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All Journal Jurnal Riset Kesehatan Journal of Agromedicine and Medical Sciences Medical Laboratory Technology Journal Herb-Medicine Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Medika Malahayati PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Kesehatan Jurnal Ners JOURNAL LA MEDIHEALTICO Proceeding ISETH (International Summit on Science, Technology, and Humanity) Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika International Journal of Health Science and Technology JHeS (Journal of Health Studies) Journal of Health Sciences and Medical Development
Yuni Prastyo Kurniati
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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The Role of Menarcheal Age and Parity in the Development of Uterine Leiomyoma Elvina Fawwaz Maharizdihar; Yuni Prastyo Kurniati
Journal of Health Sciences and Medical Development Vol. 4 No. 03 (2025): Forthcoming Issue - Journal of Health Sciences and Medical Development
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/hesmed.v4i03.1415

Abstract

Uterine leiomyoma is the most prevalent benign neoplasm of the female reproductive tract during the reproductive years; however, its precise etiology remains incompletely understood. Age at menarche and parity have been proposed as potential risk factors, although previous studies have reported inconsistent findings. This study aimed to evaluate the association between age at menarche and parity with the occurrence of uterine leiomyoma. This research employed a case-control design, in which uterine leiomyoma constituted the case group and adenomyosis served as the control group, conducted at PKU Muhammadiyah Hospital Surakarta. The study included 113 participants, comprising 73 cases of uterine leiomyoma and 40 cases of adenomyosis as controls, identified through histopathological records from 2023. Data were assessed using Chi-Square and logistic regression analyses. The findings revealed that most respondents experienced menarche at a normal age and were either primiparous or multiparous. Statistical testing demonstrated a significant association between age at menarche (p = 0.007; OR = 1.65, 95% CI = 1.414–1.939) and the incidence of uterine leiomyoma, whereas parity was not significantly associated (p = 0.384; OR = 1.509, 95% CI = 0.596–3.825). Future studies are recommended to include more balanced sample group proportions and additional risk factors to obtain a more comprehensive understanding of uterine leiomyoma etiology.
Co-Authors Abdussalam, Arrizqi Hafidh Alfajri, Asri Almansyah, Wanda Emdia Anika Candrasari Annisa, Celina Rizki Annisa, Valda Yulia Arismar, Fiqi Rahardian Aryati, Mandarini Dwi Putri Azizah Fatmawati Berliana, Sabna Ayu Sagita Celina Rizki Annisa Devi, Namira Aisya Dilla, Natasya Salsa Elvina Fawwaz Maharizdihar Em Sutrisna Faricha Kurnia Illahi Farma, Aufa Faza Fauzan Fathanita, Abiyya Firdausi, Nida Faradisa Futana, Ninda Pradani Gymnastiar, Ashar Handayani, Alya Nurkinasih Putri Happy Kurnia Permatasari Hilyati, Nor Ilmin Nafiah Islamuddin, Tri Kurnia Ahmad Khonsa, Khonsa Latifah, Lisanul Lestari, Nining Meliani, Reza Ika Muhammad Adnan N. Juni Triastuti Nabilah, Aisyah Nafiah, Ilmin Nugraheni, Fladea Eka Nur Mahmudah Paramarta, Nugrahani Putri Tyas Parawansa, Karmila Indar Parawansa Povitasari, P Presmasitha, Bricareira Bara Raharja, Supanji Ratih Pramuningtyas Retno Sintowati - Reza Ika Meliani Rosyita, Fadhilla Jihan Sahilah Ermawati Salsabila, Naura Siti Soekiswati Sri Wahyuni Supanji Raharja Tri Agustina Tri Kurnia Ahmad Islamuddin Tuanaya, Muhammad Rizqy Noer Valda Yulia Annisa Wibowo, Wahyu Aji Wirayudha, Yan Yunandar, Rio Yusuf Alam Romadhon Zahro, Ikhya' Izatus