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Neurological Deafness Prevalence Based on Diabetes Mellitus and Gender Wirayudha, Yan; Kurniati, Yuni Prastyo; Nugraheni, Fladea Eka
Journal La Medihealtico Vol. 5 No. 2 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i2.1115

Abstract

Neurological deafness or sensorineural hearing loss is a hearing loss caused by damage to the cochlea, vestibulocochlear nerve (N.VIII), or the nerve pathways that connect the ear to the brain. Indonesia is part of 4 countries in Asia that have a high prevalence of sensorineural hearing loss, namely 4.6%. Neurological deafness is caused by several factors, including age, genetic factors, and environmental factors. Some studies also show that hypertension, diabetes, and hypercholesterolemia can predispose to neural deafness. One of the complications caused by diabetes mellitus is hearing loss caused by microangiopathy. Gender has also been linked as a risk factor that causes neural deafness. This study aims to determine the relationship between diabetes mellitus and gender with the incidence of neurological deafness in adult patients in the city of Surakarta. This study used secondary data from adult neurologically deaf patients aged >18 years who had diabetes mellitus. This research design uses cross sectional. The total sample size was 67 respondents. The data obtained were analyzed using the chi-square test and logistic regression test. The results of this study stated that there was a relationship between diabetes mellitus and the incidence of neural deafness (p=0.000), there was a relationship between gender and the incidence of neural deafness, namely male gender (p=0.025). A significant relationship was found between diabetes mellitus and gender and the incidence of neurological deafness in adult patients in the city of Surakarta.
Analyzing the Determinants of the Willingness to Receive and Pay for COVID-19 Vaccines Prior to the Commencement of Vaccination in Indonesia Using a Mixed-method Study Romadhon, Yusuf Alam; Lestari, Nining; Firdausi, Nida Faradisa; Kurniati, Yuni Prastyo
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 2 (2022): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.2.2022.155-174

Abstract

Background: The occurrence of various deceptive news on COVID-19 vaccines adversely impact public mindset. Prior to the mass vaccination of Indonesian government, perception of the willingness to be vaccinated and its determinant were not widely explored.Objectives: This study is aimed at evaluating the determinants of willingness to receive and pay for COVID-19 vaccines, prior to the commencement of widespread vaccination in Indonesia.Method: This study applied a cross-sectional design to assess the inhibiting factors of both the willingness to receive and pay for COVID-19 vaccines. Statistical analysis was conducted using bivariate and multivariate methods. Furthermore, a qualitative approach was also adopted to categorize open-ended themes on the determinant of willingness to pay for COVID-19 vaccines.Results: Based on the determinants of willingness to be vaccinated, the following results were obtained, including the occupation of health workers (OR=3.638; p=0.000), civil servants (OR=1.776; p=0.030), perception on COVID-19 as dangerous (OR=2.161; p=0.010), perception on the vaccines as effective (OR= 13,156; p=0.000), perception on vaccine as safe (OR=15,769; p=0.000). In terms of the determinants of willingness to pay, the following results were recorded, including respondents’ age of 40 years (OR=2.048; p=0.000), income of IDR.2,500,000 (OR=1.631;p=0.002), experience from the interaction with COVID-19 patients (OR=1.422; p=0.013), perception on the virus as dangerous (OR=2.211; p=0.000), perception on health protocol discipline (OR=1.834; p=0.014), and perception on the vaccine as effective (OR=1.760; p=0.011). Furthermore, 6 concerns were raised on the willingness/reluctance to pay for the vaccine, such as the perception of the vaccines’ effectiveness and safety, equity, suspicion surrounding the pandemic and vaccine, optional measures in combating the outbreak, personal circumstances and nationalism. Conclusion: The determinants of willingness to receive the COVID-19 vaccine included the occupation of health workers and civil servants, perception of the disease as dangerous, perception of the vaccine as effective and safe. Meanwhile, the factors of willingness to pay included the age range of 40 years, high income, interaction with COVID-19 patients, perception of health protocol discipline and the vaccines’ effectiveness.
Risk Factor Analysis of Residential Topography and Age on Prostate Cancer Incidence Nabilah, Aisyah; Kurniati, Yuni Prastyo
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.52261

Abstract

Prostate cancer is malignancy that originates from the luminal and basal epithelial acinar of prostate gland. Global Cancer Statistics in 2020 stated that prostate cancer is the third most common type of cancer in the world. The incidence and mortality of prostate cancer in Indonesia ranks 10th out of 32 Asian countries. Prostate cancer is multifactorial disease influenced by genetic mutations and inflammation. Research shows risk factors include increasing age and topographical factors of residence. Literature studies from various sources related to age and topography of residence in prostate cancer are still very limited. This study aims to analyze the effect of topographic profile factors of rice fields around the residence and age on the severity of prostate cancer An Observational analytic study was conducted with a case control design. Total of 177 samples using total sampling method. Age variable parameters are less than or more than 65 years. While the topography of residence uses a cut-off point of 39%. The results of the chi-square test found a significant influence between topographic profile of rice fields around the residence with prostate cancer incidence (p = 0.028, OR = 2.155). The results also found a significant influence between age factor with prostate cancer incidence (p=0.018, OR=2.187). The incidence of prostate cancer caused by the topographic profile of residence and age amounted to 7.2%. In conclusion shows that the topographic profile of the rice field area around the residence and age have a significant influence on prostate cancer severity. Keywords: age, pollutant, prostate cancer, residence, rice field
Analysis of The Incidence of Uterine Leiomyoma Based on Body Mass Index and Neutrophil-Lymphocyte Ratio Farma, Aufa Faza Fauzan; Kurniati, Yuni Prastyo
Journal La Medihealtico Vol. 5 No. 5 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i5.1609

Abstract

Leiomyoma is the most common benign uterine tumor in the female with an incidence rate of 70-80%. The cause of these tumors is still unknown, but one of the known causes is that they grow in response to hormonal stimulation. Lymphocytic infiltration in this disease has been identified as an unusual finding. This suggests a potential role for lymphocytes in the development of such tumors. A bibliometric analysis of various sources found minimal research on the Neutrophil-Lymphocyte Ratio (NLR) in uterine leiomyoma, especially in Indonesia. This study analyzed the incidence of uterine leiomyoma based on Body Mass Index (BMI) and Neutrophil-Lymphocyte Ratio (NLR). This study used an observational analytic method with a case-control design. The sampling technique used was consecutive sampling and 129 samples were obtained in the form of 65 uterine leiomyoma case groups and 64 adenomyosis control groups. BMI variable parameters were obesity (>25kg/m2) and not obese (≤25kg/m2), while NLR was at risk (>3.53) and not at risk (≤3.53). Data analysis consisted of univariate, bivariate with a Chi-Square test, and continued with multivariate using logistic regression analysis. There was a significant relationship between BMI and uterine leiomyoma incidence (p = 0.028). There was also a significant relationship between NLR and uterine leiomyoma (p = 0.017). NLR had a 3,688-fold more association with the incidence of uterine leiomyoma than BMI. In conclusion, a relationship exists between BMI and NLR in the incidence of uterine leiomyoma. NLR can be a predictor of uterine leiomyoma, especially in women of reproductive age.
The Influence of Age Factor and Industrial Area on The Malignancy Rate of Bone Tumours Devi, Namira Aisya; Kurniati, Yuni Prastyo
Journal La Medihealtico Vol. 5 No. 5 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i5.1616

Abstract

Bone tumour is a term for a group of tumours located in the bones. World Health Organization data in 2020 stated that the incidence rate of bone sarcoma in the Americas and Europe was 0.8 per 100,000 population. Industrial development, especially in areas with high population density, has environmental impacts such as air pollution and contamination of water sources. This has been associated with an increase in the prevalence of bone tumours in children. However, studies on this matter are still limited. This study aims to analyze the effect of industrial areas and age factors on the level of bone tumour malignancy. This study used observational analytics with a case-control design. Osteosarcoma as the case variable and GCT as the control variable. The sample used was 106, consisting of 53 osteosarcoma tumours and 53 GCT tumours. Age classification is divided into 0-18 years and 319 years. Industrial area classification is divided into <2.5 km and 32.5 km. Bivariate analysis using the chi square test. Has obtained approval from the Health Research Ethics Commission (KEPK) of RSUD dr. Moewardi with Number: 1.557/VI/HREC/2024. Results found no significant effect of age factor on the level of bone tumour malignancy (p-value=0.204). Meanwhile, an insignificant effect was also found between the proximity of residence to industrial areas on the level of bone tumour malignancy (p-value=0.121). This study shows that age factor and proximity of residence to industrial areas do not affect the level of bone tumour malignancy.
Edukasi Literasi Kesehatan Reproduksi tentang Manajemen Preventif Leukorhea pada Santriwati: Reproductive Health Literacy Education about Preventive Management of Leukorrhea in Female Students Kurniati, Yuni Prastyo; Romadhon, Yusuf Alam; Futana, Ninda Pradani; Rosyita, Fadhilla Jihan; Farma, Aufa Faza Fauzan; Latifah, Lisanul
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 5 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i5.6688

Abstract

Teenager is an age group that is in a transitional period of human development. The transition period is the process of biological maturation into adults who can reproduce sexually and has the potential for all the consequences of sexual activity. Vaginal discharge is a problem that is often encountered after women experience puberty and may indicate a normal phenomenon, an infection, or other conditions. Healthy, clean-living behavior related to reproductive health in teenagers has a significant correlation with the level of knowledge and daily behavior of teenagers that affect leukorrhea. To increase the awareness of female students at the Modern Assalam Islamic Boarding School regarding clean and healthy living behavior in the field of healthy female reproduction system with support from health professionals and preventive education on leucorrhoea. This service activity was conducted with a total of 60 participants who were involved in filling out the pretest and post-test. The activity phase included initial studies through student-teacher discussions, preparation of learning materials and evaluation methods, and implementation of learning activities and evaluations. A total of 60 female students who took part in this reproductive health education activity got a preventive education knowledge, proved by comparing the pretest scores before the health education activity was carried out and the post-test after the educational activity. A significant increase was obtained with a rate of 93%. Activities related to leucorrhoea in female students show the effectiveness of significant improvement in the knowledge and enthusiasm of the participants.
Usia sebagai Faktor Risiko dari Tumor Ganas Osteosarkoma Friska Desi Sabita; Yuni Prastyo Kurniati
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 4 (2024): Oktober-Desember 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15404

Abstract

Osteosarcoma is an invasive bone tumor malignancy, grows aggressively and has a high mortality rate. One of the risk factors for this cancer is age. On the other hand, industrial areas increase the risk of this disease. The purpose of this study was to analyze age and proximity to industrial areas as risk factors for osteosarcoma. This study used a case-control design. Osteosarcoma was the case group and Giant Cell Tumor of Bone was the control group. A total of 142 samples were taken from medical records of bone tumor histopathology preparations at the Pathology Anatomy Laboratory, Faculty of Medicine, UMS using the purposive sampling method. The age variable was divided into groups of 0-18 years and >18 years. The cut-off point for the distance to the industrial area was 2.5 km. The measurement data of the variables were analyzed using the Chi-square test. The results of the study showed an effect of age on the incidence of osteosarcoma (p value = 0.01); but there was no effect of distance to the industrial area on the incidence of osteosarcoma (p value = 0.369). The conclusion of the study shows that age is a risk factor for osteosarcoma.Keywords: osteosarcoma; age; risk factors ABSTRAK Osteosarkoma adalah keganasan tumor tulang yang bersifat invasif, berkembang secara agresif serta memiliki tingkat mortalitas yang tinggi. Salah satu faktor risiko dari kanker ini adalah usia. Di sisi lain, kawasan industri meningkatkan risiko penyakit ini. Tujuan penelitian ini adalah menganalisis usia dan kedekatan kawasan industri sebagai faktor risko kejadian osteosarkoma. Penelitian ini menggunakan desain case-control. Osteosarkoma merupakan kelompok kasus dan Giant Cell Tumor of Bone merupakan kelompok kontrol. Sejumlah 142 sampel diambil dari rekam medis sediaan histopatologi tumor tulang di Laboratorium Patologi Anatomi FK UMS dengan metode purposive sampling. Variabel usia terbagi menjadi kelompok 0-18 tahun dan >18 tahun. Cut off poin jarak terhadap kawasan industri adalah 2,5 km. Data hasil pengukuran variabel dianalisis menggunakan uji Chi-square. Hasil penelitian menunjukkan adanya pengaruh usia terhadap kejadian osteosarkoma (nilai p = 0,01); namun tidak ada pengaruh jarak dengan kawasan industri terhadap kejadian osteosarkoma (nilai p = 0,369). Kesimpulan penelitian menunjukkan bahwa usia merupakan faktor risiko osteosarkoma.Kata kunci: osteosarkoma; usia; faktor risiko
The Influence of Agricultural Environment on Inflammation and Breast Cancer: A Systematic Review Abdussalam, Arrizqi Hafidh; Permatasari, Happy Kurnia; Sutrisna, EM.; Romadhon, Yusuf Alam; Kurniati, Yuni Prastyo
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5493

Abstract

Purpose: Analyzing the influence of agricultural environment on inflammation and breast cancer. Methodology: PECOS by mentioning terms in MeSH as search keywords. Inclusion criteria include: observational cohort, cross sectional or case control study design. Exclusion criteria included various forms of reviews, experimental design studies, RCTs and in animals, in-vitro studies and in-silico studies. Results: Google Scholar platform search obtained 112 articles and 177 articles from the Scopus database. After identification and screening using PRISMA-P, 6 articles were obtained. Benign and malignant breast lesions were significantly associated with exposure to environmental estrogens including polychlorinated biphenyls (PCBs) and organochlorines. There was an increase in inflammatory biomarkers, namely NF-κB, PPAR-γ, IL-12 dan TNF-α levels in breast lesions from areas with high pesticide spending. Applications: The agricultural environment is a risk factor for breast cancer mediated by inflammatory factors.
Relationship between Obesity and Location of Residence with The Incidence of Fibroadenoma Mammae Povitasari, P; Kurniati, Yuni Prastyo; Lestari, Nining; Mahmudah, Nur
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5531

Abstract

Purpose: Fibroadenoma mammae (FAM) is a common benign breast tumor predominantly affecting young women. While obesity and location of residence are thought to influence the risk of FAM, evidence remains inconclusive. The aim to analyze the relationship between obesity, location of residence, and the incidence of FAM in Central Java, Indonesia. Methodology: This observational analytical study employed a case-control design using retrospective medical record data. The study included patients with breast tumors who underwent surgery and histopathological examination. Patients were categorized into the FAM group (cases) and non-FAM group (controls). Data on body mass index (BMI) and location of residence (urban or rural) were analyzed to determine their relationship with FAM. Results: The study revealed that FAM patients had a significantly younger median age compared to non-FAM patients (30 vs. 36 years; p = 0.015). Obesity was significantly less common in FAM patients than non-FAM patients (p = 0.001), with obese individuals having a 0.2 times lower risk of developing FAM (OR = 0.2). There was no significant association between location of residence and FAM incidence (p = 1.000; OR = 1.0). Applications/Originality/Value: There is a relationship between obesity status and the incidence of FAM. Obese women have a 0.2 times lower risk of experiencing FAM than non-obese study subjects, it can be considered that obesity is a protective factor against the occurrence of FAM. There is no relationship between location of residence and the incidence of FAM.
An An Analysis Of The Incidence Of Sensorinural Hearing Loss Based On Type 2 Diabetes Mellitus And Obesity Factor: An Analysis Of The Incidence Of Sensorinural Hearing Loss Based On Type 2 Diabetes Mellitus And Obesity Factor Dilla, Natasya Salsa; Wirayudha, Yan; Kurniati, Yuni Prastyo; Soekiswati, Siti
Journal of Agromedicine and Medical Sciences Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i2.53711

Abstract

Indonesia ranks fourth in Southeast Asia with a 2.3% prevalence of sensorineural hearing loss, a condition that may result from various risk factors including diabetes mellitus (DM) and obesity. DM can impair cochlear vascularization, while obesity significantly affects vascular function, potentially impacting the auditory system. This study aims to analyze the relationship between type 2 DM and obesity with sensorineural hearing loss. An observational analytic study with a cross-sectional approach was conducted on 64 participants aged 18–60 years, selected via purposive sampling. Type 2 DM was diagnosed by internal medicine consultants, and obesity was assessed using waist-to-hip ratio measurements. Data analysis employed Fisher's exact test and logistic regression. The study was ethically approved by the Health Ethics Committee of RS PKU Muhammadiyah Surakarta (No. 05/KEPK/RS.PKU/X/2024). Results showed a significant correlation between type 2 DM and sensorineural hearing loss (p=0.037) and between obesity and sensorineural hearing loss (p=0.001). The odds ratio for type 2 DM was 12.031, while for obesity it was 58.059, indicating that obesity poses a substantially higher risk. In conclusion, type 2 DM and obesity are significantly associated with the occurrence of sensorineural hearing loss, suggesting that addressing these risk factors may help reduce its prevalence. Keywords: Diabetes Melitus Tipe 2, Obesitas, Gangguan Pendengaran Sensorineural, Faktor Risiko.