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FORMULASI DAN UJI ANTIBAKTERI SEDIAAN SABUN CAIR EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava L) DENGAN BASIS MINYAK KELAPA TERHADAP BAKTERI Staphylococcus aureus tohir, fauzha muftia; ahwan, ahwan; Qonitah, Fadilah
Jurnal Farmasi Sains dan Teknologi Vol. 3 No. 01 (2025): Jurnal Farmasi Sains dan Teknologi
Publisher : PC Ikatan Apoteker Indonesia (IAI) Karanganyar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65117/x33p6m60

Abstract

The use of extracts from medicinal plants in the community is used to prevent diseases, maintain body freshness and treat diseases. Guava leaves (Psidium guajava L) contain active compounds such as tannins, triterpenoids, flavonoids, saponins, alkaloids, and essential oils that have antibacterial effects. This study aims to determine the antibacterial activity of liquid soap ethanol extract of guava leaves against Staphylococcus aureus bacteria. The liquid soap formula of guava leaf extract (Psidium guajava L) is made into 4 formulas F0 (0%), F1(5%), F2(10%), and F3(15%). Antibacterial activity is seen from the antibacterial activity test using the diffusion method. Physical testing of guava leaf ethanol extract liquid soap includes organoleptic, pH, foam height, homogeneity, and viscosity. The results of the study showed that the entire formula qualified for good physical properties and could inhibit the growth of Staphylococcus aureus. The results of the antibacterial activity test showed that guava leaf extract soap (Psidium guajava L) had an inhibition in the formula F0 of 0.00±0.00 mm (no antibacterial activity), F1 of 4.60±0.46 mm (weak antibacterial activity), F2 of 5.27±0.06 mm (moderate antibacterial activity), F3 of 5.93±0.32 mm of moderate antibacterial activity) and a positive control of 11.77±1.46 mm (strong antibacterial activity). Based on the results of the study, it was concluded that the liquid soap formula of guava leaf extract (Psidium guajava L) has good physical properties and shows antibacterial activity against Staphylococcus aureus, and does not differ significantly (p<0.05). 
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI MARKISA UNGU (Passiflora edulis Sims) TERHADAP Propionibacterium acnes: ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT OF PURPLE PASSION FRUIT SEEDS (Passiflora edulis Sims) AGAINST Propionibacterium acnes Rifani, Inesta; Ariastuti, Reni; Qonitah, Fadilah
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/3413qz27

Abstract

Inflammation of the hair follicles and sebaceous glands causes acne, a common skin disorder often triggered by bacterial infections such as Propionibacterium acnes. This study aims to determine the antibacterial activity of an ethanolic extract of purple passion fruit seeds against Propionibacterium acnes. The extraction process was carried out by maceration using 96% ethanol. The antibacterial activity of the extract was tested using the disk diffusion method (Kirby-Bauer) at concentrations of 10%, 20%, and 30%, with positive control (clindamycin) and negative control (1% DMSO) for comparison. Antibacterial activity was measured based on the inhibition zone diameter. The data obtained were then statistically analyzed using a one-way ANOVA test with a 95% confidence level. The extract yield was 5.78% and contained chemical compounds such as flavonoids, alkaloids, tannins, saponins, and terpenoids. The antibacterial test results showed inhibition zones for the 10%, 20%, and 30% extract concentrations and the positive control (clindamycin) of (6.45 ± 1.86) mm (moderate activity), (10.38 ± 0.29) mm (strong activity), (12.21 ± 1.21) mm (strong activity), and (17.78 ± 0.55) mm, respectively. Statistically, there was a significant difference in antibacterial activity between the samples (p-value < 0.05). In conclusion, the ethanolic extract of passion fruit seeds possesses antibacterial properties effective against Propionibacterium acnes..   Keywords: antibacterial, seed, Passiflora edulis Sims, Kirby_bauer, acne
POTENSI HAND SANITIZER EKSTRAK ETANOL BUNGA GLETANG (TRIDAX PROCUMBENS.L) SEBAGAI ANTIBAKTERI TERHADAP STAPHYLOCOCCUS AUREUS Qonitah, Fadilah; Valerie Novia Ramadhani, Feby; Ahwan
FARMESTRA: Jurnal Pelayanan dan Teknologi Kefarmasian Indonesia Vol. 3 No. 02 (2025): Farmestra: Jurnal Pelayanan dan Teknologi Kefarmasian Indonesia
Publisher : Melekliterasi Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66340/c4wphx13

Abstract

The gletang flower is a plant with potential for development as a hand sanitizer. The gletang flower contains compounds such as flavonoids, alkaloids, saponins, tannins, and phenols, which have been shown to inhibit the growth of Staphylococcus aureus bacteria. This study aims to determine the statistical data and antibacterial effects of hand sanitizers made from gletan flower ethanol extract on the growth of Staphylococcus aureus bacteria. The hand sanitizer was prepared with gletan flower ethanol extract in four formulas: Formula 0, Formula 1, Formula 2, and Formula 3. Testing of the physical properties of the hand sanitizer included organoleptic testing, homogeneity, pH, viscosity, and spreadability. The antibacterial activity was tested using the disc test method, and the data was analyzed using the Kruskal-Wallis test. The results of the study show that all formulations exhibit good physical properties and antibacterial activity. The antibacterial activity of the positive control was measured with an average inhibition zone of 9.8 ± 0.52 mm. Formula 1 yielded an average inhibition zone of 9.2 ± 0.05 mm, followed by Formula 2 with 12.06 ± 0.07 mm and Formula 3 with 14.25 ± 0.31 mm. The negative control showed no inhibition zone of 0 ± 0.00 mm. The conclusion of this study is that all three formulas of the hand sanitizer made from gletang flower ethanol extract exhibit good physical properties and have been shown to have antibacterial activity against Staphylococcus aureus, with significant differences.
Tingkat Kepatuhan Minum Obat Pasien Tuberculosis Rawat Jalan di RSUD Soehadi Pridjonegoro Kabupaten Sragen Khusna, Khotimatul; Amalina, Syahida Ulya; Qonitah, Fadilah
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p42-50

Abstract

Tuberculosis (TB) is a contagious infectious disease that is still a global health problem, with Indonesia as one of the countries with the highest cases. The success of TB therapy is highly dependent on patient compliance in taking anti-tuberculosis drugs (OAT) regularly. Factors that influence the level of medication compliance in pulmonary TB patients are gender, age, occupation, education, family support, and drug side effects. This study aims to determine the level of compliance of patients taking outpatient pulmonary TB medication at Soehadi Pridjonegoro Regional Hospital, Sragen Regency. This research uses a descriptive method with a quantitative approach. The sample used in the research was 97 respondents. Sampling using techniques purposive sampling. Data was taken using a validated questionnaire created based on the MARS questionnaire (Medication Adherence Rating Scale). The results of the study showed that patients with a high level of compliance were 65 respondents with a percentage of (67%) and moderate compliance was 32 respondents with a percentage of (33%). The conclusion of this research is that patients take outpatient pulmonary TB medication at Soehadi Pridjonegoro Hospital, Sragen Regency with a high level of compliance (67%) with a total of 65 respondents.
Pemanfaatan Mesin Padder dalam Upaya Meningkatkan Efisiensi Produksi Batik di UMKM Batik Cahaya Baru, Kabupaten Semarang Qonitah, Fadilah; Ariastuti, Reni; Oktaviana Trisna Dewi, Anita; Suwardi, Suwardi; Monika, Dina
Jurnal Abdi Masyarakat Indonesia Vol 6 No 1 (2026): JAMSI - Januari 2026
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.2263

Abstract

UMKM Batik Cahaya Baru di Kabupaten Semarang menghadapi tantangan dalam meningkatkan kualitas dan efisiensi produksi kain batik, khususnya dalam proses pewarnaan kain batik. Pada UMKM ini proses pewarnaannya masih manual sehingga memerlukan waktu yang cukup lama dan tenaga kerja yang intensif. Pengabdian masyarakat ini bertujuan meningkatkan efisiensi produksi batik di UMKM Batik Cahaya Baru melalui pemanfaatan mesin padder untuk pewarnaan kain. Pengabdian masyarakat ini dilakukan dengan edukasi pemanfatan mesin padder dan pelatihan pengoperasian mesin padder dengan baik. Hasil dari pengabdian ini menunjukkan bahwa penggunaan mesin padder dapat meningkatkan efisiensi waktu produksi sebesar 75% serta efisiensi penggunaan larutan pewarna kain batik sebesar 33,33%. Kegiatan ini menunjukkan urgensi pemanfaatan mesin padder sebagai inovasi yang mampu mempercepat proses produksi, mengurangi pemborosan bahan pewarna dan mendukung keberlanjutan usaha UMKM Batik Cahaya Baru.
Pemberdayaan Kelompok Wanita Tani Desa Karangasem dalam Pengelolaan Limbah Minyak Jelantah (Mijel) Guna Mendukung Lingkungan Bersih dan Ekonomi Kreatif Ariastuti, Reni; Qonitah, Fadilah; Patandung, Rosliana; Pambudi, Risma Sakti
Jurnal Pengabdian Kesehatan Vol 9, No 2 (2026): Jurnal Pengabdian Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/jpk.v9i2.624

Abstract

Aktivitas rumah tangga seringkali menghasilkan sampah/limbah, salah satuya aktivitas menggoreng dapat menghasilkan limbah minyak jelantah. Minyak jelantah (mijel) merupakan minyak bekas penggorengan yang banyak mengandung radikal bebas, sehingga berbahaya bagi kesehatan jika digunakan /dikonsumsi terus-menerus, serta memberikan dampak negatif pada lingkungan yang dapat menyebabkan saluran kran pembuangan menjadi mampat dan mencemari tanah. Kegiatan PkM dilakukan dengan tujuan ingin mengurangi limbah mijel dengan memanfaatkannya menjadi lilin aromaterpi dan sabun cuci batangan. Metode pendekatan yang digunakan adalah melalui sosialisasi terkait limbah mijel dan pelatihan cara pengolahan mijel menjadi lilin dan sabun. Hasil pengabdian terlihat tingkat pengetahuan dan ketrampilan ibu-ibu kelompok wanita tani desa Karangasem menjadi meningkat dari tingkat pengetahuan kurang menjadi tingkat pengetahuan baik. Wanita tani desa Karangasem mampu membuat lilin aromaterapi dan sabun dengan baik. Pemanfaatan minyak jelantah menjadi lilin aromaterapi dan sabun dapat mengurangi limbah/sampah rumah tangga, menjaga lingkungan tetap bersih dan mampu menghasilkan produk olahan mijel yang memiliki nilai ekonomi.   
Pemanfaatan Minyak Jelantah Sebagai Bahan Baku Lilin Aromaterapi Ramah Lingkungan Di Kelurahan Karangasem Ariastuti, Reni; Ardistafani , Chintya Rahma; Ariyanti, Debi; Apot, Kornelia Bariap; Qonitah, Fadilah; Patandung, Rosliana
JURNAL PENGABDIAN TEKNOLOGI TEPAT GUNA Vol 7 No 1 (2026): Teknologi Tepat Guna (TTG)
Publisher : Universitas Sahid Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47942/jpttg.v7i1.2191

Abstract

Abstrak: Limbah minyak jelantah masih menjadi isu lingkungan dan kesehatan di masyarakat karena sering dibuang ke saluran air atau digunakan kembali tanpa pengolahan yang tepat, sehingga berpotensi mencemari tanah dan air serta membahayakan kesehatan. Pengabdian kepada masyarakat ini berfokus pada pengelolaan limbah minyak jelantah menjadi lilin aromaterapi sebagai upaya edukasi lingkungan dan pemberdayaan ekonomi masyarakat. Tujuan kegiatan ini adalah menganalisis proses pengolahan minyak jelantah menjadi lilin aromaterapi, mengidentifikasi manfaat ekonomi dan lingkungan, serta memberikan rekomendasi pengelolaan limbah minyak jelantah di masyarakat. Metode pengabdian menggunakan pendekatan edukatif dan partisipatif melalui sosialisasi, penyuluhan, dan pelatihan praktik langsung, disertai evaluasi menggunakan pretest dan posttest. Hasil kegiatan menunjukkan bahwa sebelum pelatihan peserta belum memahami bahaya minyak jelantah dan pemanfaatannya. Setelah kegiatan, peserta mengalami peningkatan pengetahuan dan keterampilan, mampu menjelaskan dampak lingkungan minyak jelantah, serta mempraktikkan pembuatan lilin aromaterapi secara mandiri. Kegiatan ini meningkatkan kesadaran lingkungan dan membuka peluang usaha rumah tangga berkelanjutan. Kata Kunci: (Minyak Jelantah, Masyarakat, Lilin Aromaterapi, Pengabdian Masyarakat)
Uji Aktivitas Tabir Surya Ekstrak Etanol Kulit Markisa Ungu secara In Vitro dengan Spektrofotometri Uv-Vis Agtri, Nisa Aulia; Ariastuti, Reni; Qonitah, Fadilah
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.20601

Abstract

Excessive exposure to Ultraviolet (UV) radiation can cause skin damage, including erythema, premature ageing, and skin cancer. Sunscreen is commonly used to protect the skin from UV radiation. The peel of purple passion fruit (Passiflora edulis) contains phenolic and flavonoid compounds that may provide UV-absorbing activity. This study aimed to evaluate the sunscreen activity of the ethanol extract of purple passion fruit peel in vitro based on the Sun Protection Factor (SPF), Erythema Transmission Percentage (%Te), and Pigmentation Transmission Percentage (%Tp). The extract was obtained by maceration with 96% ethanol. Qualitative identification of phenolic compounds was performed using a FeCl3 reagent, while flavonoids were detected using concentrated HCl and magnesium powder. Sunscreen activity was evaluated using UV-Vis spectrophotometry at concentrations of 400, 600, 800, 1,000, and 1,200 ppm. The results showed that the extract contained phenolic and flavonoid compounds. At the highest concentration (1,200 ppm), the SPF value was 20.086±1.696 (ultra-protection), %Te was 0.697±0.149, and %Tp was 4.413±0.594, all of which were categorised as sunscreen. One-way ANOVA analysis indicated significant differences among concentration variations (p<0.05). In conclusion, the ethanol extract of purple passion fruit peel has potential as a natural active ingredient for sunscreen.