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All Journal JOPS (Journal Of Pharmacy and Science) Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Penelitian Farmasi dan Herbal JUKESHUM: Jurnal Pengabdian Masyarakat FORTE JOURNAL International Journal of Health and Pharmaceutical (IJHP) Journal of Pharmaceutical and Sciences.
Robiatun Rambe
Department Of Pharmacy, Universitas Haji Sumatera Utara, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL TUMBUHAN AKAR BALSEM (Polygala paniculata L.) DENGAN METODE DPPH (2,2 diphenyl-1-picrylhydrazyl) Aswan Pangondian; Robiatun Rambe; Nadya Rohma Ritonga; Saddam Husein; Athaillah Athaillah; Nur Aini Khairunnisa; Ovalina Sylvia Br. Ginting; Putra Chandra
FORTE JOURNAL Vol 5 No 1 (2025): Edisi Januari 2025
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v5i1.1249

Abstract

Tumbuhan akar balsem (Polygala paniculata L.) memiliki kandungan kimia seperti alkaloid, flavonid, tanin, saponin dan steroid . Berfungsi sebagai antioksidan yang dapat menangkal radikal bebas sehingga membantu memperlambat proses penuaan dini, menambah kekebalan tubuh terhadapa berbagai penyakit. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ekstrak akar balsem (Polygala paniculata L.) Metode yang digunakan dalam penelitian ini adalah eksperimental meliputi tahapan Penyiapan sampel, pembuatan simplisia, pembuatan ekstrak, uji karakterisasi simplisia, uji skrining fitokimia, dan Uji aktivitas antioksidan menggunakan metode peredaman radikal bebas DPPH. Berdasarkan hasil penelitian diperoleh hasil ekstrak etanol menghasilkan % rendemen sebesar 15,8%. Dari hasil pengukuran aktivitas antioksidan diperoleh nilai IC50 ekstrak etanol akar balsem (Polygala paniculata L.) sebesar 6,92 ppm dan Vitamin C sebesar 1,38 ppm.Kesimpulan penelitian ini bahwa Aktivitas antioksidan dari ekstrak etanol akar balsem (Polygala paniculata L.) termasuk kategori sangat kuat.
Phytochemical Screening And Antioxidant Activity Testing Of Porang (Amorphophallus Muelleri Blume) Leaf Ethanol Extract From Kuta Buluh Region, North Sumatera Ainil Fithri Pulungan; Ridwanto Ridwanto; Gabena Indrayani Dalimunthe; Zulmai Rani; Rahma Dona; Ricky Andi Syahputra; Robiatun Rambe
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.501 KB) | DOI: 10.51601/ijhp.v3i1.141

Abstract

Porang (Amorphallus muelleri Blume) is one type of tuber plant that has the potential to be developed in Indonesia. Porang plants have been reported to contain chemical compounds that have antioxidant activity. This research was conducted on the leaves of the porang plant with the aim of knowing the antioxidant activity, characterization, and phytochemical profile of the compounds contained therein. Compound identification and characterization were performed using standard methods, and antioxidant activity was determined using the DPPH (1,1- Diphenyl-2-picrylhydrazyl ) method. The results of the identification of chemical compounds showed that the ethanol extract of porang leaves contained chemical compounds of alkaloids, flavonoids, tannins, saponins, and steroids. The results of the examination of the simplicia characterization of porang leaves included the soluble ethanol content of 33.93%, the water soluble extract content of 17.3%, the ash content of 5.58%, the acid insoluble ash content of 0.235% and the water content of 8%. From the results of the simplicia characterization, it shows that the results meet the specified requirements. The results showed that the ethanol extract of porang leaves had antioxidant activity with an IC50 value of 93.04 µg/mL, which in this case is included in the category of strong antioxidant activity. Meanwhile, as a comparison, Vitamin C was used, which has an IC50 value of µg/mL, which is included in the category of very strong antioxidant activity.
Co-Authors zulfikri zulfikri Anisa Safira Sitorus ASWAN PANGONDIAN Athaillah, Athaillah Aulia Fitri Chindy Umaya Depi Yasinta Dwi Kumala Sari Erma Susanti Ernawaty Ginting Evi Depiana Gultom Evi Depiana Gultom Evi Depiana Gultom Evi Depiana Gultom Fahra Nisa Fauziah Erna Witular Panggabean Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Hanafis Sastra Winata Herti Ayu N Zebua Kadriyani Jambak Lilik Septiana Lintang Kautsar Mita Yusmira Lestari Caniago Musyirna Rahmah Nst Nadya Rohma Ritonga Nur Ain Thomas Nur Aini Khairunnisa Nurhayati Marpaung Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Pinte Mahara HS Putra Chandra Ratih Paramitha Ratih Paramitha Ricky Andi Syahputra Ridwanto Ridwanto Riezky Chairunnisa Sabrina Aufari Harahap Saddam Husein Selvina Selvina Shela Diana Yulanda Yulanda Yuli Haryani Yuliatil Adawiyah Harahap Ziza Putri Aisyia Fauzi Zulfikri Zulfikri Zulmai Rani