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All Journal Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Odonto dental journal Jurnal Ilmiah Sultan Agung Jurnal Pengabdian Masyarakat Dentmas Journal of Fisheries & Marine (Medical Scientific Journal) MESINA
Arlina Nurhapsari
Fakultas Kedokteran Gigi, Universitas Islam Sulan Agung
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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PENGARUH EKSTRAK DAUN PEPAYA (CARICA PAPAYA, LINN.) TERHADAP PENURUNAN INDEKS GINGIVITIS PADA PEMAKAI ALAT ORTODONTIK CEKAT Hafid Nur Arzanudin; Arlina Nurhapsari; Aning Susilowati
Odonto : Dental Journal Vol 2, No 1 (2015): July 2015
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (84.597 KB) | DOI: 10.30659/odj.2.1.34-39

Abstract

Background: Gingivitis is one of the serious periodontal infection desease and if there is no precise treatment it will cause the loss of tooth. Patient with fixed orthodontic appliance will be easier to be suffered by the gingivitis because the form of the appliance that attached in such a way. The gingivitis treatment has some alternatives derived from nature and traditional medicines. One of the plants which can be used as traditional medicine is papaya leaf (carica papaya L). Purpose: This study was conducted to determine the effect of papaya leaf extract toward the decline of gingivitis index in patient with fixed orthodontic appliance.  Method: The method of this research was quasi-experiment with one group pre-post test design which samples were patient with fixed orthodontic appliance. The gingivitis index was examined in the sample which contains of 30 people at before and after treatment. The index was measured by counting gingival amount score devided by the number of teeth examined. The datawere analyzed by using Friedman examination with the degree of significance 0,05. Result: The result of the study shows that before the treatment 56,7% patient with fixed orthodontic appliance have mild gingivitis. And after the treatment, the number of patient with fixed orthodontic appliance with mild gingivitis increase to 93,3%. The significance score based on the Friedman examination was 0,000 (p<0,05). It means there was a meaningful differences between the group which is given papaya leaf extract at before and after the treatment. Conclusion: It can be concluded that papaya leaf extract is able to decrease the gingivitis index of patient with orthodontic appliance
PENGARUH BERBAGAI KONSENTRASI EKSTRAK BIJI ADAS (Foeniculum vulgare mill.) SEBAGAI DENTURE CLEANSER TERHADAP PERTUMBUHAN CANDIDA ALBICANS PADA PLAT AKRILIK Andhika Ambo; Arlina Nurhapsari; Erwid Fatchur Rahman
Odonto : Dental Journal Vol 2, No 2 (2015): December 2015
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.345 KB) | DOI: 10.30659/odj.2.2.62-67

Abstract

Introduction: Fennel plant is known as a medicine plant. Fennel plant parts that have the highest content is the seed. Essential oils, flavonoids, and saponins contained in fennel seed have an influence against candida albicans growth.Purpose: This study was conducted to determine the influence of various concentrations of fennel seed extract as a denture  cleanser against candida albicans growth on acrilyc plate.Methods: This research was an experimental laboratoty and study design was an experimental with post test only control group design. Total sample is 30 acrilyc plate measuring 6x1 cm. The sample were divided into 6 groups, 5 groups were  soaked in various concentrations of fennel seed extract (20%, 40%, 60%, 80%, 100%) and one groups was soaked in control positive polident. Soaking was done for 5 minutes. Candida  albicans were incubated for 48 hours at 37°C. The result of this study were analyzed by one-way ANOVA and LSD (Least  Significance Difference).Results: Based on the one-way ANOVA test was done then  obtained significance value of 0,000 (p<0,05), so it can be concluded that there are significant differences between the two sets groups of at least. Based on the LSD test was done then obtained significance value of p<0,05 in all groups which means there are significant differences between each group, except in group fennel seed extract concentration of 100% with control  positive polident obtained 0,924 significance (p>0,05) which means there are no significant differences between two groups.Conclusion: The researchers' conclusion that there was the influence of various concentration of fennel seed extract as a denture cleanser against candida albicans growth on aclilyc plate. Fennel seed extract concentration of 100% has the  greatest influence as a denture cleanser against candida albicans growth.
PENGARUH PEMBERIAN GEL AIR KELAPA GADING (COCOS CAPITATA) TERHADAP TINGKAT KECEMASAN PADA HIPERSENSITIVITAS DENTIN Studi in vivo terhadap tikus wistar jantan Chariza Hanum Mayvita Iskandar; Yayun Siti Rochmah; Arlina Nurhapsari
Odonto : Dental Journal Vol 3, No 2 (2016): December 2016
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (253.875 KB) | DOI: 10.30659/odj.3.2.133-137

Abstract

Background: Ivory palm water (Cocos capitata) has a high potassium content. Potassium ion can depolarized excited dental nerve on dentin hypersensitivity. This study was to determine the effect of water gel ivory palm against dentine hypersensitivity by the anxiety level of mice using RGS (Rat Grimace Scale).Method: This research has been through ethical clearance which researchmethod was quasy experimental in vivo. The sample was 16 Wistar rats (Rattus novergicus) male 4-5 months with 4 mice in each group. Group I as a positive control. Group II as the ivory palm water gel 10% treatment group. Group III as the ivory palm water gel 70% treatment group. Group IV as a negative control. Research data analysis used Kruskal Wallis test with p <0.05 then continued by Mann Whitney test.Result: Kruskal Wallis test obtained significant difference between the four study groups (p <0.05). Mann Whitney test results in comparison either between positive control group and ivory palm water gel 10% and 70%, and comparison group of ivory palm water gel 10% and 70% weren’t significantly different.Conclusion: This study conclusion there was no significant difference between ivory palm water gel 10 % and 70 % in reducing anxiety level in male Wistar rats with dentinal hypersensitivity
KEBOCORAN TEPI RESIN KOMPOSIT BULK FILL SETELAH APLIKASI BAHAN DESINFEKSI KAVITAS CHLORHEXIDINE DIGLUCONATE 2% DAN ALKOHOL 70% - Study In Vitro Atiek Amalia Ahsanti; Arlina Nurhapsari; M. Dian Firdausy
Odonto : Dental Journal Vol 6, No 1 (2019): July 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (486.582 KB) | DOI: 10.30659/odj.6.0.29-33

Abstract

Background: Caries is a form of tooth decay that is often encountered in daily life. Caries development can be prevented by dental restoration treatments. One such dental restorative material is a bulk fill composite resin with a low shrinkage level. Disinfection is needed to be done before the application of composite restorative materials. The purpose of this research was to know whether there is an microleakage of bulk fill composite resin after application of cavity disinfectionmaterial such as chlorhexidine digluconate 2% and alcohol 70%.Method: This was an experimental research with post test only control group design. The sample of research were 20 premolar teeth. The samples were divided into two groups (10 teeth each group). Group I was applied chlorhexidine digluconate 2% while group II was applied 70% alcohol. Microleakage were measured by observing a methylene blue 2% penetration depth using a metallography microscope.Result: The result indicated the significant differences microleakage of bulkfill composite resin after application of cavity disinfection chlorhexidine digluconate 2% and alcohol 70% from Mann-whitney test 0,039 (<0,05).Conclusion: Microleakage of the bulk fill composite resin was greater in the 70%alcohol than in the chlorhexidine digluconate 2%.
PEMBERDAYAAN MASYARAKAT DESA MARGASARI MENUJU DESA BEBAS KARIES MELALUI PRODUK BERES (BEBAS KARIES) Setyaningrum, Yunita; Nurhapsari, Arlina; Mayangsari, Regilia Shinta; Yuniar, Savira Nurazky; Indrawati, Silvia Vera; Dimas P. P., Muhammad
Jurnal Pengabdian Masyarakat DentMas Vol 1, No 1 (2023): Juni 2023
Publisher : Faculty of Dentistry Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/dentmas.1.1.31-35

Abstract

Background: The Global Burden of Disease Study 2019 estimates that 3.5 billion people worldwide experience dental and oral health problems, with dental caries being the most common disease. The 2018 RISKESDAS data shows that the greatest caries prevalence is in the 5-year-old (93.4%), 12-year- old (68.8%), 15-year-old (68.1%), 35-44 years (92.1%) and 65 years old. -74 years (95.2%). Dental caries has an impact on the quality of life of the sufferer which can interfere with daily activities so that efforts are needed and people become more aware and care about their oral health. Method: The solution to the problem is carried out by educating the community, one of them are in Margasari, Tegal. Dental Health Education is carried out using poster media to make it more interactive, effective and efficient. Evaluation of the implementation is done by using a questionnaire. The results of the questionnaire were tabulated using SPSS with the Wilcoxon non-parametric test method. Result: wilcoxon signed rank shows that there are 0 negative ranks, 24 positive ranks, and 1 ties. Z value based on negative ranks are -4.322 Conclusion: There is an increase in knowledge of respondents after being given education.
PENGARUH BAHAN MEDIKAMEN INTRAKANAL TERHADAP BAKTERI PSEUDOMONAS AERUGINOSA Dewi, Pentha Ayu Kusuma; Nurhapsari, Arlina; Yusuf, Mohammad
MESINA (Medical Scientific Journal) Vol 2, No 1 (2021): Medical Scientific Journal (MESINA)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/msj.v2i1.3295

Abstract

Perawatan saluran akar (PSA) merupakan salah satu perawatan endodontik yang bertujuan untuk membersihkan jaringan pulpa atau mikroorganisme yang terdapat didalam sistem saluran akar. Perawatan saluran akar dapat terjadi kegagalan apabila obturasi tidak sempurna, perforasi akar, overfilling, kista periapikal, dan kebocoran akar. Kegagalan perawatan saluran akar dapat menjadikan pulpa yang nekrosis sebagai habitat bakteri Pseudomonas aeruginosa. Tujuan penelitian ini adalah untuk mengetahui pengaruh tiga bahan medikamen intrakanal terhadap bakteri Pseudomonas Aeruginosa. Penelitian eksperimental laboratorium yang dilakukan dengan rancangan post test only group design dilakukan pada bakteri Pseudomonas aeruginosa yang dikultur dan dibagi menjadi 4 kelompok yang masing-masing diberi Odontopaste 1 mg, Ledermix 1 mg, kalsium hidroksida 1 mg, dan aquades sebagai kontrol negatif. Kemudian hasil dapat dilihat dari zona hambat dan zona bunuh yang diukur menggunakan jangka sorong digital dan data dianalisa dengan One-way Anova dilanjut Post-hoc LSD. Hasil uji One-way Anova sig (p=0.000), yang artinya terdapat pengaruh pemberian bahan medikamen zink oksida, antibiotik pasta, dan kalsium hidroksida terhadap bakteri Pseudomonas aeruginosa. Hasil uji Post-hoc LSD menunjukkan perbedaan rerata zona hambat yang bermakna sig (p<0.05) antar kelompok penelitian. Kesimpulan dari penelitian ini terdapat pengaruh pemberian zink oksida, antibiotik pasta, dan kalsium hidroksida sebagai anti bakteri pada bakteri Pseudomonas.
The Effect of Red Algae (Eucheuma cottonii) Nanoemulgel on Cytokine Il-1 Beta Expression for Traumatic Ulcers Healing Feranisa, Anggun; Nurhapsari, Arlina; Indriastanti, Rikha; Amalina, Rizki
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol. 13 No. 2 (2024): November
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.v13i2.23398

Abstract

Red algae (Eucheuma cottonii) is a type of seaweed (Rhodophyceae). Eucheuma cottonii contains flavonoids and florotanin as an anti-inflammatory agent. The extracted red algae were formulated into nanoemulgel. This study aimed to determine the effect of red algae nanoemulgel (Eucheuma cottonii) in the expression of IL-1β cytokines on the healing of traumatic ulcers. The researcher applied true experimental research with a post-test-only control group design. This research was conducted by giving Eucheuma cottonii nanoemulgel concentrations of 20%, 35%, 50%, positive control, and negative control at the labial once a day, followed by evaluation using the IHC method. The results revealed that Eucheuma cottonii nanoemulgel extract affected the expression of IL-1β cytokines in healing traumatic ulcers by decreasing the amount of IL-1β cytokine expression. The results obtained a p-value of 0.05, which indicates a significant difference in the expression of the number of IL-1β cytokines in traumatic ulcers. This study concluded that the 20% Eucheuma cottonii extract nanoemulgel treatment group affected the amount of IL-1β by decreasing the expression of IL-1β cytokines. Nanoemulgel of 20% Eucheuma cottonii extract is considered effective as an anti-inflammatory material for traumatic ulcer healing.
POTENSI EKSTRAK MENGKUDU (MORINDA CITRIFOLIA L.) SEBAGAI BAHAN ALTERNATIF SALURAN AKAR – A NARRATIVE SYSTEMATIC REVIEW Nurhapsari, Arlina; Setyaningrum, Yunita; Sari, Meilenia Muftika
Jurnal Ilmiah Penelitian Mahasiswa Vol 4, No 2 (2025): JUNI 2025
Publisher : Jurnal Ilmiah Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang: Keberhasilan terapi saluran akar sangat bergantung pada debridemen dan disinfeksi yang efektif, terutama pada area yang tidak dapat dijangkau oleh instrumen mekanis. Meskipun irigan konvensional seperti natrium hipoklorit (NaOCl) dan EDTA efektif, sifat sitotoksik dan potensi erosi dentinnya membatasi penggunaannya. Perhatian yang meningkat telah diberikan pada alternatif berbahan herbal, termasuk Morinda citrifolia (MC), yang dikenal memiliki sifat antimikroba, antiinflamasi, dan antioksidan.Tujuan: Ulasan ini mengevaluasi potensi jus Morinda citrifolia (MCJ) sebagai bahan irigasi saluran akar alternatif.Metode: Tinjauan pustaka dilakukan menggunakan database PubMed, Scopus, ScienceDirect, EBSCO, dan Google Scholar. Artikel yang dipilih berasal dari tahun 2015–2024 dengan kriteria berbasis PICO, yang berfokus pada studi in vitro, ex vivo, dan beberapa studi in vivo terbatas yang menilai MC sebagai bahan irigasi saluran akar.Hasil: MCJ menunjukkan efektivitas antimikroba, khususnya terhadap E. faecalis dan C. albicans, dengan tingkat sitotoksisitas minimal pada konsentrasi 6%. MCJ juga menunjukkan biokompatibilitas terhadap sel hPDLF dan hSCAP, serta mempertahankan ekspresi penanda odontogenik. Dibandingkan dengan EDTA, MCJ lebih mampu mempertahankan kekerasan mikro dentin dan menyebabkan kerusakan struktur yang lebih sedikit. Ketika dikombinasikan dengan EDTA atau XP-Endo Finisher, MCJ meningkatkan penghilangan lapisan smear dan memperkuat kekuatan adhesi sealer.Kesimpulan: MCJ menunjukkan potensi sebagai bahan irigasi endodontik yang biokompatibel. Studi in vivo dan klinis lanjutan diperlukan untuk mengonfirmasi keamanan dan efektivitasnya.Kata Kunci: Endodontik, M. citrifolia, irigasi, antimikroba, biokompatibilitas.
Saltwater Fish Powder for Amelogenesis in Zebrafish Larvae (Danio rerio) Christiono, Sandy; Pradopo, Seno; Hutami, Islamy Rahma; Indasari, Novia; Nurhapsari, Arlina; Rochmah, Yayun Siti Rochmah; Ibrahim, Zurairah; Yuniar, Savira Nurazky; Suparmi
Jurnal Ilmiah Perikanan dan Kelautan Vol. 16 No. 2 (2024): JURNAL ILMIAH PERIKANAN DAN KELAUTAN
Publisher : Faculty of Fisheries and Marine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jipk.v16i2.54677

Abstract

Graphical Abstract Highlight Research 1. The saltwater fish powder is rich in omega3, vitamin D, and calcium which helps tooth amelogenesis. 2. LC50 Toxicity Test was carried out using zebrafish larvae (Danio rerio) with negative control, positive control using 3,4-dichloroanilin, and treatment groups with saltwater fish powder solution in 6 different concentration. 3. No signs of zebrafish embryo mortality or developmental abnormalities on treatment group from the lowest (125μg/ml) nor highest concentration (4000μg/ml). 4. Saltwater fish powder has proven lack of toxicity. Abstract Many nutrients found in saltwater fish are thought to promote amelogenesis in ameloblast cells during tooth development. Although its toxicity is uncertain, saltwater fish powder provided benefits for amelogenesis. Zebrafish embryos have complex metabolic pathways and comprehensive physiological reactions. The LC50 toxicity of saltwater fish powder on zebrafish embryos was investigated in this study. The aim of the of the study is to determine the effect of LC50 toxicity on saltwater fish powder on zebrafish embryos. The experimental research method was a post-test-only control group design, consisting of eight groups, namely the negative control and the internal group using embryo media, the positive control using 3,4-dichloroanillin, and the treatment group 125μg / ml, 250μg / ml, 500μg / ml, 1000μg / ml, 2000μg / ml, and 4000μg / ml using 384 zebrafish embryos. Saltwater fish powder is diluted and observed for 96 hours, controlled every 24 hours. It was found that saltwater fish powder was not toxic because there were no dead zebrafish embryos from various concentrations, negative control, and internal control.
Antibacterial Effectivity of Nanoemulgel Phaleria macrocarpa’s leaf on the Porphyromonas gingivalis ATCC 33277 Biofilm Thickness Pratiwi, Rosa; Ratnawati, Irma Dewi; Ismail, Ade; Nurhapsari, Arlina; Amelia, Rosalita
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.168-174

Abstract

Porphyromonas gingivalis is an oppoturnistic microorganism in periodontal disease that is formed at the stage maturation of biofilm formation. One of the natural materials biofilm reduction is the Phaleria macrocarpa. Phaleria macrocarpa’s leaf contains chemical compounds such as flavonoids, tannins, alkaloids, saponins that function as antibacterials.The aim of this research is to determine the effectiveness of the nanoemulsion of the gel Phaleria macrocarpa’s leaf  on the thickness of the P. gingivalis bacterial biofilm. The research design was carried out with a post test only with a total of 28 samples, then divided into 4 groups of treatment of Phaleria macrocarpa’s leaf extract nanoemulsion gel preparations with variations in concentrations of 30%, 40%, and 50%, as well as a control group of 25% metronidazole gel. The reading of the anti-biofilm thickness test results was measured by OD (Optical density) using an ELISA-reader. One way Anova parametric test among obtained p<0.000 results showing the effect of Phaleria macrocarpa’ leaf gel nanoemulsion extract on the decrease in the thickness of the Porphyromonas gingivalis bacterial biofilm. It can be concluded that the nanoemulsion gel formulation of Phaleria macrocarpa’s leaf extract concentrations of 30%, 40%, and 50% is effective, with a concentration 50% was most effective against reducing the thickness of the bacterial biofilm Porphyromonas gingivalis.
Co-Authors Ade Ismail Ade Ismail A.K Akbar, Davia Kurnia Alphania Esty Luthfaida Amelia, Rosalita Andhika Ambo Andina Rizkia Putri Kusuma Anggun Feranisa Ani Labibah Aning Susilowati Anitalia Sukma Permata Sari Atiek Amalia Ahsanti Balqis Nureska Khomsiana Benni Benyamin Berti Silviana Intani Beti Ratnasari Chariza Hanum Mayvita Iskandar Denis Yusfa Dewi, Pentha Ayu Kusuma Dimas P. P., Muhammad Diyah Fatmasari Erwid Fatchur Rahman Ferry Gustiningrum Grahita Aditya Hafid Nur Arzanudin Helmi Fathurrahman, Helmi Hesty Pradini Ibrahim, Zurairah Indasari, Novia Indrawati, Silvia Vera Indriastanti, Rikha Islamy Rahma Hutami, Islamy Rahma Kris Adityawarman Kusuma, Andina Rizkia P M. Dian Firdausy Mayangsari, Regilia Shinta Mayya Nailullathifah Moh. Baehaqi Mohammad Yusuf, Mohammad Muh. Dian Firdausy Novia Indasari Rahma, Destari Amelia Rahmawati Sri Praptiningsih Rama Putranto Ratnawati, Irma Dewi Recita Indraswary Recita Indraswary Rifqi Wahyu Febrian Rizki Amalina Rizky, Novi Sagita Rochmah, Yayun Siti Rochmah Rochman Mujayanto Rosa Pratiwi, Rosa Rr. Sarah Ladytama Rusna Fiki Kafalia Sandy Christiono Sari, Meilenia Muftika Savira Nurazky Yuniar Seno Pradopo Seno Pradopo Setyaningrum, Yunita shella indri novianty Styaningrum, Yunita Suparmi Suparmi Sutji Asri Tjitra A Syarifah Nur Laili Siyam Uswatun N.A Darjono Widyasari, Ferina Yayun Siti Rochmah Yayun Siti Rochmah Rochmah Yuniar, Savira Nurazky Zurairah Ibrahim