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All Journal Althea Medical Journal Journal of Dentistry Indonesia Jurnal Administrasi Kesehatan Indonesia Global Medical and Health Communication JURNAL PENDIDIKAN KEPERAWATAN INDONESIA Dental Journal (Majalah Kedokteran Gigi) Jurnal Sistem Kesehatan Padjadjaran Journal of Dentistry Narra J Jurnal Penyakit Dalam Indonesia

Rudi Wisaksana

Department Of Internal Medicine, Faculty Of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung

Author-ID : 419224

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 22 Documents Claim Missing Document

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Knowledge, Attitude, and Behavior Regarding Homosexualilty among New Students in Universitas Padjadjaran Ade Nea; Rudi Wisaksana; Enny Rohmawaty
Althea Medical Journal Vol 5, No 4 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Homosexualilty has raised a controversy in the society, which commonly has a negative attitude towards homosexual. It is important to develop knowledge and attitude about homosexuality in new students as agents of change. This study aimed to identify the knowledge, attitude, and behavior of new undergraduate students in Universitas Padjadjaran about homosexual.Methods: This was a descriptive quantitative cross-sectional study using primary data obtained from questionnaires, distributed not randomly to new undergraduate students of 2016/2017 academic year in Universitas Padjadjaran (n=122) from October to November 2016. Questions asked were demographic data, knowledge and attitude towards homosexualilty, and homosexual behavior.Results: Respondents had a good knowledge (18%; n=22), average (66.4%; n=81) and low knowledge (15.6%; n=19) about homosexuality and the majority (55.7%; n=68) of respondents had a negative attitude towards homosexuality. A heterosexual behavior had been showed in 92.6% (n=113) respondents, and 7.4% (n=9) had a heterosexual dominant behavior.Conclusions: In our new undergraduate students’ community, the majority has average knowledge, however, with a negative attitude towards about homosexuality. The role of new students as agents of change is to educate the community to prevent potential health issues. The developing of knowledge, attitude, and behavior towards homosexual through a holistic education from health workers should be promoted.

Implementation of Youth Information and Counseling Centers Related to HIV/AIDS Prevention in a Junior High School in Bandung Shifa Nadya Rahma; Insi Farisa Desy Arya; Rudi Wisaksana
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2252

Background: Adolescents are the population group most at risk of HIV infection due to low knowledge about HIV/AIDS. The National Population and Family Planning Board (Badan Kependudukan dan Keluarga Berencana Nasional, BKKBN) has developed the Youth Information and Counseling Center (Pusat Informasi dan Konseling Remaja, PIK-R) Program as a forum for information and counseling services, one of which is about Adolescent Reproductive Health (ARH) including HIV/AIDS. This study aimed to explore whether the implementation of the programs related to HIV/AIDS prevention in adolescents, specifically in junior high school in Bandung City.Methods: A qualitative descriptive study was carried out at a junior high school in Bandung in August 2018. This study used a purposive sampling technique and data were collected by conducting in-depth interviews with nine program administrators who were then transcribed and coded based on the PIK-R management guidelines using the NVIVO12 software, observing the program activities and documentations study which were then triangulated.Results: Several indicators in the growing stage had been implemented according to the guidelines, consisting of mastering ARH education materials including HIV/AIDS, conducting activities in the form of providing materials and peer counseling although without a secretariat room, and establishing networks and partnerships.Conclusion: The PIK-R program can be a media for preventing HIV/AIDS among junior high school students in Bandung regardless of resource limitations. Therefore, supports from BKKBN and the school itself is needed to improve the implementation of this program.

Analysis of the relationship between human cytomegalovirus DNA and gB-1 genotype in the saliva of HIV/AIDS patients with xerostomia and salivary flow rate Irna Sufiawati; S. Suniti; Revi Nelonda; Rudi Wisaksana; Agnes Rengga Rendati; Riezki Amalia; Isabellina Dwades Tampubolon
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 4 (2019): December 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v52.i4.p197-203

Background: Human immunodeficiency virus (HIV) infection increases vulnerability to opportunistic viral infection, including Human cytomegalovirus (HCMV) infection, that has been detected in saliva. The HCMV envelope glycoprotein B (gB) is highly immunogenic and has been associated with HCMV-related diseases. Purpose: The purpose of this study is to assess the prevalence of HCMV and gB-1 genotype in the saliva of HIV/AIDS patients and to analyse their relationship with xerostomia and salivary flow rate (SFR). Methods: This cross-sectional study involved 34 HIV/AIDS patients. Saliva was tested for the presence of HCMV DNA using PCR microarrays, and nested PCR for gB-1 genotype detection. Xerostomia was measured using a Fox’s questionnaire. Unstimulated whole saliva flow rate was measured by means of the spitting method. Results: The composition of the research population consisting of 73.5% males and 26.5% females with HIV/AIDS. HCMV was found in 64.7% of HIV/AIDS patients, while gB-1 genotype was detected in 59.1%. Xerostomia was closely associated with the presence of HCMV in saliva (p<0.05), but not with gB-1. There was no significant relationship between xerostomia and SFR rates in the research subjects with HCMV positive saliva (p> 0.05). Conclusion: The presence of xerostomia-associated HCMV in saliva was elevated among HIV/AIDS patients. Further investigation is required to identify other gB genotypes that may be responsible for xerostomia and SFR changes in HIV/AIDS patients.

Gambaran Efek Samping dan Kepatuhan Terapi Antiretroviral pada Pasien HIV di Rumah Sakit Dr. Hasan Sadikin Bandung tahun 2015 Dewi Puspasari; Rudi Wisaksana; Rovina Rovina
Jurnal Sistem Kesehatan Vol 3, No 4 (2018): Volume 3 Nomor 4 Juni 2018
Publisher : Universitas Padjadjaran

Jawa Barat berada dalam posisi 4 besar jumlah kasus baru infeksi HIV terbanyak di Indonesia selama 2012-2014. Pengidap HIV memerlukan terapi Antiretroviral (ARV) agar perkembangan penyakit, komplikasi dan penularannya dapat dicegah. Penelitian ini bertujuan untuk mengetahui gambaran efek samping dan kepatuhan terapi antiretroviral pada pasien HIV berbagai stadium. Penelitian ini merupakan penelitian deskriptif kuantitatif yang dilaksanakan pada September-November 2016. Data sekunder diambil secara restropektif dari 201 rekam medik (total sampling) pasien HIV baru di Klinik Teratai RSUP Dr. Hasan Sadikin periode Januari - Desember 2015. Hasil menunjukkan persentase stadium pasien HIV yaitu stadium 4(41,8%), 1(25,4%), 3(24,9%) dan 2(7,9%). Kebanyakan pasien terdiagnosis dan/atau berobat ketika sakitnya sudah parah atau justru saat screening pada kelompok berisiko. Jumlah pasien yang mengalami efek samping ARV lebih banyak (50,7%) dibanding yang tidak. Efek samping yang paling banyak muncul diantaranya mual, pusing, gatal dan ruam kemerahan pada kulit. Efek samping yang timbul bergantung pada variabilitas kadar ARV dalam plasma. Persentase pasien yang patuh menjalani terapi ARV adalah 58,2%. Tingkat kepatuhan sangat dipengaruhi oleh pengetahuan dan keyakinan akan pentingnya pengobatan. Disimpulkan bahwa efek samping yang timbul bervariasi dan dialami oleh lebih banyak pasien, jumlah pasien patuh menjalani terapi antiretroviral lebih dari setengah total jumlah pasien.Kata kunci: Antiretroviral, Efek samping, Kepatuhan, Pasien HIV, Stadium klinis.

Pengetahuan, Sikap, dan Praktik pada Guru SMP Swasta Berbasis Agama Katolik di Kota Bandung terkait Pendidikan Kesehatan Reproduksi Sebagai Upaya Pencegahan HIV/AIDS Hestia Nur Annisa; Rudi Wisaksana; Nita Arisanti
Jurnal Sistem Kesehatan Vol 4, No 2 (2018): Volume 4 Nomor 2 Desember 2018
Publisher : Universitas Padjadjaran

Penderita terbanyak HIV di Indonesia berusia 20-29 tahun, dengan lama masa inkubasi, maka pertama kali terpapar virus HIV usia 10-19 tahun. Sebelum melakukan intervensi, lebih baik dilakukan survey terlebih dahulu kepada guru. Penelitian bertujuan untuk mengetahui gambaran pengetahuan, sikap, dan praktik guru SMP swasta berbasis Agama Katolik di Kota Bandung terkait pendidikan kesehatan reproduksi. Penelitian menggunakan metode deskriptif dengan pendekatan cross sectional. Penentuan jumlah sampel pada penelitian secara total sampling dilakukan pada bulan Februari-Juni 2017 di SMP swasta berbasis agama Katolik di Kota Bandung. Sampel penelitian melibatkan seluruh guru. Kriteria Inklusi penelitian adalah guru dengan minimal mengajar 1 tahun, dan kriteria eksklusi berupa guru yang tidak hadir dan/atau tidak bersedia menjadi responden saat pengambilan data. Penelitian ini dilakukan terhadap 98 responden. Pengetahuan guru SMP Swasta berbasis agama katolik di Kota Bandung terkait pendidikan reproduksi (100%) tergolong baik, sikap (100%) tergolong positif, dan praktik guru 87% pernah melakukan pendidikan kesehatan reproduksi. Berdasarkan hasil dan pembahasan maka dapat disimpulkan bahwa pengetahuan dan sikap guru sudah baik. Pada aspek praktik, hampir semua guru telah melakukan pendidikan kesehatan reproduksi. Beberapa guru yang belum pernah melakukan pendidikan kesehatan reproduksi dapat dipengaruhi oleh perbedaan kewajiban mata pelajaran yang diajarkan.Kata Kunci: HIV/AIDS, Kesehatan Reproduksi, Pengetahuan, Praktik, Sikap

Exploration of Methadone and HIV Treatment for Injecting Drug Users in West Java, Indonesia: Lessons from Practice Igor van Laere; Teddy Hidayat; Rudi Wisaksana
Global Medical & Health Communication (GMHC) Vol 1, No 1 (2013)
Publisher : Universitas Islam Bandung

Over the last decade, Indonesia became one of the fastest growing injecting drug user (IDU) driven HIV epidemics in Asia. Among strategies to prevent and control the HIV epidemic in Indonesia, methadone maintenance treatment (MMT) has been established and could become an entry point for HIV testing and treatment in IDUs. This study explored MMT and HIV treatment practices in West Java. An evaluation team visited six MMT clinics, interviewed staff and collected data on patient characteristics, methadone dose, and HIV testing and treatment practices. By October 2011, from 203 IDUs entering MMT (range 7–73 per clinic), 95% were male with the average age of 31 years (range 19–60 years), 92% had a senior high school or higher diploma, 47% had a regular income, and 55% were married. The mean methadone dose was 79 mg/day (range 13–208 mg/day). About 85% of the MMT patients were tested for HIV, of whom 70% were found HIV positive (121/173), while 59% had a baseline CD4 count >200 cells/mm3 and 65% were receiving ART. In conclusion, few IDUs entered MMT in West Java and among those who did; high HIV and ART rates were reported, stressing the need for active linking between harm reduction services and integrated MMT and HIV treatment for IDUs.

Nilai Mean Corpuscular Volume (MCV) Sebagai Petunjuk Ketaatan Minum Obat pada Penderita HIV Rudolf Andean Manullang; Rudi Wisaksana; Rachmat Sumantri
Global Medical & Health Communication (GMHC) Vol 1, No 1 (2013)
Publisher : Universitas Islam Bandung

Pengobatan antiretroviral (ARV) pada penderita HIV mengubah secara dramatis prognosis penderita HIV tetapi memerlukan ketaatan pengobatan yang sempurna. Hingga saat ini penilaian ketaatan pengobatan ARV merupakan hal yang sulit dikerjakan karena ketiadaan metode penilaian yang ideal tetapi dapat digunakan sehari-hari di klinik. Pada penderita HIV yang mendapat pengobatan ARV, evaluasi ketaatan minum obat ARV sangat penting. Ketidaktaatan minum obat pada penderita HIV memberikan konsekuensi yang beragam, seperti kegagalan pengobatan, resistensi obat, dan terbentuk strain virus baru. Kegagalan pengobatan yang terjadi akan menimbulkan efek besar terhadap penderita dan keluarganya dari segi ekonomi maupun sosial mengingat sebagian besar penderita HIV adalah pria usia produktif. Evaluasi ketaatan minum obat dengan optimal lebih baik dibandingkan dengan menunggu terjadi kegagalan virologis. Nilai mean corpuscular volume (MCV) merupakan parameter hematologis yang sederhana dan dapat membantu proses evaluasi ketaatan minum obat. Perlu diperhatikan pada penderita HIV yang mendapat obat zidovudin atau stavudin, tidak terdapat makrositosis sebelum pengobatan, dan keadaan medis atau obat lain yang dikonsumsi penderita yang berpengaruh pada nilai MCV. Pemeriksaan viral load, CD4, dan keadaan klinis penderita tetap merupakan parameter utama yang harus digunakan dalam menilai respons pengobatan di sarana yang memadai. MEAN CORPUSCULAR VOLUME (MCV) AS AN ASSESSMENT OF ADHERENCE TO ANTI RETROVIRAL TREATMENT IN HIV PATIENTSAnti retroviral (ARV) in HIV patients dramatically changed the prognosis of patients with HIV but requires perfect adherence to treatment. Until now the assessment of adherence to ARV treatment is difficult because ideal method of assessment to use in day-to-day practice is unavailable. Adherence to treatment for HIV patients receiving ARV is very important since the inconstancy resulted in in several problem such as treatment failure, drug resistance, and development of new virus strain. Treatment failure will resulted in magnitude effect both for the patients and family since patients usually are productive age males. To evaluate treatment adherence is much better than waiting for virology failure. Mean corpuscular volume (MCV) value is a basic hematology parameter that can be used to evaluate the process of treatment adherence. The use of this parameter needed to take into account patients with zidovudine or stavudine treatment, ensure there is no macrocytosis before treatment and other medical status or drug consumed which can contribute to MCV value. Viral load, CD4, and patients clinical status still become the main parameter to be used to evaluate treatment responses on HIV patients in adequade facilities.

Korelasi Jumlah CD4 dan Total Lymphocyte Count (TLC) pada Penderita HIV/AIDS dengan dan tanpa Terapi Antiretroviral Ivana Agnes Sulianto; Agnes R. Indrati; Rudi Wisaksana; Noormartany Noormartany
Global Medical & Health Communication (GMHC) Vol 1, No 1 (2013)
Publisher : Universitas Islam Bandung

Jumlah CD4 merupakan parameter laboratorium yang digunakan untuk memulai dan memantau terapi antiretroviral (ART) pada penderita HIV/AIDS. Pemeriksaan jumlah CD4 membutuhkan peralatan laboratorium yang mahal dan tenaga terlatih. World Health Organization (WHO) merekomendasikan total lymphocyte count (TLC) sebagai pengganti CD4 dalam memulai terapi. Penelitian ini bertujuan untuk melihat korelasi antara jumlah CD4 dan TLC pada data dasar, pemantauan pertama dan kedua penderita HIV/AIDS sebagai dasar digunakannya TLC untuk pemantauan terapi. Penelitian ini merupakan penelitian observasional analitik dan bagian dari penelitian kohort IMPACT (Integrated Management for Prevention And Care and Treatment of HIV/AIDS) pada pasien HIV/AIDS di RS Dr. Hasan Sadikin Bandung. Data tersebut dibagi menjadi kelompok tanpa ART dan dengan ART, masing-masing kelompok dibagi berdasarkan jenis kelamin. Analisis korelasi dilakukan pada data CD4 dan TLC dari tiap kelompok. Penelitian ini menggunakan 2.239 data. Korelasi antara CD4 dan TLC pada data dasar pria tanpa ART adalah 0,644 (p=0,01), wanita tanpa ART adalah 0,74 (p=0,01), pria dengan ART 0,67 adalah (p=0,01), wanita dengan ART adalah adalah 0,601 (p=0,01). Korelasi antara CD4 dan TLC pemantauan pertama pria tanpa ART 0,56 (p=0,01), wanita tanpa ART adalah 0,606 (p=0,01), pria dengan ART adalah 0,569 (p=0,01), wanita dengan ART adalah 0,466 (p=0,01). Korelasi antara CD4 dan TLC pemantauan kedua pria tanpa ART adalah 0,697 (p=0,01), wanita tanpa ART adalah 0,306 (p=0,01), pria dengan ART adalah 0,556 (p=0,01), wanita dengan ART adalah 0,561 (p=0,01). Simpulan, terdapat korelasi yang baik antara jumlah CD4 dan TLC, sehingga TLC dapat digunakan sebagai alternatif pemantauan terapi sebelum penderita melakukan pemeriksaan CD4. CORRELATION OF CD4 AND THE TOTAL NUMBER OF LYMPHOCYTE COUNT (TLC) IN HIV/AIDS PATIENTS WITH AND WITHOUT ANTIRETROVIRAL THERAPYCD4 count is a marker for initial and follow up antiretroviral therapy (ART) in HIV/AIDS patients. It requires expensive equipment and skill to performed. World Health Organization (WHO) recommends total lymphocyte count (TLC) as a substitute marker for CD4 count to start ART. The aim of this study is to evaluate the correlation between CD4 count and TLC in baseline and follow up data as a guide for follow up therapy. This study was an analytical observational study of HIV/AIDS patients data in Dr. Hasan Sadikin Hospital Bandung. It is part of IMPACT (Integrated Management for Prevention And Care and Treatment of HIV/AIDS) study. The sample of 2,239 was divided into non ART and ART groups. The data was analyzed using correlation analysis. The results showed that the correlation between CD4 and TLC at baseline in male without ART was 0.644 (p=0.01), female without ART was 0.74 (p=0.01), male with ART was 0.67 (p=0.01), and female with ART was 0.601 (p=0.01). The correlation between CD4 and TLC at first follow up in male without ART was 0.056 (p=0.01), female without ART was 606 (p=0.01), male with ART was 0.569 (p=0.01), female with ART was 0.466 (p=0.01). The correlation between CD4 and TLC at second follow up in male without ART was 0.697 (p=0.01), female without ART was 0.306 (p=0.01), male with ART was 0.556 (p=0.01), female with ART was 0.561 (p=0.01). In conclusion, there is a good correlation between CD4 count and TLC so that TLC can be used as an alternative marker for follow up therapy.

Angka Kejadian dan Karakteristik Klinis Pasien Infeksi Jamur Invasif di RSUP Dr. Hasan Sadikin Tahun 2020 – 2022 Alessandro, Ariella; Fauziah, Nisa; Megantara, Imam; Wisaksana, Rudi; Dewi, Intan Mauli Warma
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Introduction. Invasive fungal infection (IFI) is increasingly common in patients at risk, especially those with impaired immune response. In Indonesia, there is currently a low prevalence of IFI which may be influenced by challenges in diagnosis. This study aimed to determine the prevalence and clinical characteristics of IFI patients in Dr. Hasan Sadikin Hospital in Bandung, Indonesia. Methods. This cross-sectional study was conducted at Dr. Hasan Sadikin Hospital. Data were collected using medical records of IFI patients diagnosed between 2020 and 2022 which were selected using total sampling method. Demographic data, clinical symptoms, radiological appearance, and laboratory results were recorded. Results. The prevalence of IFI in Dr. Hasan Sadikin Hospital between 2020 and 2022 was 0,04% (40 per 100,000 patients). The most common cause of invasive fungal infection was Cryptococcus spp. and Candida spp. Fever and loss of consciousness were the two most common signs and symptoms found in this study. HIV/AIDS was present in 51,4% of cases. The diagnostic test was mostly done with cryptococcal antigen (CrAg) examination. Lung involvement was common, appearing as consolidation, infiltration, and ground glass opacity in the lungs. The mortality rate of IFI patients was 51,4%. Conclusions. The prevalence of IFI in Dr. Hasan Sadikin Hospital was quite low, with HIV/AIDS as the most common risk factor. However, there was a high mortality rate found this study is high. Thus, timely diagnosis and antifungal treatment induction should be considered to improve the outcome of invasive fungal infection patients.

THE COST OF SMS REMINDER TO IMPROVE ARV ADHERENCE AMONG KEY POPULATIONS Juwita, Mery Nurma; Donny Hardiawan; Prawinegara, Rozar; Handayani, Miasari; Wisaksana, Rudi; Januraga, Pande Putu; Sulaiman, Nurjannah; Siregar, Adiatma
Indonesian Journal of Health Administration (Jurnal Administrasi Kesehatan Indonesia) Vol. 12 No. 2 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jaki.v12i2.2024.238-249

Background: HATI is an implementation trial aimed at improving HIV care and treatment, including through SMS reminders. Aims: This study aimed to estimate the cost and analyze the outcomes of providing SMS Reminders within the HATI program in different settings. Methods: Data were analyzed using a micro-costing approach from providers' and health systems' perspectives. Subjects were divided into intervention and control groups for outcome analysis, with adherence as the outcome indicator. Results: From a provider's perspective, the highest cost was incurred in primary health care (PHC) clinics, while the lowest was in hospital clinics, most likely due to a much higher volume of SMS sent from hospitals. Costs from the health system perspective were more than two times higher than those from the provider perspective, as they included costs borne by HATI management and intervention setup. In one year, the number of patients with >95% adherent visits was higher in the intervention group than the control group, although visits decreased over time in both groups. The highest number of patients with >95% adherent visits was found in PHC clinics, while the lowest was in hospital clinics. Conclusion: SMS reminders can be expensive initially due to setup and program costs. However, they become cheaper once they are embedded into the existing system. Further studies are necessary to determine better site options for scaling up SMS reminder intervention and to study the declining adherence rate in all clinics. Keywords: Adherence, cost analysis, HIV, Indonesia, SMS reminder

Co-Authors Ade Nea Adiatma Siregar, Adiatma Adiatma YM. Siregar, Adiatma YM. Agnes R Indrati, Agnes R Agnes R. Indrati Agnes Rengga Rendati Agung Firmansyah Sumantri Agustinawaty, Hervina Alessandro, Ariella Ali Djumhana Amalia, Riezki Andreas Jonathan Arfianti Arfianti Bachti Alisjabana, Bachti Bony Wiem Lestari Bony Wiem Lestari, Bony Wiem Dewi Puspasari Dewi Puspasari Dewi, Intan Mauli Warma Djojosugito, Fauzia A. Dolvy Girawan Donny Hardiawan Enny Rohmawaty Fauziah, Nisa Guntur Darmawan Handayani, Miasari Hervina Agustinawaty Hestia Nur Annisa Ida Parwati Igor van Laere Igor van Laere, Igor van Imam Megantara Indrati, Agnes R. Inriyana, Ria Insi Farisa Desy Arya Irna Sufiawati Isabellina Dwades Tampubolon Ivana Agnes Sulianto Ivana Agnes Sulianto, Ivana Agnes Juniati, Rianita Juwita, Mery Nurma Khairunisa, Siti Q. Kusman Ibrahim Munthe, Eliza Kristina M Nasronudin Nasronudin Nataprawira, Heda M Nenny Agustanti Nita Arisanti Noormartany Pande Putu Januraga Pipit Pitriyan Prawinegara, Rozar Prayudi Santoso Rachman, Brian E. Rachmat Sumantri Rachmat Sumantri Revi Nelonda Riezki Amalia Rovina Ruslami, Rovina Rudolf Andean S. Suniti Shifa Nadya Rahma Siregar, Fajri M. Soeroto, Arto Y Sulaiman, Nurjannah Teddy Hidayat Teddy Hidayat Tenny Setiani Dewi Wahyu Hidayat Yovita Hartantri

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