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All Journal Jurnal Pengajaran MIPA STRATEGIC Meditory : The Journal of Medical Laboratory Jurnal Analis Kesehatan JPP Jurnal Kesehatan Poltekkes Palembang Journal of Indonesian Medical Laboratory and Science (JoIMedLabS) Mukhtabar: Journal of Medical Laboratory Technology Jurnal Kesehatan Siliwangi Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Nina Marliana, Nina
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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The The Effect of Blood Transfusion Frequency on Secretor Status Titer in Saliva and Urine Specimens of Thalassemia Patients Darmantoputro, Feby Wicaksono; Nurhayati, Betty; Hayati, Eem; Marliana, Nina
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.308

Abstract

Background: Thalassemia is a disease caused by a deficiency or loss of synthesis of one or more normal globin chains. In diseases that require blood transfusions, such as Transfusion Dependent Thalassemia (TDT), it is very important to examine the blood type to determine the blood to be transfused. The ABO blood type system antigen or secretor, is found in body fluids in the form of dissolved antigens, including in saliva and urine. Interference can be caused by the frequency of transfusion, which can change the secretor content in the saliva and urine of thalassemia patients, causing false negatives in the examination of secretor status. Objectives: This study aims to determine the effect of transfusion frequency on the titer of secretor status in saliva and urine specimens of Thalassemia patients. Materials and Methods: The type of study is quasi-experimental, Agglutination-Inhibition method. The research sample was 23 Thalassemia major patients. 15 patients are secretor patients, with a frequency of 1x transfusion a month were 7 people (47%), a frequency of 2x transfusion a month were 5 people (33%), and 4x transfusion a month were 3 people (20%). Results: The results of the study on Thalassemia patients obtained from saliva were titers between 1/8 to 1/256. From urine, the results were non-secretors. In contrast to previous studies, which stated that urinary is still detected but four times weaker than saliva. Based on the ANOVA statistical calculation, sig. 0.909 (p>0.05) was obtained. Conclusions: The conclusion is that there is no effect of transfusion frequency on the titer of secretor status in saliva or urine.
THE EFFECT OF TEMPERATURE AND STORAGE DURATION OF WASHED RED CELLS ON THE NUMBER OF ERYTHOCYTES Andina, Chika Alivia; Noviar, Ganjar; Marliana, Nina; Hayati, Eem
Meditory : The Journal of Medical Laboratory Vol 12, No 2 (2024): Meditory, Volume 12 No. 2 Tahun 2024
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v12i2.3428

Abstract

Background: Blood services in Indonesia, including processing and storing donor blood, aim to ensure blood quality remains optimal. Washed Red Cell blood components are used for patients with severe allergies due to repeated transfusions, have a limited shelf life and are susceptible to secondary infections. Aims: Blood services in Indonesia, including processing and storing donor blood, aim to ensure blood quality remains optimal. Washed Red Cell blood components are used for patients with severe allergies due to repeated transfusions, have a limited shelf life and are susceptible to secondary infections. Methods: This research design uses a quasi-experiment with serial time measurements. Samples were taken from one bag of WRC donor blood from the Bandung City PMI Blood Transfusion Unit. Specimens were stored at room temperature (20-25°C) and refrigerator temperature (4-6°C) for 0, 3, 6, and 9 hours, and the number of erythrocytes was measured using a Haematology Analyzer. The results of the study showed that the average number of erythrocytes stored at room temperature was 7.54×10⁶/µL at the 0 hour examination, 6.37×10⁶/µL at the 3 hour examination, 5.40×10⁶/µL at the 6 hour examination. and at the 9 hour examination 4.56×10⁶/µL. Meanwhile, the average number of erythrocytes stored at refrigerator temperature was at the 0 hour examination 7.65×10⁶/µL, at the 3 hour examination 7.43×10⁶/µL, at the 6 hour examination 7.25×10⁶/µL, and at 9 hour examination 7.02×10⁶/µL. The results of the General Linear Model (GLM) statistical test show a sig value = 0.000 0.05. Conclusions: temperature and storage time have a significant influence on the number of erythrocytes.
PEMBERDAYAAN MASYARAKAT UNTUK PENCEGAHAN PENYEBARAN TUBERKULOSIS DI DESA TANIMULYA KECAMATAN NGAMPRAH KABUPATEN BANDUNG BARAT DENGAN MENERAPKAN TEKNOLOGI PEMBUATAN HANDSANITIZER BERBAHAN DASAR DAUN SELEDRI (Apium graveolens L.) Marliana, Nina; Kurniati, Iis; Abror, Yogi Khoirul; Patria, Cecep
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat Kesehatan Indonesia In Progress
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v4i2.4218

Abstract

TB remains a global problem. In our country, TB prevention, including thorough handwashing, is a fairly effective health protocol for preventing TB transmission. Hand sanitizer is an alcohol-based hand cleaning liquid used to reduce contaminating bacteria by up to 99.9% by using it without rinsing with water. This liquid contains various ingredients that very quickly kill bacteria on the skin of the hands. Hand sanitizer aims to remove dirt and flora that stick to our hands. Celery (A. graveolens L.) is a type of vegetable plant with a menthol and distinctive celery aroma. Usually, celery is only used as a complementary ingredient in food preparations, but it turns out that celery contains several beneficial compounds such as flavonoids, saponins, tannins, essential oils as antibacterials. Therefore, celery can be used as a hand sanitizer. The practical goal of this PPDM is for the community in Tanimulya Village, Ngamprah District, West Bandung Regency to process celery for use as a hand sanitizer. The method offered is technology transfer through counseling, training, and mentoring. The target of the PPDM program was Tani Mulya Village in West Bandung Regency, given the dense population and high pollution in the area, necessitating hand sanitizer to prevent the spread of tuberculosis through the hands. The results of the PPDM program in Tani Mulya Village showed an increase in community knowledge and skills, as evidenced by the pre- and post-test results. The average pre-test score was 66.2, while the post-test score increased to 75.7.
Co-Authors Abror, Yogi Khoirul Ade Siswandi Andina, Chika Alivia Arbie, Arbie Arum, Nafilah Darmantoputro, Feby Wicaksono Deswiani, Puri Diana Rochintaniawati Durachim, Adang Eka Y, Dyah Encang Patran Engka Sukarsih Hari Mulyadi, Hari Hayati, Eem Iis Kurniati Kasmanah, Kasmanah Khoirul Abror, Yogi Leni Trisnayanti Maman Sudiman Mamat Rahmat Mariyam, Iyam Merdekawati, Fusvita Mrs Yanti Hamdiyati Musfirani, Nia Najiyyah, Amalia Nur Novia, Ganjar Noviar, Ganjar Nurhayati, Betty Nurhayati, Nuli Patria, Cecep Rohayati rohayati rohayati Rustin, Intang Salsabella Yan Putri, Hanna Zhafira Sriyani Sriyani, Sriyani Tata Maryana Totoy Dahria Trimulyani, Annisa