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Formulasi body scrub dari kombinasi temu putih (Curcuma zedoaria) dan biji kurma (Phoenix dactylifera) Yuliawati, Yuliawati; Elisma, Elisma; Utami, Diah Tri; Pratiwi, Puspa Dwi
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.456

Abstract

Body scrub is a cosmetic form that removes dead skin cells caused by free radicals from various pollutants and ultraviolet (UV) radiation so skin cells become more accessible to regenerate. White turmeric (Curcuma zedoaria) and date seeds (Phoenix dactylifera) are plants that contain bioactive compounds to maintain and nourish the skin and have antioxidant activity. Besides, date seeds also have the potential as exfoliating agents to facilitate the release of dead skin cells. This study aimed to formulate a body scrub containing ethanol extract of white turmeric rhizome and date seed powder with five types of formulas (K+, K-, F1, F2, F3). This type of research is a true experimental, which includes the formulation and stability test. The stability test was conducted with the Cycling test method in 6 cycles (1 cycle for 2x24 hours) at temperatures of -4oC and 40oC and four months for stability at room temperature. Parameters observed include organolepticity, homogeneity, dispersibility, adhesion, pH, and viscosity. The results showed that this body scrub did not show any change in the organoleptic character, homogeneity, spreadability, adhesion, or pH values that met the requirements of a body scrub preparation. Viscosity met the requirement for stability test for room temperature in four months. This study concludes that the combination of ethanol extract of white turmeric rhizome and date seed powder seeds can be formulated to be a body scrub dosage form.
FRAP REDUCING ACTIVITY OF PROTIUM JAVANICUM BURM.FIL LEAVES: A SCREENING ANTIOXIDANT POTENCY OF NATURAL COSMETIC INGREDIENT Sulastri, Novi; Gemantari, Baiq Maylinda; Hayaza, Azzam Hafid; Azim, Muhlisun; Hariadi, Puspawan; Pratiwi, Puspa Dwi
Indonesian Journal of Cosmetics Vol. 3 No. 2 (2025): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v3i2.2373

Abstract

Tenggulun (Protium javanicum Burm.fil) has been traditionally used to treat various ailments such as cough, stomachache, diarrhea, inflammation and headache. The leaves have therapeutic roles in the treatment and prevention of illnesses acting as antibacterial, antidiabetic and antiinflammation agents. It is also reported that tenggulun leaves can be used for insecticides, cosmetics and food additives. This research aimed to determine antioxidant activity by reducing FRAP of the tenggulun leaves methanol extract using Trolox as the standard solution. The result showed that the tenggulun leaves extract contained secondary metabolites of flavonoid and polyphenolic. The extract showed the FRAP reducing activity at 0,008634±0.00043 μmol TE/g DW. These results indicated the ability of tenggulun methanolic extract to reduce Fe (III) into Fe (II) equivalent to Trolox by the presence of secondary metabolites confirmed.
Program Edukasi Kosmetik Aman pada Siswa MAN 1 Kota Jambi Pratiwi, Puspa Dwi; Yuliawati , Yuliawati; Maharini , Indri; Maimum, Maimum; Fitrianingsih, Fitrianingsih; Syamsurizal, Syamsurizal; Pondawinata, Marizki
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 7 No. 1 (2026): Edisi Januari - April
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Program edukasi kosmetik aman pada siswa MAN 1 Kota Jambi dilaksanakan sebagai upaya meningkatkan pemahaman remaja mengenai pemilihan dan penggunaan produk kosmetik yang memenuhi standar keamanan. Kegiatan ini dilatarbelakangi oleh maraknya peredaran kosmetik ilegal dan kurangnya literasi siswa terkait identifikasi kosmetik berizin edar, kandungan berbahaya, serta risiko kesehatan akibat penggunaan produk yang tidak sesuai. Metode pelaksanaan meliputi pretest, penyuluhan interaktif, demonstrasi cara memeriksa izin BPOM, dan post test untuk menilai peningkatan pengetahuan. Hasil kegiatan menunjukkan adanya peningkatan signifikan pada pemahaman siswa mengenai kriteria kosmetik aman (p <0,001). Selain itu, siswa menunjukkan antusiasme tinggi terkait pemilihan kosmetik yang digunakan untuk sehari-hari. Program ini membuktikan bahwa edukasi yang bersifat aplikatif dan sesuai konteks remaja dapat meningkatkan kesadaran dalam memilih kosmetik yang aman dan legal. Kegiatan ini diharapkan dapat menjadi model edukasi berkelanjutan yang dapat diterapkan di sekolah guna mendukung perilaku penggunaan produk kosmetik yang bertanggung jawab di kalangan remaja.
Uji Aktivitas Sediaan Gel Berbasis Ekstrak Daun Kayu Manis (Cinnamomum burmannii) sebagai Agen Antiinflamasi pada Model Tikus Putih Jantan dengan Induksi Karagenan Kasmadi, Fathnur Sani; Putri, Azelia; Pratiwi, Puspa Dwi; Humaryanto, Humaryanto; Ekaputri, Tia Wida
Jurnal Ilmiah Pharmacy Vol 13, No 1 (2026)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v13i1.917

Abstract

Inflamasi merupakan mekanisme pertahanan fisiologis tubuh yang berperan dalam membatasi perluasan kerusakan jaringan, menekan pertumbuhan mikroorganisme patogen, serta memfasilitasi proses perbaikan jaringan yang mengalami cedera akibat suatu kondisi patologis. Proses ini tergolong respon biologis normal sebagai bagian dari sistem proteksi tubuh. Salah satu tanaman yang diketahui memiliki aktivitas dalam penyembuhan luka adalah daun kayu manis, yang dilaporkan mengandung berbagai metabolit sekunder yaitu fenolik, flavonoid, saponin, steroid, dan tanin yang berkontribusi dalam modulasi proses inflamasi. Formulasi ekstrak daun kayu manis dalam bentuk gel bertujuan untuk meningkatkan penetrasi zat aktif kejaringan target serta memberikan efek pendingin (cooling effect) yang mendukung proses penyembuhan inflamasi. Penelitian ini dilakukan untuk mengevaluasi aktivitas antiinflamasi sediaan gel ekstrak daun kayu manis serta menentukan konsentrasi yang paling optimal dalam menghasilkan efek terapeutik. Metode yang digunakan adalah penelitian eksperimental dengan desain post test only control group. Kelompok perlakuan dibagi menjadi 5 yaitu kontrol positif, kontrol negatif, formula I (ekstrak 2,5%), formula II (ekstrak 5%, dan formula III (ekstrak 10%) yang diaplikasikan secara topikal pada area punggung tikus yang telah diinduksi dengan karagenan 1%. Perlakuan dilakukan selama 4 hari parameter yang diamati berupa volume eksudat dan profil diferensiasi leukosit dalam darah. Hasil penelitian menunjukkan bahwa formulasi gel ekstrak daun kayu manis dengan konsentrasi 10% memberikan aktivitas antiinflamasi paling optimal yang dibuktikan dengan mampu menurunkan volume eksudat. Efektivitas terbaik di tunjukkan dengan nilai persen inhibisi inflamasi pada kosentrasi 10% adalah sebesar 89,47%.
Green-Synthesized Silver Nanoparticles Using Erythrina subumbrans Leaf Extract: Optimization and Antibacterial Activity Maharini, Indri; Utami, Karen Putri; Rachmawati, Lilis; Fitrianingsih, Fitrianingsih; Pratiwi, Puspa Dwi
Sciences of Pharmacy Volume 5 Issue 2
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0502580

Abstract

The high prevalence of acne and increasing antibiotic resistance necessitate the development of sustainable antimicrobial agents. This study investigated the green synthesis of silver nanoparticles (AgNPs) using Erythrina subumbrans (Hassk.) Merr. leaf extract as a natural bioreductant and stabilizer. The primary objective was to optimize the synthesis process and evaluate the antibacterial efficacy of the resulting nanoparticles specifically against Propionibacterium acnes. Physicochemical and structural characterization were performed using spectroscopic and microscopic techniques to confirm the formation and stability of the nanoparticles. The results successfully demonstrated the synthesis of crystalline, nanoscale AgNPs with plant-derived functional groups facilitating their stabilization. Analytical data indicated a relatively uniform particle size distribution, spherical morphology, and favorable surface characteristics, suggesting high suitability for biomedical integration. Significantly, the synthesized AgNPs exhibited potent antibacterial activity against P. acnes. The underlying mechanism of action is attributed to the disruption of bacterial cell membranes, induction of intracellular reactive oxygen species, and subsequent interference with vital cellular functions. Utilizing E. subumbrans extract offers an eco-friendly, cost-effective, and sustainable alternative to conventional chemical synthesis, reducing the reliance on toxic reagents. These findings highlight the significant potential of plant-mediated AgNPs as innovative antimicrobial agents for dermatological applications. This research provides a robust foundation for the advancement of nanotechnology-based topical treatments. Consequently, further investigation into pharmaceutical formulation development, comprehensive safety assessments, and clinical efficacy trials is highly recommended to establish E. subumbrans-mediated silver nanoparticles as viable therapeutic solutions for managing acne and other skin-related infections in the future.