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Hubungan Simtom Depresi dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUD Drs. H. Amri Tambunan: Hubungan Simtom Depresi dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUD Drs. H. Amri Tambunan Pohan, Muhammad Alwi; Tambunan, Asri Ludin; Nuralita, Nanda Sari; Chaniago, Lita Septina
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 10 No 3 (2024): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 10.3 2024
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v10i3.792

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Background: Chronic kidney disease is a disease that occurs as a result of structural and functional kidney damage that lasts for more than three months with a glomerular filtration rate (GFR) or Glomerular Filtration Rate (GFR) of less than 60mL/min/1.73 m2. The prevalence of kidney failure in Indonesia increases every year, to treat it requires kidney replacement therapy, one of which is hemodialysis which must be done for life. Hemodialysis therapy is a substitute for kidney function to remove metabolic waste or certain toxins from human blood circulation which aims to remove fluids, electrolytes and metabolic waste from the body, thereby indirectly extending the patient's life. Objective: To determine the relationship between depression and the quality of life of chronic kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan. Population: The population in this study were patients with chronic kidney disease undergoing hemodialysis at the hemodialysis unit of RSUD Drs. H. Amri Tambunan. The number of research samples is 40 people. Method: The type of research used is categorical correlative analytic in RSUD Drs. H. Amri Tambunan. This study used a cross-sectional design. The research instrument used the KDQOL-SF and BDI which were analyzed using the Spearman test. Results: Kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan did not experience depression as many as 22 respondents (55.0%) while the quality of life was mostly in the category of moderate quality of life as many as 22 people (55.0%). Conclusion: After the spearment statistical test was carried out, a significant value or sig (2-tailed) of 0.001 was obtained which showed that there was a relationship between depressive symptoms and the quality of life of chronic kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan. The correlation coefficient value was 0.524 which indicated that there was a strong relationship between depressive symptoms and the quality of life of chronic kidney disease patients undergoing hemodialysis at Drs. H. Amri Tambunan. The correlation coefficient is negative, namely -0.524, so the relationship between the two variables is not unidirectional.Thus it can be interpreted that the higher the symptoms of depression, the level of quality of life will decrease.
The Relationship between Metabolic Effects and the Hormone Cortisol on Anxiety Disorder Patients Treating at Madani Hospital Medan Nuralita, Nanda Sari
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 9, No 1 (2024): March 2024
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v9i1.2608

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Introduction: Anxiety disorder is a condition that is often found in society in general. Long-term anxiety disorders can cause an increase in the hormone adrenaline resulting in an increase in free fatty acids and blood glucose levels, and also cause the release of the hormone cortisol, which is a glucocorticoid hormone synthesized from cholesterol in the adrenal cortex, which can have a negative impact on cardiovascular, metabolic and respiratory effects. Cortisol is commonly known as the "stress hormone", which is only released during stressful conditions. Research method: This research is a numerical analytic study with a cross sectional method, the sampling method is non-probability sampling with consecutive sampling type, with a total sample of 25 people. Results: There was a significant difference between anxiety disorders and an increase in blood sugar(p=0.001, r =0,625) and cholesterol levels (p0.001, r=0,717). There was no significant difference between anxiety disorders and an increase in cortisone hormone with P= 0.366, r=0,189 .Conclusion: There was a significant difference between anxiety disorders and an increase in blood sugar and cholesterol levels, there was no significant difference between anxiety disorders and an increase in the hormone cortisol.
Perbandingan Penggunaan Antipsikotik Atipikal Tunggal Dan Antipsikotik Atipikal Kombinasi Terhadap Kadar Ldl Pada Pasien Skizofrenia Toniara, Safriwan; thristy, Isra; Nuralita, Nanda Sari
Buletin Farmatera Vol 11, No 3 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i3.28213

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Abstract: Schizophrenia is a collection of psychotic disorders with irregularities in the thought process, which have the feeling that they are controlled by external forces, delusions, perceptual disorders and abnormal effects integrated with real situations or reality. The use of antipsychotics in schizophrenic patients is the treatment of this disease, especially the most commonly used atypical antipsychotic users. This study aims to compare LDL (low-density lipoprotein) levels in schizophrenia patients who use single atypical antipsychotics and combination atypical antipsychotics at Madani Hospital Medan, North Sumatra. This type of research is descriptive analytical using  a cross-sectional  method that takes data on variable-free bound variables at one time, which is housed at the Upt Health Laboratory. North Sumatra Provincial Health Office. The results of the Independent T-Test of the use of single antipsychotics and a combination of atypical antipsychotics on LDL levels in schizophrenia patients were p=0.001 (P≤0.05). There was a significant difference between the administration of a single atypical antipsychotic and a combination of atypical antipsychotics to LDL levels in patients with schizophrenia.
Hubungan Tingkatan Simtom Kecemasan dengan Self-Esteem Pelajar SMA Swasta Muhammadiyah 02 Medan Nathasya Putri Kinanti; Nanda Sari Nuralita; Nurhasanah Nurhasanah; Des Suryani
Jurnal Pengabdian Ilmu Kesehatan Vol. 5 No. 3 (2025): November: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v5i3.5891

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Anxiety is a condition when emotions that arise when individuals are under stress, and is characterized by feelings of tension, thoughts that make individuals feel worried and accompanied by physical responses (heart beat fast, increased blood pressure, and others).1 Anxiety is related to fear and manifests as a future-oriented state of mind consisting of a complex cognitive, affective, physiological, and behavioral response system associated with preparation for anticipated events or circumstances that are considered threatening. Excessive anxiety can interfere with daily activities and be a sign of general anxiety disorder. Self-esteem is one of the main factors of how individuals see themselves or the concept of self and becomes an important determinant in human behavior. Early adolescence is the most decisive period in the formation of self-esteem which is characterized by the emergence of positive or negative self-esteem changes. Method: This type of research is analytic descriptive research with a cross sectional design. This research was conducted by looking at the relationship between the level of anxiety symptoms and self-esteem in students by giving the Beck Anxiety Inventory (BAI) and Rosenberg Self-Esteem Scale (RSES) questionnaires as research measurement tools. In this study using a sample of 90 people, where the sample was divided according to strata as many as 30 samples. Test data in this study using univariate test and bivariate test Chi-Square test. Results: the test results found that there was a relationship between the level of anxiety symptoms on the self-esteem of students of SMA Swasta Muhammadiyah 02 Medan and obtained a significant value of <0.001 (p<0.05). Conclusion: there is a significant relationship between the level of anxiety disorders to self-esteem in students of SMA Swasta Muhammadiyah 02 Medan.
Pencegahan Penyakit Degeneratif dan Faktor Risikonya Isra Thristy; Amelia Eka Damayanti; Nanda Sari Nuralita
IHSAN : JURNAL PENGABDIAN MASYARAKAT Vol 8, No 1 (2026): Ihsan: Jurnal Pengabdian Masyarakat (April)
Publisher : University of Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/ihsan.v8i1.25921

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Penyakit degeneratif, termasuk diabetes, hipertensi, penyakit jantung, dan stroke, telah menjadi salah satu masalah kesehatan utama di Indonesia, seiring dengan perubahan gaya hidup dan peningkatan harapan hidup. Di Indonesia, penyakit degeneratif kini merupakan penyebab utama morbiditas dan mortalitas, menggantikan penyakit menular yang sebelumnya mendominasi. Untuk mengatasi permasalahan penyakit degeneratif di masyarakat, terutama di wilayah seperti Kota Medan, diperlukan pendekatan yang komprehensif dan terintegrasi. Salah satu kegiatan yang dilakukan adalah peningkatan edukasi dan kesadaran masyarakat dan promosi gaya hidup sehat. Metode pendekatan yang digunakan dalam kegiatan ini adalah pendekatan penyuluhan. Tim Pengusul dan mitra bersama-sama menyusun rencana kegiatan, metode, tujuan, sasaran dan target yang harus dicapai. Dari kegiatan ini, didapatkan hasil pengetahuan peserta sebelum edukasi lebih banyak yang masih kurang (62,5%) mengenai penyakit degeneratif dan faktor risikonya dibandingkan setelah mendapatkan edukasi (20,8%). Setelah dilakukan edukasi terjadi peningkatan pengetahuan yang lebih baik (79,2%) dibandingkan sebelumnya (37,5%). Intervensi edukatif seperti ini penting dilakukan secara rutin dan menyeluruh untuk mencegah meningkatnya kasus penyakit degeneratif di Indonesia.
Perbandingan Tingkat Kecemasan pada Siswa yang Terpapar dan Tidak Terpapar Pornografi di SMA X Kota Medan Rara Rizana; Nanda Sari Nuralita
The Journal General Health and Pharmaceutical Sciences Research Vol. 2 No. 4 (2024): December : The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v2i4.473

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Anxiety is an unpleasant feeling, such as excessive worry, fear, and helplessness, which can interfere with daily activities.helplessness, which can interfere with daily activities. In Indonesia,anxiety is ranked as the second highest mental disorder. One of the triggering factor is exposure to pornography, which is now easily accessed by children and adolescents through technological developments. Indonesia ranks third in global pornography access. Research shows that pornography addiction can increase the risk of anxiety by up to 13.5% in adolescents aged 18 years and above. This exposure affects the brain, mental and behavior of children and adolescents. This study used an analytic design observational design with a cross-sectional study approach. The sample consisted of 207students of SMA X Medan City who were selected using the Probability Sampling method with Simple Random Sampling technique.method with Simple Random Sampling technique. Primary data were collected through an online questionnaire online using Google Form.Hasil: Respondents were dominated by students aged 17 years old (60.5%) and the majority were female (67.1%). Level of level of mild anxiety was the most dominant, both in students who were exposed to pornography (24.3%) and those not exposed (32.4%). Statistical analysis statistical analysis showed a significant difference in anxiety levels between students exposed to pornography with those not exposed (P = 0.000; P < 0.05). There is a significant difference in anxiety levels between students exposed to and not exposed to pornography in SMA X Medan City. This finding highlights the importance of prevention and intervention efforts against pornography exposure in exposure to pornography in adolescents to reduce the risk of anxiety.
Gangguan Psikosomatis pada Lansia di Kelurahan Sei Mati Nanda Sari Nuralita; Shiyang Yang Halim
JURNAL IMPLEMENTA HUSADA Vol 5, No 1 (2024)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v5i1.18807

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Psikosomatis adalah penyakit yang melibatkan antara pikiran dan fisik. Hal ini dikarenakan pikiran dapat memengaruhi sistem pada tubuh sehingga akan menimbulkan keluhan ataupun gejala pada fisik. Tujuan sosialisasi pada kegiatan ini ialah untuk menyampaikan pengetahuan dan informasi kepada masyarakat terutama lansia tentang gangguan psikosomatis. Sosialisasi akan dilakukan dengan cara menjelaskan secara langsung kepada masyarakat dengan poster dan membagikan brosur. Gangguan psikosomatis banyak dialami oleh berbagai kalangan baik muda maupun tua. Psikosomatis akan menyerang seseorang yang mengalami dan merespon suatu keadaan secara berlebihan, sehingga akan membuat pikiran negatif yang nantinya memengaruhi sistem tubuh. Faktor yang dapat menyebabkan gangguan psikosomatis berupa gangguan pada psikologis ataupun kejiwaannya, faktor sosial ekonimi, keluarga dan kesehatan.
Correlation of Angiotensin Converting Enzyme (ACE) Gene Polymorphism and Random Blood Sugar Levels In Obese Amelia Eka Damayanty; Isra Thristy; Nanda Sari Nuralita
JURNAL IMPLEMENTA HUSADA Vol 6, No 3 (2025)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v6i3.25281

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Background: Obesity is a condition where there is excessive accumulation of fat that can pose a risk to health in the form of the risk of chronic diseases such as type 2 diabetes mellitus (DM). Current blood sugar levels are one of the diagnoses of type 2 DM (T2DM) which is a standard test that describes blood glucose homeostasis. Angiotensin Converting Enzyme (ACE) is an important enzyme in the renin-angiotensin system (RAS) because it catalyzes the conversion of angiotensin I to angiotensin II (Ang II). The RAS component of adipose tissue provides a potential pathway by which obesity can lead to insulin resistance where ACE gene polymorphisms can raise blood sugar levels. Objectives: To analyse the relationship of ACE gene polymorphism with random blood sugar levels as a predictor of type 2 DM risk in obesity. Materials and Methods: The design of this study was observational analytic with a cross-sectional approach. The sample in this study were blood from 35 obesity people in Universitas Muhammadiyah Sumatera Utara and then carried out PCR examination to identify ACE gene polymorphisms and random blood sugar levels. The data were analyzed with the Kruskal Wallis Test. Results: The major samples were in 26-35 years old (42,86%). The most types of ACE gene polymorphisms were type II 51,4%, followed by the type of ID polymorphisms (32,4%), and the least was the type of DD polymorphisms (10,8%). The random blood sugar levels was normal level 80-140mg/dl (74,29%). The Kruskal Wallis test of ACE gene polymorphism and blood sugar levels with p = 0.119 (p  0.05). Conclusion: There was no correlation of  ACE gene polymorphism with random blood sugar levels in obesity.
Perbedaan Tingkat Depresi pada Orang dengan Skizofrenia Berdasarkan Jenis Kelamin terhadap Lama Pengobatan di Rumah Sakit Madani Medan Gebby Nusantara; Nanda Sari Nuralita
JURNAL IMPLEMENTA HUSADA Vol 4, No 1 (2023)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v4i1.12889

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Latar Belakang: Skizofrenia merupakan kelainan otak kronis yang dapat bergejala pada saat aktif berupa delusi, halusinasi, bicara tidak teratur, kesulitan berpikir, dan kurangnya motivasi. Orang yang menderita skizofrenia sering kali mengalami masalah kesehatan mental lainnya, seperti gangguan kecemasan dan depresi. Orang yang mengalami skizofrenia juga sering mengalami disfungsi sosial, sehingga lebih mungkin menjadi pengangguran, miskin, dan tunawisma. Hal ini menyebabkan penurunan harapan hidup dengan beberapa perkiraan lebih sedikit 10-12 tahun dibandingkan orang yang tidak menderita skizofrenia. Bukti menunjukkan bahwa masalah kesehatan mental seperti depresi lebih buruk pada skizofrenia. Sebagai contoh, depresi adalah faktor paling signifikan dalam bunuh diri pada skizofrenia. Tujuan: Mengetahui perbedaan tingkat depresi skizofrenia berdasarkan jenis kelamin terhadap lama pengobatan di Rumah Sakit Madani Medan. Metode: analitik kategorik dengan rancangan penelitian yang dipakai adalah studi cross sectional, Teknis pengambilan sampel yang digunakan penelitian ini adalah Non Probability Sampling yaitu sampel tidak dipilih secara acak dengan metode Purposive Sampling. Data penelitian ini diperoleh dari data primer menggunakan kuesioner. Analisis data menggunakan uji chi-square. Hasil: Hasil penelitian yang didapatkan bahwa pada laki-laki lama pengobatan 1 tahun 29 orang (33.7%) dan 1 tahun 14 orang (16.3%), pada perempuan lama pengobatan 1 tahun 31 orang (36.0%) dan 1 tahun 12 orang (14%). Hasil analisis antara jenis kelamin terhadap lama pengobatan pada orang dengan skizofrenia adalah p = 0.815 (P0.05). Kesimpulan: Tidak terdapat hubungan yang signifikan antara jenis kelamin terhadap lama pengobatan pada orang dengan skizofrenia.
Dampak Bahan Kimia Berbahaya dalam Makanan terhadap Kesehatan Isra Thristy; Amelia Eka Damayanty; Nanda Sari Nuralita
JURNAL IMPLEMENTA HUSADA Vol 3, No 3 (2022)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v3i3.11846

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Abstrak: Masyarakat telah menggunakan dan mengkonsumsi bahan makanan yang mengandung bahan kimia berbahaya dalam kehidupan sehari-hari. Bahan kimia berbahaya ini apabila menumpuk di dalam tubuh dapat berdampak buruk bagi kesehatan tubuh. Zat adiktif makanan yang dimaksud dalam hal ini adalah pengawet, penyedap, pewarna, pemantap, antioksidan, pengemulsi, pengumpal, pemucat, pengental, dan anti gumpal. Bahan tambahan pangan (BTP) merupakan bahan tambahan yang secara sengaja ditambahkan pada makanan/minuman dengan maksud untuk memperbaiki tampilan makanan/minuman. jenis bahan tambahan pangan golongan pengawet yang dilarang penggunaannya dalam produk pangan antara lain adalah formalin dan asam borat. Metode pelaksanaan yang digunakan dalam kegiatan ini adalah pendekatan melalui penyuluhan atau edukasi dan diakhiri dengan diskusi. Kegiatan tersebut diharapakan dapat meningkatkan kesadaran terhadap masyarakat tentang penggunaan bahan kimia berbahaya maupun bahan aditif makanan khususnya di lingkungan keluarga. Dari hasil kegiatan ini didapatkan terjadi peningkatan pengetahuna masyarakat mengenai bahan kimia yang terkandung dalam makanan, dampaknya dan cara sederhana mendeteksinya yaitu menjadi 76% peserta memiliki pengetahuan baik