Article Per Year (5 Year)
p-Index From 2021 - 2026
2.304
P-Index
This Author published in this journals
All Journal Medical Journal of Indonesia The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Belitung Nursing Journal Narra J
Bambang Supriyatno
Department Of Child Health, Faculty Of Medicine, Universitas Indonesia, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 34 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Narra J

 1 
Neutrophil-to-lymphocyte ratio as a predictor of low cardiac output syndrome after open heart surgery in children with congenital heart disease Laila, Dewi S.; Perdana, Andri; Permatasari, Ruth K.; Kadim, Muzal; Advani, Najib; Supriyatno, Bambang; Chozie, Novie A.; Djer, Mulyadi M.
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.736

Abstract

Neutrophil-to-lymphocyte ratio (NLR) as a predictor in determining low cardiac output syndrome (LCOS) has not been widely reported. The aim of this study was to explore the role of pre-surgery, 0-, 4-, and 8-hour post-surgery NLR as predictors of LCOS incidence after open heart surgery in children with congenital heart disease (CHD). This study used a prognostic test with a prospective cohort design and was conducted from December 2020 until June 2021 at the cardiac intensive care unit (CICU) of Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. The subject consisted of children aged one month to 18 years who underwent open heart surgery using a cardiopulmonary bypass (CPB) machine. A receiver operating characteristic curve was applied to identify the predictive performance of NLR for poor outcomes (LCOS incidence). Out of 90 patients included in the study, 25 (27.8%) of them developed LCOS between 3 to 53 hours post-surgery. All NLR values (pre-surgery and 0-, 4-, and 8-hours post-surgery) were associated with the incidence of LCOS. Pre-surgery NLR (cut-off value ≥0.88) had a fair predictive value (area under curve (AUC) 70; 95%CI: 57–83) for predicting LCOS incidence with sensitivity and specificity of 64% and 64.62%, respectively. NLR 0-hour post-surgery (cut-off value ≥4.73) had a good predictive value (AUC 81; 95%CI: 69–94) for predicting LCOS incidence, with 80% sensitivity and 80% specificity. NLR 4- and 8-hours post-surgery had very good predictive values (AUC 97%; 95%CI: 92–100 and 98; 95%CI: 94–100, respectively), with cut-off values ≥6.19 and ≥6.78, had the same 92% sensitivity and the same 96% sensitivity. The presence of LCOS was associated with mortality (odds ratio of 5.11 with 95%CI: 3.09–8.46). This study highlights that pre-surgery, 0-, 4-, and 8-hours post-surgery NLR can be predictors of LCOS after open heart surgery in children with CHD.
Co-Authors Adhi Teguh Perma Iskandar Ahmad Kautsar Ahmad Syafiq Alan R Tumbelaka Amir S. Madjid, Amir S. Anisa Rahmadhany Antonius H. Pudjiadi Aria Kekalih Arwin AP Akib Bambang Madiyono Bambang Tridjadja Bina Akura Chozie, Novie A. Citra Estetika Damayanti R. Syarif Damayanti Rusli Sjarif Darmawan B Setyanto Darmawan B. Setyanto Desy Dewi Saraswati Dewi I. Santoso Dewi Kartika Suryani Dewi Sukmawati Dewi Wulandari Dina Medina Dina Muktiarti, Dina Djajadiman Gatot Djer, Mulyadi Muhammad Eka Laksmi Hidayati, Eka Laksmi Ellen P. Gandaputra Endang Windiastuti Evita KB Ifran Faisal Yunus Finny Fitry Yani Fiolita I. Sutjipto Gunanti . Hanifah Oswari Hartono Gunardi Hartono Gunardi Heda Melinda D Nataprawira Heriandi Sutadi I Gusti Lanang Sidiartha I. Boediman Ida Bagus Subanada IGAN Partiwi Ika Karlina Idris Ina Rochayati Ina Susianti Timan Ina Susianti Timan Iqbal Zein Assyidiqie Irlisnia Irlisnia Irma Sapriani Iskandar, Adhi Teguh Perma Joedo Prihartono Joedo Prihartono Jose RL Batubara Kautsar, Ahmad Laila, Dewi S. Lisa Adhia Garina Mardjanis Said Matahari Harumdini Mulya Rahma Karyanti, Mulya Rahma Mulyadi M. Djer Mulyadi M. Djer Mulyadi M. Djer Munar Lubis Muzal Kadim Najib Advani Najib Advani Najib Advani Nalapraya , Widhy Yudistira Nani Nurhaeni Nastiti Kaswandani Nastiti N Rahajoe Nastiti N. Rahajoe Nia Kurniati Nia Kurniati Noenoeng Rahajoe Nyimas Heny Purwati Oke Rina Ramayani Partini Pudjiastuti Trihono Perdana, Andri Permatasari, Ruth K. Piprim Basarah Yanuarso, Piprim Basarah Rahmadhany, Anisa Rini Andriani Rini Andriani Rini Andriani Rini Asterina Rini Sekartini Risma Kerina Kaban Risma Kerina Kaban, Risma Kerina Rismala Dewi Riza Sahyuni Rusmala Deviani Rusmala Deviani Santoso, Dewi Irawati Soeria Sjawitri P Siregar Sri R.S. Hadinegoro Sudigdo Sastroasmoro Sudung O Pardede, Sudung O Sudung O. Pardede, Sudung O. Sudung Oloan Pardede Suhendro Sukman Tulus Putra Sutjipto, Fiolita Indranita Syahrial MH Tetty Yuniarti Tetty Yuniati Titis Prawitasari, Titis Wahyuni Indawati Yeni Rustina Yeni Rustina Yovita Ananta Zakiudin Munasir