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All Journal Media Teknik Sipil Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Jurnal Kesehatan Andalas Math Didactic: Jurnal Pendidikan Matematika JURNAL BAHASA, SASTRA DAN PEMBELAJARANNYA Scientific Journal of Reflection : Economic, Accounting, Management and Business Buletin Ilmiah Nagari Membangun SIGMA Majalah Kedokteran Andalas Jurnal Pengabdian Masyarakat Multidisiplin DEDIKASI PKM Jurnal Ekonomi Efektif The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Detector: Jurnal Inovasi Riset Ilmu Kesehatan JURNAL RUMPUN MANAJEMEN DAN EKONOMI Jurnal Intelek Dan Cendikiawan Nusantara Jurnal Intelek Insan Cendikia Jurnal Ilmiah Manajemen dan Akuntansi
Darmadi Darmadi
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Pendekatan Klinis pada Hepatitis C Kronik Sherina Aditya; Darmadi Darmadi
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 4 No. 1 (2026): Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v4i1.5855

Abstract

Viral hepatitis is a systemic disease that primarily affects the liver and is characterized by a necroinflammatory process that plays a significant role in clinical and laboratory manifestations. Chronic hepatitis is defined as liver inflammation lasting more than six months, with persistent elevations in aminotransferases and characteristic histological features, and carries a risk of progression to cirrhosis and hepatocellular carcinoma. Chronic hepatitis C virus infection occurs due to an ineffective host immune response to the virus, allowing the infection to persist. The innate immune system, particularly type I interferon, plays a key role in the initial defense mechanisms against viral replication. Various antiviral therapies, such as interferon, nucleoside analogs, and nucleotide analogs, are currently available, which have been shown to reduce viral load and inhibit disease progression. Appropriate therapy is expected to prevent long-term complications in patients with chronic hepatitis.
Co-Authors Adhe Winda Septiana Adnan Adnan Amira Hafsari Annisa Pusvita Sari Arnentis Arnentis Athaya Hasna Abiyya Bella Dianda Utami Benny Handoyo Brilian Dini MA Iballa Desy Pitriyani Dwi Mayasari Eli Yusrita Ellyza Nasrul Evi Suryawati Faisal Faisal Fitra Suzanti Floryani Natalin Yuantri Galuh Adjie Saputra Gebi Yantri Matondang Gontar Alamsyah Siregar Hasanati Hasanati Ika Krisdiana Ilham Kurniati Imam Mahadi Iman Syatoto Imma Widyawati Agustin ismaningsih, ismaningsih Leonardo Basa Dairi Mariani Natalina Mariani Natalina L Mega Pratiwi Irawan, Mega Pratiwi Mohammad Andri Mughni Hardiyani Muhamad Guruh Muhammad Amin Muhammad Saleh Muhammad Zainul Arifin N Lilis Suryani Noto Susanto Nuzulia Irawati Oktavia Safitri Putri Novi Ani Sinaga Rahmad Setiawan Rahmi, Fitri Olvia RATNA SARI Riska Habriel Ruslie Riski Karmila Risma Widia Salza Haditsah, Mitha Sania Audry Nasution Sherina Aditya Siti Juariah Siti Juariah Siti Namiroh suwondo suwondo Syahmila Nanda Fani Tini Anggraini Simamora Titin Masfingatin Wan Syafi’i Wasilatul Murtafiah Woro Dyah Ayu Pratiwi