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All Journal Jurnal Keperawatan Indonesia Timur (East Indonesian Nursing Journal) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Pengabdian Ilmu Kesehatan Jurnal Rumpun Ilmu Kesehatan Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan Usada Nusantara: Jurnal Kesehatan Tradisional Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Aulia Debby Pelu
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Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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UJI AKTIVITAS ANTIFUNGI EKSTRAK ANGGUR LAUT (Caulerpa sp.) ASAL PULAU GESER KABUPATEN SERAM BAGIAN TIMUR TERHADAP FUNGI Candida albicans Aulia Debby Pelu; Maryam Lihi; Moh. Nurul Iman Wokas
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 2 No. 2 (2022): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v2i2.1177

Abstract

Sea Grape (Caulerpa sp.) is a group of seaweed which is a macroalgae belonging to the Caulerpaceae family . Sea Grape very potential as a new antifungal drug because it contains secondary metabolites of saponins and flavonoids that can inhibit the growth of the fungus Candida albicans . The purpose of this study was to determine the content of secondary metabolites present in sea grapes and antifungal activity test of sea grapes (Caulerpa sp.) which was extracted using 70% ethanol as a solvent against the fungus Candida albicans. The antifungal activity was tested using the disc diffusion method with several concentrations of 5%, 10%, 25%, 50%, 85, 130%, 185%, and 250%, ketoconazole as a positive control and aquadest as a negative control. The results showed that the extraction of sea grapes contains secondary metabolites, namely: Saponins, Flavonoids, Tannins and Steroids capable of inhibiting the growth of the fungus Candida albicans, at a concentration of 25% with an inhibition zone diameter of 12.5 mm, 50% diameter of the inhibition zone 14.5 mm, 130% the diameter of the inhibition zone is 17.5 mm, 185% the diameter of the inhibition zone is 19 mm and 250% with the diameter of the inhibition zone is 22mm. The test results showed that the effective and very strong concentration of inhibiting the growth of Candida albicans was at a concentration of 250% with an inhibition zone of 22 mm.
Co-Authors Astin Buton Astuti Tuharea Cut Bidara Panita Umar Hikmawati Hikmawati Irma Yanty Larajasi Jayanti Djarami Marasabessy, Nur Baharia Maryam Lihi Moh. Nurul Iman Wokas Muhammad Azril Hardiman Mahulauw Nadhira Fahreza Patimahu Nur Hardianti.Walalayo Nur’in Aihena Pia Batmomolin Rokia Latuamury Sahril Sillehu Sultina Syari Tunny, Risman Yuni Widiastuti Hayoto