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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Indonesian Journal of Chemistry JCRS (Journal of Community Research and Service) Jurnal Mandala Pharmacon Indonesia Journal of Pharmaceuticals and Natural Sciences Jurnal Sains dan Kesehatan Jurnal Abdita Naturafarm Jurnal Riseta Naturafarm Jurnal Riseta Soshum
Islamudin Ahmad
Universitas Mulawarman
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Analisis Zat Gizi Makro Biskuit Berbahan Dasar Sukun (Artocarpus altilis) dan Kelor (Moringa oleifera) Asriani; Kawareng, Andi Tenri; Ahmad, Islamudin
Jurnal Riseta Naturafarm Vol. 1 No. 2 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrn.v1i2.5359

Abstract

Biskuit merupakan salah satu alternatif sediaan pangan fungsional yang dapat dibuat dalam pemenuhan gizi. Jenis penelitian ini merupakan penelitian eksperimental yang dimulai dengan pembuatan formula pangan fungsional biskuit berbahan dasar buah sukun dan daun kelor, selanjutnya formula yang telah dibuat dievaluasi meliputi uji karakteristik kimia meliputi uji kadar air, kadar abu, kadar protein, kadar karbohidrat, kadar lemak, evaluasi fisik meliputi spread factor, uji sensorik, dan uji kadar total kalori. Hasil uji sensori yang dilakukan melalui penilaian responden terhadap rasa, aroma, warna, tekstur, dan nilai tingkat kesukaan terhadap biskuit tepung buah sukun dan tepung daun kelor yang didapatkan dari 5 formula biskuit yaitu sediaan formula E dengan konsentrasi daun kelor (6,25%): buah sukun (93,75%) lebih banyak disukai oleh responden. Hasil analisa karakteristik kimia, dan uji kadar total kalori, menunjukkan bahwa Kandungan zat gizi formulasi biskuit sampel E yaitu, kadar air 5,1748%, kadar abu, 2,2550%, protein 10,1208%, lemak 11,3039%, karbohidrat 71,1455%, glukosa 8,3420%, total kalori 426,8003 kkal. Uji karakteristik fisik sebesar 0,478 dan uji bobot jenis 1,1056 g/mL. Uji cemaran mikroba dilakukan dengan metode tuang, didapatkan angka lempeng total sebesar 0,24 x 103 koloni/g, sedangkan angka kapang khamir didapatkan 2 x 102 koloni/g
An Innovative Strategy for the Green Synthesis of Nanochitosan Using Plant Extracts and Their Possible Applications: A Review Riki, Riki; Ahmad, Islamudin; Herman, Herman; Ibrahim, Arsyik; Rusman, Arman; Samsul, Erwin; Rusli, Rolan; Arifuddin, Muhammad; Junaidin, Junaidin; Bone, Mahfuzun; Rijai, Hifdzur Rashif; Hikmawan, Baso Didik
Indonesian Journal of Chemistry Vol 25, No 2 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.100148

Abstract

The numerous applications of nanochitosan in a variety of sectors, including medicine, food, and agriculture, attract researchers to work toward the development of environmentally favorable, safe, and efficient synthesis methods. Currently, a biological approach is being developed to synthesize nanochitosan to address the limitations of conventional methods. The synthesis of biogenic pathways employs biological entities, including plant extracts and microorganisms, as nanoparticle-forming agents. The use of extracts is more desirable due to the simple working procedure, the absence of hazardous chemicals, the economic benefits, and the use of basic equipment. This article highlights the role of biomolecules in plant extracts, including polyphenols, terpenoids, citric acid, alkaloids, and polysaccharides, in the synthesis of nanochitosan. Nanoparticle preparation protocols and characterization using zeta potential analysis techniques, scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-visible spectroscopy, and Fourier transform infrared spectroscopy (FTIR) are briefly described. The potential applications of green nanochitosan are also discussed, considering the results of biological activity testing and the potential mechanisms associated with these activities. According to the results of numerous studies highlighted in this review, nanochitosan synthesis utilizing plant extracts appears to be a promising alternative approach to conventional methods.
Ethnomedicine Study on the Use of Medicinal Plants in Batak Ethnic Communities: Kajian Etnomedisin Pemanfaatan Tumbuhan Obat Pada Masyarakat Etnis Batak Rahmadani, Dessi; Harianti, Chita; Hasanah, Nurul; Arsya, Dinara Eza Syahadati; Zahrah, Nabila; Puspitawati, Ni Komang Anika; Sari, Karin Sopiya; Joshevine, Imelda; Filicia, Harfenas Althea; Asia, Nazha Delmora; Brigita, Vista; Ahmad, Islamudin
Jurnal Riseta Soshum Vol. 2 No. 1 (2025): J Riseta Soshum
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrs.v2i1.0717

Abstract

Ethnomedicine is the study of ethnobotany to reveal the knowledge and local wisdom of various ethnicities in order to maintain and maintain health. The Batak tribe is the largest tribe inhabiting the island of North Sumatra where the Batak ethnic community has a traditional medicine culture inherited by their ancestors from generation to generation in the form of a medical book with Batak script writing. The purpose of this paper is to convey the type or species of plants used in some disease treatments in Batak tribal communities and find out whether the type or species of plants used has data that supports its use as a treatment for a disease based on literature searches. The method used is systematic literature review. A comprehensive literature search was conducted using several databases such as Google Scholar, PubMeb, ScienceDirect, ResearchGate. Based on a study of known references, medicinal plants that are often used by the Batak tribe are plants from the Asteraceae, Fabaceae, Zingiberaceae, and Poaceae families to treat various diseases. A typical plant from the Batak tribe is the Pirdot plant (Saurauia bracteosa) which is usually used to reduce high blood pressure.
Aktivitas Antihiperglikemia Infusa Daun Sambung Nyawa (Gynura Procumbens) dengan Metode Toleransi Glukosa pada Mencit Jantan (Mus Musculus): Antihyperglycemic Activities of Sambung Nyawa Leaves (Gynura Procumbens) Infusion using a Glucose Tolerance Method in Male Mice (Mus Musculus) Ridhotulloh, Yusuf Isro; Rijai, Laode; Mus, Nurul Muhlisa; Arifuddin, M.; Ibrahim, Arsyik; Ahmad, Islamudin; Herman, Herman; Hikmawan, Baso Didik; Junaidin, Junaidin; Febrina, Lizma; Faisal, Muhammad; Rusman, Arman; Riki, Riki; Almeida, Maria; Bone, Mahfuzun; Arifian, Hanggara; Samsul, Erwin
Jurnal Sains dan Kesehatan Vol. 7 No. 2 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i2.2421

Abstract

Hyperglycemia is a condition where blood sugar increases significantly which can lead to diabetes mellitus. Sambung Nyawa (Gynura Procumbens) leaves are a plant that is empirically believed to reduce hyperglycemia and has been scientifically proven based on several studies, however there has been no research that provides information about sembung nyawa leaves in infusion form. This study aims to determine the content of secondary metabolites in the infusion of the leaves of Gynura Procumbens and its antihyperglycemia activity in male males. This study consisted of phytochemical and antihyperglycemia screening using a tolerance method induced by glucose monohydrate at a dose of 2g/kgBW. The test group consisted of a negative control group (Na CMC 1%), a positif group (Glibenclamide), and 3 groups of sambung nyawa leaf infusion (5%, 10%, 15%). The results of the research showed that the infusion of sembung nyawa leaves contained secondary metabolites, namely tannins, phenolics, flavonoids and saponins. The effect of reducing blood sugar levels in test animals showed a significant reduction (0.00<0.05) at a 10% concentration infusion compared to the negative control and not significant to the positive control. The conclusion shows that the infusion of sambung nyawa leaves has an antihyperglycemic effect. Keywords:          Antihyperglycemic, Sambung Nyawa Leaves, Glucose Monohydrate   Abstrak Hiperglikemia merupakan kondisi peningkatan gula darah yang cukup signifikan yang akan berubah menjadi kondisi diabetes mellitus. Daun sambung nyawa (Gynura Procumbens) merupakan tumbuhan yang dipercaya secara empiris menurunkan hiperglikemia dan terbukti secara ilmiah berdasarkan beberapa penelitian dalam bentuk ekstrak. Penelitian ini bertujuan mengetahui kandungan metabolit sekunder pada infusa daun sambung nyawa dan aktivitas antihiperglikemia pada mencit jantan. Penelitian ini terdiri dari skrining fitokimia dan antihiperglikemia menggunakan metode toleransi yang dinduksi glukosa monohidrat dengan dosis 2g/kgBB. Kelompok uji terdiri dari kelompok kontrol negatif (Na CMC 1%), positif (Glibenklamid), dan 3 kelompok infusa daun sembung nyawa (5%, 10%, 15%). Hasil penelitian menunjukkan infusa daun sambung nyawa mengandung metabolit sekunder yaitu tanin, fenolik, flavonoid dan saponin. Efek penurunan kadar gula darah pada hewan uji menunjukkan penurunan yang signifikan (0,00<0,05) pada infusa konsentrasi 10% dibandingkan dengan kontrol negatif dan tidak signifikan terhadap kontrol positif. Kesimpulan menunjukkan bahwa infusa daun sambung nyawa mempunyai efek antihiperglikemia. Kata Kunci:         Antihiperglikemia, Daun Sambung Nyawa, Glukosa Monohidrat  
Pharmacognostic and Toxicity Evaluation of Tabar Kedayan (Aristolochia papilifolia Ding Hou) Rootstock Lestari, Seftya Ayu; Iswahyudi, Iswahyudi; Arifuddin, M.; Prabowo, Wisnu Cahyo; Ahmad, Islamudin
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 2 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i2.6275

Abstract

Tabar kedayan (Aristolochia papillifolia Ding Hou.) is an endemic plant from northern Kalimantan and is widely used as traditional medicine by the Dayak people. This study aims to determine the pharmacognostic profile and toxicity data of Tabar Kedayan rootstock. The results showed macroscopically woody stem type, round stem shape, grooved or serrated stem surface, yellow-brown stem color, weak characteristic odor, bitter taste, microscopically found starch grains, calcium oxalate crystals, stone cells, cork cells, tracheids, and wood vessels. Fluorescence analysis under visible and ultraviolet light for Tabar Kedayan rootstock powder with different chemical reagents showed different fluorescence effects. Water content (0.466±0.01%), ethanol content (0.325±0.014%), moisture content (12.40±0.15%), total ash content (1.438±0.15%), and acid insoluble ash content (0.423±0.06%). Phytochemical screening of the chemical compounds of the ethanolic extract showed the presence of alkaloids, terpenoids, saponins, flavonoids, and tannins. The levels of total polyphenols (15.095 ± 1.11 µg GAE/mg sample), total flavonoids (0.184 ± 0.02 µg QE/mg sample), and total alkaloids (0.056 ± 0.02 µg QAE/mg sample) were found. The brine shrimp lethality (BSLT) assay results showed the highest LC50 value by the n-hexane fraction with an LC50 value of 17.660 µg/ml.
Pengayaan Polifenol Total dari Daun Kadamba Menggunakan Metode Ekstraksi Berbantu Mikrowave Berbasis Pelarut Hijau: Total Polyphenols Enrichment from Mitragyna speciosa Korth Havil Leaves Using Green Solvent Based Microwave-assisted Extraction Method Ahmad, Islamudin; Yusniah, Andi; Nur, Yuspian; Prabowo, Wisnu Cahyo; Herman
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15035

Abstract

The present study aims to optimize the natural deep eutectic solvent (NADES) as a green solvent-based microwave-assisted extraction (MAE) of total polyphenols content (TPC) from Mitragyna speciosa Korth Havil leaves using response surface methodology (RSM). Preparation of natural deep eutectic solvent (NADES) as a green solvent was performed by melting the two-component of malic acid and glucose using a magnetic stirrer. The leaves sample was extracted using the NADES-MAE method with various extraction conditions with four factors and three levels (Box Behnken Design) and optimized using RSM with licensed software of Design Expert V12. TPC was determined using a Folin-Ciocalteau reagent and absorbance was measured on a UV-VIS spectrophotometer at 770 nm and gallic acid as a standard. This study was obtained the optimum extraction conditions include: NADES ratio (malic acid: glucose) of 1:2 g/g, 50% microwave power, a solvent-sampel ratio of 12:1 mL/g, and extraction time for 7 minutes. The optimum conditions were obtained according to the equation formula: TPC = 165.17 – 33.97X1 + 38.36X2 – 6.08X3 + 16.12X4 – 62.77X1X2 + 79.61X12X2, where a R2 value = 0.7102 with a TPC prediction of 402.087±43.81 mg GAE/g sample. These conditions can be used to extract TPC from this plant efficiently, quickly, easily, and environmentally friendly.
Improving Health Literacy on Anemia Prevention Among Female Adolescents Through School-Based Interventions: Peningkatan Pengetahuan Remaja Putri Tentang Pencegahan Anemia Melalui Promosi Kesehatan Berbasis Sekolah Putri Sulistian, Salwah; Pratiwi Putri, Bella; Galih Rahmadana, Adly; Ahmad, Islamudin
Jurnal Abdita Naturafarm Vol. 2 No. 2 (2025): J Abdita Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jan.v2i2.5461

Abstract

Background: Adolescent girls are particularly vulnerable to iron-deficiency anemia due to increased nutritional demands during growth, regular iron loss through menstruation, and inadequate dietary intake. This condition negatively affects concentration, physical development, and overall productivity. Objective: This community engagement initiative aimed to improve adolescents’ knowledge and awareness of anemia prevention through school-based health education and iron supplementation. Methods: A school-based health promotion activity was conducted on June 17, 2025, at SMPN 11 Samarinda, involving 15 participants. The intervention included a pre-test, interactive educational session, post-test, and distribution of iron supplement tablets. Evaluation was carried out using the Wilcoxon test and participatory observation. Results: The intervention led to a statistically significant improvement in participants’ knowledge of anemia prevention (Z = -3.457; p < 0.001), with median scores increasing from 7 to 9 and interquartile range narrowing from 2 to 1, indicating more consistent understanding. Conclusion: This school-based educational initiative effectively enhanced health literacy among adolescent girls regarding anemia prevention and supports broader promotive-preventive health strategies aligned with national and global health agendas.
Workshop Pembuatan Gummy Candy Madu Kelulut Di Desa Bangun Rejo Kabupaten Kutai Kartanegara Samsul, Erwin; Junaidin, Junaidin; Rijai, Laode; Ibrahim, Arsyik; Herman, Herman; Rusli, Rolan; Ahmad, Islamudin; Febrina, Lizma; Farah, Harra Ismi; Hikmawan, Baso Didik; Rija’i, Hifdzur Rashif; Supriatno, Supriatno; Rusman, Arman; Almeida, Maria; Riki, Riki; Arifuddin, M; Bone, Mahfuzun; Arifian, Hanggara; Setiawaty, Agus
Journal of Community Research and Service Vol. 9 No. 2: July (2025)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jcrs.v9i2.69839

Abstract

A workshop on making gummy candy based on stingless bee honey was held in Bangun Rejo Village, Kutai Kartanegara Regency, as an effort to empower the community through innovation in locally processed food products. The aim of this activity was to improve the skills of MSME actors and village residents in producing stingless honey gummy candy, and to elevate the added value of local honey. The methods used included a short theoretical session about the composition of stingless bee honey and the technical process of gummy candy production, a live demonstration, group practice among participants, as well as evaluation via pre-test and post-test on understanding and skills. The workshop was attended by 50 participants from various MSMEs and community groups. Results showed that after training there was an increase in participant understanding by approximately 75% compared to before the training. Furthermore, participants succeeded in making gummy candy with a chewy texture, the natural sweetness of stingless bee honey, and a distinctive aroma that was well accepted in organoleptic tests. This workshop made a tangible contribution to local product diversification, increasing production capacity, and the potential enhancement of village income through signature products based on stingless bee.
Uji Stabilitas Warna dari Ekstrak Bunga Kiacret (Spathodea campanulata P. Beauv) Sebagai Sumber Alternatif Eksipien Farmasi Candrakanti, Bratandari Hana; Rija’i, Hifdzur Rashif; Ahmad, Islamudin
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 1 (2024): Jurnal Mandala Pharmacon Indonesia Special Issue for 18th Mulawarman Pharmaceu
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i1.464

Abstract

Kiacret (Spathodea campanulata P. Beauv.) merupakanl salah satul tanaman tropis yangl terdapat dil Indonesia. Padal bagian bunga dari tanaman kiacret mengandung pigmen warna antosianin. Oleh karena itu, dengan memanfaatkan bunga kiacret sebagai pewarna alami dapat meningkatkan nilai guna terhadap bunga kiacret. Penelitianl ini bertujuanl untuk mengetahuil perbedaan jumlah rendemen, kadarl total lantosianin, danl stabilitas zatl warna ekstrakl etanol 70%l dan l96% bunga kiacret terhadapl pengaruh pH (3–6), suhu (40°C–80°C), dan waktu penyimpanan selama 5 hari. Penelitianl ini menggunakanl metode eksperimen laboratorium melalui prosesl ekstraksi sampel denganl metode lmaserasi, uji kadar antosianin, dan uji stabilitas ekstrak. Hasill penelitian menunjukkanl bahwa ekstrakl etanol l70% bunga kiacret memperoleh nilail rendemen 42,02%, dan kadar antosianin 8,908 mg/L, sedangkan ekstrak etanol 96% bunga kiacret memperoleh rendemen 35,72%, dan kadar antosianin 10,949 mg/L. Ekstrak bunga kiacret stabil pada pH 3–4, suhul 40°C, danl penyimpanan selamal satu lhari. Hasill stabilitas terbaik diperoleh pada ekstraksi bunga kiacret dengan pelarut etanol 96% yang dapat dilihat pada absorbansi tiap perlakuan yang diperoleh lebih tinggi dibandingkan dengan pelarut etanol 70%.
Co-Authors Agus Setiawaty Almeida, Maria Andi Tenri Kawareng Arifian, Hanggara Arifuddin, M Arifuddin, Muhammad Arsya, Dinara Eza Syahadati Asia, Nazha Delmora Asriani Baso Didik Hikmawan Bone, Mahfuzun Brigita, Vista Candrakanti, Bratandari Hana Farah, Harra Ismi Febrina, Lizma Filicia, Harfenas Althea Galih Rahmadana, Adly Harianti, Chita Herman Herman Hikmawan, Baso Didik Ibrahim, Arsyik ISWAHYUDI ISWAHYUDI Joshevine, Imelda Junaidin, Junaidin Laode Rijai Lestari, Seftya Ayu M. Arifuddin, M. Muhammad Faisal Mus, Nurul Muhlisa Nur, Yuspian Nurul Hasanah Prabowo, Wisnu Cahyo Pratiwi Putri, Bella Puspitawati, Ni Komang Anika Putri Sulistian, Salwah Rahmadani, Dessi Ridhotulloh, Yusuf Isro Rijai, Hifdzur Rashif Rija’i, Hifdzur Rashif RIKI RIKI, RIKI Rolan Rusli Rusli, Rolan Rusman, Arman Samsul, Erwin Sari, Karin Sopiya Sugeng, Santoso Supriatno Yusniah, Andi Zahrah, Nabila