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Kejadian Benign Prostatic Hyperplasia Berdasarkan Faktor Kadar Limfosit dan Tempat Tinggal Bricareira Bara Presmasitha; Yuni Prastyo Kurniati; Nur Mahmudah; N. Juni Triastuti
Jurnal Ners Vol. 9 No. 3 (2025): JULI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.46981

Abstract

Benign prostatic hyperplasia (BPH) is a usually abnormality in elderly men. This study aims to explain the influence between residence factors and lymphocyte levels on the incidence of BPH. This study used an analytic observational research design with a cross sectional approach. The population in this study were medical records of histopathology preparations at the PA Laboratory of PKU Muhammadiyah Surakarta Hospital. The sample in this study was medical records of histopathology preparations with a diagnosis of prostate tumor from 2021 to 2024 using the principle technique of total sampling. The research instruments used in this study were laboratory medical records and medical record units at PKU Muhammadiyah Surakarta Hospital. Data analysis techniques in this study include univariate analysis, bivariate analysis using the Chi Square test, and multivariate test using logistic regression test. The results of this study found that there is a significant influence between residence factors and the incidence of benign prostate hyperplasia (P=0.02; OR=7.00). There is no significant correlation between lymphocyte level (%) and the incidence of benign prostate hyperplasia (P=0.040; OR=0,957). The residence variable has a greater influence on the incidence of benign prostate hyperplasia than the lymphocyte level factor.
The Role of Menarcheal Age and Parity in the Development of Uterine Leiomyoma Elvina Fawwaz Maharizdihar; Yuni Prastyo Kurniati
Journal of Health Sciences and Medical Development Vol. 4 No. 03 (2025): Journal of Health Sciences and Medical Development
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/hesmed.v4i03.1415

Abstract

Uterine leiomyoma is the most prevalent benign neoplasm of the female reproductive tract during the reproductive years; however, its precise etiology remains incompletely understood. Age at menarche and parity have been proposed as potential risk factors, although previous studies have reported inconsistent findings. This study aimed to evaluate the association between age at menarche and parity with the occurrence of uterine leiomyoma. This research employed a case-control design, in which uterine leiomyoma constituted the case group and adenomyosis served as the control group, conducted at PKU Muhammadiyah Hospital Surakarta. The study included 113 participants, comprising 73 cases of uterine leiomyoma and 40 cases of adenomyosis as controls, identified through histopathological records from 2023. Data were assessed using Chi-Square and logistic regression analyses. The findings revealed that most respondents experienced menarche at a normal age and were either primiparous or multiparous. Statistical testing demonstrated a significant association between age at menarche (p = 0.007; OR = 1.65, 95% CI = 1.414–1.939) and the incidence of uterine leiomyoma, whereas parity was not significantly associated (p = 0.384; OR = 1.509, 95% CI = 0.596–3.825). Future studies are recommended to include more balanced sample group proportions and additional risk factors to obtain a more comprehensive understanding of uterine leiomyoma etiology.
Analysis of Age Factor and Hemoglobin Profiles in The Incidence of Uterine Leiomyoma Nugrahani Putri Tyas Paramarta; Yuni Prastyo Kurniati
Jurnal Kesehatan Vol 16 No 3 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i3.5393

Abstract

Uterine leiomyoma is recognized as the most common benign tumor of the female reproductive system and remains a significant cause of gynecological morbidity worldwide. Its development has been closely associated with hormonal exposure, particularly estrogen and progesterone, and with reproductive age. Despite being frequently encountered in clinical practice, the role of other contributing factors, such as hemoglobin status, remains less clear. This study examined the relationships among age, hemoglobin concentration, and the incidence of uterine leiomyoma. An observational-analytic case-control design, using leiomyoma as cases and adenomyosis as controls, was conducted at PKU Muhammadiyah Hospital, Surakarta. A total of 246 participants were included, comprising 93 women with histopathologically confirmed leiomyoma and 153 women with adenomyosis as the control group. Data were obtained from hospital medical records, and statistical analyses were performed using Chi-square tests followed by logistic regression. The results demonstrated that being in the reproductive age group (≤50 years) significantly increased the likelihood of leiomyoma occurrence (OR=3.114, 95%CI: 1.141–8.500, p=0.021). In contrast, hemoglobin profiles did not show a significant association with leiomyoma incidence (OR=0.777, 95%CI: 0.428–1.441, p=0.407). Although anemia was frequently observed in both groups, it appeared more likely to be a clinical manifestation of abnormal uterine bleeding than a direct etiological factor.
Analysis of Prostate Cancer Incidence Based on Body Mass Index and Blood Pressure Factors Sabna Ayu Sagita Berliana; Yuni Prastyo Kurniati
Journal La Medihealtico Vol. 6 No. 5 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i5.2724

Abstract

Prostate cancer is one of the most common cancers in men worldwide and ranks fourth according to GLOBOCAN 2022. Its incidence in Asia, including Indonesia, continues to increase each year. Prostate cancer risk factors include both modifiable variables like blood pressure and body mass index (BMI) and non-modifiable variables like age and family history. This study aimed to determine the association between BMI and blood pressure with the incidence of prostate cancer. This study employed an analytical observational design using a retrospective hospital-based case-control approach. A total of 68 samples were collected, comprising 22 patients with benign prostatic hyperplasia (BPH) as the control group and 46 patients with prostate cancer as the case group. BMI and blood pressure data were collected from medical records and categorized based on the classifications from the WHO and PERHI (2019). The chi-square test was employed for the bivariate analysis with a significance level of p < 0.05. There was no significant associationfound between blood pressure and the incidence of prostate cancer (p = 0.304), while there was a significant association between BMI and the risk of prostate cancer (p = 0.023). The OR value of 0.581 with a 95% CI (0.205–1.645) indicated that blood pressure was not a statistically significant factor. These findings imply that hormonal alterations, persistent inflammation, and elevated insulin-like growth factor 1 (IGF-1) activity may raise the risk of prostate cancer in overweight individuals. In conclusion, BMI shows a significant association with prostate cancer incidence, whereas blood pressure does not demonstrate a significant association.
Hubungan antara Penggunaan Jenis Kontrasepsi Hormonal dan Gaya Hidup terhadap Kejadian Obesitas pada Akseptor KB Hormonal Laila Cahya Ratnasari; Siti Soekiswati; Nining Lestari; Yuni Prastyo Kurniati
Proceeding Book Call for Papers Fakultas Kedokteran Universitas Muhammadiyah Surakarta 2023: Proceeding Book Call for Papers Fakultas Kedokteran Universitas Muhammadiyah Surakarta (Thalam
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

Obesitas menciptakan kematian penduduk di berbagai negara lebih tinggi dibandingkan yang memiliki berat badan kurang. Prevalensi wanita yang mengalami obesitas di Indonesia mencapai angka 44,4% di tahun 2018. Obesitas pada wanita selain menurunkan estetika juga dapat meningkatkan risiko penyakit seperti dislipidemia, penyakit jantung, diabetes melitus tipe 2, dan lain sebagainya. Berbagai komplikasi tersebut dapat terjadi sebagai akibat dari penggunaan kontrasepsi hormonal dan gaya hidup yang buruk pada wanita akseptor KB hormonal. Sehingga sangat penting bagi wanita untuk mempertimbangkan jenis kontrasepsi dan pengaruh penggunaannya. Tujuan penelitian ini untuk menganalisis hubungan antara penggunaan jenis kontrasepsi hormonal dan gaya hidup terhadap kejadian obesitas pada akseptor KB hormonal. Penelitian ini bersifat observasional analitik dengan pendekatan cross sectional. Teknik sampling yang digunakan dalam adalah purposive sampling. Pengambilan sampel yang dibutuhkan yaitu sebanyak 128 responden yang memenuhi kriteria restriksi. Teknik pengambilan data primer dengan menggunakan kuesioner dan perhitungan IMT. Analisis bivariat jenis kontrasepsi hormonal dengan kejadian obesitas memiliki p-value 0,109. Hasil p-value dari gaya hidup dengan kejadian obesitas memiliki nilai 0,778. Sehingga, analisis multivariat tidak dapat dilakukan. Tidak terdapat hubungan yang bermakna antara penggunaan jenis kontrasepsi hormonal dan gaya hidup dengan kejadian obesitas akseptor KB hormonal.
Hubungan Tingkat Pendidikan, Status Gizi, dan Kepatuhan Mengonsumsi Tablet Fe dengan Kejadian Anemia pada Ibu Hamil Aisyawa Sabrina Aaliyah Sanyoto; Saidatul Fithriyah; Tri Agustina; Yuni Prastyo Kurniati
Proceeding Book Call for Papers Fakultas Kedokteran Universitas Muhammadiyah Surakarta 2023: Proceeding Book Call for Papers Fakultas Kedokteran Universitas Muhammadiyah Surakarta (Thalam
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

Latar Belakang: Anemia pada kehamilan menyebabkan keguguran, lahir prematur, lamanya durasi persalinan, pendarahan postpartum, serta rentan peradangan. Data Riset Kesehatan Dasar (Riskesdas) 2018 menunjukkan prevalensi anemia ibu hamil di Indonesia sebanyak 48,9%. Tingkat pendidikan bisa menentukan wawasan seseorang karena kemampuan seseorang dalam menguasai dan menerima sesuatu dipengaruhi oleh tingkat pendidikan yang dimilikinya. Status gizi ibu yang buruk dapat berakibat tidak baik bagi ibu dan janin. Tablet Fe yang dikonsumsi setiap hari dapat menurunkan prevalensi anemia serta mencegah timbulnya anemia. Tujuan: Untuk menganalisis hubungan tingkat pendidikan, status gizi, dan kepatuhan mengonsumsi tablet Fe dengan kejadian anemia pada ibu hamil. Metod : Observasional analitik dengan pendekatan cross sectional serta purposive random sampling sebanyak 35 responden. Hasil: Analisis bivariat antara tingkat pendidikan dengan anemia pada ibu hamil memiliki p-value senilai 0,003. Hasil p-value dari status gizi dengan anemia pada ibu hamil senilai 0,410. Hasil p-value dari kepatuhan mengonsumsi tablet Fe dengan anemia pada ibu hamil senilai 0,229. Kesimpulan: Terdapat hubungan antara tingkat pendidikan dengan kejadian anemia pada ibu hamil, tetapi tidak terdapat hubungan antara status gizi dan kepatuhan mengonsumsi tablet Fe dengan kejadian anemia pada ibu hamil.