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All Journal bionature Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Proceeding Buffalo International Conference Biogenesis: Jurnal Ilmiah Biologi Teknosains: Media Informasi Sains dan Teknologi Prosiding Seminar Biologi Jurnal Biodjati Celebes Biodiversitas : Jurnal Sains dan Pendidikan Biologi BIOTROPIC The Journal of Tropical Biology AL-HAYAT: Journal of Biology and Applied Biology Al Jahiz: Journal of Biology Education Research Filogeni: Jurnal Mahasiswa Biologi Berita Biologi
Fatmawati Nur
Universitas Islam Negeri Alauddin Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Veterinary Other

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Immunomodulatory Effects of Synbiotic Lactic Acid Bacteria from Dangke and Inulin from Dahlia Tubers Febriani, Ayu; Hafsan, Hafsan; Sijid, St Aisyah; Nur, Fatmawati; Muthiadin, Cut; Khudaer, Faten
Al Jahiz Vol 6 No 2 (2025): Al-Jahiz: Journal of Biology Education Research, July-December 2025 (In Progress)
Publisher : Fakultas Tarbiyah dan Ilmu Keguruan UIN Jurai Siwo, Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32332/al-jahiz.v6i2.10393

Abstract

Synbiotics, the synergistic combination of probiotics and prebiotics, have attracted growing scientific interest due to their potential to modulate immune responses. However, the immunomodulatory effects of synbiotics derived from traditional foods remain underexplored. This study aimed to evaluate the immune-enhancing potential of synbiotics formulated from Lactobacillus fermentum isolated from Dangke (a traditional South Sulawesi cheese) and inulin extracted from Dahlia tubers. The novelty of this work lies in the utilization of culturally unique, locally sourced microbial and prebiotic components that have not previously been tested for immunological impact. A total of 28 mice were randomly divided into four groups: one negative control group (P0) and three treatment groups (P1, P2, P3) receiving different doses of synbiotics over a 20-day treatment period. Parameters observed included changes in body weight, macrophage phagocytosis activity, and organ indices (liver and spleen). Results showed that mice in P1 and P2 groups exhibited significant increases in body weight (P1: +12.5%, P2: +15.3%, p < 0.05) compared to the control. Moreover, macrophage phagocytic activity was markedly improved in the treatment groups (p < 0.01). Liver and spleen indices were also significantly elevated (p < 0.05), indicating enhanced organ function. These findings suggest that synbiotics containing L. fermentum and Dahlia inulin have promising immunomodulatory effects, highlighting their potential for development as novel functional food ingredients with health-promoting benefits.
Identifikasi tanaman mangrove di Sungai Tallo, Makassar, Sulawesi Selatan Fahmi, Muhammad Aldy Fachrial; Nur, Fatmawati; Saenab, Siti
Filogeni: Jurnal Mahasiswa Biologi Vol 1 No 1 (2021): Januari-April
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (742.686 KB) | DOI: 10.24252/filogeni.v1i1.20551

Abstract

Pelestarian hutan mangrove sangat penting dilakukan mengingat banyaknya manfaat dan kegunaan hutan mangrove dalam berbagai aspek kehidupan. Penelitian ini merupakan penelitian deskriptif secara visual yang dilakukan untuk mengetahui jenis-jenis mangrove yang ada di sungai Tallo kota Makassar Sulawesi Selatan. Metode yang digunakan adalah Line Transect dimana metode ini menggunakan plot yang disejajarkan pada garis yang telah ditentukan, terdapat 4 stasiun utama di sepanjang area penelitian, setiap stasiun terdapat 4 plot, dengan jumlah total plot sebanyak 16 plot, selanjutnya tumbuhan mangrove yang dijumpai diidentifikasi berdasarkan ciri morfologinya dengan melihat akar, batang, daun, bunga, buah dan biji. Hasil identifikasi menunjukkan bahwa di area sungai Tallo terdapat 5 jenis mangrove sejati yaitu Avicennia marina, Nypa Frutican, Rhizopora apiculata, Rhizopora mucronata, dan Sonneratia caseolaris.
Keanekaragaman jenis fitoplankton di perairan tambak udang putih di Kelurahan Bonto Kamase, Kecamatan Herlang, Kabupaten Bulukumba Mildasari, Mildasari; Nur, Fatmawati; Hasyimuddin, Hasyimuddin; Dirhamzah, Dirhamzah
Filogeni: Jurnal Mahasiswa Biologi Vol 1 No 3 (2021): September-Desember
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (649.179 KB) | DOI: 10.24252/filogeni.v1i3.25606

Abstract

Fitoplankton merupakan mikroorganisme perairan yang memiliki peran sebagai bioindikator tercemarnya air dan organisme pengahasil makanan pertaman dalam rantai makanan di perairan. Penelitian ini dilakukan di tambak udang putih di Kelurahan Bonto Kamase, Kecamatan Herlang, Kabupaten Bulukumba. Analisis data yang digunakan adalah indeks keanekaragaman jenis dengan tujuan mengetahui kualitas air berdasarkan indeks keanekaragaman fitoplankton pada pertambakan udang putih. Pengambilan sampel air dilakukan di tiga stasiun pada waktu siang dan malam hari dan mengukur parameter fisika kimia perairan. Hasil identifikasi didapatkan berjumlah 21 spesies terdiri lima kelas yaitu kelas Bacillariophyceae, Chlorophycea, Cyanophyceae, Euglenaphyceae, Dinophyceae. Kelimpahan fitoplankton pada stasiun 1 siang hari yaitu 222 ind/l sedangkan pada malam hari 139.3 ind/l yang didominasi oleh Euglena dan Oscilatoria sp. Stasiun 2 siang hari yaitu 196.3 ind/l dan malam hari yaitu 184.6 ind/l yang didominasi oleh Mikrocystis aeruginosa. Sedangkan stasiun 3 siang hari yaitu 151 ind/l dan malam hari yaitu 136 ind/l yang didominasi oleh Euglena sp. Indeks keanekaragaman jenis di seluruh stasiun tergolong tinggi (H’>3,0) dan tergolong sedang (H’<3,0-1,0) serta kualitas air di perairan tambak termasuk perairan yang sangat cocok untuk kegiatan budidaya.
Uji histopatologi sebagai metode baru dalam diagnostik penyakit rabies pada anjing liar Nurlia, Nurlia; Nur, Fatmawati; Wirawan, Hadi Purnama
Filogeni: Jurnal Mahasiswa Biologi Vol 3 No 2 (2023): Mei-Agustus
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/filogeni.v3i2.29550

Abstract

Peningkatan kasus gigitan anjing memicu kekhawatiran masyarakat akan penularan penyakit rabies, padahal tidak semua gigitan anjing akan menyebabkan infeksi penyakit rabies. Rendahnya sensitivitas diagnosis secara klinis sehingga dibutuhkan metode diagnostik dengan hasil yang lebih akurat, salah satunya melalui pemeriksaan laboratorium dengan uji histopatologi. Tujuan penelitian yaitu untuk diagnosis penyakit rabies pada anjing liar dengan uji histopatologi untuk mengetahui terinfeksi atau tidaknya anjing yang diuji. Penelitian ini menggunakan uji histopatologi dengan sampel jaringan hippocampus. Hasil penelitian menunjukkan bahwa pada sampel uji, tidak ditemukan adanya negri bodies yang menandakan bahwa sampel anjing yang dijadikan hewan uji tidak mengidap penyakit rabies (tidak terinfeksi virus rabies).
Analisis kadar nitrit pada air sumur menggunakan spektrofotometer UV-Vis di Laboratorium Lingkungan Hidup Makassar Aguslianti, Yunita; Nur, Fatmawati; Rosmah, Rosmah
Filogeni: Jurnal Mahasiswa Biologi Vol 3 No 3 (2023): September-Desember
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/filogeni.v3i3.34749

Abstract

Air merupakan salah satu senyawa yang memiliki peranan penting bagi kehidupan. Manusia banyak memanfaatkan air untuk kehidupan sehari-hari. Salah satu sumber air yang banyak dikonsumsi oleh manusia adalah air yang berasal dari sumur gali. Air sumur memiliki banyak kelemahan karena dapat terkontaminasi oleh zat-zat mineral berbahaya salah satunya ialah air memiliki banyak kandungan nitrit. Nitrit dapat menyebabkan methemoglobinemia yang berbahaya bagi kesehatan. Tujuan dari penelitian ini adalah untuk mengetahui kadar nitrit pada air sumur menggunakan spektrofotometer dan mengetahui batas deteksi berdasarkan SNI. Metode penelitian ini berupa penelitian deskriptif berbasis laboratorium dan berdasarkan pengujian SNI. Hasil yang didapatkan pada penelitian ini yaitu kadar nitrit yang diperoleh dari sampel air sumur berkisar antara -0,015 - 0,016 mg/L, dan dapat dikatakan masih memenuhi standar mutu Permenkes Nomor 32 Tahun 2017 yaitu kurang dari 1 mg/L sehinga air sumur tersebut dapat digunakan dalam kehidupan sehari-hari.
Volatile Profiling of Root-Shoot and Fruits of Capsicum frutescens var. Salo Dua from Enrekang, Indonesia Nur, Fatmawati; Meriem, Selis
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.10003

Abstract

Capsicum frutescens var. Salo Dua is a local variety cultivated in Enrekang Regency, South Sulawesi. It has unique traits of color transition during fruit ripening and extended post-harvest shelf life. However, the metabolite profiling in this potential variety has not been explored. This was an initial study that aimed to profile the volatile compounds in the root-shoot parts (as vegetative) and in the ripe fruits of Salo Dua variety. The instrument of Gas Chromatography coupled with Mass Spectrometry (GC-MS) was used to separate and characterize the volatile compounds. Our study revealed a higher number of forty-two volatiles in the ripe fruits compared to the twenty-eight volatiles in the shoot-root parts. The five major compositions of the chemical class in ripe fruits were characterized by the formation of alcohols (26%) followed by esters (19%), alkaloids (10%), fatty acids (10%), and ketones (7%). While the abundant volatiles in the root-shoot parts were shown by the presence of esters (29%), alcohols (21%), fatty acids (18%), alkaloids (11%), and heterocyclic (7%). There were nineteen volatiles that only emitted in the ripe fruits. Of which, capsaicin and dihydrocapsaicin were detected in the ripe fruits with an average relative area of 1% and 0.51%, subsequently.
INTRODUCTION OF THE SYNBIOTIC OF LACTIC ACID BACTERIA FROM DANGKE AND INULIN DAHLIA IN MICE INFECTED WITH Enteropathogenic Escherichia coli Nur, Fatmawati; Hadidarma, Nasyrah; Hafsan, Hafsan; Muthiadin, Cut; Khudaer , Faten
Berita Biologi Vol 23 No 2 (2024): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/beritabiologi.2024.3733

Abstract

This study investigates the influence of synbiotics, a combination of probiotics (lactic acid bacteria) and prebiotics (inulin from Dahlia tubers), on mice infected with Enteropathogenic Escherichia coli (EPEC) bacteria. The performance of mice, including weight gain, feed consumption, and feed conversion ratio, was used as parameters to understand the effect of synbiotics on EPEC-infected mice. Four groups of mice were observed in this study: the control group (P1), EPEC infection group (P2), synbiotics introduction group (P3), and synbiotics introduction + EPEC infection group (P4). The research findings demonstrate that synbiotics from Dangke lactic acid bacteria and inulin from Dahlia tubers have a positive impact on mice performance and help them in countering EPEC infection. Group P3, which received synbiotics without EPEC infection, showed significantly higher weight gain and feed conversion efficiency compared to groups P1 and P2. The synbiotics contributed to the enhancement of mice growth and feed efficiency. On the other hand, group P4, which received synbiotics and was infected with EPEC, exhibited a lower survival rate compared to the control group (P1) and group P3, despite having a shorter duration of diarrhea. EPEC caused diarrhea in mice, but synbiotics helped reduce the duration of diarrhea by inhibiting the growth and attachment of EPEC in the mice's intestines. These findings indicate that synbiotics of Lactic Acid Bacteria and inulin Dahlia have the potential as an alternative strategy to improve mice growth and intestinal health. However, the positive effect of synbiotics may be diminished when mice are infected with EPEC.
Co-Authors Ade Muspa Aguslianti, Yunita Andi Nur Fadhilah Andi Nur Fadhilah, Andi Andi Wahdiniar Andi Wahdiniar, Andi Baiq Farhatul Wahidah Cut Muthiadin Darmilan Darmilan Dirhamzah, Dirhamzah Erna Afdal Ernitasari, Ernitasari Fahmi, Muhammad Aldy Fachrial Faten Khudair Febriani, Ayu Hadidarma, Nasyrah Hafsan, Hafsan Hasyimuddin Hasyimuddin Hasyimuddin Hasyimuddin Hasyimuddin, Hasyimuddin Indriani Indriani Karneli K, Karneli Karneli Karneli Khudaer , Faten Khudaer, Faten Kurnia Kadir Kusnadi Alimuddin Marliana Marliana Mashuri Masri - Masriany, Masriany Meriem, Selis Mildasari, Mildasari Muhammad Halifah Mustami, Muhammad Muhammad Khalifah Mustami Ninin Andrini Nurlailah Mappanganro Nurlia Nurlia Rosmah, Rosmah Rukmana, Rusmadi Rusmadi Rukmana Saenab, Siti Sijid, St Aisyah Siti Rabiatul Adawiyah Siti Rabiatul Adawiyah, Siti St. Aisyah Sijid St. Aisyah Sijid Sukmawaty, Eka Suriani Suriani Ulfa Triyani A Latif Ulfa Triyani A Latif Ummi Aminah Wirawan, Hadi Purnama Yul Fitriani Zulijjah Amin Zulkarnain Zulkarnain Zulkarnain Zulkarnain Zulkarnain Zulkarnain