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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Public Health of Indonesia Jurnal Respirasi (JR) Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Jurnal Kedokteran Meditek
Sinaga, Bintang Yinke Magdalena
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Factors Affecting the Quality of Life Among Pulmonary Tuberculosis Patients at the TB-DOTS Outpatient Clinic of Public Hospital Zahra, Diandra Angelia Az; Sinaga, Bintang Yinke Magdalena
Public Health of Indonesia Vol. 10 No. 1 (2024): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v10i1.774

Abstract

Background: Indonesia is the second country in the world with the highest burden of tuberculosis. Pulmonary tuberculosis is one of the global health issues that can substantially affect quality of life. Objective: To analyze the quality of life and associated factors among pulmonary tuberculosis patients. Methods: A cross-sectional study was conducted at the TB-DOTS outpatient clinic of Prof. Chairuddin Panusunan Lubis Universitas Sumatera Utara Hospital, Medan, Indonesia. The study subject was 100 pulmonary tuberculosis patients aged ≥18 years, newly diagnosed, and undergoing treatment from August to October 2023, selected using consecutive sampling. Primary data were collected through face-to-face interviews using the WHOQOL-BREF questionnaire. Descriptive statistics, the chi-square test, and the logistic regression test were used for data analyses. Results: The chi-square test showed there was a significant relationship between age (p = 0.022), family income (p = 0.005), treatment phase (p < 0.001), and adverse drug reactions (p = 0.040) with overall quality of life. The logistic regression test showed there was a significant relationship between family income (p = 0.007, OR = 3.685, 95% CI = 1.432–9.479) and treatment phase (p < 0.001, OR = 5.643, 95% CI = 2.139–14.888) with the deterioration of overall quality of life. Conclusion: The treatment phase lasting less than 2 months was the factor that most influenced the deterioration of the overall quality of life. Hence, families, healthcare workers, and the government should consider the treatment phase as a focus of interventions to enhance the quality of life of pulmonary tuberculosis patients
Perianal Fistula Due to Tuberculosis Infection: A Case Report Sinaga, Bintang Yinke Magdalena; Siagian, Novi Andriani; Siagian, Parluhutan; Muhar, Adi Muradi
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 3 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i3.15613

Abstract

Introduction: Approximately 5% of all cases of tuberculosis are extrapulmonary. A rare extrapulmonary variant of the disease is known as perianal tuberculosis, which accounts for 0.001% of all extrapulmonary tuberculosis cases. Case Report: A 28-year-old male presented with intermittent chronic anal pain and purulent discharge from the anal for 6 months, without respiratory complaints. Chest X-Ray examination shows minimal infiltrate on the right lung apex and broncho vascular pattern partially covered with infiltrate. Fistulotomy has been done three times in this patient within 6 months. Colonoscopy examination shows recti polyp, and the histopathology result from biopsy specimen taken from the last fistulotomy is tuberculosis-specific chronic inflammatory process. The Human Immunodeficiency Virus test is negative. This patient has been treated with anti-tuberculosis treatment for 7 months and 2 months after consuming it the wound on the perianal is healing and the patient’s weight is gaining 10 kgs within 7 months. Conclusion: The diagnosis of perianal tuberculosis is challenging, especially in the absence of pulmonary focus. Tuberculosis should be considered in the differential diagnosis of perianal ulcers and fistulas, mainly in non-healing and recurrent anal lesions, especially in regions where tuberculosis is endemic. Management with anti-tuberculosis treatment can provide complete recovery.
Clinical Spectrum and Factors Associated to Post Covid Syndrome in Healthcare Workers Sinaga, Joshua Princeman; Sinaga, Bintang Yinke Magdalena; Siagian, Parluhutan; Eyanoer, Putri Chairani; Samodra, Yoseph Leonardo
Public Health of Indonesia Vol. 10 No. 4 (2024): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v10i4.844

Abstract

Background:Post-COVID Syndrome (PCS) is a newly recognized condition reported by approximately 45% of individuals following COVID-19 infection. This syndrome is estimated to affect the health-related quality of life in 10–30% of affected individuals. Objective:To examine the characteristics of Post-COVID Syndrome among healthcare workers at Adam Malik Hospital. Methods:This study employed a cross-sectional descriptive design. Data were collected using structured questionnaires administered to healthcare workers at Adam Malik Hospital who had contracted COVID-19 between 2020 and 2022. Results:A total of 120 participants were included in the study. The sample was predominantly female (78.3%), with the youngest age group (19–30 years) comprising 37.5% of participants. Most participants had direct exposure to patient care (78.3%) and were confirmed COVID-19 positive in 2021 (42.5%). Notably, 45.0% of participants were unvaccinated, 20.9% had a history of hospitalization, and 78.3% experienced mild COVID-19 infections. Hypertension was identified as the most common comorbidity. Participants were categorized as experiencing Acute PCS (43.9%) or Chronic PCS (56.1%), with both groups exhibiting similar predominant symptoms, including fatigue, persistent cough, memory impairment, and cognitive difficulties. Statistically significant associations were identified between PCS and variables such as sex (p=0.004, OR=0.27), age (p=0.015, OR=4.46), severity of prior COVID-19 infection (p=0.040, OR=1.77), vaccination status (p<0.001, OR=3.82), and the presence of comorbidities (p=0.025, OR=2.53). Conclusion:Post-COVID Syndrome is characterized by multifactorial etiologies and heterogeneous clinical manifestations. Factors such as gender, age, vaccination status, comorbid conditions, and severity of prior infections were significantly associated with PCS outcomes. Gender-related differences, potentially influenced by immune response, hormonal mechanisms, and antibody production, appear to contribute to variations in PCS manifestations. These findings underscore the need for further research to elucidate the epidemiology, clinical presentations, and pathological mechanisms underlying this emerging post-viral condition.  Keywords:Post-COVID Syndrome; healthcare workers; COVID-19; clinical manifestations; post-viral sequelae
Contributing Factors of Anxiety on Healthcare Workers during COVID-19 Pandemic at Referral Hospital of Sumatra Region in Indonesia Simanjuntak, Christine Raphaela Tiarmauli; Sinaga, Bintang Yinke Magdalena; Siagian, Parluhutan; Effendy, Elmeida; Zaluchu, Fotarisman
Public Health of Indonesia Vol. 11 No. S1 (2025): Special Issue
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11iS1.888

Abstract

Background:During the Coronavirus Disease 2019 (COVID-19) pandemic, nurses and doctors served as the frontline healthcare workers. Consequently, mental health issues among healthcare workers can develop into significant health problems and impose a substantial social burden, particularly on nurses and doctors working in hospital settings. Objective:To analyze the prevalence and factors influencing anxiety levels among healthcare workers, specifically nurses and doctors, at Adam Malik General Hospital Medan during the COVID-19 pandemic. Methods:This study employed a cross-sectional design with bivariate analysis. Data were collected using the DASS-42 questionnaire, which was distributed to 114 participants comprising nurses and doctors working in both the COVID-19 emergency isolation and ward isolation units. Results:The findings revealed that 29 participants (25.4%) exhibited symptoms of anxiety, with the majority experiencing mild anxiety (13.2%). The nursing profession demonstrated the highest prevalence of anxiety disorders, with 33.3% of nurses reporting symptoms. Being a nurse was significantly associated with higher anxiety levels compared to being a doctor, and working in the emergency isolation room was significantly associated with higher anxiety levels compared to working in the isolation ward or both units (p<0.05). Conclusion:Factors such as gender, marital status, parental status, post-COVID-19 status, family history of COVID-19, vaccination history, and comorbidities did not significantly affect anxiety levels among healthcare workers during the COVID-19 pandemic at Adam Malik General Hospital Medan. However, anxiety was prevalent among healthcare workers, with nurses and those working in the emergency isolation room being particularly affected. Keywords:anxiety; COVID-19; healthcare workers; mental health; Indonesia
Relationship between Transaminase Enzyme Levels and Severity of Dengue Fever Sidabutar, Wita Lestari; Saragih, Restuti Hidayani; Rohmawati, Lili; Sinaga, Bintang Yinke Magdalena
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol. 25 No. 1 (2025): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v25i1.22076

Abstract

Since dengue hemorrhagic fever (DHF) can cause liver damage, aminotransferase levels as liver function test may be useful in predicting the severity of dengue hemorrhagic fever. The purpose of this study was to determine the relationship between transaminase enzyme levels and the severity of dengue hemorrhagic fever. This study used analytic observational approach with cross-sectional design. The data used was secondary data, namely medical records of H. Adam Malik Hospital and Hospital of Prof. Dr. Chairuddin P. Lubis University of North Sumatera. From a total of 65 patients included, there were 63.1% (41 patients) with DHF grade 1, 29.2% (19 patients) were DHF grade 2, 6.2% (4 patients) were DHF grade 3 and 1.5% (1 medical record) were DHF grade 4. For aminotransferase level 56.9% (37 records) had elevated SGPT levels and 92.3% (60 records) had elevated SGOT levels, it was found that there was no relationship between increased levels of SGPT and SGOT with the severity of DHF (SGPT p = 0.628 and SGOT p = 1.00). There is no association between the elevations of transaminase enzyme levels and the severity of DHF.
Nutritional Status of Kindergarten Children in Medan Helvetia Subdistrict and the Factors Affecting It Pasaribu, Ira Nurhasanah; Wijaya, Hendri; Sinaga, Bintang Yinke Magdalena; Yunita, Rina
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 2 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i2.18618

Abstract

Background: During childhood, especially from toddlerhood to school age, children experience significant body growth. Therefore, children require an adequate concentration of nutrients per kilogram of body weight. Low nutritional status affects the quality of human resources because it affects intelligence and resistance to disease. The aim of the study was to analyse the factors that contribute to the nutritional status of kindergartens in Medan Helvetia Sub-district. Methods. This study was a quantitative analytic study using a cross sectional approach. The study population was kindergartens in Medan Helvetia Subdistrict with a sample of 100 people. The sampling technique in this study used a stratified random sampling method. Data collection method was questionnaire method using questionnaire and 24-hour food recall and anthropometric measurement using weighing tool and microtoise. Data analysis using chi square and fisher’s exact test. Results. Of 100 children, it was known that 58 was female, 42 children was male, 29 children was < 60 months old, 64 children was 60 to 72 months old, 7 children is > 72 months old. 1 child has poor nutritional status, 29 children was found with malnutrition, 57 had good nutritional status, 9 had an overnutrition status, while 4 children was obese. Bivariate analysis of food intake with a p value = 0.004; family income with a p value = 0.672; maternal insight with a p value = 0.234; infectious diseases with a p value = 0.030; immunization status with a p value = 0.399; maternal education level with a p value = 0.092. Conclusion. Factors that influence the nutritional status of kindergarten children in Medan Helvetia Sub-district are food intake and infectious diseases.
Age and Diabetes Mellitus Associated with Hematological Disorders and Peripheral Neuropathy in MDR-TB Patients Treated with the BPaL/M Regimen Tako, Frida Welhelmina; Sinaga, Bintang Yinke Magdalena; Harahap, Juliandi; Daulay, Rini Savitri; Siregar, Jelita; Samodra, Yoseph Leonardo
Jurnal Respirasi Vol. 11 No. 3 (2025): September 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.3.2025.241-249

Abstract

Introduction: Tuberculosis (TB) is a disease with a significant treatment burden. Current multidrug-resistant (MDR)-TB therapy uses the bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL/M) combination. This combination is effective with a short treatment duration. Linezolid is one of the components of the BPaL/M regimen. However, despite its effectiveness, it has side effects that impact treatment management and success. This study aimed to find the association between characteristics and comorbidities with the incidence of linezolid side effects in patients with MDR-TB treated with the BPaL/M regimen. Methods: This was a retrospective analytic study of MDR-TB patients receiving BPaL/M combination. Data were collected from medical records and analyzed using Fisher's exact test to analyze the association between patient characteristics and comorbidities with the incidence of linezolid side effects, namely hematological disorders, peripheral neuropathy, and visual disturbances. Results: There was no significant association between overall patient characteristics and the incidence of linezolid adverse events. However, the results of bivariate analysis showed a significant association in age >50 years old with the incidence of hematological disorders, as well as in patients who have diabetes mellitus (DM) with the incidence of peripheral neuropathy as a side effect of linezolid. Conclusion: Monitoring of MDR-TB patients aged >50 years old and those with DM to minimize the incidence of side effects during treatment is essential. This effort is expected to support the success of the national TB control and treatment program.
Profil Hemoglobin, Trombosit, dan Rasio Neutrofil Limfosit pada Pasien Kanker Kolorektal: Studi Deskriptif di RSUP Haji Adam Malik Medan Simatupang, Ruth Vanessa; Katharine; Sinaga, Bintang Yinke Magdalena; Abdillah, Hafaz Zakky
Jurnal Kedokteran Meditek Vol 31 No 5 (2025): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i5.3488

Abstract

Introduction: Colorectal cancer is a global health problem with an increasing incidence. Monitoring cancer stage is crucial as it is closely related to therapeutic decisions, prognosis, and patient survival. Simple hematological parameters, such as hemoglobin, platelet count, and neutrophil-to-lymphocyte ratio, may aid in clinical evaluation. Objective: This study aimed to describe the profiles of hemoglobin, platelet count, and neutrophil-to-lymphocyte ratio in patients with colorectal cancer. Methods: The study employed a descriptive observational method with a cross-sectional approach. Secondary data were obtained from the medical records of 141 patients using the total sampling method. Data analysis was performed using descriptive statistics.  Results: Anemia was found in 83% of patients, with a higher incidence at higher stages. Normal platelet counts were observed in 80% of patients, with decreasing proportions in higher stages. Elevated NLR was found in 78% of patients and was more frequent at higher stages of disease.  Conclusion: These findings indicate the presence of anemia and a systemic inflammatory response, but not thrombocytosis. This research highlights the potential of these simple biomarkers in monitoring cancer stages and treatment strategies.  
Factors Associated with Treatment Outcome of Shorter Treatment Regimen (STR) for MultiDrug-Resistant Tuberculosis (MDR-TB) Perangin-angin, Gwanita Nawariantina; Sinaga, Bintang Yinke Magdalena; Siagian, Parluhutan; Eyanoer, Putri Chairani
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 4 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i4.16123

Abstract

ABSTRACT Background: Indonesia ranked 2nd around the world for TB cases with case population continue increasing. In 2018, Shorter Treatment Regimen (STR) was introduced as a new regimen for treating MDR-TB patient. The aim of this study is to determine factors associated with treatment outcome of MDR-TB patients treated with Shorter Treatment Regimen Methods: This is a descriptive-analytic study using cross sectional design which was conducted at Adam Malik Hospital Medan. Subject was 150 patients with drug-resistant Pulmonary TB at MDR-TB polyclinics according to inclusion and exclusion criteria Results: MDR-TB patients that treated with STR was mostly < 50 years old (65.2%) and 107 subjects (70.4%) were male. The majority of subjects with comorbidity were 94 subjects (61.8%); 43 subjects (28.3%) with DM, 5 subjects (3.3%) with CHF, 3 subjects (2.0%) with HIV, 1 subject (0.7%) with DM & CHF, and 1 subject (0.7%) with DM & HIV. When evaluated the patients treatment outcome, 47.4% were cured, 6.6% were failed, 34.8% were default and 11.2% were death. A chi square test was conducted to assess association between age with treatment outcome. Age was significantly associated with treatment outcome (p=0.038) but gender and comorbidity were not associated with treatment outcome with p-value 0.152 and 0.497 (p>0,05) respectively. Conclusions: There is a significant association between age and treatment outcome but no significant association between gender and comorbidity with treatment outcome. ABSTRAK Latar Belakang: Indonesia menduduki peringkat ke-2 dunia untuk kasus TBC dengan populasi kasus yang terus meningkat. Pada tahun 2018, Shorter Treatment Regimen (STR) diperkenalkan sebagai rejimen baru untuk mengobati pasien TB-MDR. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berkorelasi dengan hasil pengobatan pasien TB-MDR yang diobati dengan Regimen STR. Metode: Penelitian ini merupakan penelitian deskriptif-analitik dengan desain cross-sectional yang dilakukan di Rumah Sakit Adam Malik Medan. Subyek penelitian adalah 150 pasien TB Paru Resisten Obat di poliklinik TB MDR sesuai kriteria inklusi dan eksklusi. Hasil: Pasien TB-MDR yang diobati dengan STR sebagian besar berusia <50 tahun (65,2%) dan berjenis kelamin laki-laki sebanyak 107 subjek (70,4%). Mayoritas subjek dengan penyakit penyerta sebanyak 94 orang (61,8%); 43 orang (28,3%) DM, 5 orang (3,3%) CHF, 3 orang (2,0%) HIV, 1 orang (0,7%) DM & CHF, dan 1 orang (0,7%) DM & HIV. Hasil pengobatan adalah 47,4% sembuh, 6,6% gagal, 34,8% putus berobat dan 11,2% meninggal. Uji chi square dilakukan untuk menilai hubungan antara usia dengan hasil pengobatan dan didapatkan nilai p = 0,038 yang menunjukkan adanya hubungan yang signifikan namun berdasarkan jenis kelamin dan penyakit penyerta ditemukan nilai p masing-masing 0,152 dan 0,497 (p>0,05) yang menunjukkan tidak ada hubungan antara jenis kelamin dan penyakit penyerta terhadap hasil pengobatan. Kesimpulan: Terdapat hubungan yang signifikan antara usia dan hasil pengobatan namun tidak ada hubungan yang signifikan antara jenis kelamin dan penyakit penyerta dengan hasil pengobatan.
FACTORS AFFECTING SUCCESSFUL PULMONARY TUBERCULOSIS TREATMENT AT STABAT HEALTH CENTER IN LANGKAT DISTRICT Nahdhia; Sinaga, Bintang Yinke Magdalena; Adriztina, Indri; Saragih, Rina Amalia Caromina; Nasution, Tetty Aman
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 4 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i4.21244

Abstract

Background: Pulmonary Tuberculosis (TB) is a significant global public health problem, mainly affecting the lungs. Many factors are associated with the successful treatment of pulmonary TB patients. This study aims to analyze factors affecting the successful treatment of pulmonary TB at Stabat Health Center, Langkat District. Method: This observational analytic study used a cross-sectional design and was conducted from October 2024 to January 2025 at Stabat Health Center. All pulmonary TB patients diagnosed between 2022 and 2023 who met the inclusion and exclusion criteria were included using a total sampling approach. Data were collected from the Tuberculosis Information System and analyzed using univariate, bivariate, and multivariate analyses. Results: Comorbid diabetes mellitus (DM) (p=0.003; OR=7.01) and distance to health facility (p=0.022; OR=4.44) were significantly associated with treatment success. In contrast, age, sex, occupation, comorbid HIV infection, and treatment status did not show a statistically significant association with treatment outcomes. Conclusion: Comorbid DM had the greatest effect on successful of pulmonary TB treatment at Stabat Health Center. TB patients with Diabetes Mellitus comorbid need special attention. Further research is needed to analyze other potential factors.
Co-Authors Abdillah, Hafaz Zakky Elmeida Effendy Fotarisman Zaluchu, Fotarisman Harahap, Juliandi Hendri Wijaya, Hendri Indri Adriztina Katharine Muhar, Adi Muradi Nahdhia Nasution, Tetty Aman Parluhutan Siagian Pasaribu, Ira Nurhasanah Perangin-angin, Gwanita Nawariantina Putri Chairani Eyanoer, Putri Chairani Restuti Hidayani Saragih Rina Yunita Rini Savitri Daulay, Rini Savitri Rohmawati, Lili Samodra, Yoseph Leonardo Saragih, Rina Amalia Caromina Siagian, Novi Andriani Sidabutar, Wita Lestari Simanjuntak, Christine Raphaela Tiarmauli Simatupang, Ruth Vanessa Sinaga, Joshua Princeman Siregar, Jelita Tako, Frida Welhelmina Zahra, Diandra Angelia Az