hospital Surabaya between March and May 2022. Skin hydration was measured using a corneometer on the volar side of the left forearm in the skin area.  Result: Based on the major criteria, all participants had pruritus, typical morphology and distribution, and chronic or chronically recurrent dermatitis. As for the minor criteria, more varied results were obtained, one of which was xerosis, which was experienced by all participants. The skin hydration shows that the mean value for skin hydration was 39.8 ± 12.1. The lowest skin hydration was 21.4 and the highest was 87.4, both found in subjects with mild AD. Conclusion: ..
Education and Workshop Improve Healthcare Workers' Knowledge of Laboratory Examination for the Diagnosis of Superficial Dermatomycosis Ervianti, Evy; Astari, Linda; Rahmadewi; Setyaningrum, Trisniartami; Mappamasing, Hasnikmah; Anggraeni, Sylvia; Widia, Yuri; Ngesti Kumalasari, Diah; Axelia, Presstisa Gifta; Hadiwidjaja, Farsha Naufal; Sunarto, Olivia Awwalin; Kathrin Kezia Henry; Sulaksanaswastho Suyoso; Puspowati, Erindah
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.187-192

Abstract

Background: Superficial dermatomycosis is one of the most prevalent skin diseases worldwide. The diagnosis of  superficial dermatomycosis is established clinically, and supported by several examinations, such as microscopic examination, fungal culture, and Wood's lamp examination for certain species. Purpose: This study is to evaluate the improvement of the knowledge of general practitioners and medical analysts after education and workshop. Methods: This cross-sectional observational study involved 70 subjects, consisting of 35 general practitioners and 35 medical analysts from 35 public health centers in Bojonegoro who were willing to participate in this study. The level of knowledge was assessed before and after the health education on laboratory examination for the diagnosis of superficial dermatomycosis. Result: There was a significant difference in mean scores between the pre-test and post-test after health education (p = <0.001). The mean knowledge score of the pre-test before intervention among general practitioners was 36.57 ± 19.088, which increased to 68.00 ± 13.240, and the mean knowledge score before intervention among analysts was 27.14 ± 13.842, which increased to 62.00 ± 12.078 after health education intervention. Conclusion: Following health education, there was an improvement in the healthcare workers's knowledge of laboratory examinations for the diagnosis of superficial dermatomycosis
Assessing the Potential Diagnostic Value of Indonesian Local Allergen Skin Prick Testing (SPT) for Cow’s Milk Allergy among Atopic Dermatitis Patients Anggraeni, Sylvia; Damayanti; Umborowati, Menul Ayu; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.88-93

Abstract

Background: Atopic dermatitis (AD) is a multifactorial chronic, frequently recurrent, inflammatory skin condition. The development of IgE-mediated food allergies and food sensitivity are both associated with atopic dermatitis. Cow’s milk allergy (CMA) caused the most common hypersensitivity reaction during childhood; however,  the prevalence in adults is around 0.5%. Patients with AD use the Skin Prick Test (SPT) to evaluate the specific sensitization process. Purpose: This study aimed to assess cow's milk allergy among adult AD patients using local allergen extract SPT, standard SPT, and specific IgE (sIgE), as well as evaluating the conformity and relevance of the test results. Methods: Using consecutive sampling technique, the study was conducted twice on 45 adult AD patients with a one-week interval between administrations. Result: Local cow's milk SPT showed 4 positive results, and standard SPT showed 5. No sIgE test was positive. Local SPT was negative for 86.67% of individuals without a history of suspected cow's milk allergies. Standard SPT results were positive for 2.22% of individuals with a history of suspected cow's milk allergies and negative for 86.67% of those without. The relevance between local and standard SPT was shown to be substantial (k = 0.384, p = 0.000). Conclusion: The result of the local cow’s milk SPT and the patient’s history had good conformity, and the relevance with standard SPT was significant in diagnosing cow’s milk allergy among AD patients.
Philosophy's Contribution to Cultural Transformation in The Era of Technological Revolution Anggraeni, Sylvia; Sadiyah, Nurhalimatus; Mahardika, I Ketut; Suratno, Suratno
International Journal of Education, Information Technology, and Others Vol 7 No 4 (2024): International Journal of Education, information technology   and others (IJEIT)
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The Fourth Industrial Revolution, with disruptive technologies such as artificial intelligence, IoT, and big data, brings significant changes to the way we live, work, and our cultural values. Philosophy plays a crucial role in preserving fundamental values, ensuring that culture remains adaptable without losing its essence amidst these transformations. Through a critical approach, philosophy aids in designing an inclusive and humanistic future, addressing ethical, epistemological, and ontological challenges. In ethics, philosophy tackles issues like privacy, algorithmic bias, and social inequality through deontological and utilitarian approaches. In epistemology, it promotes digital literacy to distinguish between true and false information, while in ontology, it explores the impact of technology on identity and reality. Furthermore, philosophy contributes to cultural transformation by promoting sustainability and preserving local heritage, guiding technology and culture toward a more just and sustainable future.
Clinical Relevance of House Dust Mites as Causative Factor of Atopic Dermatitis in Surabaya-Indonesia Sylvia Anggraeni; Bella Ayu Paramitha; Wisnu Triadi Nugroho; Menul Ayu Umborowati; Damayanti Damayanti; Anang Endaryanto; Cita Rosita Sigit Prakoeswa
Proceedings International Conference on Sustainable Innovation (ICoSI) Vol. 1 No. 1 (2021): Maximizing Opportunities and Research for a Better Life
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/icosi.v3i1.33

Abstract

Atopic dermatitis (AD) is chronic inflammation of skin manifested as recurrent itchy redness patches. Avoiding precipitating factors is significant key of successful treatment, but not always possible. House dust mites (HDM) are the most common but not easily proven as aeroallergen. Skin prick test (SPT) is an effective diagnostic modality in recognizing type 1 hypersensitivity reaction. Positive result on SPT should be confirmed by clinical relevance to find the true causative factor. The aim of the study was to analyze the clinical relevance of HDM as AD causative factor in Surabaya, Indonesia. This is a descriptive observational study. Sixty samples were taken from SPT medical records in Allergy-Immunology Division outpatient care at Dr. Soetomo General Academic Hospital period of 2017 - 2019. All samples that qualify inclusion criteria were included. Data were compiled in data sheet, categorized as nominal, and presented as clinical relevance. This study reported that AD is more common in 21-30 years old (70%), Javanese (93.33%), female (783.3%). Most of them had history of itchy redness patches (83.33%), dry skin (55%), self and family history of atopic disease (93.33%; 53.33%). History of suspected HDM allergen was 50%, positive SPT results were 68,33%. Clinical relevance had shown that in 37 patients (61,67%), 17 out of 23 (73.92%) patients did not suspect HDM as allergen but has positive SPT results. It may conclude that HDM should be considered as hidden potent causative factor of AD in Surabaya, Indonesia.
Profile of Transepidermal Water Loss in Non-Atopic Dermatitis and Atopic Dermatitis in Indonesian Adults Damayanti; Anggraeni, Sylvia; Ayu Umborowati, Menul; Farah Adiba, Asmahan; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.28-33

Abstract

Background: Atopic dermatitis (AD) is a recurrent and chronic inflammatory skin disease affecting the quality of life and productivity of individuals. Several studies have reported the profile of transepidermal water loss (TEWL) in AD patients, however, there is either no data or very limited data on TEWL values in normal skin or in non-atopic individuals. Purpose: This study aims to update of the available evidence about TEWL values in healthy (non-AD) adults and AD patients, especially in Indonesia. Methods: This analytic study involved 37 non-AD subjects and 37 subjects with AD. TEWL measurements were assessed on the volar side of the left forearm. Result: The mean values in the non-AD group were 5.61 ± 3.85, while the mean values in the AD group were 18.07 ± 4.88. There is a significant difference in TEWL ​​values between the groups with non-atopic dermatitis and atopic dermatitis (p<0.001). Conclusion: TEWL value is significantly higher in AD patients compared to non-AD  individuals, indicating a compromised skin barrier function in AD. The consistent results across populations and geographic regions support the utility of TEWS as a reliable measure of AD severity, which can help clinicians customize treatment plans to meet the needs of each patient.
Profile of Patients with Viral Infection at the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2016-2018 Putri, Melati Adinda; Astari, Linda; Bramantono, Bramantono; Anggraeni, Sylvia
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.122-128

Abstract

Highlights: The most common viral skin infections at the Dermatology and Venerology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2016-2018 were shingles, verruca vulgaris, varicella, molluscum contagiosum, and measles. Viral skin infections predominantly affected late teens (17-25 years old), females, and each disease presented different clinical manifestations and treatments.   Abstract Introduction: The high incidence of viral skin infections in Indonesia, combined with a lack of understanding of risk factors and prevention measures, poses a significant problem. Few studies have examined the epidemiological profile of viral skin infections in Indonesia. This study aimed to evaluate the profile of patients with viral infections at the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2016 to 2018. Methods: This was a descriptive, retrospective study based on the medical records of 560 patients collected between January 2016 and December 2018 (n=560). All data calculations were performed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26. Results: The prevalence of the five viral infections was 71.8% among all patients with viral infections. The most common diagnosis was shingles (47.5%), the most affected age group was late teens (17-25 years old) (21.3%), the most common gender was female (52,9%), the most frequent clinical manifestation was vesicles (52.1%), and the most commonly used therapy type was topical (73.4%). Conclusion: The number of patients with viral infections at the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, has increased annually, requiring more comprehensive management to reduce morbidity and mortality.