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All Journal Jurnal Gizi dan Pangan Jurnal Gizi Jurnal Kesehatan Masyarakat Indonesia MEDIA MEDIKA INDONESIANA Journal of Nutrition and Health JURNAL GIZI INDONESIA Journal of Nutrition College Indonesian Journal of Cancer Chemoprevention Sari Pediatri Universa Medicina Health Notions Jurnal Ilmu Kefarmasian Indonesia Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) Berita Kedokteran Masyarakat
Hertanto Wahyu Subagio
Clinical Nutrition Department, Medical Faculty, Diponegoro University
Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Medica Hospitalia

 1 
Hubungan Lingkar Lengan Atas Ibu Hamil Genap Bulan Dengan Ukuran Plasenta Dan Berat Bayi Lahir Eunika Lusiana; Hertanto Wahyu Subagio; Besari Adi Pramono
Medica Hospitalia : Journal of Clinical Medicine Vol. 4 No. 2 (2017): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.329 KB) | DOI: 10.36408/mhjcm.v4i2.317

Abstract

Latar belakang: Status gizi ibu yang tercermin dari Lingkar Lengan Atas (LILA) sangat mempengaruhi status gizi bayi terutama Berat Bayi Lahir (BBL). Malnutrisi intrauterin mengakibatkan morbiditas dan mortalitas perinatal serta terjadinya penyakit degeneratif yang dikenal dengan Foetal Origin Adult Disease (FOAD). Plasenta merupakan organ untuk mencari riwayat malnutrisi intrauterin.Tujuan: Mencari hubungan LILA ibu hamil dengan ukuran plasenta (berat plasenta dan luas plasenta) dan BBL.Metode: Lima puluh subyek penelitian yang memenuhi kriteria inklusi dan eksklusi, diambil secara consecutive sampling, dari pasien yang melahirkan  selama bulan April – Mei 2016 di RS Dr. Kariadi, Puskesmas Halmahera, Puskesmas Ngresep dan RSIA Bunda. Data  meliputi LILA, berat plasenta, luas plasenta dan BBL. Untuk mempelajari hubungan antara variabel independen (LILA, berat plasenta dan luas plasenta) dengan variabel dependen (BBL) dilakukan analisis uji korelasi. Analisis regresi linier multiple digunakan untuk mengetahui hubungan antara seluruh variabel independen dengan dependen secara simultan.Hasil: Ada hubungan antara LILA dengan BBL (r = 0,762; p = 0,0001), berat plasenta (r = 0,673; p = 0,0001) dan luas plasenta (r = 0,636; p = 0,0001). Pada analisis multivariat ternyata LILA, berat plasenta dan luas plasenta secara berturut-turut berpengaruh terhadap BBL. Nilai r2 = 0,237, artinya pengaruh LILA, berat plasenta dan luas  plasenta terhadap BBL sebesar 23,7%.Simpulan: LILA berhubungan secara positif dengan BBL, berat plasenta dan luas plasenta.Kata kunci: LILA, BBL, berat plasenta, luas plasenta.
Pengaruh Suplementasi Ekstrak Ikan Gabus (Channa Striata ) Terhadap Kadar Albumin, Kolesterol, Waktu Remisi Dan Kejadian Relaps Pada Anak Sindrom Nefrotik Muhammad Heru Muryawan; Ag Soemantri; Hertanto Wahyu Subagio; Nanan Sekarwana
Medica Hospitalia : Journal of Clinical Medicine Vol. 6 No. 1 (2019): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.786 KB) | DOI: 10.36408/mhjcm.v6i1.371

Abstract

Background : Nephrotic syndrome (NS) is common in children with massive proteinuria causing severe hypoalbuminemia and hypercholesterolemia. Various attempts are required to increase albunin serum, accelerate remission time, and prevent relapse in order to reduce kidney damage. The Channa striata extract is known for its benefits in increasing albumin levels. Objective : To prove channa striata extract supplementation effect in increasing albumin serum, reducing cholesterol serum, remission and relapse time in children with NS. Methods :This is a double blind randomized controlled trial pre and post test design, 60 children with NS aged 1-15 years were included. A total of 500 mg / day channa striata extract capsule supplementation were administrated 2x1 to the treatment group for 21 days, meanwhile control group received placebo. Children with other chronic disease and with steroid resistance NS were excluded. The outcomes were serum albumin, cholesterol levels, remission and relapse time. Analysis data of albumin and cholesterol was performed by using unpaired t test and Mann-Whitney test. Remission and relapse times were analyzed by chi-square test. Results: There are 60 children met the inclusion criteria (32 children received Channa extract and 28 children were given placebo). Increased albumin level after supplementation was 3,6+0.8 g/dL(p<0.05) higher compared to placebo group 3,2+0.8 g/dL( p<0.05). Decreased levels of total cholesterol between the two groups were not significant (p>0.05). The treatment group remission time was 8.4+2.9 days, 11.0+3.7 day faster compared to placebo group (p <0.05). Relapse in the treatment group (21.4%) were similar to the placebo group (21.9%) (p> 0.05). Conclusions: Channa striata extract supplementation 3x500 mg/day for 21 days is effective to increase albumin levels and accelerate remission time significantly. Decreased cholesterol serum and relapse were not significant. Keywords: nephrotic syndrome, channa striata extract, albumin, cholesterol, remission time, relapse Latar Belakang: Sindrom nefrotik (SN) banyak dijumpai pada anak dengan proteinuria masif yang menyebabkan hipoalbuminemia berat dan hiperkolesterolemia. Diperlukan upaya meningkatkan kadar albumin, mempercepat waktu remisi dan mencegah relaps guna mengurangi kerusakan ginjal. Ekstrak ikan gabus (EIG)/Channa striata) diketahui dapat meningkatkan kadar albumin. Tujuan: Membuktikan pengaruh suplementasi EIG terhadap peningkatan kadar albumin, penurunan kolesterol,waktu remisi dan kejadian relaps pada anak SN. Metode: Penelitian randomized controlled trial pre and post test design, tersamar ganda, dilakukan mulai Maret-November 2017 terhadap 70 anak SN usia 1-15 tahun, terbagi menjadi 35 anak kelompok suplementasi EIG 2x500 mg/hari selama 21 hari; 35 anak kelompok kontrol. Anak dengan penyakit kronis lain, anak dengan resisten steroid di eksklusi. Luaran yang diteliti adalah kadar albumin, kolesterol, waktu remisi dan kejadian relaps. Analisis data kadar albumin dan kolesterol dengan uji t tidak berpasangan dan uji Mann-Whitney, waktu remisi dan kejadian relaps dengan uji Chi-Square. Hasil: Enam puluh subyek masuk kriteria penelitian (32 di kelompok EIG dan 28 di kelompok plasebo). Peningkatan kadar albumin setelah pemberian EIG 3,6+0,8 g/dL lebih tinggi dibanding kontrol 3,2+0,8 g/dL (p<0,05). Penurunan kadar kolesterol total diantara dua kelompok didapatkan nilai p>0,05. Waktu remisi kelompok EIG 8,4+2,9 hari, lebih cepat dibanding kontrol 11,0+3,7 hari (p<0,05). Kejadian relaps kelompok EIG (21,4%) sama dengan kontrol (21,9%) (p>0,05). Kesimpulan: Suplementasi EIG 2x500 mg/hari selama 21 hari, efektif meningkatkan kadar albumin dan mempercepat waktu remisi secara bermakna. Penurunan kadar kolesterol dan kejadian relaps tidak bermakna. Kata kunci: sindrom nefrotik, ekstrak ikan gabus, albumin, kolesterol, waktu remisi, relaps
Difference Between BMI At Admission and Discharge and NIHSS at Admission and Discharge In Iscemic Stroke Patients at Dr.Kariadi Horpital Fauziah, Annisa; Subagio, Hertanto Wahyu; Nugrohowati, Annta Kern; SS, Darmono; Probosari, Enny
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.777

Abstract

BACKGROUND : Hospitalized patients are at risk for malnutrition. Decreased BMI (Body Mass Index) in stroke patients is negatively correlated with patient outcomes. Studies on differences in BMI and NIHSS (National Institutes of Health Stroke Scale) at admission and discharge in stroke patients have not been conducted in Indonesia. OBJECTIVE: To describe the difference between BMI and NIHSS at admission and discharge in ischemic stroke patients at Dr. Kariadi hospital METHOD : An observational study on 49 hospitalized ischemic stroke patients at the Stroke Unit of dr. Kariadi hospital. Outcomes were measured using the National Institutes of Stroke Scale (NIHSS). Data was collected from the patient's medical record and analyzed using Paired Sample t Test. RESULT : There was no significant difference between BMI at admission and discharge (p = 0.161). There was a significant difference between the NIHSS at the time of admission and at the time of discharge (p= 0.014). CONCLUSION : There is no significant difference between BMI at admission and discharge. There is functional improvement in ischemic stroke patients during treatment
Co-Authors Adriyan Pramono Ag Soemantri Agustinus Soemantri Ali Manfaluthi Ahmad Amalia Sukmadianti Amalia Sukmadianti Amin Samiasih Aminullah, Yusuf Annisa Fauziah, Annisa Annta Kern Annta Kern Nugrohowati Annta Kern Nugrohowati Apoina Kartini Apoina Kartini Apriyanto, Denny Aris Sudiyanto Aryu Candra Atmaja, Diana Bagoes Widjanarko Banundari Rachmawati Besari Adi Pramono Binar Panunggal Budi Santoso Camelia Bomaztika Sari Darmono SS Darmono SS Dewi Masitha Dewi, Amalia Andansari Dewi, Clara Rashinta Dian Ratna Sawitri Dodik Tugasworo Dwi Pudjonarko EDI DHARMANA Edi Dharmana Enny Probosari Enny Probosari Etisa Adi Murbawani Eunika Lusiana Fatimah Muis, Siti Febe Christianto Febe Christianto Febriana Rahmawati Hardhono Susanto Hardian Hardian Hardono Susanto, Hardono Hartanti Sandi Wijayanti Henna Rya Sunomo Heri Nugroho Jennifer Setiawan Joriandhita Ramadhan Lisyani Suromo Luciana Sutanto Lukman, Petrin Redayani M Herumuryawan M Mexitalia M Sakundarno Maharatih, Gusti Ayu MARTHA ARDIARIA Martha Irene Kartasurya Mexitalia Mexitalia Minidian Fasitasari Mohammad Zen Rahfiludin MR Arientasari Himawan MS Anam Muchlis Achsan Udji Muchlis Ahsan Udji Sofro Muhammad Heru Muryawan Muhammad Sulchan Muji Mulyati Nanan Sekarwana Natalia Dewi Wardani Nathalia Safitri Niken Puruhita Noor Pramono Nugrahaningsih Nugrahaningsih Nurrohmiati, Siti Nurul Ratna Mutu Manikam Nuryanto Nuryanto Nyoman Suci Widyastiti Phitra Sekar Dianggra Pusaka, Semerdanta Retnaningsih - Rimahardika, Rosita Riwanto Rosa Kristiansen Roziana Roziana, Roziana RRJ. Sri Djokomoeljanto Santi Rahayu Santosa, Damai SARJADI SARJADI Septiawan, Debree Sofyan Harahap Sri Djokomoeljanto suhartono - Suhartono Suhartono Suhartono, Suhartono Suharyo Hadisaputro Suharyo Hadisaputro Suprapti, Rini Suratman Suratman Susilani, Amalina Tri Susilo, Kezia Natalia Daniast Taufik Hilmansyah Tri Indah Winarni Tugasworo Pramukarso, Dodik Ulfa, Viny Rosaliana Wendiranti, Catra Ibriza Widiastuti, Maria Immaculata Widya Budiarni Wijayanto Wijayanto Wiwid Widiyatni Wiwid Widiyatni, Wiwid Yuliyani, Ni Nyoman Sri Zulfikar Naftali, Zulfikar