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The Association of Age, Parity, and History of Cesarean Section with the Occurrence of Placenta Accreta Spectrum (Pas) at H. Adam Malik Hospital in Medan 2020-2022 Siagian, Beby Febyola; Pasaribu, Hotma Partogi; Kusumawati, R. Lia; Daulay, Rini Savitri
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 1 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i1.14935

Background: Maternal mortality rate (MMR) is an indicator of the quality of midwifery services in a country. Postpartum hemorrhage is a serious life-threatening complication and the main cause of maternal death especially that caused by placenta accreta spectrum (PAS). This study aims to determine the relationship between age, parity, and history of cesarean section on the incidence of PAS at H. Adam Malik Hospital Medan in 2020-2022.Method: This study was an analytic-observational study with a cross-sectional design. The data used came from the medical records, including information about the population of mothers who gave birth, maternal age at delivery, parity, and previous history of cesarean section. Statistical analysis used univariate and bivariate chi-square tests.Result: The study subjects were 84 people selected by simple random sampling method. The results of the univariate analysis showed the highest frequency of age >32 years, parity 3-4 times, and a history of cesarean section â‰¥ 2. The results of bivariate analysis showed a significant relationship between age and the incidence of PAS (p=0.016), parity and the incidence of PAS (p<0.001), and a history of cesarean section and the incidence of PAS (p=0.004).Conclusion: There is a relationship between age, parity, and history of cesarean section with the incidence of PAS at H. Adam Malik Hospital Medan in 2020-2022.

Factors Influencing Tuberculosis Infection in Children with Close Contact of Adult Pulmonary Tuberculosis Patients Mayasri, Fadhliani; Dalimunthe, Wisman; Sianturi, Pertin; Amelia, Rina; Daulay, Rini Savitri; Meirina, Fathia
Jurnal Keperawatan Priority Vol. 8 No. 2 (2025)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v8i2.6647

This research aims to determine the factors that influence tuberculosis infection in children with close contact with adult pulmonary tuberculosis sufferers. This research is an analytical observational study with a consecutive sampling method at the Glugur Darat Health Center in November 2024 until January 2025. Bivariate analysis using chi-square to determine whether there is a relationship between the independent and dependent variables. The type of test used is the Fisher Exact and Kruskal Wallis Test. There is no multivariate test because there are no significant variables in the bivariate test. In total, in 42 samples there were 10 children with positive Mantoux tests. Of the 23 female children there were 7 (30.4%) with positive results and of the 19 male children there were 3 (15.8%) positive results. Of the 39 children with a history of BCG immunization, there were 10 (25.6%) with tuberculosis infection. Of the 37 children with parents whose income was <UMR, 10 children (27%) had tuberculosis infection. 37 children whose parents had junior high school education, 9 people (24.3%) had tuberculosis infection. 10 children aged 1-5 years and 6-10 years, there were 2 (20%) each with tuberculosis infection. 26 children aged 11-18 years, there were 6 people (27.3%) with tuberculosis infection. There was no significant relationship between age, gender, immunization status, nutritional status, parental income and parental education level in this research.

Age and Diabetes Mellitus Associated with Hematological Disorders and Peripheral Neuropathy in MDR-TB Patients Treated with the BPaL/M Regimen Tako, Frida Welhelmina; Sinaga, Bintang Yinke Magdalena; Harahap, Juliandi; Daulay, Rini Savitri; Siregar, Jelita; Samodra, Yoseph Leonardo
Jurnal Respirasi Vol. 11 No. 3 (2025): September 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.3.2025.241-249

Introduction: Tuberculosis (TB) is a disease with a significant treatment burden. Current multidrug-resistant (MDR)-TB therapy uses the bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL/M) combination. This combination is effective with a short treatment duration. Linezolid is one of the components of the BPaL/M regimen. However, despite its effectiveness, it has side effects that impact treatment management and success. This study aimed to find the association between characteristics and comorbidities with the incidence of linezolid side effects in patients with MDR-TB treated with the BPaL/M regimen. Methods: This was a retrospective analytic study of MDR-TB patients receiving BPaL/M combination. Data were collected from medical records and analyzed using Fisher's exact test to analyze the association between patient characteristics and comorbidities with the incidence of linezolid side effects, namely hematological disorders, peripheral neuropathy, and visual disturbances. Results: There was no significant association between overall patient characteristics and the incidence of linezolid adverse events. However, the results of bivariate analysis showed a significant association in age >50 years old with the incidence of hematological disorders, as well as in patients who have diabetes mellitus (DM) with the incidence of peripheral neuropathy as a side effect of linezolid. Conclusion: Monitoring of MDR-TB patients aged >50 years old and those with DM to minimize the incidence of side effects during treatment is essential. This effort is expected to support the success of the national TB control and treatment program.

Factors Influencing Tuberculosis Infection in Children with Close Contact of Adult Pulmonary Tuberculosis Patients Mayasri, Fadhliani Putri; Dalimunthe, Wisman; Sianturi, Pertin; Amelia, Rina; Daulay, Rini Savitri; Meirina, Fathia
Jurnal Keperawatan Priority Vol. 8 No. 2 (2025)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v8i2.6647

This research aims to determine the factors that influence tuberculosis infection in children with close contact with adult pulmonary tuberculosis sufferers. This research is an analytical observational study with a consecutive sampling method at the Glugur Darat Health Center in November 2024 until January 2025. Bivariate analysis using chi-square to determine whether there is a relationship between the independent and dependent variables. The type of test used is the Fisher Exact and Kruskal Wallis Test. There is no multivariate test because there are no significant variables in the bivariate test. In total, in 42 samples there were 10 children with positive Mantoux tests. Of the 23 female children there were 7 (30.4%) with positive results and of the 19 male children there were 3 (15.8%) positive results. Of the 39 children with a history of BCG immunization, there were 10 (25.6%) with tuberculosis infection. Of the 37 children with parents whose income was <UMR, 10 children (27%) had tuberculosis infection. 37 children whose parents had junior high school education, 9 people (24.3%) had tuberculosis infection. 10 children aged 1-5 years and 6-10 years, there were 2 (20%) each with tuberculosis infection. 26 children aged 11-18 years, there were 6 people (27.3%) with tuberculosis infection. There was no significant relationship between age, gender, immunization status, nutritional status, parental income and parental education level in this research.

Relationship between Age and the Occurrence of Depression Symptoms in Children with Acute Lymphoblastic Leukemia Riano, Dwika Intania; Tanjung, Ika Citra Dewi; Malisie, Ririe Fachrina; Wahyuni, Arlinda Sari; Siregar, Olga Rasiyanti; Daulay, Rini Savitri
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6230

In children and adolescents, depressive symptoms often presenting as irritability, anhedonia, or behavioral changes. Despite significant advancements in survival rates due to improved therapeutic protocols, the psychological burden experienced by children with ALL.Objective: To evaluate the relationship between age and the presence of depressive symptoms in children diagnosed with ALL.Methods: A cross-sectional study was done using consecutive sampling with 40 children aged from 7 to 18 years old acquired, conducted from August to October 2024 at the outpatient unit of Adam Malik Hospital, Medan. Forty children aged 7–18 years with a confirmed diagnosis of ALL were included. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Categorical variables were analyzed using the chi-square test, followed by bivariate to identify significant predictors of depression.Results: Among the 40 participants, the most age group were children ≤ 10 years old (65%). A statistically significant association was found between age group and the presence of depressive symptoms (p = 0.001, OR= 33,3). Conclusions: Age is significantly associated with the severity and presence of depressive symptoms in pediatric patients with ALL. Older children were more likely to report higher levels of depression. Psychological evaluation and targeted mental health support may be especially important in older age groups.

Hubungan Pengetahuan dan Tindakan dengan Kejadian Malaria di Wiayah Kerja Puskesmas Pulau Tello Kecamatan Pulau-Pulau Batu Kabupaten Nias Selatan Mendrofa, Yeni Christina; Siregar, Jelita; Harahap, Juliandi; Daulay, Rini Savitri; Adriztina, Indri
MAHESA : Malahayati Health Student Journal Vol 6, No 4 (2026): Volume 6 Nomor 4 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i4.21923

ABSTRACT Malaria still poses a global and national health problem, with 511,548 cases in Indonesia in 2024; a significant spike occurred in South Nias Regency, which recorded 1,267 cases and 13 deaths, where the Puskesmas Pulau Tello reported 408 cases and 5 deaths after previously reporting no cases since 2020. A preliminary survey in Sifitu Ewali Village showed that 15 out of 20 residents still associate the cause of malaria with mystical factors, reflecting a low level of knowledge and possibly contributing to the high incidence rates. X The purpose of this research is to analyze the relationship between community knowledge and actions with the incidence of malaria in the working area of the Pulau Tello Health Center, Batu Islands District, South Nias Regency. This study is an observational analytical quantitative study with a case control design conducted from April to June 2025 in the working area of the Puskesmas Pulau Tello, South Nias District. The sample consisted of 55 cases (malaria patients) and 55 controls (non-malaria sufferers), selected through simple random sampling and matched based on age and village domicile. Data were collected through a questionnaire to measure knowledge and action levels, as well as secondary data from the Puskesmas concerning malaria status. Analysis was performed bivariately using chi-square tests with a p-value 0.05 and odds ratio (OR) calculations to assess the strength of the relationship between variables. There is a significant relationship between knowledge and actions with the incidence of malaria (p-value = 0.0001 for both). Individuals with good knowledge have a much lower risk of contracting malaria (OR = 0.065; 95% CI: 0.023–0.178), while individuals with poor preventive actions have almost 6 times higher risk of contracting malaria (OR = 5.961; 95% CI: 2.614–13.590). This research shows that community knowledge and actions are significantly related to the occurrence of malaria; good knowledge can reduce the risk, while poor preventive actions significantly increase the risk of contracting malaria. Therefore, it is recommended to improve education and outreach to the community about malaria and encourage the implementation of good preventive measures, such as the use of mosquito nets, maintaining environmental cleanliness, and access to healthcare services, in order to reduce the incidence of malaria. Keywords: Malaria, Knowledge, Action, Islands. ABSTRAK Malaria masih menjadi masalah kesehatan global dan nasional, dengan 511.548 kasus di Indonesia pada tahun 2024; lonjakan signifikan terjadi di Kabupaten Nias Selatan yang mencatat 1.267 kasus dan 13 kematian, dimana Puskesmas Pulau Tello melaporkan 408 kasus dan 5 kematian setelah sebelumnya nihil kasus sejak 2020. Survei pendahuluan di Desa Sifitu Ewali menunjukkan bahwa 15 dari 20 warga masih mengaitkan penyebab malaria dengan faktor mistik, yang mencerminkan rendahnya tingkat pengetahuan dan kemungkinan berkontribusi terhadap tingginya angka kejadian. Tujuan penelitian ini adalah penelitian ini adalah untuk menganalisis hubungan pengetahuan dan tindakan masyarakat dengan kejadian malaria di wilayah kerja Puskesmas Pulau Tello, Kecamatan Pulau-Pulau Batu, Kabupaten Nias Selatan. Penelitian ini merupakan studi kuantitatif observasional analitik dengan desain case control yang dilakukan pada April hingga Juni 2025 di wilayah kerja Puskesmas Pulau Tello, Kabupaten Nias Selatan. Sampel terdiri dari 55 kasus (penderita malaria) dan 55 kontrol (tidak menderita malaria), yang dipilih secara simple random sampling dan dimatching berdasarkan usia serta domisili desa. Data dikumpulkan melalui kuesioner untuk mengukur tingkat pengetahuan dan tindakan, serta data sekunder dari Puskesmas untuk status malaria. Analisis dilakukan secara bivariat menggunakan uji chi-square dengan p-value 0,05 dan perhitungan odds ratio (OR) untuk menilai kekuatan hubungan antara variabel. Terdapat hubungan yang signifikan antara pengetahuan dan tindakan dengan kejadian malaria (p-value= 0,001 untuk keduanya). Individu dengan pengetahuan yang baik memiliki risiko jauh lebih rendah terkena malaria (OR = 0,065; 95% CI: 0,023–0,178), sementara individu dengan tindakan pencegahan yang kurang baik memiliki risiko hampir 6 kali lebih tinggi terkena malaria (OR = 5,961; 95% CI: 2,614–13,590). Penelitian ini menunjukkan bahwa pengetahuan dan tindakan masyarakat berhubungan signifikan dengan kejadian malaria; pengetahuan yang baik dapat menurunkan risiko, sedangkan tindakan pencegahan yang kurang baik meningkatkan risiko terkena malaria secara signifikan. Oleh karena itu, disarankan untuk meningkatkan edukasi dan penyuluhan kepada masyarakat tentang malaria serta mendorong penerapan tindakan pencegahan yang baik, seperti penggunaan kelambu, menjaga kebersihan lingkungan, dan akses terhadap layanan kesehatan, guna menekan angka kejadian malaria. Kata Kunci: Malaria, Pengetahuan, Tindakan, Pulau

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