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Pengaruh Radiasi terhadap Struktur dan Fungsi Sel Tiara Novianti Dadi Lado; Lidia Delvina Bhoki; Santiana E. Rithi; Tersius Soba; Veronika P. Sinta Mbia Wae
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 2 (2026): April
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i2.993

Abstract

Ionizing and non-ionizing radiation are widely used in health, industry, scientific research, and communication technology, but their use also has the potential to pose biological risks to humans. Therefore, a comprehensive understanding of the mechanisms of radiation interaction with biological tissues and their health implications is crucial. This study aims to systematically examine the biological effects of ionizing and non-ionizing radiation on human health, as well as the safety principles applied in their use. The research method used is a literature review by examining scientific articles, reports from international institutions, and relevant publications that discuss radiation exposure, biological impacts, and aspects of radiation protection. The results of the study indicate that ionizing radiation, such as X-rays and gamma rays, has the ability to ionize atoms and molecules, thus potentially causing DNA damage that can trigger deterministic and stochastic effects, including an increased risk of cancer. Although radiation doses in medical diagnostic procedures are generally below the hazardous threshold, the application of radiation protection principles in the form of justification, optimization, and dose limitation remains a key factor in ensuring the safety of patients and healthcare workers. While non-ionizing radiation from telecommunications devices does not cause ionization, at high exposure levels it can cause thermal effects on biological tissue, although most epidemiological studies have not shown a consistent link with an increased risk of cancer. Exposure to cosmic radiation during commercial flights and at high altitudes has the potential to cause dose accumulation, which requires special attention. The conclusion of this study emphasizes that radiation use must be accompanied by adequate scientific understanding, long-term risk evaluation, and the implementation of strict safety policies to ensure that the benefits of radiation use outweigh the risks.
Autofagi : Mekanisme Pemeliharaan Diri Sel dalam Kondisi Stres Kanisia Petra Seto Lejo; Jihan Pramitha Kanggo; Maria Ventiana Wea; Alfa Zaki; Veronika P. Sinta Mbia Wae
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 2 (2026): April
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i2.995

Abstract

Autophagy is a cellular mechanism in the form of degradation and recycling of intracellular components that plays an important role in maintaining cell homeostasis, especially when cells are under stress conditions such as nutritional limitations, oxidative stress, organelle damage, or pathogen attacks. Through this process, cells are able to survive by eliminating damaged or dysfunctional structures, while simultaneously reusing the degradation products as a source of energy and building blocks for new molecules. This study aims to examine the mechanism of autophagy, the molecular regulations involved, and its role in the response to various forms of cellular stress using a literature review method. Reference sources in this study come from relevant scientific articles and are accessed through PubMed, Scopus, and Google Scholar databases with a publication year range of 2015-2024. Articles are selected based on the main inclusion criteria, namely discussions on the molecular pathway of autophagy, the process of autophagosome formation, and the role of lysosomes in cellular degradation mechanisms. The study results indicate that autophagy is an essential adaptive mechanism primarily controlled by the mTOR and AMPK pathways in response to cellular stress. Adaptive autophagy plays a crucial role in maintaining cell stability and survival, while autophagy dysfunction or uncontrolled activation is pathological and contributes to the development of various diseases, making autophagy a strategic therapeutic target. Furthermore, disruption of the autophagy process is known to be closely associated with the development of various degenerative and metabolic diseases, making autophagy a potential target in the development of biomedical therapeutic strategies.
A Review of Structural and Functional Differences Between Plant and Animal Cell Organell Fadhila Chairul Nisa; Karolina Bupu; Mery Kristina Wele; Yohanes Baptis Dela Falo; Veronika P. Sinta Mbia Wae
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.10953

Abstract

Understanding the dynamic organization of organelles is fundamental to biology, yet traditional perspectives often overlook the complex inter-organellar communication that defines cellular physiology. This systematic review synthesizes thirty peer-reviewed articles (2015–2025) to bridge the knowledge gap between static organelle morphology and modern functional dynamics in plant and animal cells. By employing a systematic literature review (SLR) approach with thematic synthesis, this study identifies that while core organelles are conserved, specialized structures such as chloroplasts and large vacuoles in plants versus centrioles and lysosomes in animals exhibit distinct evolutionary adaptations in redox balance and quality control mechanisms. The analysis further reveals a universal reliance on inter-organellar contact sites and autophagy pathways, suggesting that cellular health is maintained through a highly integrated "organelle ecosystem" rather than isolated units. These findings offer critical insights for advancing cell biology education and provide a theoretical framework for future research in metabolic engineering and stress adaptation in tropical biological systems.
Mechanisms of Substance Transport Across the Cell Membrane: Diffusion, Osmosis, and Active Transport Azizah Amalia Abbas; Lutfitri Rahmadani; Fransiska Petronela Sepe; Yohanes Mari Ba'i Leta; Veronika P. Sinta Mbia Wae
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.10979

Abstract

The cell membrane is a semipermeable structure that regulates substance exchange between intracellular and extracellular environments, maintains cellular homeostasis, and supports metabolic processes, yet the fundamental mechanisms of diffusion, osmosis, and active transport are still frequently misunderstood in both theoretical and educational contexts. This study aims to comprehensively review substance transport mechanisms across the cell membrane and their relevance to biology education and contemporary cellular research. This research employed a narrative literature review, analyzing scientific books and peer-reviewed journal articles published within the last five to ten years, selected from databases such as Google Scholar, PubMed, and MDPI based on topic relevance. The results indicate that diffusion facilitates molecular movement along concentration gradients either directly or through transport proteins; osmosis regulates water balance through semipermeable membranes mediated by aquaporins; and active transport enables the movement of ions and molecules against concentration gradients through ATP-dependent pumps, secondary transporters, ABC transporters, and V-ATPase. These mechanisms are interconnected and influenced by membrane composition, molecular characteristics, and transporter–substrate interactions. This review highlights the importance of an integrative understanding of membrane transport processes to strengthen conceptual learning in biology education and to support advancements in cellular and biomedical research.
Impacts of Microplastics on the Cells of Aquatic Organisms Adolfin Keke; Theresia Naring; Maria Dolfiana Itu; Veronika P. Sinta Mbia Wae
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.10986

Abstract

Microplastics (<5mm) are currently one of the most concerning contaminants in aquatic environments, especially in coastal areas of Indonesia. This literature review aims to identify the types, sources, and abundance levels of microplastics, as well as their potential impacts on aquatic organisms and implications for human health. Microplastics were found at concentrations of approximately 38,000 particles per kilogram of sediment in Indonesian waters and more than 1,500 particles per individual in aquatic animals. Microplastic pollution has been shown to accumulate in the digestive systems of organisms and can translocate to tissues, which can then enter the human food chain. Health impacts that have been identified include the risk of chronic inflammation, digestive system disorders, liver damage, and an increased risk of cancer. Overall, this literature review shows that microplastic pollution in aquatic organisms in Indonesia is at a very worrying level and requires decisive action through reducing the use of plastic materials, improving waste processing, and continuous monitoring. These conditions can harm all aquatic organisms, leading to digestive disorders and even death.
Tradisi Reba dan Konservasi Uwi (Dioscorea esculenta): Kajian Etnobotani Masyarakat Adat Desa Binawali Kabupaten Ngada Veronika P. Sinta Mbia Wae; Anastasia Modesta Nena; Elisabet Oka; Genoveva Angela Surideo
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.435

Abstract

This study focuses on the Reba tradition and the conservation of yam (Dioscorea esculenta) in Binawali Village, Ngada Regency, through an ethnobotanical approach. The Reba tradition is an annual harvest ritual in which the Ngada ethnic community honors yam as a symbol of life, prosperity, and ancestral heritage. Yam is considered the "bread of life" and their main staple food long before rice and corn were known. Despite having high historical and spiritual value and being easy to cultivate, the utilization of yam is still low, due to the lack of interest of the younger generation and the suboptimal economic utilization which threatens its sustainability as a local agrobiodiversity. This study aims to describe the symbolic meaning of yam in the Reba tradition and examine how the tradition contributes to local and sustainable yam conservation. This study uses a qualitative method with an ethnographic approach, through participant observation, interviews, and documentation of traditional elders, village heads, farmers, and community members for data collection. The results show that the Reba tradition not only functions as an expression of spiritual culture, but also as a mechanism for in situ conservation of yam through customary regulations, management of inherited land, and transmission of local knowledge between generations. This finding emphasizes the importance of strengthening customary institutions as a pillar in community-based agrobiodiversity conservation.
Potensi Tabha Lame sebagai Pangan Fungsional Tradisional untuk Mendukung Laktasi: Kajian Etnobotani di Suku Ua Kabupaten Nagekeo Veronika P. Sinta Mbia Wae; Anjelina Larici Babo; Maria Fransiska Owa; Yuliana Bupu; Bonefasia Gabriela Noni Ngange; Maria Prima Owa
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.515

Abstract

Tabha Lame is a traditional food of the Ua Tribe in Nagekeo Regency which has been traditionally believed to increase breast milk production. However, this belief has never been scientifically studied and systematically documented, especially regarding its nutritional function and ethnobotanical value. This study aims to identify the composition of ingredients, processing, and nutritional potential of Tabha Lame as a locally based functional food. This study was conducted using a qualitative descriptive approach through interviews and field documentation methods with traditional leaders and women who possess traditional knowledge. The results show that Tabha Lame is made from local ingredients, such as: jali (Coix lacryma-jobi), moringa leaves (Moringa oleifera), peanuts (Arachis hypogaea), and coconut milk cooked using the Dhedhu Zaka technique. The content of phytoestrogens, iron, vegetable protein, vitamin A, and unsaturated fatty acids in these ingredients contribute to supporting the lactation process. The slow cooking process maintains micronutrients, while the symbolic presentation demonstrates the integration between nutrition and culture. The conclusion of this study confirms that Tabha Lame is a locally based functional food with potential for development in community-based nutritional interventions for breastfeeding mothers and the preservation of traditional knowledge.
Kajian Etnobotani dalam Makanan Tradisional Wa’ai Zamu sebagai Bentuk Warisan Budaya Masyarakat Ende Veronika P. Sinta Mbia Wae; Hadijah Nona; Intan Permatasari; Florentinus Gaga; Thomas Wayan Pao Sado
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.533

Abstract

This research is an ethnobotanical study of the traditional food Wa'ai Zamu, a form of cultural heritage of the Ende people, East Nusa Tenggara. The objective was to document local knowledge regarding the use of plants in making Wa'ai Zamu and the cultural values it embodies. The study employed a qualitative approach with ethnographic methods. Data were obtained through in-depth interviews with 10 key informants selected purposively, consisting of traditional leaders, women traditional food processors, and local cultural experts. Triangulation techniques were used through participant observation and literature review to strengthen the validity of the data. The results indicate that Wa'ai Zamu uses various types of local plants with nutritional value and symbolic functions in traditional rituals. Information regarding nutritional content comes from informants and is partially supported by previous literature references. This study demonstrates that traditional foods serve not only as daily consumption but also represent the identity and cultural continuity of the Ende people. Documenting this knowledge is crucial for preserving intangible cultural heritage, which is vulnerable to modernization.
Kajian Etnosains Pembuatan Makanan Tradisional Lomak Daerah Manggarai Veronika P. Sinta Mbia Wae; Noviana Deam Fatima; Yustika Elviani Ndang
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 4 (2025): October
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i4.624

Abstract

This study aims to examine the ethnoscientific values contained in the process of making traditional Lomak food from the Manggarai area, East Nusa Tenggara. Lomak is one of the culinary heritage that not only has a distinctive taste, but also reflects the local knowledge of the Manggarai people, starting from the selection of ingredients, processing techniques, to food preservation efforts. This study uses a qualitative approach with data collection techniques in the form of observation, in-depth interviews, and documentation studies. The results of the study show that the process of making Lomak contains scientific principles, such as natural fermentation techniques, sustainable use of local ingredients, and traditional knowledge about sanitation and food conservation. This ethnoscience study is expected to be a source of contextual learning in science education while contributing to the preservation of local culture. The novelty of this research lies in the application of food innovation that combines aspects of business management, marketing strategy, and cultural preservation, so that it has the potential to increase the income of Lomak artisans in the Manggarai area.
Penerapan Metode Demonstrasi Uwi Kaju Kedho untuk Meningkatkan Minat Belajar Peserta Didik SMA Karitas Watuneso Filomena Enjelina Bara; Maria Waldetrudis Lidi; Veronika P. Sinta Mbia Wae
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 4 (2025): October
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i4.657

Abstract

This study aims to assess the effect of the application of the local food-based demonstration method of Uwi Kaju Kedho on the learning interest of students at SMA Karitas Watuneso. The type of research used is quasi-experimental. The design used in this study is a nonequivalent control group. The bound variable in this study is the students' learning interest, while the free variable is the demonstration method based on local food uwi kaju kedho. The population in this study is 123 students in class X, and the research sample is 48 people obtained by purposive sampling technique. The data obtained from the research sample was in the form of a questionnaire. Data analysis was carried out by t-test using the help of SPSS 25 for windows. The results of the study show that the application of local food-based demonstration methods has an effect on the learning interest of students at Karitas Watuneso High School. This can be seen from the results of the study interest questionnaire and observation. The average questionnaire score was 76.10 and the average observation score was 100. The results of the t-test supported the difference in learning interest between the control and experimental groups.