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Formulasi dan Evaluasi Krim Ekstrak Jamur Sawit (Volvariella sp) sebagai Tabir Surya dengan Variasi Konsentrasi Basis Lemak Tengkawang dan Lemak Cokelat Prehatin, Chrisbaningrum; Butarbutar, Maria Elvina Tresia; Sianturi, Sister; Fernandes, Andrian
Majalah Farmasetika Vol 10, No 1 (2025)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v10i1.60520

Abstract

Jamur sawit merupakan bahan alam yang mengandung senyawa antioksidan sangat kuat, yaitu 19,14 bpj, sehingga memiliki potensi sebagai tabir surya. Oleh sebab itu, penelitian ini bertujuan untuk menganalisis aktivitas ekstrak jamur sawit sebagai tabir surya dengan menentukan nilai SPF yang diformulasikan menjadi sediaan krim dengan variasi konsentrasi lemak tengkawang dan lemak cokelat. Metode spektrofotometri UV-Vis digunakan untuk menentukan nilai SPF krim ekstrak jamur sawit. Diuji nilai SPF 7 formula dan diperoleh 3 formula terbaik, yaitu F1 (1,9305), F5 (1,6487), dan F7 (1,7906) untuk selanjutnya dilakukan evaluasi mutu fisik. Pada uji pH, F1, F5, dan F7 memenuhi persyaratan pH kulit, yaitu 4,5-6,5, dasil statistik pH diperoleh p>0,05 menunjukan tidak terdapat perbedaan pada variasi konsentrasi terhadap nilai pH. Pada uji viskositas F1, F5, dan F7 memenuhi persyaratan sediaan krim, yaitu 2.000-50.000 cPs. Pada uji daya sebar F1, F5, dan F7 tidak memenuhi persyaratan sediaan krim, yaitu 5-7 cm. Pada uji daya lekat tidak memenuhi persyaratan waktu daya lekat krim, yaitu <4 detik. Hasil viskositas diperoleh adanya perbedaan pada F1, F5, dan F7 dengan nilai p<0,05. Nilai signifikansi tersebut dapat diartikan adanya pengaruh variasi konsentrasi basis terhadap nilai viskositas.
Antibacterial Activity of Gaharu (Aquilaria malaccensis Lamk) Against the Bacteria Streptococcus pyogenes Elianto, Nopriani; Sianturi, Sister; Saharuddin, Tria Saputra
CELEBES Agricultural Vol. 5 No. 2 (2025): CELEBES Agricultural
Publisher : Faculty of Agriculture, Tompotika Luwuk University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52045/jca.v5i2.888

Abstract

Streptococcus pyogenes is a bacterium that causes throat and skin infections.  Diseases caused by Streptococcus pyogenes bacteria can typically be treated with antibiotics. This study aims to determine the antibacterial activity of the ethanol extract of gaharu leaves (Aquilaria malaccensis Lamk) against the development of Streptococcus pyogenes bacteria using the disc diffusion method. The positive control used the antibiotic clindamycin, and the negative control used 1% DMSO. Observations were made by measuring the inhibition zone formed around the paper disc. The average diameter of the inhibition zone formed included a 10% concentration of 9.8 mm, a 15% concentration of 10.08 mm, a 20% concentration of 11.54 mm, and for the positive control, antibiotic clindamycin, it was 29.92 mm in the very strong category. In contrast, the negative control, 1% DMSO, did not form an inhibition zone. The One Way Anova data analysis test using the SPSS IBM version 26 program obtained results (p>0.05), meaning that there were significant antibacterial and differences in the diameter of the inhibition zone of the ethanol extract of gaharu leaves in each treatment.
Antihypercholesterolemic Activity of Tahongai Leaf infusion (Kleinsovia hospita L.) In Mice (Mus musculus L.) Sianturi, Sister; Sinaga, Clara Ritawany; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.233-238

Abstract

Tahongai (Kleinhovia hospita L.) is an indigenous plant of East Kalimantan known for its health benefits, including antibacterial, anti-inflammatory, antioxidant, anticancer, and antidiabetic properties. This study evaluates the antihypercholesterolemic activity of Tahongai leaf infusion in hypercholesterolemic mice (Mus musculus L.), induced by egg yolk. The test groups included a positive control (simvastatin), a negative control (distilled water), and three treatment groups with Tahongai leaf infusion at concentrations of 15%, 30%, and 60%. The results indicated that the highest reduction in cholesterol levels was observed in the P1 group (15% infusion) with an average decrease of 30.84%, followed by P2 (30% infusion) at 24.79%, and P3 (60% infusion) at 9.31%. The positive control group showed an average reduction of 8.64%. Statistical analysis using One-Way ANOVA revealed a significant difference (p<0.05) in cholesterol level reduction among the treatment groups.
Edukasi Ecopreneurship dan Praktik Pembuatan Lulur Organik Beras Ketan Hitam di SMA N 9 Samarinda Sianturi, Sister; Hanindita, Shafira
Jurnal Pengabdian Masyarakat Hutan Vol 3 No 1 (2025): Jurnal Pengabdian Masyarakat Hutan
Publisher : Program Studi Kehutanan, Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/kehutanan.v3i1.329

Abstract

Ecopreneurship, or environment-based entrepreneurship, offers a strategic approach to thematic training aimed at fostering environmental awareness and entrepreneurial skills. This study presents a training program conducted at SMA Negeri 9 Samarinda, which introduced high school students to ecopreneurship through the development of an organik body scrub made from black glutinous rice. The program consisted of two core components: (1) theoretical instruction on organik products and ecopreneurship concepts, and (2) hands-on practice in creating the body scrub. Effectiveness was assessed through pre- and post-training evaluations, which revealed a significant increase in student knowledge—from an average pre-test score of 64.11 to a post-test average of 78.75. Students exhibited strong engagement and active participation throughout the sessions. They also developed and presented simple promotional posters for their products, promoting soft skills such as public speaking and creative visual design. This initiative demonstrates the potential of ecopreneurship education to inspire interest in environmental sustainability and creative entrepreneurship among youth