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All Journal Medical Journal of Indonesia The Indonesian Biomedical Journal Molecular and Cellular Biomedical Sciences (MCBS) Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Amerta Nutrition World Nutrition Journal Narra J eJournal Kedokteran Indonesia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Fiastuti Witjaksono
Department Of Nutrition, Faculty Of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : World Nutrition Journal

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Selenium in Hyperthyroidism Shiela Stefani; Lukman Halim; Diyah Eka Andayani; Fiastuti Witjaksono
World Nutrition Journal Vol. 3 No. 2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i2.0004

Abstract

Introduction: Thyroid gland has the highest selenium content compare with other endocrine organs. Enzyme that catalyzing thyroid hormone activation, iodothyronine deiodinases, were identified as selenocysteine-containing proteins. Selenium levels in soil and rice consumed in Indonesia were lower than in several other countries, which can increase the risk of selenium deficiency.Methods: This is an article review of the current literatures published up to November 2018 about the role of selenium in hyperthyroid.Result: Several studies have shown that selenium supplementation can be beneficial in patients with Graves disease and autoimmune thyroiditis. Selenium has an important immunomodulatory effect, but the effects of selenium supplementation in hyperthyroid has not been conclude. Data regarding selenium intake, prevalence of deficiency, and the relationship between selenium and thyroid disease in Indonesia are limited. Various studies of selenium supplementation in thyroid disease provide controversial results, so there are no guidelines that include selenium as standard therapy hyperthyroid. Selenium supplementation can enhance the restoration of biochemical euthyroidism in Graves disease and was associated with a significant decrease in the levels of thyroid peroxidase antibodies in autoimmune thyroiditis.Conclusions: Micronutrients that play a role in thyroid hormone synthesis and maintain thyroid function in addition to selenium are iodine, iron, zinc, and vitamin A. By correcting the deficit of selenium, and meeting other micronutrient requirements may provide health benefits in patient with hyperthyroid.
A diagnostic test for malnutrition in adults: mid-upper arm circumference towards body mass index: A literature review Fathiyyatul Khaira; Fiastuti Witjaksono; Diyah Eka Andayani
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0012

Abstract

Body mass index is commonly used for detecting malnutrition. At certain conditions, body mass index cannot be measured, so mid-upper arm circumference can be an alternative measurement for detecting malnutrition. Several studies have proposed the cut-off point of mid-upper arm circumference in adults along with its sensitivity, specificity, and area under the ROC curve (AUC). This article aims to describe the diagnostic test for malnutrition using the upper arm circumference in adults and summarize the results of the related studies.
Protein and iron intake adequacy among high school girls in Depok, Indonesia Meirina Khoirunnisa; Yoga Devaera; Umi Fahmida; Fiastuti Witjaksono; Erfi Prafiantini
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0004

Abstract

Introduction: Iron deficiency anemia is the most common type of anemia among adolescent girls. The prevalence of anemia among pregnant women increased from 2013 to 2018, and females age 15-24 years had the highest prevalence of anemia. Therefore, knowing the baseline status of protein and iron intake —particularly animal-sourced protein as the main source of heme iron—is important to design future intervention program. Thus, this study was aimed to assess the protein and iron intake adequacy of High School girls in Depok, Indonesia. Methods: 211 girls from Senior High School in Depok, Indonesia participated in this study. Subjects were selected using a multi-stage random sampling method. A questionnaire was administered to obtain general characteristics. Dietary intake data were obtained using a 3-day non-consecutive 24hr recall 1 weekend 2 weekdays interview. Anthropometric status was measured and calculated. Data were analyzed using IBM SPSS Statistics 20. Spearman’s correlation (significance p<0.05) was used to determine the factors related to protein and iron intake. Results: This population had inadequate intake of energy (97.2%), protein (59.7%), and iron (98.6%). However, intake of fat was higher than recommended in 59.2% of participants. Protein and iron intake were not correlated with age, father’s education, mother’s education, and the number of household member.
Correlation of calorie intake with 24-hour urinary urea nitrogen level changes in critically ill patients at RSUI Depok, Indonesia Githa Putri Puspita Sari; Witjaksono, Fiastuti; Sutanto, Krisadelfa; Singal, Anna Maurina
World Nutrition Journal Vol. 8 No. S1 (2024): Selected conference proceedings of the Nutri Symposium 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.S1.0041

Abstract

Calorie together with protein intake has been proven to be important factors that play a role in critically ill patients. Hypermetabolism in the early acute phase increases energy expenditure and calorie requirement. Insufficient calorie intake will increase protein degradation for gluconeogenesis, which can be assessed by the level of 24-hour urinary urea nitrogen (UUN). Adequate daily calorie intake is expected to improve the UUN level in patients. This study aims to investigates the correlation of calorie intake with UUN level changes in critically ill patients.
Correlation of energy and protein intake with nitrogen balance changes in late acute phase critically ill patients Githa Putri Puspita Sari; Witjaksono, Fiastuti; Sutanto, Krisadelfa; Singal, Anna Maurina
World Nutrition Journal Vol. 8 No. i2 (2025): Volume 08 Issue 2, February 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i2.0007

Abstract

Background: The hypercatabolic process due to metabolic stress in critically ill patients, especially in the acute phase, is very high, causing protein degradation. Inadequate intake and high protein losses will result in a negative nitrogen balance. Objective: To analyze the correlation of energy and protein intake in the late acute phase with nitrogen balance changes. Methods: This study’s method was cross−sectional with consecutive sampling, conducted in the ICU of the university of Indonesia hospital. Energy and protein intake were assessed for 7 days. On days 3 and 7 of treatment, 24−hour urine urea nitrogen levels and nitrogen balance (NB) were assessed. Twenty three subjects participants in this study. Results: There was a positive correlation between energy and protein intake with NB on day 3 (r=0.5, p=0.01 ;r=0.6, p=0.003). The mean nitrogen balance changes was positive, namely 3.8 g. There was a significant correlation between energy and protein intake with NB changes (p>0.01) Conclusion: Energy and protein intake were positively correlated with nitrogen balance in the early acute phase. The results show that the administration of energy and protein starting at low intake in the early acute phase and gradually reaching the target intake during the late acute phase leads to an improvement in nitrogen balance.
Co-Authors Aditya Rachman Aditya Rachman, Aditya Agus Rizal Ardy Hariandy Hamid, Agus Rizal Ardy Hariandy Agus Siswanto Akmal Taher Amanda Pitarini Utari Andhika A. Perdana Andrijono Andrijono Andry Kelvianto Anni Rahmawati Anthony Eka Wijaya Ari Wijayanti Asmarinah Batara Bisuk Daniel Martin Simadibrata Dewi Krisna Yunda Diyah Eka Andayani Diyah Eka Andayani E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Fajriani, Rosalina Fariz, Nurwidya Fathiyyatul Khaira Ferry Safriadi Fitriyadi Kusuma Githa Putri Puspita Sari Haloho, Raja Mangatur Harahap, Alida Roswita Imam Subekti Julianto Witjaksono Kaka Renaldi Kuntjoro Harimurti Lukman Halim Marcellus Simadibrata Marcellus Simadibrata Megantara, Marcelino A. Meirina Khoirunnisa Murdani Abdullah Murdani Abdullah Mustikarani, Dewi Mutiara Riani Mutiara, Rizka Muzellina, Virly Nanda Nasrun, Martina W. Nur Rasyid Ponco Birowo Rabbinu Rangga Pribadi Raja Mangatur Haloho Retno Asti Werdhani Rizka Mutiara Rudi Putranto Savira, Missy Shiela Stefani Simadibrata, Daniel Martin Singal, Anna Maurina Siti Setiati Sri Mutya Sekarutami Sri Wuryanti Suhendro Suwarto, Suhendro Susworo Susworo Sutanto, Krisadelfa Suzanna Immanuel Umi Fahmida Widi Atmoko Wistara, Sevita Sathya Wulandari, Yohannessa Yoga Devaera Yohannessa Wulandari