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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Dasar AL KAUNIYAH BERKALA SAINSTEK REKAYASA UNEJ e-Proceeding REINWARDTIA Jurnal Biodjati Caraka Tani: Journal of Sustainable Agriculture BIOEDUKASI JPSCR : Journal of Pharmaceutical Science and Clinical Research Journal of Natural Sciences Makara Journal of Science Jurnal Malikussaleh Mengabdi Life Science and Biotechnology Biosaintifika: Journal of Biology & Biology Education Reinwardtia Jurnal Penelitian Sains dan Teknologi Indonesia Jurnal Hasil Pengabdian Kepada Masyarakat Universitas Jember
Fuad Bahrul Ulum
Department Of Biology, Faculty Of Mathematics And Natural Sciences, Universitas Jember
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Mathematics Physics Public Health Social Sciences Other

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Journal : Makara Journal of Science

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Liparis condylobulbon Reichb. f. from Gumitir, Indonesia: Morphology, Molecular, and Phytochemical Profile Ulum, Fuad Bahrul; Arum, Asyifa Yasmin; Sa’adah, Kurnia; Setyati, Dwi; Dwinianti, Edia Fitria; Rajamani, Ranjithkumar; Nugraha, Ari Satia; Su’udi, Mukhamad
Makara Journal of Science Vol. 30, No. 1
Publisher : UI Scholars Hub

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Abstract

Liparis condylobulbon Rchb.f. is an epiphytic orchid across South and Southeast Asia, which holds notable ethnomedicinal and pharmacological significance. This study aims to characterize Indonesian Liparis condylobulbon using integrated morphological, molecular (matK, rbcL, ITS2), and phytochemical (LC-MS, DPPH) analyses of specimens from Mount Gumitir, providing the first comprehensive taxonomic and pharmacological profile to support species authentication and future bioprospecting. The L. condylobulbon specimen displays diagnostic epiphytic morpho-logy, including fusiform pseudobulbs, two elongate leaves, and an erect inflorescence bearing ~123 flowers. Molecular barcoding using matK, rbcL, and ITS2 confirmed its identity, with phylogenetic analyses consistently clustering it with L. condylobulbon, supporting taxonomic placement despite minor ITS2-based variation. Metabolomic analysis revealed 58 distinct secondary metabolites, including 30 flavonoids, 22 terpenoids, and 6 phenolic compounds, with key bioactives such as diosmin, picrasinoside B, and 6-gingerol exhibiting known anti-inflammatory, antioxidant, and anticancer properties. Although the crude extract showed relatively low antioxidant capacity (IC₅₀ = 650 µg/mL), the chemical diversity and presence of pharmacologically active constituents underscore the species' potential for future phytotherapeutic applications.
Co-Authors AFIATRI PUTRIKA Afiatri Putrika AFIATRI PUTRIKA, AFIATRI Afidah, Yusfi Andiana, Jocelin Angraeni, Devi Silvia Ardiyansah, Muhammad Ari Satia Nugraha Arif Mohammad Siddiq Arsetyo Rahardianto Arum, Asyifa Yasmin ‘Ain, Salsabila Qurrotu DIAN APRIANI DIAN APRIANI DWI INDAHNING ROHMAH Dwi Setyati Dwi Setyati Dwi Setyati Dwinianti, Edia Fitri Dwinianti, Edia Fitria Dyah Retno Wulandari Eny Yuniati Fadri, Firda FADZILAH AG FADZILAH AG. KANAK FADZILAH AG. KANAK, FADZILAH AG. Farhan, Abdillah Maulana Firda Fadri Fitri, Edia Fitri, Nurfajri Eka Gilani, Noor Azizah Hayyinah, Asa Hanifatul Hidayat Teguh Wiyono Hidayatullah, Alhabsy INDAH WAHYUNI Indah Wahyuni KANAK KANJANA WONGKUNA KANJANA WONGKUNA KANJANA WONGKUNA, KANJANA Khoirunnisa, Gita Ayu Kurniawan, Ludfi Laili, Alvina Nur LESLEY C. LUBOS LESLEY C. LUBOS LESLEY C. LUBOS, LESLEY C. LUONG THIEN TAM LUONG THIEN TAM LUONG THIEN TAM, LUONG THIEN M. Akbar, Salahuddin Miatin Alvin Septianasari MIKA RIZKI PUSPANINGRUM Mika Rizki Puspaningrum MIKA RIZKI PUSPANINGRUM, MIKA RIZKI Moh. Ikmal Alfi Rizqoni MOHD RAWIYANI PG. HJ. SERUDIN MOHD RAWIYANI PG. HJ. SERUDIN MOHD RAWIYANI PG. HJ. SERUDIN, MOHD RAWIYANI PG. MONICA SULEIMAN MONICA SULEIMAN MONICA SULEIMAN, MONICA Mudinillah, Adam Muhammad Ardiyansah Mukhamad Su'udi Mukhamad Su'udi Mukhamad Su'udi Mukhamad Su’udi Munaa Aqidatul Ulaa MUSYAROFAH ZUHRI Musyarofah Zuhri Musyarofah Zuhri NG AIK MIN NG AIK MIN NG AIK MIN, NG AIK Nurfajri Eka Fitri NURLISMA JUNITA NURLISMA JUNITA NURLISMA JUNITA, NURLISMA Nursahara Pasaribu Nursahara Pasaribu NURSAHARA PASARIBU Rajamani, Ranjithkumar Ratnasari, Tri Rendy Setiawan Rizqoni, Moh Ikmal Alfi ROBBERT GRADSTEIN ROBBERT GRADSTEIN ROBBERT GRADSTEIN, ROBBERT Rosida, Waki'atil Rosida, Wakiatil Rosyadi, Achmad SATRIYAS ILYAS Sattya Arimurti Sa’adah, Kurnia SOONTHREE KORNOCHALERT SOONTHREE KORNOCHALERT SOONTHREE KORNOCHALERT, SOONTHREE Su'udi, M. Su'udi, Mukhamad Sudarmadji, S. Sulistiyowati, Hari Sutoyo Su’udi, Mukhamad Tri Handoyo Ulaa, Munaa Aqidatul Veren Yuliana Saputri Wulandari, Dyah Retno YONG KIEN–THAI, YONG YONG KIEN–THAI YONG KIEN–THAI