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UJI DIFUSI MIKROEMULSI NITROGLISERIN MENGGUNAKAN TWEEN 80 SEBAGAI SURFAKTAN Yati, Kori; Situmorang, Almawati; Umoro, Ani
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 9, No 1 (2017): Punica Granatum
Publisher : Indonesian Research Gateway

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Abstract

ABSTRACT: Nitroglycerine is a drug of choice in the treatment of angina pectoris. Nitroglycerine has low dose, short time of plasma half life and liver metabolizing. This study used the formulation of microemulsion. The advantages of microemulsion transparent form, stable and has better skin penetration due to the smaller size of its droplet. This study aims at determining concentration of Tween 80 as surfactant as penetration in the nitroglycerine microemulsion. Tween 80 concentrations used were 40% (F1), 42,5% (F2) and 45% (F3). Penetration ability was tested by invitro using Franz diffusion cells. The results showed that 42,5% of the concentration of Tween 80 produces good penetration. F2 shows the measurement result of droplet size is 69,0 nm and diffusion test on the minutes of 180 for 86,00% ± 3,65. It can be concluded that the concentration of Tween 80 as surfactant of 42,5% gives microemulsion nitroglycerine with good penetration.
UJI DIFUSI MIKROEMULSI NITROGLISERIN MENGGUNAKAN TWEEN 80 SEBAGAI SURFAKTAN Yati, Kori; Situmorang, Almawati; Umoro, Ani
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (9030.693 KB) | DOI: 10.35617/jfi.v9i1.557

Abstract

ABSTRACT: Nitroglycerine is a drug of choice in the treatment of angina pectoris. Nitroglycerine has low dose, short time of plasma half life and liver metabolizing. This study used the formulation of microemulsion. The advantages of microemulsion transparent form, stable and has better skin penetration due to the smaller size of its droplet. This study aims at determining concentration of Tween 80 as surfactant as penetration in the nitroglycerine microemulsion. Tween 80 concentrations used were 40% (F1), 42,5% (F2) and 45% (F3). Penetration ability was tested by invitro using Franz diffusion cells. The results showed that 42,5% of the concentration of Tween 80 produces good penetration. F2 shows the measurement result of droplet size is 69,0 nm and diffusion test on the minutes of 180 for 86,00% ± 3,65. It can be concluded that the concentration of Tween 80 as surfactant of 42,5% gives microemulsion nitroglycerine with good penetration.
PERBANDINGAN VCO, MINYAK ZAITUN DAN MINYAK JAGUNG TERHADAP SIFAT FISIK BALSEM STIK DENGAN PENGIKAT VASELIN ALBA ATAU ADEPS LANAE Lestari, Pramulani Mulya; Yati, Kori; Rosanti, Mimil
Jurnal Farmasi Indonesia Vol 11, No 2 (2019)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v11i2.671

Abstract

The use of balm by applying it to the affected part of the body can cause heat and stickiness in the fingers. Making balm sticks is one solution to overcome this problem. Balm sticks are influenced by the components used are oils, waxs and fats. Oils and fats have different fat acid and molecul weight will affect the physical properties of balm stick. Selection of the proper components are excepted to good melting point and hardness and in accordance with requirments. This study aimed at compare of VCO, olive oil and corn oil with variation between Adeps lanae and Vaselin albaon the physical properties of stick balm. All balm sticks prepared by the same method and evaluated included organoleptic test, homogenity, hardness and melting point. The result showed that difference in melting point and hardness, but all formula meet the requirment of physical preparation balm stick. Formula with VCO and Adeps lanae shows higest melting point and hardness. Statistical result of Kruskal Wallis shows sig <0,05 which means that there were difference of each formula. It could be concluded that VCO with Adeps lanae in combination Carnauba wax and Cera alba g a ve a high melting poin , hardenss and yield value.
Edukasi Pengenalan Dan Pengendalian Bahaya Potensial Pekerjaan Pada Guru SD Muhammadiyah 16 Dan 15 Bukit Duri Mawanti, Wening Tri; Harahap, Roito Elmina Gogo; Yati, Kori; Setiawan, Abdul Aziz; Khoirunisa, Irbah; Intan, Annisa; Abdulloh, Abdulloh
Jurnal SOLMA Vol. 14 No. 2 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i2.15248

Abstract

Background: Upaya penerapan Keselamatan dan Kesehatan Kerja di sekolah melalui edukasi pengenalan dan pengendalian bahaya potensial terutama bagi para guru penting dilakukan agar proses belajar-mengajar tidak terhambat yang diakibatkan oleh guru yang cidera atau sakit. Meningkatkan pengetahuan setiap guru tentang berbagai bahaya potensial pekerjaannya dan mampu melakukan langkah pengendalian terhadap bahaya potensial yang ditemukan. Metode: Metode yang digunakan adalah penyuluhan atau edukasi ceramah dengan penyajian materi selama 30 menit, diikuti diskusi tanya jawab. Peserta yang terlibat adalah guru SD Muhammadiyah 16 dan 52 Bukit Duri. Peningkatan pengetahuan diukur dengan melakukan pre-tes sebelum ceramah dan dilakukan post-test setelah ceramah. Hasil pre-test dan post-test dilakukan analisis menggunakan program IBM SPSS Statistic 24 metode uji paired T-test. Hasil: Nilai Korelasi antara 2 variabel pretest dan posttest responden penyuluhan “Edukasi Potensi Bahaya Keselamatan dan Kesehatan Kerja Guru di SDN Muhammadiyah 16 dan 52 Bukit Duri” sebesar 0,632, artinya terdapat hubungan yang hubungan kuat dan positif. Nilai probabilitas/p value uji T Paired sebesar 0,027, artinya terdapat perbedaan antara sebelum dan sesudah perlakuan, sebab nilai p value < 0,05 (95 % kepercayaan). Kesimpulan: Edukasi pengenalan dan pengendalian bahaya potensial pekerjaan efektif dalam meningkatkan pengetahuan Guru SD Muhammadiyah 16 dan 52 Bukit Duri.
Inovasi pengharum ruangan sustainable: pelatihan lilin aromaterapi dan soy wax sachet di Rusunawa Rorotan Siska, Siska; Bariroh, Tahyatul; Fatmawati, Sofia; Rindita, Rindita; Riyanti, Hurip Budi; Yati, Kori
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 5 (2025): September (In Progress)
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i5.30886

Abstract

Abstrak Aromaterapi merupakan terapi pelengkap yang memanfaatkan minyak atsiri dari tanaman beraroma yang mudah menguap dan memberikan efek relaksasi serta manfaat kesehatan. Rusunawa Rorotan memiliki unit hunian terbatas sekitar 30 m², sehingga warga memerlukan kegiatan yang dapat menghilangkan kejenuhan sekaligus meningkatkan keterampilan. Tujuan utama kegiatan ini meliputi peningkatan pemahaman, penerapan gaya hiudp berkelanjutan, pengembangan keterampilan kreatif, penciptaan peluang ekonomi mikro, serta peningkatan kesejahteraan psikologis melalui stimulus olfaktori dan visual. Kegiatan meliputi registrasi, penyampaian materi, praktik pembuatan produk, serta evaluasi melalui pre dan post test. Hasil evaluasi menunjukkan peningkatan signifikan dalam pengetahuan peserta, terlihat dari nilai rata-rata pre-test dan post-test yang berturut-turut mencapai 65,8 dan 82,57, serta respons positif peserta terhadap produk yang mudah dibuat (100%), bentuk produk menarik (74%), dan  memiliki aroma wangi (67%) yang berdampak pada peningkatan mood.  Kesimpulan dari kegiatan ini, secara keseluruhan pelatihan aromaterapi tidak hanya mengurangi kejenuhan di lingkungan padat, tetapi juga mendorong transformasi kearifan lokal menjadi solusi kreatif dna berkelanjutan secara ekonomi bagi warga Rusunawa Rorotan.    Kata kunci: aromaterapi; dekoratif; essential oil; sustainable. Abstract Aromatherapy is a complementary therapy that utilizes essential oils from aromatic plants, which are volatile and provide relaxation and helath benefits. Rusunawa Rorotan has limited living units of approximately and health benefits. Rusunawa Rorotan has limited living units of approximately 30 m², residents face challenges related to psychological well-being and limited opportunities for skill development. This community-based training program aimed to enhance participants’ understanding of sustainable lifestyles, promote the practical application of aromatherapy, foster creative skills, generate microeconomic opportunities, and improve psychological well-being through olfactory and visual stimuli. The program consisted of registration, theoretical sessions, hands-on product-making workshops, and evaluation via pre- and post-tests. Results indicated a significant improvement in participants’ knowledge, with average pre-test and post-test scores rising from 65.8 to 82.57, respectively. Furthermore, participant feedback revealed that 100% found the products easy to make, 74% appreciated the attractive design, and 67% noted pleasant aromas that positively influenced mood. In conclusion, the aromatherapy training effectively alleviated mental fatigue in a densely populated environment and successfully transformed local traditional knowledge into innovative, sustainable, and economically viable solutions for the community of Rusunawa Rorotan. Keywords: aromatherahy; decorative; essential oil; sustainable.
ISOLASI PEKTIN DARI KULIT BUAH NAGA (Hylocereus polyrhizus) DAN PEMANFAATANNYA SEBAGAI PENGIKAT PADA SEDIAAN PASTA GIGI Yati, Kori; Ladeska, Vera; Wirawan, Adi Putra
Media Farmasi: Jurnal Ilmu Farmasi Vol. 14 No. 1: Maret 2017
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v14i1.9824

Abstract

Buah naga selain dikonsumsi dalam bentuk segar juga diolah menjadi beberapa produk olahan. Kulit buah naga mengandung pektin ±10,8%. Pada industri farmasi dan makanan, pektin digunakan sebagai pengikat, pembentuk gel, penstabil, dan pengental. Penelitian ini bertujuan untuk mengisolasi pektin, mengkarakterisasi pektin dan mengetahui pengaruh perbedaan konsentrasi pektin sebagai bahan pengikat terhadap viskositas yang dihasilkan pada sediaan pasta gigi. Pektin yang dihasilkan dianalisa secara kualitatif menggunakan FTIR dan memenuhi persyaratan JEFCA ( Joint Expert Committee for Food Additives (FAO/WHO)) dengan nilai susut pengeringan 11,03%, kadar abu 0,41 %, berat ekivalen 617,29 mg dan kadar metoksi 6,50% . Pektin yang sudah dikarakterisasi dibuat pasta gigi dalam 4 formula dengan konsentrasi pektin  sebesar 3%, 3,5%, 4% dan 4,5%, kemudian dievaluasi sifat fisiknya meliputi organoleptis, homogenitas, pH, viskositas dan sifat alir. Dari hasil penelitian menunjukkan bahwa semakin meningkat konsentrasi penggunaan pektin kulit buah naga maka semakin besar pula viskositas yang dihasilkan.