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<![CDATA[PENGARUH PENERAPAN MODIFIKASI PERMAINAN BOLA VOLI TERHADAP HASIL BELAJAR PASING BAWAH DAN PASING DI SDI ILIGETANG ]]>
<![CDATA[Timba, Frederiksen Novenrius Sini]]>;
<![CDATA[Ritan, Paskalis Suban]]>
<![CDATA[ Metodik Didaktik : Jurnal Pendidikan Ke-SD-an Vol 16, No 2 (2021): Metodik Didaktik Januari 2021 ]]>
Publisher : <![CDATA[Universitas Pendidikan Indonesia ]]>
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DOI: 10.17509/md.v16i2.27943
<![CDATA[This study purposes to analyze the effect of skills on and through volleyball analysis techniques on student learning outcomes of class IVA SDI Iligetang, Beru, Alok Timur District. The research subjects of class VI A SDI Iligetang. The method used in pre-design research was one group pre-test post-test design. The results obtained were that the positive effect of the application of modification in volleyball to improve student learning outcomes was seen from changes in the pre-test and post-test scores where there was an increase from five students who passed the pre-test to twenty three students at the post-test stage. Modification of the volleyball game also positively affects the over and under passing skills of grade IV SDI Iligetang students, Beru, Alok Timur District, Sikka Regency, 2019/2020 Academic Year. The conclusion is that the volleyball game's modification is feasible to be used as alternative learning in improving student learning outcomes.]]>
<![CDATA[PENGARUH LATIHAN LONCAT KATAK DAN LONCAT NAIK TURUN BANGKU TERHADAP KEMAMPUAN LOMPAT JAUH GAYA JONGKOK SISWA PUTRA KELAS V SEKOLAH DASAR KATOLIK 077 KEWAPANTE ]]>
<![CDATA[Frederiksen Novenrius Sini Timba]]>;
<![CDATA[Yanuarius Yanuarius]]>
<![CDATA[ Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 5 No. 2 (2020): Volume 5 Nomor 2 Desember 2020 ]]>
Publisher : <![CDATA[Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan ]]>
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DOI: 10.23969/jp.v5i2.3563
<![CDATA[The purpose of this study was to identify the effect of frog jumping and bench jumping up and down on the squat style long jump ability of male students of grade V SDK 077 Kewapante. The research method that is adapted is a pre-experimental research with the research design used is the One-Shot Case Study. The sample used in this study amounted to 10 people. The data collection techniques in this study used tests, observation, and documentation. The data analysis technique used is to use statistical paired samples analysis with the help of the SPSS program. Data analysis shows evidence of t value (1,000) <t table (18.30). The results show that learning PJOK with the application of jumping frogs and jumping up and down benches has an effect on the ability of male students' squat style long jump in grade V SDK 077 Kewapante.]]>
<![CDATA[DESKRIPSI PELAKSANAAN PEMBELAJARAN SECARA DARING PADA MASA PANDEMI COVID-19 DI SD KHATOLIK MARIA FERRARI ]]>
<![CDATA[Maria Herliyani Dua Bunga]]>;
<![CDATA[Bergita Nona Timur]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>
<![CDATA[ Tunas Nusantara Vol 3, No 2 (2021) ]]>
Publisher : <![CDATA[Universitas Islam Nahdlatul Ulama Jepara ]]>
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DOI: 10.34001/jtn.v3i2.2652
<![CDATA[The study aims to implement bold thematic learning (online) during the CoronaVirus Diseases 2019(Covid -19) pandemic at the Maria Ferrari SDK. This study used qualitative research methods. The results show that thematic learning boldly uses applications: Microsoft Office Word, Microsoft Office PowerPoint, WhatsApp, Google Forms, Format Factory, Fast Tone Capture, VideoScribe, and Youtube. The teacher provides learning materials and videos for students to study at home so that students carry out learning boldly through learning applications. The teacher also provides quiz questions, tests, and exams so that students can work on these questions boldly. Based on the results of the study, it can be seen that the thematic learning implementation process is boldly carried out by utilizing applications to design teaching materials and learning videos for students as well as presenting questions so that the bold learning process can run effectively and efficiently.]]>
<![CDATA[Pengaruh Penggunaan Media Animasi Terhadap Kemampuan Membaca Permulaan Siswa Selama Pandemi Covid-19 ]]>
<![CDATA[Maria Helvina]]>;
<![CDATA[Agnes Yosefina Noeng]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>
<![CDATA[ Tunas Nusantara Vol 3, No 2 (2021) ]]>
Publisher : <![CDATA[Universitas Islam Nahdlatul Ulama Jepara ]]>
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DOI: 10.34001/jtn.v3i2.2700
<![CDATA[Beginning reading ability is a person's basic ability to master various fields of knowledge so it is very important to master. The ability to read at the beginning of grade 1 SDI Patisomba is still very low because students do not know letters well. This study aims to determine the effect of using animated media on initial reading skills in grade 1, students at SDI Patisomba during the covid-19 pandemic. This study used quantitative research methods with data collection techniques including tests and observations, analyzed using the t-test. From the results of the t-test calculation, there is a t count of 2.410 and a t-table with dk = 15 and the significant level = 0.05 is 1.753. It can be concluded that t count > t table (2,410>1,753) so that Ho is rejected and Ha is accepted, that is, there is an effect of using animation media on early reading skills in grade 1 students of SDI Patisomba. Based on the test results and observation results and analyzed using the T-test, it can be concluded that the students' initial reading ability and the learning outcomes of class 1 students have changed for the better after using animation media in the experimental class.]]>
<![CDATA[MENINGKATKAN KETERAMPILAN SERVIS DAN PASSING BOLA VOLI MELALUI PERMAINAN VOLSAL PADA SISWA KELAS III SD KATOLIK 143 BHAKTYARSATAHUN PELAJARAN 2017/2018 ]]>
<![CDATA[Frederiksen Novenrius S. Timba]]>
<![CDATA[ Jurnal Akrab Juara Vol 4 No 1 (2019) ]]>
Publisher : <![CDATA[Yayasan Akrab Pekanbaru ]]>
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<![CDATA[The researcher has got the data of research result from each cycle which shows the improvement of the students skill. On the observation of the teacher activity in first cycle of Meeting one reached an average of 76.31 and Meeting two reached an average of 81.57as a good categories. In the second Cycle of Meeting one reached an average of 89.47 and Meeting two to 96.05 with very good category. In the first cycle of student activity in Meeting one reached 80 average with a good category, and Meeting two reached 85 category averageas a very well category. While in the second cycle of Meeting one reached an average of 90 as very well categories and Meeting two increased again to 95 with very good category. On the observation result of student attitude in learning process at first cycle of meeting one reaching average 84,28 with good category, in meeting 2 reaching average 88,57 with very good category, while at second cycle of meeting one reach flat 92, 85 with very good category, and meeting 2 reaches average 95,71 with very good category. On the skills of students who experienced an increase in the first cycle of meeting one the average score reached 79.46 students and meeting 2 students average score reached 83.92 and 100% classical completeness with good category. The average value obtained in second cycle of meeting one is 92.41 and the meeting two is 97.32 and the classical completeness is 100% in very good category. Thus it can be concluded that the use of volsal game can improve the students' skills of the service materials and volleyball that passes on the third grade students of Catholic Elementary School 143 Bhaktyarsa of Sikka Regency in the Academic Year of 2017/2018.]]>
<![CDATA[Eksplorasi Senyawa Kulit Kopi sebagai Anti Covid-19 Melalui Penghambatan 3C-Like Protease ]]>
<![CDATA[Yohanes Bare]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>;
<![CDATA[Maria Marcelina Dua Nurak]]>;
<![CDATA[Marsiana Coo Mogi]]>
<![CDATA[ JURNAL PENDIDIKAN MIPA Vol 12 No 2 (2022): JURNAL PENDIDIKAN MIPA ]]>
Publisher : <![CDATA[Pusat Publikasi Ilmiah, STKIP Taman Siswa Bima ]]>
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DOI: 10.37630/jpm.v12i2.563
<![CDATA[Corona virus 19 menjadi pandemic di dunia saat ini, oleh karena itu perlu dilakukan terapi sehingga menurunkan prevalensi di Indonesia dengan menghambat protein yang terlibat dalam virus corona (3CL Protease). Salah satunya pemanfaatan bahan alam yang tidak terpakai. Kulit kopi merupakan material sisa dari pengolahan biji kopi. Satu ton ampas kopi akan terbentuk dari 2 ton kopi yang diproduksi dan berdampak terhadap masalah lingkungan. Kulit kopi memiliki berbagai macam senyawa yang masih dibutuhkan. Produksi kopi Tujuan penelitian ini adalah pemanfaatan bahan aktif kulit kopi sebagai nutrisi tingkat gen dengan menghambat kinerja 3C-like protease (3CLPro). Metode penelitian in silico, senyawa kulit kopi Hexosa (ID. 206), Malic acid (ID. 525), D-manitol (ID. 88038555) diunduh dari PubChem, protein 3CL Protease diunduh dari database protein data bank (PDB) dengan ID 2zu2 diimport ke software Molegro virtual docker 5 dan dilakukan preparasi. Selanjutnya protein target diprediksi cavity (sisi aktif protein) dengan parameter expand van der Waals maximum 10. Hasil docking dilakukan superimposed dengan protein yang telah dipreparasi menggunakan software PyMol. Visualisasi hasil docking dilakukan menggunakan perangkat lunak HEX 8.0.0.0. Hasil penelitian senyawa yang terkandung dalam kulit kopi memiliki potensi sebagai anti covid-19, hal ini dibuktikan dengan aktivitas senyawa Hexosa, Malic acid, D-manitol yang mengikat masing-masing enam residu asam amino. Pengikatan terhadap delapan belas residu asam amino yang berbeda diprediksi menjadi alternatif nutrisi dengan menghambat 3CL Protease.]]>
<![CDATA[KAJIAN SENYAWA HEXOSE DAN MALIC ACID SEBAGAI INHIBITOR PAPAIN LIKE PROTEASE (PLPro) CORONA VIRUS ]]>
<![CDATA[Yohanes Bare]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>;
<![CDATA[Sukarman Hadi Jaya Putra]]>;
<![CDATA[M A Yohanita Nirmalasari]]>;
<![CDATA[Dewi Ratih Tirto Sari]]>;
<![CDATA[Maximus M Taek]]>
<![CDATA[ JURNAL BIOSENSE Vol 5 No 01 (2022): Edisi Juni 2022 ]]>
Publisher : <![CDATA[Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas PGRI Banyuwangi, Jalan Ikan Tongkol No 01, Telp (0333) 421593, 428592 Banyuwangi 68416 ]]>
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DOI: 10.36526/biosense.v5i01.1997
<![CDATA[Papain-like protease is a SARSCOV-2 protease that functions for ubiquitination in host cells. Caffeine compounds have been widely reported to have antioxidant, anti-inflammatory, antidiabetic, and antiobesity activities. However, hexose and malic acid compounds in coffee rind as potential inhibitors of the papain-like protease SARSCOV2 have not been reported. This study investigated the potential of malic acid and hexose compounds as PLPro inhibitor agents in inhibiting SARSCOV2 ubiquitination. In silico studies were used to identify the potential of the two compounds by interacting hexose and malic acid compounds with papain-like protease (PLPro) proteins with the Molegro virtual Docker 5 program. Next, the ligand-protein complex visualization was done with discovery studio version 5.0. hexose and malic acid compounds showed interactions with papain-like protease proteins on several active site residues. The interactions showed inhibition of ubiquitination and stimulation of interferon in host cells. The two compound complexes – PLPro protein showed hydrophobic interactions, hydrogen bonds, and van der Waals forces, which contributed to the formation of bond energy and strong bonds between compounds and proteins. In this study, it was concluded that hexose and malic acid compounds have the potential to act as inhibitors of papain-like protease (PLPro) protein.]]>
<![CDATA[Interaksi Molekuler Senyawa D-Manitol (Kulit Kopi) terhadap PLPro ]]>
<![CDATA[Yohanes Bare]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>;
<![CDATA[Maria Marcelina Dua Nurak]]>;
<![CDATA[Dewi Ratih Tirto Sari]]>;
<![CDATA[Marsiana Coo Mogi]]>
<![CDATA[ SPIZAETUS: JURNAL BIOLOGI DAN PENDIDIKAN BIOLOGI Vol 3, No 3 (2022): Spizaetus: Jurnal Biologi dan Pendidikan Biologi ]]>
Publisher : <![CDATA[Universitas Nusa Nipa ]]>
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DOI: 10.55241/spibio.v3i3.79
<![CDATA[Perkembangan virus dalam proses replikasi menjadi target dalam menghambat siklus hidup virus. Protein yang memiliki peran dalam replikasi adalah PLPro. Terapi PLPro dilakukan dengan memanfaatkan limbah kopi yang diprediski memilki bioaktif D-manitol dengan sifat farmakologis. Tujuan penelitian ini adalah mengalisis potensi senyawa D-manitol yang terkandung dalam kulit kopisebagai kandidat terapi corona melalui penghambatan PLPro. Metode penelitian Ligan D-manitol (CID: 88038555) sedangkan Protein Papain like protease (PLPro) (PDB ID 6w9c), sebagai target protein anti-coronavirus diunduh struktur tiga dimensinya di Protein Data Bank. Selanjutnya struktur protein dipreparasi protein atau ligan, docking, visualisasi mengikuiti penelitian. Hasil docking senyawa dan protein menggunakan program PyMol versi 2.2. analisis docking dilakukan dengan mengeksplorasi interaksi kompleks baik 3D dan 2d, jenis ikatan, jumlah interaksi. Analisis menggunakkan program Discovery Studio ver 21.1.1.). Senyawa D-manitol memiliki potensi sebagai salah satu terapi covid-19 melalui penghambatan PLPro sehingga menyebabkan terhambatnya replikasi virus corona. Potensi ini didukung dengan adanya energi ikatan yang terbentuk sehingga meningkatkan stabilitas ikatan sebesar -156 Kj/mol. Penelitian lanjutan perlu dilakukan untuk konfirmasi terhadap aktivitas D-manitol sebagai terapi virus.]]>
<![CDATA[Kajian in silico Penghambatan Spesifik 3C-like Protease SARS-CoV-2 Senyawa Quinic Acid, Gluconic Acid, dan Ferulic Acid pada Kulit Kopi ]]>
<![CDATA[Yohanes Bare]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>;
<![CDATA[Dewi Ratih Tirto Sari]]>;
<![CDATA[Oktavius Yoseph Tuta Mago]]>;
<![CDATA[Maria Marcelina Dua Nurak]]>
<![CDATA[ Jurnal Ilmiah Medicamento Vol 8 No 2 (2022): Jurnal Ilmiah Medicamento ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Mahasaraswati Denpasar ]]>
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DOI: 10.36733/medicamento.v8i2.3971
<![CDATA[This study aims to explore the chemical compounds of the coffee pulp as an anti-covid-19 (anti-3C-like protease). In silico modeling was carried out by structure retrieval, protein preparation, and docking simulation. Specific Grid docking was used for ligands – protein interacting by using Molegro Virtual Docker 5, followed by visualizing Discovery studio version 21.1.1. Compounds contained in coffee pulp, quinic acid, gluconic acid, and ferulic acid separately bind to the same amino acid residues of 3CL Protease or each other. Furthermore, three compounds inhibited 3CLPro activity by catalytic site blocking of 3CLPro, indicating that coffee compounds have potential as molecular therapeutic materials for the coronavirus by inhibiting SARS-CoV-2 genome replication.]]>
<![CDATA[PENGARUH PENGGUNAAN E-LEARNING TERHADAP HASIL BELAJAR PESERTA DIDIK PADA MATA PELAJARAN IPA KELAS VI SEKOLAH DASAR ]]>
<![CDATA[Maria Florida Tokan]]>;
<![CDATA[Frederiksen Novenrius Sini Timba]]>;
<![CDATA[Desi Maria El Puang]]>
<![CDATA[ Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 7 No. 2 (2022): Volume 07, Nomor 02, Desember 2022 ]]>
Publisher : <![CDATA[Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan ]]>
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DOI: 10.23969/jp.v7i2.6569
<![CDATA[Penggunaan media pembelajaran mempunyai manfaat yang cukup besar dalam pembelajaran terkhusus pada siswa sekolah dasar. Berdasarkan hasil pengamatan awal pada peserta didik kelas VI SD Inpres Nogodue, masalah yang ditemukan adalah ketika guru mengajar, guru tidak menggunakan media pembelajaran tetapi hanya fokus pada bahan ajar berupa buku tanpa menggunakan media pembelajaran. Guru hanya menggunakan media gambar yang terdapat dalam buku untuk dijelaskan kepada peserta didik. Guru lebih banyak menjelaskan materi dan kurang memberikan contoh sehingga menyebabkan peserta didik menjadi bosan dan kurang paham dengan materi yang diajarkan. Hal ini juga berdampak terhadap menurunnya hasil belajar peserta didik. Adapun solusi yang diambil untuk mengatasi masalah ini adalah dengan menggunakan e-learning dalam pembelajaran. Penelitian ini bertujuan untuk menjelaskan pengaruh penggunaan e-learning terhadap hasil belajar peserta didik pada mata pelajaran IPA kelas VI sekolah dasar. Jenis penelitian yang digunakan yakni kuantitatif dengan model eksperimen. Desain penelitian ini menggunakan one group pretest posttest design dengan sampel berjumlah 13 peserta didik. Teknik penelitian yang digunakan adalah tes dan observasi dengan Instrumen berupa soal tes dan lembar observasi. Hasil penelitian menunjukkan bahwa nilai rata-rata peserta didik pada pretest 72,92, sementara itu nilai rata-rata posttest ialah 86,19 dengan hasil pengujian hipotesis diperoleh nilai signifikasi (2-tailled) sebesar 0,000 ≤ 0,005 maka Ha diterima dan Ho ditolak. Dengan demikian, hasil ini menunjukkan terdapat pengaruh penggunaan e-learning terhadap hasil belajar peserta didik pada mata pelajaran IPA kelas VI SD Inpres Nogodue.]]>
