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All Journal BERDIKARI : Jurnal Inovasi dan Penerapan Ipteks Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JURNAL IBNU SINA BIOMEDIKA Buletin Farmatera Hasil Pengabdian Kepada Masyarakat Majalah Kedokteran Andalas Jurnal Aisyah : Jurnal Ilmu Kesehatan JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Jurnal Implementa Husada Jurnal Pandu Husada JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Jurnal Pengabdian Ilmu Kesehatan
Nuralita, Nanda Sari
UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA
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Hubungan Efek Metabolik dan Hormon Kortisol Terhadap Pasien Gangguan Ansietas yang Berobat di Poli Psikiatri RS Madani Medan Nuralita, Nanda Sari
Majalah Kedokteran Andalas Vol. 46 No. 4 (2023): Online Oktober
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i6.p886-893.2023

Abstract

Pendahuluan: Gangguan ansietas merupakan suatu kondisi yang sering dijumpai pada masyarakat secara umum. Gangguan ansietas jangka panjang dapat menyebabkan peningkatan hormon adrenalin sehingga terjadi peningkatan asam lemak bebas dan kadar glukosa darah, dan juga menyebabkan pelepasan hormon kortisol, yaitu hormon glukokortikoid yang disintesis dari kolesterol di korteks adrenal, yang dapat memberikan dampak negative terhadap efek kardiovaskular, metabolisme dan pernapasan. Kortisol umumnya dikenal sebagai "hormon stres", yang hanya dilepaskan selama kondisi stres. Tujuan: tujuan penelitian ini unutuk melihat hubungan antara efek metabolik terhadap peningkatan hormon kortisol pada pasien yang mengalami gangguan ansietas. Metode: penelitian merupakan penelitian analitik numerik dengan cara cross sectional, cara pengambilan sampel dengan cara non probability sampling jenis consecutive sampling, dengan jumlah sampel sebanyak 25 orang. Hasil: Terdapat perbedaan bermakna antara gangguan ansietas terhadap peningkatan kadar gula darah (p=0.001, r =0,625) dan kadar kolesterol (p<0.001, r=0,717). Tidak Terdapat perbedaan yang bermakana antara gangguan ansietas terhadap peningkatan hormone kortiso dengan nilai P=0.366, r=0,189. Kesimpulan: Dijumpai perbedaan bermakna antara gangguan ansietas terhadap peningkatan kadar gula darah dan kolesterol, tidak dijumpai perbedaan yang bermakana antara gangguan ansietas terhadap peningkatan hormon kortisol.
Hubungan Simtom Depresi dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUD Drs. H. Amri Tambunan: Hubungan Simtom Depresi dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUD Drs. H. Amri Tambunan Pohan, Muhammad Alwi; Tambunan, Asri Ludin; Nuralita, Nanda Sari; Chaniago, Lita Septina
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 10 No 3 (2024): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 10.3 2024
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v10i3.792

Abstract

Background: Chronic kidney disease is a disease that occurs as a result of structural and functional kidney damage that lasts for more than three months with a glomerular filtration rate (GFR) or Glomerular Filtration Rate (GFR) of less than 60mL/min/1.73 m2. The prevalence of kidney failure in Indonesia increases every year, to treat it requires kidney replacement therapy, one of which is hemodialysis which must be done for life. Hemodialysis therapy is a substitute for kidney function to remove metabolic waste or certain toxins from human blood circulation which aims to remove fluids, electrolytes and metabolic waste from the body, thereby indirectly extending the patient's life. Objective: To determine the relationship between depression and the quality of life of chronic kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan. Population: The population in this study were patients with chronic kidney disease undergoing hemodialysis at the hemodialysis unit of RSUD Drs. H. Amri Tambunan. The number of research samples is 40 people. Method: The type of research used is categorical correlative analytic in RSUD Drs. H. Amri Tambunan. This study used a cross-sectional design. The research instrument used the KDQOL-SF and BDI which were analyzed using the Spearman test. Results: Kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan did not experience depression as many as 22 respondents (55.0%) while the quality of life was mostly in the category of moderate quality of life as many as 22 people (55.0%). Conclusion: After the spearment statistical test was carried out, a significant value or sig (2-tailed) of 0.001 was obtained which showed that there was a relationship between depressive symptoms and the quality of life of chronic kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan. The correlation coefficient value was 0.524 which indicated that there was a strong relationship between depressive symptoms and the quality of life of chronic kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan. The correlation coefficient is negative, namely -0.524, so the relationship between the two variables is not unidirectional.Thus it can be interpreted that the higher the symptoms of depression, the level of quality of life will decrease.
The Relationship between Metabolic Effects and the Hormone Cortisol on Anxiety Disorder Patients Treating at Madani Hospital Medan Nuralita, Nanda Sari
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 9, No 1 (2024): March 2024
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v9i1.2608

Abstract

Introduction: Anxiety disorder is a condition that is often found in society in general. Long-term anxiety disorders can cause an increase in the hormone adrenaline resulting in an increase in free fatty acids and blood glucose levels, and also cause the release of the hormone cortisol, which is a glucocorticoid hormone synthesized from cholesterol in the adrenal cortex, which can have a negative impact on cardiovascular, metabolic and respiratory effects. Cortisol is commonly known as the "stress hormone", which is only released during stressful conditions. Research method: This research is a numerical analytic study with a cross sectional method, the sampling method is non-probability sampling with consecutive sampling type, with a total sample of 25 people. Results: There was a significant difference between anxiety disorders and an increase in blood sugar(p=0.001, r =0,625) and cholesterol levels (p0.001, r=0,717). There was no significant difference between anxiety disorders and an increase in cortisone hormone with P= 0.366, r=0,189 .Conclusion: There was a significant difference between anxiety disorders and an increase in blood sugar and cholesterol levels, there was no significant difference between anxiety disorders and an increase in the hormone cortisol.
Perbandingan Penggunaan Antipsikotik Atipikal Tunggal Dan Antipsikotik Atipikal Kombinasi Terhadap Kadar Ldl Pada Pasien Skizofrenia Toniara, Safriwan; thristy, Isra; Nuralita, Nanda Sari
Buletin Farmatera Vol 11, No 3 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i3.28213

Abstract

Abstract: Schizophrenia is a collection of psychotic disorders with irregularities in the thought process, which have the feeling that they are controlled by external forces, delusions, perceptual disorders and abnormal effects integrated with real situations or reality. The use of antipsychotics in schizophrenic patients is the treatment of this disease, especially the most commonly used atypical antipsychotic users. This study aims to compare LDL (low-density lipoprotein) levels in schizophrenia patients who use single atypical antipsychotics and combination atypical antipsychotics at Madani Hospital Medan, North Sumatra. This type of research is descriptive analytical using  a cross-sectional  method that takes data on variable-free bound variables at one time, which is housed at the Upt Health Laboratory. North Sumatra Provincial Health Office. The results of the Independent T-Test of the use of single antipsychotics and a combination of atypical antipsychotics on LDL levels in schizophrenia patients were p=0.001 (P≤0.05). There was a significant difference between the administration of a single atypical antipsychotic and a combination of atypical antipsychotics to LDL levels in patients with schizophrenia.
Hubungan Tingkatan Simtom Kecemasan dengan Self-Esteem Pelajar SMA Swasta Muhammadiyah 02 Medan Nathasya Putri Kinanti; Nanda Sari Nuralita; Nurhasanah Nurhasanah; Des Suryani
Jurnal Pengabdian Ilmu Kesehatan Vol. 5 No. 3 (2025): November: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v5i3.5891

Abstract

Anxiety is a condition when emotions that arise when individuals are under stress, and is characterized by feelings of tension, thoughts that make individuals feel worried and accompanied by physical responses (heart beat fast, increased blood pressure, and others).1 Anxiety is related to fear and manifests as a future-oriented state of mind consisting of a complex cognitive, affective, physiological, and behavioral response system associated with preparation for anticipated events or circumstances that are considered threatening. Excessive anxiety can interfere with daily activities and be a sign of general anxiety disorder. Self-esteem is one of the main factors of how individuals see themselves or the concept of self and becomes an important determinant in human behavior. Early adolescence is the most decisive period in the formation of self-esteem which is characterized by the emergence of positive or negative self-esteem changes. Method: This type of research is analytic descriptive research with a cross sectional design. This research was conducted by looking at the relationship between the level of anxiety symptoms and self-esteem in students by giving the Beck Anxiety Inventory (BAI) and Rosenberg Self-Esteem Scale (RSES) questionnaires as research measurement tools. In this study using a sample of 90 people, where the sample was divided according to strata as many as 30 samples. Test data in this study using univariate test and bivariate test Chi-Square test. Results: the test results found that there was a relationship between the level of anxiety symptoms on the self-esteem of students of SMA Swasta Muhammadiyah 02 Medan and obtained a significant value of <0.001 (p<0.05). Conclusion: there is a significant relationship between the level of anxiety disorders to self-esteem in students of SMA Swasta Muhammadiyah 02 Medan.
Co-Authors Adelia azis Azis Nasution Amelia Eka Damayanty Asri Ludin Tambunan Azzahra, Syifa Nadya BAITUL AMANAH BATUBARA, DIAN ERISYAWANTY CHANIAGO, LITA SEPTINA DAMAYANTI, AMELIA EKA DAPOT PARULIAN GULTOM Debby Mirani Lubis Debby Mirani Lubis Des Suryani Des Suryani ELMAN BOY ELMEIDA EFFENDY ELVIANI . ILHAM SYAHPUTRA Isra Thristy Isra Thristy LITA SEPTINA CHANIAGO Lubis, Debby Mirani Maharani, Vivia Melviana Lubis Muhammad Alwi Pohan Muhammad Iqbal Nathasya Putri Kinanti Nurhasanah Nurhasanah Nurhasanah Nurhasanah Octari Auliati Pohan, Muhammad Alwi Rizaldi, Aril RIZANA, RARA RIZKI WAHYU NAFIAH Robitah Asfur SAID MUNAZAR RAHMAT Siregar, Pinta Pudiyanti Siregar, Syahroni Siti Andira Sri Rizky Ayunita Tambunan, Asri Ludin Toniara, Safriwan TRIA ARDITA ZAHRAH SAFIRA Zulhilmi, Zulhilmi