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All Journal CHEMICA Jurnal Teknik Kimia Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biologi Tropis Jurnal PAJAR (Pendidikan dan Pengajaran) Biosaintifika: Journal of Biology & Biology Education BIOSFER : Jurnal Biologi dan Pendidikan Biologi Jurnal Pendidikan dan Konseling Bubungan Tinggi: Jurnal Pengabdian Masyarakat Optika : Jurnal Pendidikan Fisika Mitra Mahajana: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Mandiri Biocaster : Jurnal Kajian Biologi
Wae, Veronika P. S. M.
Universitas Flores, Ende, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Energy Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Physics Public Health Social Sciences Other

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Adaptasi Sel terhadap Perubahan Lingkungan Osmotik Ekaputra, Paulus Rudirudolof; Sumira, Sumira; Doi, Yohana Fransiska; Ohaq, Emanuel; Wae, Veronika P. Sinta Mbia
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 1 (2026): January
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i1.873

Abstract

This study aims to examine the mechanism of cell adaptation to hypertonic conditions through osmoregulation processes in various types of cells and organisms. The method used is a systematic literature review of 30 national and international journal articles sourced from Google Scholar and ScienceDirect databases. Articles were selected based on inclusion criteria that include topic suitability, availability of osmotic experimental data, and relevance to cellular responses. The results of the study indicate that cells adapt through the accumulation of compatible osmolytes such as proline, glycine betaine, and sorbitol to maintain intracellular water and ion balance. This response was observed in various objects, including Rhoeo discolor cells that showed optimal adaptation to 0.26 M sucrose with a decrease in plasmolysis from 85% to 36%, and Inpari rice seeds with an increase in drought tolerance of up to 50% through proline accumulation. Active osmoregulation was also found in frog erythrocytes, Lactobacillus plantarum, tiger prawns (543-610 mOsm/L), and tilapia which recorded an 80% survival rate at graded salinities. In general, increased osmoregulatory capacity significantly reduced cell damage from hypertonic stress, although the magnitude of the response varied among organisms. These findings have important implications for the development of rainfed agriculture, brackish water aquaculture management, and the selection of genotypes resistant to extreme climate change.
A Review of Structural and Functional Differences Between Plant and Animal Cell Organell Nisa, Fadhila Chairul; Bupu, Karolina; Wele, Mery Kristina; Falo, Yohanes Baptis Dela; Wae, Veronika P. Sinta Mbia
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.10953

Abstract

Understanding the dynamic organization of organelles is fundamental to biology, yet traditional perspectives often overlook the complex inter-organellar communication that defines cellular physiology. This systematic review synthesizes thirty peer-reviewed articles (2015–2025) to bridge the knowledge gap between static organelle morphology and modern functional dynamics in plant and animal cells. By employing a systematic literature review (SLR) approach with thematic synthesis, this study identifies that while core organelles are conserved, specialized structures such as chloroplasts and large vacuoles in plants versus centrioles and lysosomes in animals exhibit distinct evolutionary adaptations in redox balance and quality control mechanisms. The analysis further reveals a universal reliance on inter-organellar contact sites and autophagy pathways, suggesting that cellular health is maintained through a highly integrated "organelle ecosystem" rather than isolated units. These findings offer critical insights for advancing cell biology education and provide a theoretical framework for future research in metabolic engineering and stress adaptation in tropical biological systems.
Impacts of Microplastics on the Cells of Aquatic Organisms Keke, Adolfin; Naring, Theresia; Itu, Maria Dolfiana; Wae, Veronika P. Sinta Mbia
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.10986

Abstract

Microplastics (<5mm) are currently one of the most concerning contaminants in aquatic environments, especially in coastal areas of Indonesia. This literature review aims to identify the types, sources, and abundance levels of microplastics, as well as their potential impacts on aquatic organisms and implications for human health. Microplastics were found at concentrations of approximately 38,000 particles per kilogram of sediment in Indonesian waters and more than 1,500 particles per individual in aquatic animals. Microplastic pollution has been shown to accumulate in the digestive systems of organisms and can translocate to tissues, which can then enter the human food chain. Health impacts that have been identified include the risk of chronic inflammation, digestive system disorders, liver damage, and an increased risk of cancer. Overall, this literature review shows that microplastic pollution in aquatic organisms in Indonesia is at a very worrying level and requires decisive action through reducing the use of plastic materials, improving waste processing, and continuous monitoring. These conditions can harm all aquatic organisms, leading to digestive disorders and even death.
Pengaruh Radiasi terhadap Struktur dan Fungsi Sel Lado, Tiara Novianti Dadi; Bhoki, Lidia Delvina; Rithi, Santiana E.; Soba, Tersius; Wae, Veronika P. Sinta Mbia
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 2 (2026): April (In Progress)
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i2.993

Abstract

Ionizing and non-ionizing radiation are widely used in health, industry, scientific research, and communication technology, but their use also has the potential to pose biological risks to humans. Therefore, a comprehensive understanding of the mechanisms of radiation interaction with biological tissues and their health implications is crucial. This study aims to systematically examine the biological effects of ionizing and non-ionizing radiation on human health, as well as the safety principles applied in their use. The research method used is a literature review by examining scientific articles, reports from international institutions, and relevant publications that discuss radiation exposure, biological impacts, and aspects of radiation protection. The results of the study indicate that ionizing radiation, such as X-rays and gamma rays, has the ability to ionize atoms and molecules, thus potentially causing DNA damage that can trigger deterministic and stochastic effects, including an increased risk of cancer. Although radiation doses in medical diagnostic procedures are generally below the hazardous threshold, the application of radiation protection principles in the form of justification, optimization, and dose limitation remains a key factor in ensuring the safety of patients and healthcare workers. While non-ionizing radiation from telecommunications devices does not cause ionization, at high exposure levels it can cause thermal effects on biological tissue, although most epidemiological studies have not shown a consistent link with an increased risk of cancer. Exposure to cosmic radiation during commercial flights and at high altitudes has the potential to cause dose accumulation, which requires special attention. The conclusion of this study emphasizes that radiation use must be accompanied by adequate scientific understanding, long-term risk evaluation, and the implementation of strict safety policies to ensure that the benefits of radiation use outweigh the risks.
Autofagi : Mekanisme Pemeliharaan Diri Sel dalam Kondisi Stres Lejo, Kanisia Petra Seto; Kanggo, Jihan Pramitha; Wea, Maria Ventiana; Zaki, Alfa; Wae, Veronika P. Sinta Mbia
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 2 (2026): April (In Progress)
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i2.995

Abstract

Autophagy is a cellular mechanism in the form of degradation and recycling of intracellular components that plays an important role in maintaining cell homeostasis, especially when cells are under stress conditions such as nutritional limitations, oxidative stress, organelle damage, or pathogen attacks. Through this process, cells are able to survive by eliminating damaged or dysfunctional structures, while simultaneously reusing the degradation products as a source of energy and building blocks for new molecules. This study aims to examine the mechanism of autophagy, the molecular regulations involved, and its role in the response to various forms of cellular stress using a literature review method. Reference sources in this study come from relevant scientific articles and are accessed through PubMed, Scopus, and Google Scholar databases with a publication year range of 2015-2024. Articles are selected based on the main inclusion criteria, namely discussions on the molecular pathway of autophagy, the process of autophagosome formation, and the role of lysosomes in cellular degradation mechanisms. The study results indicate that autophagy is an essential adaptive mechanism primarily controlled by the mTOR and AMPK pathways in response to cellular stress. Adaptive autophagy plays a crucial role in maintaining cell stability and survival, while autophagy dysfunction or uncontrolled activation is pathological and contributes to the development of various diseases, making autophagy a strategic therapeutic target. Furthermore, disruption of the autophagy process is known to be closely associated with the development of various degenerative and metabolic diseases, making autophagy a potential target in the development of biomedical therapeutic strategies.
Co-Authors Abbas, Azizah Amalia Ainun Jariah Ainun Jariyah Ainun Jariyah Ainun Jariyah Ainun Jariyah Astria, Astria Babo, Anjelina Larici Bara, Filomena Enjelina Bhaghi, Emaliano Jonsimus Lea Bhoki, Lidia Delvina Bupu, Karolina Bupu, Yuliana Carvallo, Ludovicus Df, Denita Doi, Yohana Fransiska Ekaputra, Paulus Rudirudolof Falo, Yohanes Baptis Dela Fatima, Noviana Deam Gaga, Florentinus Gago, Jumilah Hayon, Melkior Bala Intan Permatasari Itu, Maria Dolfiana Kaleka, Melkyanus B.U. Kanggo, Jihan Pramitha Keke, Adolfin Lado, Tiara Novianti Dadi Laurensia Due Lejo, Kanisia Petra Seto Leta, Yohanes Mari Ba'i Ludovicus Carvallo Maimunah H. Daud Mala, Benedikta Odaliva Mala, Nurfadila Maria Diana Kemba Maria Fatima Mei Maria Waldetrudis Lidi Melania Priska Nadrahwati Binti Muthalib Naring, Theresia Natalia Peni Ndang, Yustika Elviani Nena, Anastasia Modesta Ngama, Yulita Erlina Ngange, Bonefasia Gabriela Noni Nisa, Fadhila Chairul Nona, Hadijah Ohaq, Emanuel Oka, Elisabet Owa, Maria Fransiska Owa, Maria Prima Papa, Florentina Christiani Rahmadani, Lutfitri Rithi, Santiana E. Sado, Thomas Wayan Pao Sani, Stefan Anselmus Lamen Sepe, Fransiska Petronela Soba, Tersius Sumira, Sumira Surideo, Genoveva Angela Wea, Maria Ventiana Wele, Mery Kristina Yofran, Yuliani Putri Yosephina Payu Wao Yuliana Yenita Mete Yuliana Yenita Mete Yulius Saprianus Dala Ngapa Zaki, Alfa