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Journal : INDONESIAN JOURNAL OF PHARMACY

The influence of mfp-implant on tissue pertinent changes of wistar rattus-rattus ., Widjijono
Indonesian Journal of Pharmacy Vol 21 No 1, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.78 KB) | DOI: 10.14499/indonesianjpharm0iss0pp48-53

Abstract

Fluoride  for  caries  prevention  if  consumes  for  a  long  period,  it  is sometimes  made  bored.  Normally, fluoride intake is uncontrolled and cause fluorosis.  Alternatively, implant fluor becomes the controlled method.  The study was  aimed  to  determine  the  influence  of  MFP-implant  on  tissue  pertinent changes  of  Wistar  Rattus-rattus.  The research subjects were Rattus-rattus mother of 20 rats (2 days pregnant).  Twenty  rats  were  divided  into  4  groups, namely  control  (K),  implant  P1,  implant  P2  and  implant  P3.  Subcutaneous implantation was done on rat back.  On the 8th day, euthanasia was done. Excission  was  done  surround  the  implant  tissue,  then  blocked  and  fixed  by formalin  buffer.  The specimen was cut along the implant tissue were examined by light microscope.  The data were analyzed by descriptive statistic.  The result showed that the incision was cured on the 5th – 7th day.  Tissue pertinent changes determination showed that there was lipid cell infiltration and relatively thicker of tissue on implant P3 and.  There was not any inflammation cell infiltrated and fibrous tissue. In conclusion, the infiltration of lipid cell on implant P3. The implant P2 was fulfilled the requirement of implant devices.Key words: MFP-implant, pertinent changes, rat
The influence of mfp-implant on tissue pertinent changes of wistar rattus-rattus Widjijono Widjijono
Indonesian Journal of Pharmacy Vol 21 No 1, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1161.216 KB) | DOI: 10.14499/indonesianjpharm0iss0pp46-51

Abstract

Fluoride for caries prevention if consumes for a long period, it is sometimes made bored. Normally, fluoride intake is uncontrolled and cause fluorosis. Alternatively, implant fluor becomes the controlled method. Te study was aimed to determine the influence of MFP-implant on tissue pertinent changes of Wistar Rattus-rattus. The research subjects were Rattus-rattus mother of 20 rats (2 days pregnant). Twenty rats were divided into 4 groups, namely control (K), implant P1, implant P2 and implant P3. Subcutaneous implantation was done on rat back. On the 8th day, euthanasia was done. Excission was done surround the implant tissue, then blocked and fixed by formalin buffer. The specimen was cut along the implant tissue were examined by light microscope. The data were analyzed by descriptive statistic. The result showed that the incision was cured on the 5th – 7th day. Tissue pertinent changes determination showed that there was lipid cell infiltration and relatively thicker of tissue on implant P3 and. there was not any inflammation cell infiltrated and fibrous tissue. In conclusion, the infiltration of lipid cell on implant P3. The implant P2 was fulfilled the requirement of implant devices.Key words : MFP-implant, pertinent changes, rat