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All Journal Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ JFL : Jurnal Farmasi Lampung Kumawula: Jurnal Pengabdian Kepada Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian Sainstech Farma: Jurnal Ilmu Kefarmasian Jurnal Kesehatan Tambusai JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Jurnal Abdimas Bina Bangsa FASKES : Jurnal Farmasi, Kesehatan, dan Sains Parapemikir Jurnal Ilmiah Farmasi Sociality: Journal of Public Health Service Jurnal Farmasi Sains dan Teknologi FARMESTRA
Fadilah Qonitah
Sebelas Maret University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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FORMULASI DAN UJI ANTIBAKTERI SEDIAAN SABUN CAIR EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava L) DENGAN BASIS MINYAK KELAPA TERHADAP BAKTERI Staphylococcus aureus tohir, fauzha muftia; ahwan, ahwan; Qonitah, Fadilah
Jurnal Farmasi Sains dan Teknologi Vol. 3 No. 01 (2025): Jurnal Farmasi Sains dan Teknologi
Publisher : PC Ikatan Apoteker Indonesia (IAI) Karanganyar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65117/x33p6m60

Abstract

The use of extracts from medicinal plants in the community is used to prevent diseases, maintain body freshness and treat diseases. Guava leaves (Psidium guajava L) contain active compounds such as tannins, triterpenoids, flavonoids, saponins, alkaloids, and essential oils that have antibacterial effects. This study aims to determine the antibacterial activity of liquid soap ethanol extract of guava leaves against Staphylococcus aureus bacteria. The liquid soap formula of guava leaf extract (Psidium guajava L) is made into 4 formulas F0 (0%), F1(5%), F2(10%), and F3(15%). Antibacterial activity is seen from the antibacterial activity test using the diffusion method. Physical testing of guava leaf ethanol extract liquid soap includes organoleptic, pH, foam height, homogeneity, and viscosity. The results of the study showed that the entire formula qualified for good physical properties and could inhibit the growth of Staphylococcus aureus. The results of the antibacterial activity test showed that guava leaf extract soap (Psidium guajava L) had an inhibition in the formula F0 of 0.00±0.00 mm (no antibacterial activity), F1 of 4.60±0.46 mm (weak antibacterial activity), F2 of 5.27±0.06 mm (moderate antibacterial activity), F3 of 5.93±0.32 mm of moderate antibacterial activity) and a positive control of 11.77±1.46 mm (strong antibacterial activity). Based on the results of the study, it was concluded that the liquid soap formula of guava leaf extract (Psidium guajava L) has good physical properties and shows antibacterial activity against Staphylococcus aureus, and does not differ significantly (p<0.05). 
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI MARKISA UNGU (Passiflora edulis Sims) TERHADAP Propionibacterium acnes: ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT OF PURPLE PASSION FRUIT SEEDS (Passiflora edulis Sims) AGAINST Propionibacterium acnes Rifani, Inesta; Ariastuti, Reni; Qonitah, Fadilah
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/3413qz27

Abstract

Inflammation of the hair follicles and sebaceous glands causes acne, a common skin disorder often triggered by bacterial infections such as Propionibacterium acnes. This study aims to determine the antibacterial activity of an ethanolic extract of purple passion fruit seeds against Propionibacterium acnes. The extraction process was carried out by maceration using 96% ethanol. The antibacterial activity of the extract was tested using the disk diffusion method (Kirby-Bauer) at concentrations of 10%, 20%, and 30%, with positive control (clindamycin) and negative control (1% DMSO) for comparison. Antibacterial activity was measured based on the inhibition zone diameter. The data obtained were then statistically analyzed using a one-way ANOVA test with a 95% confidence level. The extract yield was 5.78% and contained chemical compounds such as flavonoids, alkaloids, tannins, saponins, and terpenoids. The antibacterial test results showed inhibition zones for the 10%, 20%, and 30% extract concentrations and the positive control (clindamycin) of (6.45 ± 1.86) mm (moderate activity), (10.38 ± 0.29) mm (strong activity), (12.21 ± 1.21) mm (strong activity), and (17.78 ± 0.55) mm, respectively. Statistically, there was a significant difference in antibacterial activity between the samples (p-value < 0.05). In conclusion, the ethanolic extract of passion fruit seeds possesses antibacterial properties effective against Propionibacterium acnes..   Keywords: antibacterial, seed, Passiflora edulis Sims, Kirby_bauer, acne
Co-Authors -, Ahwan abdul, ahwan Ahwan Ahwan Ahwan Ahwan Ahwan, Ahwan Ariastuti, Reni Azizah, Reyza Nur Dewi, Anita Oktaviana Trisna Dg. Majid, Viranty Elvina erlan Erma Yunita Fitriyatun NurKhotimah Hanafi, Affan Hasna Fadlu Rahma Indriastiningsih, Erna Kharismatul Khasanah Kusuma Wardani, Tiara Maharani, Pratiwi Mistriyani, Mistriyani Nabila, Jihan Namirah, Siti Nurul Jannah Nuzulul Ulmiyah Ramadhan Pratama, Nofran Putra Puji Astutik, Anggit Putri Indah Sayakti Putri, Devi Ananda Rifani, Inesta Risma Sakti Pambudi Rosana, Marilis Sakti Pambudi, Risma Santika, Maria SEPTI WULANDARI Suwardi Suwardi Syamsu Nur, Syamsu tohir, fauzha muftia Triana Hertiani Widagdo, Arisena Yuliyanti, Andini Dwi Zulaika, Laili nur Zulbayu, L.M. Andi Zuriyah, Putri _, Partonowati