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All Journal Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Majalah Info Sains Journal of Pharmaceutical and Sciences. Jurnal Kefarmasian Indonesia
Lengkey, Yessie
Universitas Kristen Indonesia Tomohon
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Inhibitory Activity Test of Sea Grape (Caulerpa racemosa) Against Salmonella typhi Bacteria Kereh, Indri J.; Lengkey, Yessie K.; Untu, Sonny D.; Ginting, Margaretha S.; Karauwan, Ferdy A.; Tulandi, Selvana S.; Sumagando, Adolfina
Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Vol. 8 No. 1 (2025): April 2025
Publisher : FMIPA UKIT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55724/jbiofartrop.v8i1.500

Abstract

Salmonella typhi is the primary bacterial cause of typhoid fever, which remains a serious health concern in developing countries, including Indonesia. This study aims to evaluate the inhibitory activity of sea grape (Caulerpa racemosa) extract against Salmonella typhi. The extract was obtained through maceration and tested using the agar diffusion method with paper discs at various concentrations (100, 200, 300, and 400 µg/disc). The results showed that C. racemosa extract inhibited the growth of S. typhi with average inhibition zone diameters of 25 mm (100 µg), 27.3 mm (200 µg), 28.8 mm (300 µg), and 29.5 mm (400 µg). The negative control (distilled water) showed no antibacterial activity. Based on classification, all concentrations exhibited very strong antibacterial activity. A higher extract concentration corresponded to greater inhibitory effect. These findings suggest that C. racemosa has potential as a natural antibacterial agent against S. typhi and may be further developed for alternative typhoid treatment.
Co-Authors Aditia Biasa Amal R. GInting Andre R. Usuman Asmuruf, Yunice Delon Sermatang Douglas N. Pareta Einstein Z. Karundeng Etrit Sabenar Febrilia Mangirang Filia Krisna Wilar Fina Feronica Kotangon Friska Mery Montolalu Gabyara Mandey Ginting, Margaretha S. Glaudia Tawi Goni, Jenelitha S. Hariyadi Hariyadi Hariyadi Hariyadi Hariyadi, Hariyadi Indriani Maitulung Irene Alfania Kawung Jabes Wolter Kanter Jacklyne Sumombo Jeane Mongi Julia Brigita Sumonda Kalangi, Jekki J. F. Karauwan, Ferdy Kereh, Indri J. Martina G. Laloan Moningka, Asriani S. Nerni Potolangi Olvie Datu Paat, Vlagia Indira Patricia Sulianti Mona Polii, Ruland Randy Tampa'i Randy Tampa'i Randy Tampa’i Recky A.L. Simatupang Rinny V. Sakul Royke R. Palandi Rudy Pareda Sambou, Christel N. Sasambe Naka Indriyani Sesilia Agata Soriton Silvana L. Tumbel Simanjuntak, Alfared S. Sonny Untu Sony Larumpaa Sumagando, Adolfina Sumombo, Jacklyne Tampa'i, Randy Tesalonika Hermina Mamahit Tombuku, Joke Luis Tri Nugrahani I.M Kilis Tulandi, Selvana Stien Vania V. Liling Wilmar Maarisit