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All Journal Pharmacon Jurnal Ilmiah Pangabdhi Cendekia Journal of Pharmacy CERATA Jurnal Ilmu Farmasi Jurnal Pengabdian Harapan Ibu (JPHI) Madaniya Pena : Jurnal Ilmu Pengetahuan dan Teknologi Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Pengabdian kepada Masyarakat JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Sasambo Journal of Pharmacy Khazanah: Jurnal Mahasiswa PENA ABDIMAS : Jurnal Pengabdian Masyarakat Jurnal Pengabdian Harapan Ibu (JPHI) Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Journal of Pharmaceutical (JOP) Jurnal Kesehatan Mahardika Benzena Pharmaceutical Scientific Journal CERATA Jurnal Sains dan Kesehatan Darussalam Advances In Social Humanities Research Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Sains & Kesehatan Darussalam Ulil Albab
Kharismatul Khasanah
Program Studi Farmasi, Fakultas Farmasi, Universitas Pekalongan
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Deteksi Asam Mefenamat pada Jamu Pegel Linu yang beredar di Wilayah Pekalongan Rusmalina, Siska; Khasanah, Kharismatul; Nugroho, Denny Kurniawan
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.10111

Abstract

Jamu Pegel Linu is one of the most popular herbs in Indonesia and oftenly the producers added medicinal chemicals (BKO) so that the resulting therapeutic effect is more effective. One of the BKO added is mefenamic acid. The added content of mefenamic acid can cause harmful side effects such as seizures and can even cause coma. This study aimed to detect the BKO content of mefenamic acid in Jamu Pegel Linu distributed in Pekalongan region. This research was a descriptive study with purposive sampling. The sample used was all Jamu pegel linu that were distributing in Pekalongan region that were included the inclusion and exclusion criteria. The analytical method used is Thin Layer Chromatography (TLC) with a mobile phase in the form of ethyl acetate: methanol: ammonia (80:10:10). Spotting detection was carried out under UV light at λ 254 nm. The results of the spots obtained were compared with a comparison standard. To ensure the results obtained are confirmed using the color reaction method. The results of testing of 27 samples by TLC method obtained there are 3 (three) samples of herbal medicine giving positive results indicated by the similarity of rf values with comparative standards. The results obtained were tested qualitatively with color reagents to strengthen the results.
Pengaruh Intervensi Terhadap Pengetahuan Farmasis Remaja Tentang Swamedikasi Yunita, Erma; Qonitah, Fadilah; Khasanah, Kharismatul; Zulbayu, L.M. Andi; Mistriyani, Mistriyani; Pratama, Nofran Putra; Jannah, Nurul; Sayakti, Putri Indah; Wulandari, Septi; Nur, Syamsu; Hertiani, Triana
Journal of Community Engagement and Empowerment Vol 1, No 1 (2019)
Publisher : Institut Ilmu Kesehatah Bhakti Wiyata Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang: Farmasis remaja memiliki peran dalam pembangunan kesehatan. Salah satu kegiatan yang dilakukan adalah penerapan swamedikasi. Tujuan: Pentingnya peran farmasis remaja dalam swamedikasi mendorong dilakukannya kegiatan pengabdian dengan tema pengenalan peran farmasis remaja dalam swamedikasi. Metode: Peserta diberikan pretest dan selanjutnya diberi intervensi berupa materi umum terkait swamedikasi, diskusi dan praktek swamedikasi bersama tutor. Media yang digunakan berupa materi dalam bentuk power point, modul dan alat peraga. Kegiatan diakhiri dengan melakukan posttest pada peserta yang sama. Hasil: Hasil pretest menunjukan bahwa hanya 14 peserta (20,29%) yang memiliki pengetahuan baik, sedangkan 50 peserta (72,46%) berpengetahuan cukup dan 5 peserta (7,25%) memiliki pengetahuan kurang. Nilai rata-rata hasil pretest adalah 57,10. Setelah diberi intervensi, hasil posttest menunjukan bahwa 66 peserta (95,65%) memiliki pengetahuan baik, sedangkan hanya sejumlah 3 peserta (4,35%) yang masih memiliki pengetahuan cukup. Nilai rata-rata posttes adalah 85,60. Kesimpulan: Adanya peningkatan nilai ini menunjukkan bahwa pemberian intervensi dalam program pengenalan farmasis remaja dalam swamedikasi yang diberikan dapat meningkatkan pengetahuan siswa SMK Pelita Bangsa Yogyakarta tentang swamedikasi. Perlu dilakukan penelitian sejenis dengan jangka waktu antara pretest dengan posttest lebih dari 1 bulan.
Pemanfaatan toga dalam bentuk serbuk instan guna peningkatan imunitas pada masa pandemi di Poncol RT 03 RW 05 Pekalongan Timur Rusmalina, Siska; Ardianingsih, Arum; Khasanah, Kharismatul; Hadi, Nafis Danial; Meilisa, Selvia
Jurnal Pengabdian Harapan Ibu (JPHI) Vol 3 No 2 (2021): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/jphi.v3i2.559

Abstract

Pemberdayaan Kesejahteraan Keluarga (PKK) RT.03 RW. 05 Dukuh Poncol Kelurahan Poncol Kecamatan Pekalongan Timur Kota Pekalongan merupakan mitra PkM yang diusulkan. Anggota mitra PkM ini terdiri dari ibu-ibu rumah tangga yang tidak produktif secara ekonomi. Namun berhasrat kuat menjadi kelompok ekonomi produktif dengan memanfaatkan pekarangan yang mereka miliki guna peningkatan kesehatan dan ekonomi keluarga. Pengusul dengan mitra PkM telah melakukan observasi melalui FGD, dan terumuskan permasalahan mitra. Progam Pengabdian kepada Masyarakat ini dilaksanakan di bulan Juni – September 2021, bertempat di RT.03 RW.05 Dukuh Poncol Pekalongan Timur. Sasaran kegiatan adalah Ibu-Ibu PKK RT.03 RW. 05 Dukuh Poncol Pekalongan Timur. Progam PkM ini secara garis besar Pengurusan Ijin Pelaksanaan Kegiatan PkM, Sosialisasi Kegiatan Kepada Mitra dan Pembentukan Koordinator, Penyuluhan Manfaat TOGA,Pemahaman apakah TOGA itu, Jenis-jenis tanaman TOGA, Penyuluhan manfaat TOGA untuk Kesehatan, Penyuluhan dan Pelatihan Pemanfaatan Hasil TOGA, dan Monitoring dan Evaluasi (monev) disetiap progam yang dilaksanakan. Kegiatan Pengabdian kepada Masyarakat ini sangat memberikan manfaat terutama bagi warga RT.03 RW. 05 Poncol Pekalongan Timur yakni meningkatnya pengetahuan warga terhadap Toga, cara memanfaatkan TOGA guna mengatasi masalah kesehatan, dan pengolahan TOGA menjadi produk bernilai ekonomi. Hal ini dapat dilihat dari nilai postes sasaran yang menunjukkan adanya peningkatan pengetahuan atau pemahaman sasaran mengenai TOGA.
Deteksi Asam Mefenamat pada Jamu Pegel Linu yang beredar di Wilayah Pekalongan Siska Rusmalina; Kharismatul Khasanah; Denny Kurniawan Nugroho
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.10111

Abstract

Jamu Pegel Linu is one of the most popular herbs in Indonesia and oftenly the producers added medicinal chemicals (BKO) so that the resulting therapeutic effect is more effective. One of the BKO added is mefenamic acid. The added content of mefenamic acid can cause harmful side effects such as seizures and can even cause coma. This study aimed to detect the BKO content of mefenamic acid in Jamu Pegel Linu distributed in Pekalongan region. This research was a descriptive study with purposive sampling. The sample used was all Jamu pegel linu that were distributing in Pekalongan region that were included the inclusion and exclusion criteria. The analytical method used is Thin Layer Chromatography (TLC) with a mobile phase in the form of ethyl acetate: methanol: ammonia (80:10:10). Spotting detection was carried out under UV light at λ 254 nm. The results of the spots obtained were compared with a comparison standard. To ensure the results obtained are confirmed using the color reaction method. The results of testing of 27 samples by TLC method obtained there are 3 (three) samples of herbal medicine giving positive results indicated by the similarity of rf values with comparative standards. The results obtained were tested qualitatively with color reagents to strengthen the results.
IDENTIFIKASI BAHAN PENGAWET FORMALIN DAN BORAK PADA BEBERAPA JENIS MAKANAN YANG BEREDAR DI PEKALONGAN Kharimatul Khasanah; Siska Rusmalina
Pena Jurnal Ilmu Pengetahuan Dan Teknologi Vol 33, No 2 (2019): PENA SEPTEMBER 2019
Publisher : LPPM Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/jurnalpena.v33i2.898

Abstract

Formaldehyde and Boris acid are dangerous preservatives which are added to many types of food by irresponsible traders Formaldehyde is used because the price is relatively cheap and it can make food last a long time, while borax can also increase suppleness and give a savory taste. The use of formaldehyde and borax additives violates RI Regulation No. 033 of 2012 concerning prohibited food additives. The danger of continual exposure to formaldehyde and borax can cause respiratory irritation, nausea, vomiting, diarrhea, cell changes / cell death that can lead to cancer and death. The purpose of this study was to determine the presence of formalin in several types of food circulating in the city / district of Pekalongan from 2018 to 2019. The samples used were wet noodles, meatballs, salted fish, tofu, and brains. Formalin testing was carried out qualitatively using Schiff reagents by observing the color changes that occur. And qualitative testing of borax by flame test and turmeric test. The results showed that in 2018 and 2019 the level of use of formalin was high with a percentage above 40% and the use of boric acid around 12.5-13.33% so it could be said to be unfit for consumption and not good for health.
PENERAPAN GREEN CHEMISTRY PADA DETEKSI KANDUNGAN PEWARNA BERBAHAYA (RHODAMIN B) PADA PRODUK KOSMETIK YANG BEREDAR DI WILAYAH PEKALONGAN Kharimatul Khasanah; Siska Rusmalina; Dhea Safira; Eka Ari Setyorini; Nila Amanah
Pena Jurnal Ilmu Pengetahuan Dan Teknologi Vol 36 (2022): EDISI KHUSUS PENELITIAN LPPM UNIKAL
Publisher : LPPM Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/jurnalpena.v36i0.1958

Abstract

Cosmetics play an important role for a woman so that many women do various ways to beautify themselves, including by using cosmetics. In the era of globalization, people's cosmetic needs are increasing, so the circulation of cosmetic products tends to increase. This triggers competition among producers to offer superior products that can attract consumers. This competition is the cause of the emergence of unscrupulous producers to abuse active substances that are prohibited in cosmetics such as rhodamine B dye. its use is prohibited because the impact can be detrimental to the user. The purpose of this study was to determine the Rhodamine B dye in cosmetic preparations in several types of preparations circulating in the Pekalongan Region. In this study, descriptive research method was used, namely qualitative identification of samples in the laboratory using thin layer chromatography to determine the presence of Rhodamine B dye by applying the concept of Green Chemistry. In principle, Green Chemistry is an effort to apply research methods that develop chemical processes and environmentally friendly chemical products. The results of the study stated that from 17 samples, 3 samples were declared positive for containing Rhodamine B in the samples coded BB, LC and ED. The research results obtained can be used as a reference for the public to be more careful and thorough in choosing cosmetics.
PELATIHAN PEMBUATAN PROBIOTIK HERBAL BAGI KELOMPOK PEMBUDIDAYA IKAN Hayati Soeprapto; Heri Ariadi; Kharismatul Khasanah
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 8: Januari 2022
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v1i8.1015

Abstract

The use of probiotics with herbal ingredients is considered to provide many benefits for fish farming activities. The purpose of this community service activity is to educate aquaculturist about the procedures for making and using herbal probiotics for aquaculture activities. The method used in the implementation of this community service activity is counseling and training activities related to the manufacture of herbal probiotics and their application to feed, then mentoring activities are also carried out. This activity was attended by 12 fish farmers in Jeruksari Village, Pekalongan Regency. The results of this community service activity show the potential for aquaculture in Jeruksari Village is quite promising to be developed. In addition, during the service activities, the aquaculturist were also very active in participating in activities starting from the presentation of the manufacture and function of herbal probiotics during the counseling session to when the tutorial on making herbal probiotics was conducted. In addition, participants also feel benefited by the knowledge transfer that they can apply in their daily activities. The conclusion that can be drawn from the implementation of this community service activity is that in general the service activities regarding the training of making herbal probiotics are going very well and in accordance with the target of the program. Participants said that this kind of program activity was considered to provide a lot of knowledge and benefits for them
KOMBINASI EKSTRAK TEMU PUTIH (CURCUMA ZEDOARIA) DAN BAWANG PUTIH (ALLIUM SATIVUM L.) TERHADAP AKTIVITAS SEL LIMFOMA DENGAN METODE MTT ASSAY Istiqari Silma Arifah; Kharismatul Khasanah; Diny Lidy; Herianto Pandapotan
Khazanah: Jurnal Mahasiswa Vol. VII, No. 2, Januari 2015
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol7.iss2.art3

Abstract

Tumor merupakan proses terjadinya pertumbuhan sel yang tidak beraturan dan tak terkontrol (abnormal). Tumor ini bisa bersifat kanker (malignant) atau non-kanker (jinak). Dengan dilakukan penelitan terhadap aktivitas sel lymphoma terhadap kombinasi ekstrak temu putih dan bawang putih menggunakan metode MTT Assay bertujuan untuk menguji keefektifan dari kombinasi ekstrak tersebut terhadap aktifitas sel lymphoma. Bawang putih (Allium sativum) memiliki senyawa organosulfur yang dapat menekanan proliferasi sel dengan menghalangi perkembangan siklus sel tanpa diikuti kerusakan sel disekitarnya. Sedangkan temu putih (Curcuma zedoaria) memiliki mekanisme anti kanker dengan menginduksi apoptosis dari sel kanker itu sendiri tanpa merusak sel lain disekitarnya. Kombinasi ekstrak tersebut diharapkan dapat member efek sinergi dalam penghambatan aktivitas tumor lymphoma. Serbuk simplisia dibuat dalam bentuk ekstrak dengan menggunakan metode maserasi dan menggunakan pelarut etanol 70%. Maserat yang telah diperoleh akan disaring dan diuapkan dengan penguap vakum atau penguap tekanan rendah hingga diperoleh ekstrak kental. Ekstrak kental kemudian diujikan pada sel lymphoma dengan seri dosis 50 : 50 ( 500 : 500 ; 250 : 250 ; 125 : 125 ; 62,5 : 62,5 ; 31,25 : 31,25 ; 15, 625 ; 15, 625 ppm) yang telah dibiakkan pada media komplit di dalam mikroplate dan diberi reagen MTT Assay 0,5%. Hal ini bertujuan untuk mengamati besarnya persen kematian sel (%) dan kristal formazan yang terbentuk. Data hasil pengamatan yang diperoleh, dianalisis dengan menggunakan Elisa reader pada panjang gelombang 550 nm.
EDUKASI DAN EVALUASI TINGKAT PENGETAHUAN WARGA SEKITAR MASJID DI DAERAH PEKALONGAN BARAT MENGENAI PENGGUNAAN HANDSANITIZER GUNA PENCEGAHAN COVID-19 Kharismatul Khasanah; Metha Anung Anindhita; Ekanita Desiani; Siska Rusmalina
PENA ABDIMAS : Jurnal Pengabdian Masyarakat Vol 2, No 1 (2021): Januari 2021
Publisher : LPPM Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (750.164 KB)

Abstract

Corona virus or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that attacks the respiratory system. The disease due to this infection is called COVID-19. Corona virus can cause respiratory system disorders, acute pneumonia, and death. Prevention of coronavirus can be started from ourself. One of the things that can we do is to know the current information about the Covid-19 pandemic on the WHO website and through public health authorities. WHO advises all of us to avoid novel Covid-19 virus infection by maintaining our health and protecting others.One of them is by doing hand washing using a handsanitizer. These handsanitizers are a new habit and need to be done consistently. In order to prevent the maximum transmission, we must use a handsanitizer appropriately. It is intended that the worship process at the mosque can continue and also to prevent the transmission of Covid-19. This method of community service is the manufacture and distribution of handsanitizer and education of the use of a good and correct handsanitizer to the residents around the mosque. The Community Service Activities Program carried out can provide benefits to the community in the knowledge of using Handsanitizer correctly in preventing the transmission of novelcorona virus (Covid-19). Keyword : Covid-19, Handsanitizer, prevention
FORMULASI SEDIAAN TABLET HISAP EKSTRAK DAUN GLODOKAN TIANG DENGAN CMC Na SEBAGAI BAHAN PENGIKAT Metha Anung Anindhita; Kharismatul Khasanah; Sajuri Sajuri; Ardiana Priharwanti; Ivan Sulistyanto
Cendekia Journal of Pharmacy Vol 6, No 2 (2022): Cendekia Journal of Pharmacy
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v6i2.198

Abstract

Tubuh manusia memerlukan antioksidan yang dapat melindungi dari serangan radikal bebas, glodokan tiang (Polyalthia longifolia (Sonn.)Thwaites ) merupakan salahsatu tanaman yang berpotensi sebagai antioksidan. Penggunaan daun glodokan tiang secara langsung dinilai kurang praktis sehingga perlu diformulasi dalam bentuk sediaan tablet hisap karena lebih praktis dan mudah dalam penggunaan. Tablet hisap harus cukup keras, sehingga diperlukan bahan pengikat. Penggunaan natrium karboksimetilselulosa (CMC-Na) sebagai bahan pengikat diharapkan mampu memberikan kualitas fisik yang baik.Penelitian ini bertujuan untuk mengetahui CMC-Na sebagai bahan pengikat terhadap sifat fisik sediaan tablet hisap ekstrak daun glodokan tiang. Metode yang digunakan dalam penelitian ini adalah eksperimental dengan membandingkan kadar CMC-Na pada tiga formula yaitu 2% (FI), 3%(FII) dan 4%(FIII). Ketiga formula diuji sifat fisik meliputi organoleptis, keseragaman bobot, keseragaman ukuran, kekerasan, kerapuhan, uji waktu hancur dan uji kesukaan responden untuk menentukan perbedaan dan menentukan formula terbaik. Data organoleptis, kerapuhan dan tanggap rasa dianalisis secara deskriptif, sementara data keseragaman bobot, keseragaman ukuran, kekerasan dan waktu hancur dianalisis secara statistik menggunakan uji One Way Anova dengan taraf kepercayaan 95%, jika nilai signifikansi 0,05 maka dilanjutkan dengan uji post hoc untuk mengetahui adanya perbedaan signifikan untuk tiap formula. Hasil penelitian menunjukkan penggunaan variasi konsentrasi  CMC-Na 2%, 3%, dan 4% pada formula tablet hisap ekstrak daun glodokan tiang berpengaruh terhadap kekerasan, kerapuhan, waktu hancur dan kesukaan responden terhadap  sediaan tablet hisap ekstrak daun glodokan tiang . Formula terbaik tablet hisap ekstrak daun glodokan tiang adalah formula II dengan konsentrasi CMC-Na sebesar 3% yang telah memenuhi nilai kekerasan, kerapuhan dan waktu hancur yang baik.
Co-Authors Adriyana, Rika Adriyana, Rika Aji Cokro Dewanto Alfiana Nur Hidayah Annisa Syafira Annisatul Farokhah Ardiana Priharwanti Ari Muhardono Arum Ardianingsih Danang Satrio Denny Kurniawan Nugroho Dewanti Queen Agustin Dhea Safira Didha Putri Citradika Diny Lidy Dwiki Abdul Mutholi Eka Ari Setyorini Eka Pangestika Ekanita Desiani Elvina Yuniarti Prasetya Erma Yunita Fadilah Qonitah Hadi, Nafis Danial Hayati Soeprapto Hayati Soeprapto Heri Ariadi Heri Ariadi Herianto Pandapotan Isrofah Istiqari Silma Arifah Ivan Sulistyanto Khafid Mahbub Labibah Alawiyah Lu'luul Mahmudah Mahfur, Mahfur Maruf Islammudin Meilisa, Selvia Metha Anung Anindhita Mistriyani, Mistriyani Nafis Danial Hadi Nanda Agung Nila Amanah Nor Rizka Nugroho, Denny Kurniawan Nurul Jannah Pratama, Nofran Putra Puji Wijayanti Putri Indah Sayakti Rika Adriyana Risa Mega Legina Safira Galuh Chandra Sajuri, Sajuri Satrio, Danang Selvia Meilisa SEPTI WULANDARI Shella Sya'bana, Nur Siska Rusmalina Syamsu Nur, Syamsu Triana Hertiani Vera Yunita Wafa Khanza Widyasari, Diah Ayu Yuli Kurniasari Zulbayu, L.M. Andi