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All Journal Indonesian Journal of Chemistry Jurnal Ilmu Kefarmasian Indonesia Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat Proceeding of Mulawarman Pharmaceuticals Conferences AMMA : Jurnal Pengabdian Masyarakat ANDIL Mulawarman Journal of Community Engagement Journal of Pharmaceuticals and Natural Sciences al Kimiya : Jurnal Ilmu Kimia dan Terapan Jurnal Sains dan Kesehatan Jurnal Abdita Naturafarm Jurnal Riseta Naturafarm Jurnal Riseta Soshum
Baso Didik Hikmawan
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Optimalisasi Produksi Fikosianin pada Sianobakteria Laut BTM 11 dan Uji Aktivitas Antioksidannya Baso Didik Hikmawan; Swastika Praharyawan; Kintoko Kintoko
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 2 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i2.1198

Abstract

Phycocyanin (PC)-producing cyanobacteria has shown many pharmaceutical applications, the main one is the antioxidant properties. Biosynthesis of PC-producing cyanobacteria is affected by many factors like nitrogen availability and light intensity during cultivation. This study aims to analyze the optimum concentration of nitrogen and light intensity during the cultivation of PC biosynthesis of marine cyanobacteria BTM 11 and identify its antioxidant properties This study was an experimental laboratory method and the PC level was determined through the variation of sodium nitrate (NaNO3) as a source of nitrogen dissolved in media and using different light intensities. The most optimum nitrogen and light intensity values of PC were measured by its antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical capture method. Data was analyzed by one-way ANOVA and the post-hoc Duncan to see whether p<0.05. The result showed that there was a significant difference in the PC level that was cultivated with the variation of NaNO3 concentrations. The highest PC level was observed in media containing 525 mg of NaNO3 and the optimum light intensity of 4500 lux. The result of the antioxidant activity assay showed that the BTM11’s PC’s antioxidant activity had its IC50 at 91.89 μg/mL and the IC50 of ascorbic acid was 2.39 μg/mL
Penyuluhan Pemanfaatan Limbah Kulit Buah Nanas Sebagai Alternatif Pembuatan Sabun Cuci Piring Di Kelurahan Bukit Pinang, Samarinda, Kalimantan Timur Muhammad Nuzul Azhim Ash Siddiq; Baso Didik Hikmawan; Hajrah; Noviyanty Indjar Gama; Nur Masyitah Zamruddin; Akhmad Jaizzur Rijai; Viriyanata Wijaya
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 9 : Oktober (2023): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Domestic waste is a global problem that is growing along with population growth and changes in consumption patterns. Domestic waste, if not handled properly, can cause environmental and health problems. Pineapple peel as a type of domestic waste has the potential to be used as an alternative pharmaceutical product because it still contains compounds in it, such as enzymes and bioactive compounds. Utilizing this waste not only reduces negative impacts on the environment, but also creates high-value products that are beneficial to society. Utilizing pineapple peel waste as a dishwashing soap product is the focus of our community service. The use of fruit peel waste represents a progressive step towards sustainability, small-scale home industry innovation and waste reduction which are increasingly important in efforts to preserve the environment and create products that are more beneficial to humans.
Formulasi Sediaan Sabun Cair Ekstrak Etanol Daun Afrika (Vernonia Amygdalina Delile) dan Aktivitas Antibakterinya: Formulation of Liquid Soap with Ethanol Extract from African Leaves (Vernonia Amygdalina Delile) and Its Antibacterial Activity Ervina Irmaya Sagita; Baso Didik Hikmawan; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 18 (2023): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v18i1.704

Abstract

Empirically, African leaves (Vernonia amygdalina delile) have been widely used by Indonesians as medicinal plants, especially for diseases caused by bacteria. Liquid soap is a soap that has a liquid form that produces more foam than solid soap so it is more attractive. This study aims to make the benefits of African leaves can be easily applied, so it is formulated in the form of liquid soap that meets the standards and also has an antibacterial effect. This research uses laboratory experimental qualitative and quantitative methods. The extract was obtained by maceration of simplisia with 96% ethanol, then variating the extract concentration to 5%, 10%, and 20% in the formula. The base formula is variating concentration of VCO, which are 20%, 25%, and 30%. The results showed that base formula 1 (F1) with 5% extract concentration had optimum characteristics, organoleptic test results of dark green color, liquid form that has a distinctive peppermint fragrance, pH value of 10.80, viscosity of 19 dpa.s, density of 1.086 g/mL, water content of 29.5%, foam stability of 95.56%, and free fatty acid content of 0.33%. Antibacterial test results against Staphylococcus aureus and Escerichia coli showed inhibition diameters of 23.8 mm and 25 mm respectively. Keywords: African leaves, Liquid soap, Antibacterial Abstrak Secara empiris daun afrika (Vernonia amygdalina delile) telah banyak digunakan oleh masyarakat Indonesia sebagai tumbuhan obat, salah satunya penyakit yang disebabkan oleh bakteri. Sabun cair merupakan sabun yang memiliki bentuk cairan menghasilkan busa lebih banyak daripada sabun padat sehingga lebih menarik. Penelitian ini, memiliki tujuan untuk membuat kemanfaatan daun afrika tersebut dapat dengan mudah untuk diaplikasikan, sehingga diformulasikan dalam bentuk sabun cair yang memenuhi standar juga memiliki efek antibakteri. Penelitian ini menggunakan metode kualitatif dan kuantitatif eksperimental laboratorium. Ekstrak didapatkan dengan maserasi simplisia dengan etanol 96%, lalu dibuat variasi konsentrasi 5%, 10%, dan 20% dalam sediaan. Basis formula dibuat dengan memvariasikan konsentrasi VCO yaitu 20%, 25%, dan 30%. Hasil penelitian menunjukkan bahwa formula basis 1 (F1) dengan konsentrasi ekstrak 5% memiliki karakteristik optimum, hasil uji organoleptik warna hijau tua, berbentuk cairan yang memiliki wangi khas peppermint, nilai pH 10,80, viskositas 19 dpa.s, bobot jenis 1,086 g/mL, kadar air 29,5%, stabilitas busa 95,56%, dan kadar asam lemak bebas 0,33%. Hasil uji antibakteri terhadap Staphylococcus aureus dan Escerichia coli menunjukkan diameter daya hambat sebesar 23,8 mm dan 25 mm berturut-turut. Kata Kunci: Daun Afrika, Sabun cair, Antibakteri
Edukasi Makanan Sehat Balita Sebagai Pencegahan Stunting di Desa Wonosari, Kabupaten Penajam Paser Utara, Kalimantan Timur Muhammad Nuzul Azhim Ash Siddiq; Hajrah Hajrah; Noviyanty Indjar Gama; Baso Didik Hikmawan; Viriyanata Wijaya; Nur Masyithah Zamruddin; Hamdani Hamdani; Rizka Dhilla Dwi Pangesti; Adithya Rizky Irawan
Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 4 No 2 (2023): Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Lembaga Peneliian dan Pengabdian Masyarakat (LPPM) Universitas Islam Madura (UIM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31102/darmabakti.2023.4.2.239-245

Abstract

Providing healthy food education for toddlers is one of the efforts in overcoming the problem of stunting. Providing education, counseling, and behavior change is included in the form of sensitive nutrition interventions, namely increasing awareness of parenting and nutrition for toddlers. The community service activity aims to increase the nutritional knowledge of mothers of toddlers on healthy and nutritious foods for toddlers and determine the relationship with the incidence of stunting. The methods used in this activity are lecturers delivering educational content directly to mothers of toddlers with the aid of visual media in the form of PowerPoint presentations. Pre and post-test questionnaires were given before and after education to measure the nutritional knowledge of mothers of toddlers. The nutritional knowledge scores obtained were statistically analyzed using Paired T-Test. The results of statistical analysis showed that there was a significant increase (p<0.05) in the mothers' knowledge scores before and after education. The service team also provided several examples of healthy foods for toddlers, especially complementary foods that are easy to make as an alternative to feeding children under five.
Naphthalene Derivates from Bawang Tiwai Bulb Eleutherine Bulbosa in Borneo Salam, Supriatno; Hikmawan, Baso Didik; Samsul, Erwin; Herman, Herman; Ahmad, Islamudin; Rijai, Laode; Nafiah, Mohd Azlan
al Kimiya: Jurnal Ilmu Kimia dan Terapan Vol 11, No 1 (2024): al Kimiya: Jurnal Ilmu Kimia dan Terapan
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ak.v11i1.35515

Abstract

Naphthalene derivative compounds named Eleutherol (1) and Eleutherol C (2) have been isolated from Bawang Tiwai Bulb Eleutherine bulbosa. We tested its cytotoxic activity against T47D breast cancer cells in vitro after isolating compounds 1 and 2 from the EtOH extract using conventional chromatography methods. Their chemical structures were elucidated based on spectroscopic analysis, including IR, HR-TOFMS, 1D, and 2D NMR, and by comparison to those related spectra previously reported. Compounds 1 and 2 were tested for their cytotoxic effects against T47D breast cancer cells and showed moderate cytotoxicity against T47D breast cancer cells with IC50 values of 117.15 and 80.21 µM, respectively, compared with cisplatin 24.07 µM.
Sosialisasi Digital Parenting: Pendekatan Orang Tua dalam Mendidik Anak di Era Digital Gusti Dimas Novarossi; Nina Damayanti; Hairunnisa; Najwa Jembar Aulya Rabbani; Mia Afpriana; Resti Safitri Yanti; Rina Emilia; Arya Bhima Andika; Abdul Razak Maulana; Andi Muhammad Alfian Malindo; Muhammad Fachrul Ilmi; Baso Didik Hikmawan; Junaidin; Islamudin Ahmad
Jurnal Abdita Naturafarm Vol. 1 No. 2 (2024): J. Abdita Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jan.v1i2.3846

Abstract

The era of digitalization gives complete freedom to individuals, both parents and children, especially regarding access to all the information disseminated on social media. Of course, the number of gadgets is increasing among children, which has positive and negative effects. Therefore, this service activity aims to socialize digital parenting as a parental strategy to educate their children to use gadgets in a more targeted and time-bound way to reduce the negative impact of gadget use among children. The approach that will be taken is to provide learning or knowledge about the importance of understanding digital education, having the ability to use mobile phones, being critical of the media, and giving understanding through good delivery. At Mulawarman University's community service activities in Jenebora Village with the Digital Parenting Socialisation Work Programme, we delivered educational material about the importance of parents in educating children in today's digital age, which both parents and children attended. It is hoped that through this socialization, parents will increase their supervision of their children. Parents also hoped that this socialization in educating children in the digital era would be the first step in avoiding the harmful effects of mobile phone use on children.
Pembelajaran Interaktif dan Menyenangkan di Luar Lingkungan Sekolah Melalui Bimbingan Belajar Harian Wilda Azizah; Devina Yasintha Nayaputri; Nur Qurratul Nabila; Arina Hasya Sabila; Ailsa Purwabhagawanta Saskirana Laksono; Devona Valerie Simatupang; Baso Didik Hikmawan; Junaidin Junaidin; Islamudin Ahmad
Jurnal Abdita Naturafarm Vol. 1 No. 2 (2024): J. Abdita Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jan.v1i2.4753

Abstract

This study evaluated the effectiveness of a daily home-based learning program implemented in Rumah Pintar, Pantai Lango. The program aimed to improve the academic skills of children aged 3-12 years who were experiencing learning difficulties. The intervention, conducted from July 12 to August 2, 2024, provided a structured learning environment outside of school hours. Participants were divided into groups based on their academic levels, addressing needs ranging from basic literacy and numeracy to English language learning. Results indicated that the program was successful in enhancing participants' abilities in reading, writing, and mathematics. However, challenges such as fluctuating daily attendance, attributed to a lack of parental awareness about the importance of home learning, were encountered. Despite these challenges, the program demonstrated the potential of non-formal, home-based learning initiatives in addressing the educational needs of children in underserved areas.
Metabolit Sekunder dan Uji Bioaktivitas Sitotoksik Ekstrak Buah Sumpit (Brucea javanica (L.) Merr) terhadap Artemia salina Leach Tajuddin Nur; Arman Rusman; Baso Didik Hikmawan; Maria Almaida; Herman; Arsyik Ibrahim
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/368zcy93

Abstract

Research carried out with the title of Secondary Metabolite Identification and bioactivity Fruit Extract Sumpit (Brucea javanica (L) Merr) to the shrimp larvae Artemia salina Leach. This study aims to identifying classes of secondary metabolites as well as test the bioactivity of secondary metabolites sumpit. Identifikasi fruit extracts performed to test the Chopsticks fruit extracts and fractions against reagent, while the bioactivity test was conducted using Brine Shrimp Lethality Test (BSLT). Data were analyzed using the method of Reed and Muench to get Lethality Concrentation value 50% (LC50). The results showed that the fruit extract Sumpit contain the alkaloid class of secondary metabolites, karatenoid, saponins, tannins, phenolic compounds, steroids, and terpenoids. Sumpit fruit bioactivity test results had LC50 values of the methanol extract of 3.10 ppm, n-hexane fraction of 2.09 ppm, 0.79 ppm ethyl acetate fraction and n-butanol fractions of 0.74 ppm.
Pengaruh Konsumsi Produk Tanaman Biofarmasi Dalam Kemasan Dan Konsumsi Langsung Terhadap Manfaat Kesehatan Dan Manfaat Ekonomi, Serta Loyalitas Konsumen Junaidin Junaidin; Baso Didik Hikmawan; Hifdzur Rashif Rija'i; Arman Rusman
Jurnal Riseta Soshum Vol. 1 No. 2 (2024): J Riseta Soshum
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrs.v1i2.6167

Abstract

Mengkonsumsi tanaman biofarmasi baik dalam bentuk kemasan atau mengkonsumsi secara langsung dari tanaman biofarmasi, ternyata menunjukkan  persepsi yang berbeda dalam hal manfaat kesehatan, manfaat ekonomi, dan loyalitas konsumen. Studi ini menggunakan Model Persamaan Struktural (SEM), dan menganalisis 301 responden. Hasil analisis membuktikan bahwa: Tidak ada pengaruh signifikan antara hubungan antara konsumsi tanaman biofarmasi yang dikemas terhadap manfaat kesehatan dan manfaat ekonomi, serta loyalitas konsumen. Terdapat hubungan yang signifikan antara konsumsi langsung tanaman biofarmasi terhadap manfaat kesehatan, manfaat ekonomi, dan loyalitas konsumen; Terdapat hubungan signifikan antara manfaat kesehatan dan manfaat ekonomi terhadap loyalitas konsumen. Hasil analisis juga membuktikan bahwa budaya masyarakat yang terbiasa mengonsumsi tanaman biofarmasi terbukti secara empiris.
Pharmacognosic Study and Determination of Marker Compounds Soursop Leaves (Annona muricata) M. Arifuddin; Muhammad Faisal; Erwin Samsul; Baso Didik Hikmawan; Wisnu Prabowo; Islamudin Ahmad; Arsyik Ibrahim
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 1 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/zjthbv92

Abstract

Soursop (Annona muricata) is reported to have great efficacy in traditional medicine in Indonesia so it is very vulnerable to being faked or sold as low quality. Apart from having a delicious fruit taste, Soursop leaves have also been used as an effective cancer medicine by the public and have been scientifically proven so that Soursop can be used as a phytopharmaceutical product. Therefore, it is necessary to carry out research to determine pharmacognosy parameters and marker compounds as ingredients needed to obtain the authenticity of simplicia and plant extracts. This research includes macroscopic and microscopic examination of leaves, macroscopic and microscopic examination of simplicia, fluorescence characteristics of simplicia, determining the solubility of methanol extract in various non-polar and polar solvents as well as the characteristics of marker compounds that can be used as alternatives to existing marker compounds from Soursop (Annona muricata). The research results obtained are important information as a stage for the identification and standardization of soursop leaves (Annona muricata) as a raw material for herbal medicine.
Co-Authors Abdul Razak Maulana Adithya Rizky Irawan Ailsa Purwabhagawanta Saskirana Laksono Akhmad Jaizzur Rijai Almeida, Maria Andi Muhammad Alfian Malindo Arief Wicaksono Nur Qowiyyu Arifian, Hanggara Arifuddin, Muhammad Arina Hasya Sabila Arsyik Ibrahim Arsyik Ibrahim Arya Bhima Andika Bone, Mahfuzun Chairani Sintya Devina Yasintha Nayaputri Devona Valerie Simatupang Ervina Irmaya Sagita Erwin Samsul Febrina, Lizma Gusti Dimas Novarossi Hairunnisa Hajrah Hajrah Hajrah Hamdani Hamdani Herman Herman Hifdzur Rashif Rija'i Ibrahim, Arsyik Islamudin Ahmad Islamudin Ahmad Islamudin Ahmad Junaidin Junaidin Junaidin, Junaidin Kintoko, Kintoko Laode Rijai M. Arifuddin M. Arifuddin, M. Mia Afpriana Mohd Azlan Nafiah, Mohd Azlan Muhammad Fachrul Ilmi Muhammad Faisal Muhammad Faisal Muhammad Nuzul Azhim Ash Siddiq Mus, Nurul Muhlisa Najwa Jembar Aulya Rabbani Nina Damayanti Noviyanty Indjar Gama Nur Masyitah Zamruddin Nur Masyitah Zamruddin Nur Qurratul Nabila Resti Safitri Yanti Ridhotulloh, Yusuf Isro Rija'i, Hifdzur Rashif Rijai, Hifdzur Rashif Riki RIKI RIKI, RIKI Rina Emilia Rizka Dhilla Dwi Pangesti Rolan Rusli Rusman, Arman Salam, Supriatno Samsul, Erwin Sugeng, Santoso Supriatno Salam Swastika Praharyawan Tajuddin Nur Viriyanata Wijaya Viriyanata Wijaya Wilda Azizah Wisnu Prabowo