MULYOTO PANGESTU
1. EPRD- Dept. Obstetrics and Gynecology, Monash University, Monash Medical Center,Victoria, Melbourne 2.Lab. Reproductive Physiology, Jenderal Soedirman University, Purwokerto

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Journal : sanus medical journal

Enhancing Reproductive Health and Sexually Transmitted Infection Prevention Awareness through Community Engagement Mustifah, Etty Farida; Ujianti, Irena; Sukarya, Wawang Setiawan; Pangestu, Mulyoto
Sanus Medical Journal Vol. 6 No. 2 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i2.18202

Abstract

ntroduction The Thousand Islands, a popular tourist destination in DKI Jakarta Province, is facing a new challenge, namely the increasing concern about the transmission of Sexually Transmitted Infections (STIs) triggered by the increase in tourism visits. In response to this issue, a community service activity was carried out by the Faculty of Medicine at UHAMKA. Objective The aim of this activity is to raise awareness and knowledge in the community, particularly among educators in the Thousand Islands, about the dangers of and prevention against STIs and the importance of Reproductive Health Education. Method The partners in this community service activity are teachers in the Thousand Islands. A total of 30 teachers were involved in this training. The methods used involve training and counseling that incorporate direct training and open discussions. Data were collected through observations and field notes. Results The results of this activity include an increase in understanding and skills of teachers concerning Reproductive Health Education and STI prevention, which they can apply in educating students. Additionally, it was found that community awareness about the dangers of STIs also increased as a direct result of this activity. Conclusion The conclusion that can be derived from this activity is that appropriate education and training on reproductive health and the prevention of STIs for the community, specifically educators, can be an effective strategy in controlling STI transmission in tourist areas like the Thousand Islands. This activity also helps to strengthen the local health system in dealing with the challenge of STI transmission.
Terapi TB Paru Kasus Baru MTB Not Detected Disertai Peningkatan Fungsi Hati: Laporan Kasus Apriliana, Dian; Putri, Dewi Novita; Pangestu, Mulyoto
Sanus Medical Journal Vol. 6 No. 2 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i2.18201

Abstract

Tuberculosis (TB) is caused by Mycobacterium tuberculosis and can infect various organs, including the lungs and extrapulmonary. Standard treatment uses anti-TB drugs (OAT) such as rifampicin, isoniazid, ethambutol, and pyrazinamide, which can cause hepatotoxic side effects or Drug-Induced Liver Injury (DILI). This study aims to analyze the incidence of DILI in TB patients receiving OAT FDC therapy. The method used is a case study on a 24-year-old patient who experienced nausea, vomiting, and jaundice after receiving FDC therapy. Laboratory examinations showed increased ALT and AST, indicating DILI. Data were analyzed with periodic monitoring of liver enzymes and clinical changes. The results showed that temporary cessation of OAT and administration of hepatoprotective curcuma supplements were effective in improving liver function. This study suggests routine liver enzyme examination in patients receiving OAT therapy to prevent DILI. Alternative OAT therapy can be considered in patients with severe DILI.   Tuberkulosis (TBC) disebabkan oleh Mycobacterium tuberculosis dan dapat menginfeksi berbagai organ, termasuk paru dan ekstra paru. Pengobatan standar menggunakan obat anti-TBC (OAT) seperti rifampisin, isoniazid, ethambutol, dan pyrazinamid, yang dapat menyebabkan efek samping hepatotoksik atau Drug-Induced Liver Injury (DILI). Penelitian ini bertujuan untuk menganalisis kejadian DILI pada pasien TBC yang menerima terapi OAT FDC. Metode yang digunakan adalah studi kasus pada pasien berusia 24 tahun yang mengalami mual, muntah, dan ikterus setelah menerima terapi FDC. Pemeriksaan laboratorium menunjukkan peningkatan ALT dan AST, yang mengindikasikan DILI. Data dianalisis dengan pemantauan berkala enzim hati dan perubahan klinis. Hasil menunjukkan bahwa penghentian sementara OAT dan pemberian suplemen hepatoprotektor curcuma efektif dalam perbaikan fungsi hati. Penelitian ini menyarankan pemeriksaan rutin enzim hati pada pasien yang menerima terapi OAT untuk mencegah DILI. Alternatif terapi OAT dapat dipertimbangkan pada pasien dengan DILI berat.