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All Journal e-GIGI e-CliniC Jurnal e-Biomedik JURNAL BIOMEDIK Jurnal Keperawatan Sari Pediatri Paediatrica Indonesiana Jurnal Kesehatan Medika Saintika Jurnal Kedokteran Klinik Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Gema Wiralodra Jurnal Kesehatan Tambusai Medical Scope Journal (MSJ) Sam Ratulangi Journal of Public Health Indonesian Journal of Public Health and Community Medicine
Adrian Umboh
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Journal : Paediatrica Indonesiana

 1 
Effect of intravenous gentamicin on urinary calcium excretion in newborns Kurniawan Tan; Adrian Umboh; Ari Runtunuwu
Paediatrica Indonesiana Vol 55 No 4 (2015): July 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.283 KB) | DOI: 10.14238/pi55.4.2015.185-8

Abstract

Background Studies in newborns and animals have shown that gentamicin increases urinary calcium excretion. New recommendation for gentamicin in newborns is administered intravenously 36-48 hourly. Subsequent to this new recommendation, there have been no further studies on the effects of extended gentamicin dosage on urinary calcium excretion in newborns.Objective To assess the effect of intravenous gentamicin on urinary calcium excretion in newborns.Methods This pretest – posttest study was done in the Neonatology Division of Prof. DR. R. D. Kandou Hospital, Manado, from August to November 2013. Subjects were full-term newborns who received intravenous gentamicin every 36 hours and whose parents provided informed consent. We excluded newborns with asphyxia and cardiovascular shock, also those who received diuretics or steroids. Urine spot collection was done before, after the first dose, and after the second dose of intravenous gentamicin. Urinary calcium and creatinine levels were measuerd. Urine calcium excretion was defined as the ratio of urinary calcium to creatinine level.Results Of 28 newborns, there were 16 males and 12 females. The median of urine calcium creatinine ratio before intravenous gentamicin was 0.021 (range 0.004 to 0.071) mg/mg. After first dose of gentamicin, the median ratio was 0.043 (range 0.009 to 0.156) mg/mg, and after the second dose of gentamicin, the median ratio was 0.144 (range 0.015 to 1.160) mg/mg.Conclusion There is a significant increase in urinary calcium excretion after the first and second doses of intravenous gentamicin. Furthermore, a cumulative effect of gentamicin on urinary calcium excretion is observed after the second dose. 
Developmental performance in small for gestational age children with and without catch-up growth Hesti Lestari; Suryani As’ad; Irawan Yusuf; Adrian Umboh; Andi Dwi Bahagia Febriani
Paediatrica Indonesiana Vol 55 No 4 (2015): July 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.027 KB) | DOI: 10.14238/pi55.4.2015.199-202

Abstract

Background Infants born small for gestational age (SGA) have an increased risk of developmental delay. The influence of catch-up growth on developmental function remains unknown.Objective To compare the development of SGA children with and without catch-up growth.Methods We conducted a cross-sectional study in Manado from March to July 2013. Subjects were children aged 2-3 years, that born SGA from March 2010 to June 2011 in Prof. Dr. R.D. Kandou Hospital. Catch-up growth was defined as height-for-age more than -2SD on the 2006 WHO growth chart, and subjects were classified into the with and without catch-up growth groups. Developmental status was assessed using the Ages and Stages Questionnaire (ASQ) 3rd edition, through interviews with parents. We compared the developmental status between the with and without catch-up growth groups used Mann-Whitney test with a significance level of P < 0.05.Results Of the 112 SGA children, 66 (58.9%) had catch-up growth and 46 (41.1%) did not. The SGA children with catch up growth had significant better development performances of gross motor, fine motor, and problem solving. The mean ASQ centiles of the with and without catch-up groups were 55.15 (SD 7.843) [95%CI 53.52 to 57.08] and 48.80 (SD 11.264) [95%CI 45.46 to 52.15] in gross motor, respectively; 42.5 (SD 13.163) [95%CI 39.26 to 45.74] and 32.93 (SD 14.475) [95%CI 28.64 to 37.23] in fine motor, respectively; 46.74 (SD 13.112) [95%CI 43.52 to 49.97] and 40.98 (SD 11.480) [95%CI 37.57 to 44.39] in problem solving, respectively.Conclusion Small for gestational age children with catch-up growth have significantly better gross motor, fine motor, and problem-solving performance than those without catch-up growth.
Enuresis profile in 6-7 year-old children at five elementary schools in Sario district, Manado Adrian Umboh; Astrid A. Malonda; T. A. Sudjono
Paediatrica Indonesiana Vol 47 No 6 (2007): November 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.005 KB) | DOI: 10.14238/pi47.6.2007.261-4

Abstract

Background Enuresis is inappropriate urination by a child whohas reached an age which bladder control is expected. The etiologyis unknown, but some factors influence it.Objective To identify enuresis profiles in 6-7 year-old children.Methods It was a descriptive prospective study at five elementaryschools in Sario district Manado from May to September 2005.Data were obtained by questionnaires.Results Out of 63 children with enuresis, 67% aged 6 years, 57%were male, 37% had enuresis more than 4 times a month, 64%had enuresis more than 8 times a day. No one had complaint ofurinary tract infection. Most cases (70%) had enuresis since birth,51% of cases got toilet training at the age of 3-4 years old. Noneof enuretic children had divorced parents. Nocturnal enuresisoccurred in 81% of cases, 54% of cases had 4 family members,30% of cases had family history of enuresis.Conclusions Enuresis in 6-7 year old children is most commonlyseen in boys. Enuresis mostly happens for more than 4 times in amonth with urination more than 8 times a day. There is nocomplaint of urinary tract infection. Most of the cases haveenuresis during nighttime. Toilet training starts by the age 3-4years old. Most cases had enuresis since birth. They came from afamily with 4 family members, and in most situation no familyhistory of enuresis is found.
Birth weight and blood pressure in first-grade elementary school students: A preliminary study Adrian Umboh; Stefanus Gunawan
Paediatrica Indonesiana Vol 45 No 6 (2005): November 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.6.2005.251-5

Abstract

Background Fetal programming theory reveals that low birthweight is associated with higher risks of hypertension and cardio-vascular diseases in the adulthood.Objective To study the difference in blood pressure among first-grade students of different birth weight groups.Methods A cross-sectional study was performed. Blood pressureof 214 healthy first-grade elementary school students (102 malesand 112 females) in Bunaken Subdistrict, Manado, Indonesia, wasmeasured using a standard sphygmomanometer with appropriatecuff for arm size. Two readings were taken. Parents were asked tocomplete a questionnaire concerning the information on birth weightand length and confirmed by retrieving the record on a growthchart and/or a maternal-child health book. The subjects were di-vided into 6 groups according to their birth weight. The differencesin blood pressure values between birth weight groups were exam-ined by ANOVA.Results Systolic blood pressures were significantly higher in the<2500 g birth weight group (100.73+9.99 mmHg vs. 93.70+8.29mmHg) and in the 2500-<3000 g birth weight group compared tothose of the 3500-<4000 g one (99.56+9.14 mmHg vs. 93.70+8.29mmHg) with a P of 0.048 and 0.014, respectively. There was nodifference between diastolic blood pressure and birth weight.Conclusion Our study showed that the lower birth weight grouptends to have a higher systolic blood pressure than that of childrenwith normal birth weight
Fecal short-chain fatty acids level and pediatric relapsing nephrotic syndrome Manoppo, Jeanette Irene Christiene; Yolanda, Natharina; Umboh, Adrian
Paediatrica Indonesiana Vol. 64 No. 4 (2024): July 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.4.2024.332-8

Abstract

Background The gut microbiota has a potential role in the development of nephrotic syndrome. Fecal short-chain fatty acid (SCFA) levels are representative of gut microbiota activity. Objective To assess for potential associations of fecal short-chain fatty acid levels in pediatric relapsing nephrotic syndrome. Methods This cross-sectional study was done on patients at the Pediatric Nephrology Subdivision of Prof. Dr. R.D. Kandou General Hospital, a referral hospital in Manado, Indonesia. Subjects were 25 patients aged less than 18 years with nephrotic syndrome (NS). We compared the levels of fecal acetic acid, propionic acid, butyric acid percentage, absolute butyric acid, and total short-chain fatty acid between children with relapsing and non-relapsing NS. A receiver operating characteristic (ROC) curve analysis was conducted to determine the significant SCFA cut-off level to diagnose NS. Results Comparison of fecal SCFAs between relapsing and non-relapsing NS groups showed significantly lower butyric acid percentages, absolute butyric acid level, and total SCFAs levels in the relapsing NS group, but not in acetic acid or propionic acid levels. Further multivariate analysis did not show a significant difference in total SCFA levels between relapsing and non-relapsing NS. Absolute butyric acid level had the strongest association with relapsing NS, with the highest predictive score. The absolute butyric acid cut-off value of 0.85 mg/mL had a high sensitivity (90%) and high specificity (93.3%) for predicting relapsing nephrotic syndrome. Conclusion Fecal acetic acid, propionic acid, and total short-chain fatty acid in stool are not associated with relapsing NS in children. However, fecal butyric acid measurements are inversely associated with relapsing NS.
Co-Authors Aaltje E. Manampiring Aaltje Ellen Manapiring Aaltje Manampiring Abram Babakal Adi Suryadinata Krisetya Alan J. Jufri Algi Reafanny Batara Amatus Yudi Ismanto Andi Dwi Bahagia Febriani Andrian Aldo Rantung Angelya Lumoindong Angie G. Roring, Angie G. Ango, Putri C. Ari L. Runtunuwu Ari Runtunuwu Astrid A. Malonda Baksh, Aida K. Bernadus, Janno Berty Bradly Chensilya Kusumanarwasti Christien Gloria Tutu Corona, Fidel Damaris, Damaris David E Kaunang David Kaunang Drova Grano Manorek Eka Patandianan Elia A. P. Hutapea Erling D. Kaunang Fatimawali . Frecillia Regina Herwanto Herwanto Hesti Lestari Hesti Lestari Hidayani, Agung R.E Hosang, Kevin H. Irawan Yusuf Iwan P. Wawointana, Iwan P. Jane A. Kalangi Jeanette I. Ch. Manoppo Jeanette I. Ch. Manoppo, Jeanette I.Ch. Manoppo Jenifer Andalangi Johannes Edwin Johnny Rompis Jose M. Mandei Jose M. Mandei Jully Kasie Kartini W. Adam Kristellina Tirtamulia Kromo, Lucky Kurniawan Tan Lasidi, Oktifani Devi Liow, Jackli Eugene Lonto, Jesica S. Lumingkewas, Pitter Handry Lydia Tendean Maki, Frindi Manopo, Berry R. Manoppo, Jeanette Irene Christiene Mantali, Rizqa Mantik, Keren E.K. Maria Fitricilia Marianne C. Jacobus, Marianne C. Matthew, Febriano Max F. J. Mantik Max F.J Mantik, Max F.J Natharina Yolanda, Natharina Nilawati, . Novie H. Rampengan Novie Homenta Rampengan, Novie Homenta Nurhayati Masloman Oktavin Yollah Umboh Paulina N. Gunawan Phan, Sardito Pinaria, Anthoneta S. Polii, Evan G. Praevilia M. Salendu Queen Mandang Reifanli M. Pai, Reifanli M. Robin Samuel Mamesah, Robin Samuel Rocky Wilar Rompies, Ronald Ronald Chandra Sabriani, Jehan Sanusi, Holly Sarah M. Warouw Sarah Warouw smanto, Yudi Stefanus Gunawan Stefanus Gunawan Stevanus Gunawan, Stevanus Surya, Welong S. Suryani As’ad Suwontopo, Marvin Leonardo T. A. Sudjono Taliwongso, Fernando Ch. Tandiawan, Ledy Tatipang, Pirania Ch. Umboh, Indria M. Umboh, Valetine Valentine Umboh Valentine Umboh, Valentine Vicky M. Kalangie, Vicky M. Vini Maleke, Vini Vivekenanda Pateda Vivekenanda Pateda Waworuntu, David S. Yanni, Iloh Devi Yolanda B. Bataha