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All Journal Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Jurnal Mandala Pengabdian Masyarakat Proceeding of Mulawarman Pharmaceuticals Conferences Journal of Pharmaceuticals and Natural Sciences Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan
Junaidin Junaidin
Fakultas Ekonomi Dan Bisnis Universitas Mulawarman, Samarinda, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Evaluasi Penggunaan Obat pada Pasien Artritis Gout di Instalasi Rawat Jalan Rumah Sakit Pupuk Kaltim Bontang Periode 2022: Evaluation of Drug Use in Gout Arthritis Patients in the Outpatients Installation of Pupuk Kaltim Bontang Hospital Period 2022 Silvia Ningsih Manurung; Hadi Kuncoro; Junaidin Junaidin
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 18 (2023): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v18i1.722

Abstract

Arthritis gout is a disease due to deposition of monosodium urate (MSU) crystals in the joints, kidneys, and other connective tissues as a result of hyperuricemia which can cause pain, swelling, impaired joint movement, and even tophi. Without rational treatment, there will be overdiagnosis and inadequate management which can aggravate gout. This study used observational studies and descriptive methods in 87 samples at the outpatient installation of Pupuk Kaltim Hospital Bontang Period 2022. The results of the study of patient characteristics based on age were most in the age group 46-55 years with a total of 25 patients (28.7%), based on gender more occurred in men with a total of 75 male patients (86.2%), based on the most symptoms were pain with a total of 69 cases (68.3%), and based on the highest diagnosis was acute gouty arthritis with a total of 76 patients (87.3%). The results showed that the most widely used antipyretic therapy was Allopurinol, which was used by 62 patients, followed by Colchicine which was used by 47 patients. For analgesic, antipyretic, and anti-inflammatory therapy, NSAIDs were used by 23 patients and Paracetamol was used by 6 patients. Keywords: gout arthritis, characteristics, treatment pattern Abstrak Artritis gout adalah penyakit akibat deposisi kristal monosodium urat (MSU) di sendi, ginjal, dan jaringan ikat lainnya sebagai akibat dari hiperurisemia yang dapat menimbulkan nyeri, bengkak, gangguan gerak sendi, dan bahkan tophi. Tanpa pengobatan yang rasional, akan terjadi overdiagnosis dan tata laksana yang tidak adekuat yang dapat memperparah gout. Penelitian ini menggunakan studi observasional dan dengan metode deskriptif pada 87 sampel di instalasi rawat jalan Rumah Sakit Pupuk Kaltim Bontang Periode 2022. Hasil penelitian karakteristik pasien berdasarkan usia terbanyak pada kelompok usia 46-55 tahun dengan jumlah 25 pasien (28,7%), berdasarkan jenis kelamin lebih banyak terjadi pada laki-laki dengan jumlah sebanyak 75 pasien laki-laki (86,2%), berdasarkan gejala paling banyak adalah nyeri dengan jumlah 69 kasus (68,3%), dan berdasarkan diagnosis paling tinggi adalah artritis gout akut dengan jumlah 76 pasien (87,3%). Hasil penelitian menunjukkan terapi antipirai yang paling banyak digunakan adalah Allopurinol yaitu sebanyak 62 pasien, diikuti dengan Kolkisin yang digunakan oleh 47 pasien. Untuk terapi analgesik, antipiretik, dan antiinflamasi golongan NSAID digunakan oleh 23 pasien dan Paracetamol digunakan oleh 6 pasien. Kata Kunci: artritis gout, karakteristik, pola pengobatan
Impact of Halal Information on Purchasing Decisions moderated Religiosity in Food and Beverage Provision Junaidin Junaidin; Syarifah Hudaya; Laode Rijai; Tetra Hidayat; Djoko Setyadi
Journal of Tropical Pharmacy and Chemistry Vol. 5 No. 3 (2021): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v5i3.304

Abstract

Halal information on Food and Beverage Preparations, analyze for influence on Purchasing Decisions. Novelty research is the Role of Moderation to the relationship of Halal Information to Purchasing Decisions. Using structural model equations (SEM), there is a positive and significant impact of Halal Information on Purchasing Decisions. There is a positive and considerable moderation of Religiosity to the relationship between Halal Information and Purchasing Decisions. The practical implications of the study's results, empirically proving that Halal Information listed on Food and Beverage Preparations led to an increase in Purchasing Decisions, and consumer Religiosity showed significant differences. Advice for Food and Beverage manufacturers to keep halal information on Food and Beverage Preparations because it affects positive buying decisions.
Potential and Constraints of Biopharmaceutical Plants in East Kalimantan Province Junaidin Junaidin; Supriatno Salam; Erwin Samsul
Journal of Tropical Pharmacy and Chemistry Vol. 6 No. 1 (2022): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v6i1.350

Abstract

Biopharmaceutical plants (drugs) in East Kalimantan Province have tremendous potential for the Farmers' Economy in particular and the Economy of Society in general. Farmers have not felt this potential because it faces existing obstacles. In this study, the Pharmaceutical Business Laboratory, Faculty of Pharmacy, Mulawarman University, will be analyzed for its role in finding solutions to existing obstacles. Research results are expected to be helpful in terms of the resource-advantage theory and in terms of Implications that can be done by Stakeholders, which aim that the potential of Biopharmaceutical Crops can bring the welfare of Farmers and Communities.
Karakterisasi Ekstrak Sambiloto (Andrographis panicullata Burn (f) Ness) dan Pegagan (Centella asiatica (l) Urban): Characterization Extract Sambiloto (Andrographis panicullata Burn (f) Ness) and Pegagan (Centella asiatica (l) Urban) Arman Rusman; Agung Endro Nugroho; Suwijiyo Pramono; Herman Herman; Muhammad Faisal; Junaidin Junaidin; Haeruddin Haeruddin
Jurnal Sains dan Kesehatan Vol. 5 No. 2 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i2.1749

Abstract

Sambiloto (Andrographis panicullata Burn (f) Ness) and Pegagan (Centella asiatica (l) Urban) are plants that have many benefits. Traditionally this plant is used as a medicine including insect bites and venomous snakes, dysentery, diabetes, venereal diseases, appendicitis, dirty blood, eczema, tonsil inflammation, ulcers and food poisoning. This study aims to determine the characterization of bitter and gotu kola extracts obtained from Girimulyo Village, Nanggulan District, Kulon Progo Regency which includes yield, drying loss, TLC profile, active compound content, and total flavonoid content. The extract characterization method follows the guidelines written in the Indonesian herbal famacopoeia (FHI). The results showed that the extracts of Sambiloto and Centella asiatica obtained the following data: the yield value of Sambiloto extract was 18.9% and Centella asiatica 21.7%, the organoleptic examination of the data obtained was in accordance with FHI standards, the drying shrinkage value of Sambiloto was 7.85 ± 0.60 and Centella asiatica 15.15 ± 0.42, qualitative analysis of Sambiloto and Centella asiatica extracts had the same rf values as the marker compounds, namely andrographolide for Sambiloto and asiaticoside for Centella asiatica. Measurement of andrographolid levels in Sambiloto extract showed a value of 32.56 ± 4.56 and Asiaticoside levels gotu kola extract showed a value of 15.01 ± 1.69. These results show that the bitter extracts and gotu kola taken from Girimulyo Village, Nanggulan District, Kulon Progo Regency comply with the standards written in the Indonesian herbal pharmacopoeia (FHI). Keywords: Sambiloto, Pegagan, Extract, Characterization Abstrak Sambiloto (Andrographis panicullata Burn (f) Ness) dan Pegagan (Centella asiatica (l) Urban) merupakan tanaman yang memiliki banyak manfaat. Secara tradisional tanaman ini digunakan sebagai obat diantaranya gigitan serangga dan ular berbisa, disentri, kencing manis, penyakit kelamin, radang usus buntu, darah kotor, eksema, radang tonsil, borok dan keracunan makanan. Penelitian ini bertujuan untuk mengetahui karakterisasi dari ekstrak sambiloto dan pegagan yang diperoleh dari Desa Girimulyo, Kecamatan Nanggulan, Kabupaten Kulon Progo yang meliputi rendemen, susut penegringan, profil KLT, kadar senyawa aktif, dan kadar flavonoid total. Metode karakterisasi ekstrak mengikuti panduan yang tertulis dalam famakope herbal Indonesia (FHI). Hasil penelitian menunjukan ekstrak sambiloto dan pegagan diperoleh data sebagai berikut: nilai rendemen ekstrak sambiloto 18,9 % dan pegagan 21,7%, pemeriksaan organoleptik data yang diperoleh sesuai dengan standar FHI, nilai susut pengeringan sambiloto 7,85±0,60% dan pegagan 15,15±0,42%, analisis kualitatif ekstrak sambiloto dan pegagan memiliki nilai rf yang sama dengan senyawa penanda yakni andrografolid untuk sambiloto dan asiaticosida untuk pegagan, pengukuran kadar andrografolid pada ekstrak sambiloto menunjukan nilai 32,56±4,56% dan kadar asiaticosida pada ekstrak pegagan menunjukan nilai 15,01±1,69%. Hasil tersebut menunjukan bahwa ekstrak sambiloto dan pegagan yang diambil dari Desa Girimulyo, Kecamatan Nanggulan, Kabupaten Kulon Progo sesuai dengan standar yang tertulis dalam farmakope herbal Indonesia (FHI). Kata Kunci: Sambiloto, Pegagan, Ekstrak, Karakterisasi
AKTIVITAS ANTIHIPERURISEMIA INFUSA DAUN KENIKIR (Cosmos caudatus Kunth.) PADA MODEL MENCIT HIPERURISEMIA TERINDUKSI KALIUM OKSONAT Erwin Samsul; Muhammad Romi Adipasa Pratama; Baso Didik Hikmawan; Herman Herman; Junaidin Junaidin; Lizma Febrina; Arsyik Ibrahim; Rolan Rusli; Hifdzur Rashif Rijai; Islamudin Ahmad; Arman Rusman; M. Arifuddin
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 9 No. 1 (2026): Jurnal Farmasi Medika/Pharmacy Medical Journal
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v9i1.66746

Abstract

Hyperuricemia is a metabolic disorder characterized by elevated serum uric acid levels due to excessive production or impaired excretion. Conventional therapy using xanthine oxidase inhibitors such as allopurinol is effective but may cause adverse effects with prolonged use. This study aimed to evaluate the antihyperuricemic activity of kenikir (Cosmos caudatus Kunth.) leaf infusion in a potassium oxonate-induced hyperuricemic mouse model. Phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, and tannins. Twenty-five male mice were randomly assigned into five groups (n=5): negative control (0.5% NaCMC), positive control (allopurinol 100 mg/kgBW), and three treatment groups receiving 10%, 15%, and 20% infusion. Hyperuricemia was induced using chicken liver juice and potassium oxonate (300 mg/kgBW). Each mouse received 0.5 mL orally. Blood uric acid levels were measured hourly for four hours using EasyTouch GCU. Statistical analysis using the Kruskal–Wallis test showed no significant difference among groups (p=0.220). However, descriptively, the 15% concentration demonstrated the highest percentage reduction (56.77%), followed by 20% (41.28%) and 10% (38.74%), compared with allopurinol (66.01%). These findings suggest that kenikir leaf infusion exhibits potential antihyperuricemic activity and supports further investigation with optimized dosing, larger sample size, and enzymatic validation. Keywords: Cosmos caudatus, hyperuricemia, potassium oxonate, uric acid
Pelatihan Desain Kemasan dan PIRT Dongkrak Daya Saing Produk Mangrove Bontang Karera Aryatika; Junaidin Junaidin; Jamil Anshory; Fahrul Rozi; Ummi Khuzaimah; Muhammad Nuzul Azhim Ash Shidiq; Rafael Fernando Dennis; Arya Yuliansyah; Marzev Tammam Attaqi; Salwa Zahra Maulidasari
Jurnal Mandala Pengabdian Masyarakat Vol. 7 No. 1 (2026): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v7i1.837

Abstract

Produk olahan mangrove (Sonneratia ovata) yang dikembangkan Pokdarwis Bontang Baru Bersinar masih menghadapi kendala daya saing akibat keterbatasan keterampilan desain kemasan dan belum optimalnya pemenuhan perizinan edar (PIRT). Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan peserta dalam mendesain kemasan menggunakan Canva sekaligus memperkuat pemahaman proses dan tahapan PIRT agar produk siap memasuki saluran distribusi formal. Kegiatan dilaksanakan 11 Oktober 2025 di Aula PKK Bontang Baru melalui empat sesi terstruktur: pretest, pelatihan (desain kemasan & sosialisasi PIRT), praktik Canva berkelompok, dan posttest. Instrumen evaluasi berupa 15 soal pilihan ganda, dengan kategorisasi skor: <60 (kurang), 60–80 (cukup/sedang), >80 (baik). Peserta kegiatan berjumlah 30 orang.  Hasil menunjukkan peningkatan pengetahuan yang bermakna setelah intervensi tidak ada peserta pada kategori “kurang” (0%), sementara kategori “baik” mencapai 47% dan “cukup/sedang” 53%. Selain itu, peserta menghasilkan keluaran praktis berupa berkas siap cetak (PDF dengan bleed/crop marks), aset digital resolusi tinggi, dan mockup promosi untuk varian sirup, selai, dan kerupuk. Disimpulkan bahwa kombinasi pelatihan Canva dan sosialisasi PIRT efektif meningkatkan kompetensi kognitif dan keterampilan praktis sekaligus kesiapan regulatif, sehingga berpotensi memperkuat shelf appeal dan akses pasar produk olahan mangrove.
Alkaloid Profiling of Kadamba (Mitragyna speciosa Korth. Havil.) Leaves through Chromatographic Separation and UV-Vis Spectrophotometery Analysis M. Arifuddin; Fatur Rahman Azmi; Iswahyudi Iswahyudi; Mahfuzun Bone; Harra Ismi Farrah; Hanggara Arifian; Maria Almeida; Arman Rusman; Erwin Samsul; Riki Riki; Hifdzur Rashif Rija&#039;i; Baso Didik Hikmawan; Junaidin Junaidin; Lizma Febrina; Rolan Rusli; Arsyik Ibrahim; Islamudin Ahmad; Herman Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 3 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i3.44

Abstract

Mitragyna speciosa Korth. berasal dari famili Rubiaceae yang banyak tumbuh di daratan negara-negara Asia Tenggara. Tumbuhan ini selain disebut Kratom, khususnya di daerah Kalimantan Timur dikenal juga dengan nama "Kadamba". Mitragyna speciosa Korth. belongs to the Rubiaceae family and is widely found in the mainland of Southeast Asian countries. This plant, known as Kratom, is also referred to as "Kadamba" in East Kalimantan. Kadamba has been used for generations as a traditional medicine and contains predominantly alkaloid compounds, which generally function as analgesics, antitussives, antidiarrheals, adrenergic agents, antimalarials, antibacterials, and antinociceptives. The aim of this research is to determine the isolation and identification methods for alkaloid compounds in Kadamba leaves. In this study, extraction was performed using methanol solvent, followed by fractionation using Vacuum Liquid Chromatography (VLC) and Column Chromatography (CC) with gradient eluents: 100% hexane, n-hexane : Ethyl Acetate (5:1, 1:1, 1:5), 100% Ethyl Acetate, Ethyl Acetate : Methanol (1:1, 1:5), and 100% Methanol. The compounds were then identified using Thin Layer Chromatography (TLC). The isolation process used preparative Thin Layer Chromatography (PTLC) with eluent n-hexane: ethyl acetate: 25% ammonia (6.5:3:0.5 v/v/v), and the spots were observed under UV light at 245 nm and 366 nm. The visible spots were sprayed with Dragendorff's reagent to identify the alkaloid compounds. The results showed that the UV-Vis spectrophotometric characterization of isolate B6-b had two peaks at wavelengths of 288 nm and 294 nm.
Co-Authors Agung Endro Nugroho Arman Rusman Arsyik Ibrahim Arsyik Ibrahim Arya Yuliansyah Baso Didik Hikmawan Djoko Setyadi Erwin Samsul Erwin Samsul Erwin Samsul Fahrul Rozi Fatur Rahman Azmi Hadi Kuncoro Haeruddin Haeruddin Hanggara Arifian Harra Ismi Farrah Herman Herman Herman Herman Hifdzur Rashif Rija&#039;i Hifdzur Rashif Rijai Islamudin Ahmad Islamudin Ahmad Iswahyudi Iswahyudi Jamil Anshory Karera Aryatika Laode Rijai Laode Rijai Lizma Febrina Lizma Febrina M. Arifuddin M. Arifuddin Mahfuzun Bone Maria Almeida Marzev Tammam Attaqi Muhammad Faisal Muhammad Nuzul Azhim Ash Shidiq Muhammad Romi Adipasa Pratama Rafael Fernando Dennis Riki Riki Rolan Rusli Rusman, Arman Salwa Zahra Maulidasari Silvia Ningsih Manurung Supriatno Salam Suwijiyo Pramono Syarifah Hudaya Tetra Hidayat Ummi Khuzaimah