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Journal : Medula

Hubungan Antara Kadar D-Dimer dengan Angka Mortalitas pada Pasien Dewasa Terkonfirmasi Coronavirus Disease 19 di RSUD Abdul Moeloek Bandar Lampung Periode Tahun 2020 – 2021.docx Attila Firjatullah, Muhammad Daffa; Tjiptaningrum, Agustyas; Putri, Giska Tri
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1055

Abstract

Lampung is one of the regions with the highest Case Fatality Rate (CFR) in Indonesia, which was 7.7% on September 16, 2021. Several studies have shown that D-Dimer levels influenced the mortality of confirmed Covid-19 patients. This study aimed to analyze the correlation between D-Dimer levels and the mortality rate of confirmed Covid-19 adult patients. This research was an observational analytic study using a cross-sectional approach. The population of this study was all confirmed covid-19 adult patients who fulfilled the inclusion and exclusion criteria in Abdul Moeloek Hospital Medical Record Installation from 2020 to 2021. The samples were taken using simple random technique. Data collected were D-Dimer level, mortality rate, and patient’s personal information. Data were analyzed by Chi-Square using statistical data processing program. There were 94 subjects admitted in our study, divided into groups of survivors and non-survivors. From the non-survivors’ group, 43 (91%) subjects had a high D-Dimer level. The Chi-Square analysis showed a correlation between D-Dimer levels and the mortality rate of Covid-19 patients (p-value = 0,001). Statistically, there was a significant correlation between D-Dimer levels and the mortality rate of confirmed Covid-19 patients.
Pengaruh HbA1c Terhadap Profil Lipid pada Pasien Diabetes Melitus Tipe 2 Suci, Maghfirly Juniarti Eka; Tjiptaningrum, Agustyas; Setiawan, Gigih; Kurniati, Intanri
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1263

Abstract

Diabetes Mellitus (DM) is characterized by a state of hyperglycemia due to insulin resistance, decreased insulin production, or both of these conditions which are classified into metabolic diseases. When checking the condition of type 2 DM, HbA1c can be checked as an indicator. High and uncontrolled HbA1c levels will cause disturbances in lipid profiles such as increased triglycerides, LDL, total cholesterol, and decreased HDL. The purpose of this study is to determine whether or not there is an effect of HbA1c on lipid profiles in type 2 DM patients. This method uses scientific publication search media such as Google Scholar, Pubmed, and old medical scientific journals using the keywords “lipid profile, HbA1c, type 2 diabetes mellitus, and dyslipidemia” obtained 15,700 articles and scientific journals. In patients with type 2 diabetes mellitus, glycemic control can be determined by HbA1c examination, high HbA1c levels are associated with disruption of lipid profile levels. The results of the study discuss the effect of HbA1c levels on lipid profiles in patients with type 2 diabetes and determine the relationship between the two.
Hubungan Rasio Neutrofil Limfosit (RNL) Dengan Lama Rawat Inap Pada Pasien Pneumonia Di Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Provinsi Lampung Julianti, Dinul Aliya; Sangging, Putu Ristyaning Ayu; Pardilawati, Citra Yuliyanda; Tjiptaningrum, Agustyas
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1316

Abstract

Pneumonia is an acute infection of the lung tissue due to bacteria, viruses, and fungi. Increased RNL values in pneumonia patients are biomarkers to systemic inflammatory responses that are easily quantified, inexpensive, and easily interpretable in the prognosis of pneumonia patients associated with length of stay. However, there is still not much relevant amount of research, and its application in daily practice is still minimal. This study aimed to identify the relationship of NLR with the length of hospitalization in pneumonia patients. This study used a cross sectional design. The data collection technique is a total sampling with a sample size of 39 patients. The research location is at Dr. H. Abdul Moeloek Regional General Hospital, Lampung Province and will take place in July-December 2022. The independent variable is RNL, while the dependent variable is the length of stay. Data obtained from the results of laboratory supporting examinations in the medical records of pneumonia patients. The collected data were then analyzed using the Chi-square test with a CI of 95%. The results showed that the majority of patients came from the age group of 51-60 years (51.3%) and were male (61%). The average pneumonia patient had a high ANC value (9,260) and a normal ALC (1,244) so that a high NLR average (10,067) was obtained with an average long stay (6 days). There is a relationship between NLR and length of stay in pneumonia patients at Dr. H. Abdul Moeloek Regional General Hospital, Lampung Province (p<0.05).