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Formulasi body scrub dari kombinasi temu putih (Curcuma zedoaria) dan biji kurma (Phoenix dactylifera) Yuliawati, Yuliawati; Elisma, Elisma; Utami, Diah Tri; Pratiwi, Puspa Dwi
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.456

Abstract

Body scrub is a cosmetic form that removes dead skin cells caused by free radicals from various pollutants and ultraviolet (UV) radiation so skin cells become more accessible to regenerate. White turmeric (Curcuma zedoaria) and date seeds (Phoenix dactylifera) are plants that contain bioactive compounds to maintain and nourish the skin and have antioxidant activity. Besides, date seeds also have the potential as exfoliating agents to facilitate the release of dead skin cells. This study aimed to formulate a body scrub containing ethanol extract of white turmeric rhizome and date seed powder with five types of formulas (K+, K-, F1, F2, F3). This type of research is a true experimental, which includes the formulation and stability test. The stability test was conducted with the Cycling test method in 6 cycles (1 cycle for 2x24 hours) at temperatures of -4oC and 40oC and four months for stability at room temperature. Parameters observed include organolepticity, homogeneity, dispersibility, adhesion, pH, and viscosity. The results showed that this body scrub did not show any change in the organoleptic character, homogeneity, spreadability, adhesion, or pH values that met the requirements of a body scrub preparation. Viscosity met the requirement for stability test for room temperature in four months. This study concludes that the combination of ethanol extract of white turmeric rhizome and date seed powder seeds can be formulated to be a body scrub dosage form.
Bahan Tambahan dalam Sediaan Tablet: Review Pratiwi, Puspa Dwi; Citrariana, Shesanthi; Gemantari, Baiq Maylinda
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.17472

Abstract

Tablets are solid pharmaceutical dosage form without or with suitable excipients by press or compression manufacturing process. The excipient chosen can influence the product performance (physical properties and stability) and bioavailability. All excipients must be optimally selected to get the optimal formula of tablet dosage form. This article review aims to overview of excipient in tablet dosage form and their role in formulating tablet dosage form. this review article was written based on literature studies from electronic databases such as PubMed, ScienceDirect, and Google Scholar which contain related information using keyword in Indonesian or English use article published in 2013-2023. excipients in tablet dosage form are fillers or diluents, disintegrants, lubricants, preservatives, flavors, sweeteners, coloring, and coating agents. These excipients added to tablet dosage form to facilitating the process of manufacture tablet dosage form, increasing stability and effectiveness of active pharmaceutical ingredients in tablet. The conclusion of this review, there are many classification of tablet excipients which is different function to get compendial requirements of tablet dosage form.
Aplikasi Simplex Lattice Design untuk Optimasi Emulgator dalam Krim Minyak Atsiri Kulit Jeruk Manis Pratiwi, Puspa Dwi; Arnas, Deah Lestiana
Sinteza Vol. 4 No. 2 (2024): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i2.26539

Abstract

In order to obtain a perfect emulsified and stable preparation, choosing the right composition emulsifier is crucial. Formula optimization is needed to determine the best combination of ingredients in formulation process based on evaluation responses. Simplex Lattice Design (SLD) is an experimental design method for mixing materials with the proportion of the total number of materials 1 or 100%. This research was aims to obtained the optimal cream formula using tween 80 and span 80 as emulsifiers and determined their effect on the physical properties of cream preparation. SLD method was used as optimization method with tween 80 and span 80 as independent variables and pH, viscosity, spreadability, and stickiness as responses. The minimum limit for tween 80 and span 80 is 1% (w/v) and the maximum is 9% (w/v) with total 10%. The optimal formula was obtained from consideration of the response by entering the target value to obtain a formula with desirability value close to 1. There are 5 formulas based on SLD recommendations, with a concentration ratio of tween 80 and span 80 9:1 (run 1); 7:3 (run 2); 1:9 (run 3); 5:5 (run 4); and 3:7 (run 5). The relationship between concentration and response value can be explained based on the significance of the model and equations obtained. The optimal formula was the concentration ratio of tween 80 and span 80 8.6:1.34 with a desirability value of 0.953. The conclusion of this research was that SLD can be used to optimize the emulsifier with response predictions close to the results obtained.
FRAP REDUCING ACTIVITY OF PROTIUM JAVANICUM BURM.FIL LEAVES: A SCREENING ANTIOXIDANT POTENCY OF NATURAL COSMETIC INGREDIENT Sulastri, Novi; Gemantari, Baiq Maylinda; Hayaza, Azzam Hafid; Azim, Muhlisun; Hariadi, Puspawan; Pratiwi, Puspa Dwi
Indonesian Journal of Cosmetics Vol. 3 No. 2 (2025): Indonesian Journal of Cosmetics
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/ijcos.v3i2.2373

Abstract

Tenggulun (Protium javanicum Burm.fil) has been traditionally used to treat various ailments such as cough, stomachache, diarrhea, inflammation and headache. The leaves have therapeutic roles in the treatment and prevention of illnesses acting as antibacterial, antidiabetic and antiinflammation agents. It is also reported that tenggulun leaves can be used for insecticides, cosmetics and food additives. This research aimed to determine antioxidant activity by reducing FRAP of the tenggulun leaves methanol extract using Trolox as the standard solution. The result showed that the tenggulun leaves extract contained secondary metabolites of flavonoid and polyphenolic. The extract showed the FRAP reducing activity at 0,008634±0.00043 μmol TE/g DW. These results indicated the ability of tenggulun methanolic extract to reduce Fe (III) into Fe (II) equivalent to Trolox by the presence of secondary metabolites confirmed.
Program Edukasi Kosmetik Aman pada Siswa MAN 1 Kota Jambi Pratiwi, Puspa Dwi; Yuliawati , Yuliawati; Maharini , Indri; Maimum, Maimum; Fitrianingsih, Fitrianingsih; Syamsurizal, Syamsurizal; Pondawinata, Marizki
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 7 No. 1 (2026): Edisi Januari - Maret
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Program edukasi kosmetik aman pada siswa MAN 1 Kota Jambi dilaksanakan sebagai upaya meningkatkan pemahaman remaja mengenai pemilihan dan penggunaan produk kosmetik yang memenuhi standar keamanan. Kegiatan ini dilatarbelakangi oleh maraknya peredaran kosmetik ilegal dan kurangnya literasi siswa terkait identifikasi kosmetik berizin edar, kandungan berbahaya, serta risiko kesehatan akibat penggunaan produk yang tidak sesuai. Metode pelaksanaan meliputi pretest, penyuluhan interaktif, demonstrasi cara memeriksa izin BPOM, dan post test untuk menilai peningkatan pengetahuan. Hasil kegiatan menunjukkan adanya peningkatan signifikan pada pemahaman siswa mengenai kriteria kosmetik aman (p <0,001). Selain itu, siswa menunjukkan antusiasme tinggi terkait pemilihan kosmetik yang digunakan untuk sehari-hari. Program ini membuktikan bahwa edukasi yang bersifat aplikatif dan sesuai konteks remaja dapat meningkatkan kesadaran dalam memilih kosmetik yang aman dan legal. Kegiatan ini diharapkan dapat menjadi model edukasi berkelanjutan yang dapat diterapkan di sekolah guna mendukung perilaku penggunaan produk kosmetik yang bertanggung jawab di kalangan remaja.