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Analysis of Age Factor and Hemoglobin Profiles in The Incidence of Uterine Leiomyoma Paramarta, Nugrahani Putri Tyas; Kurniati, Yuni Prastyo
Jurnal Kesehatan Vol 16 No 3 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i3.5393

Abstract

Uterine leiomyoma is recognized as the most common benign tumor of the female reproductive system and remains a significant cause of gynecological morbidity worldwide. Its development has been closely associated with hormonal exposure, particularly estrogen and progesterone, and with reproductive age. Despite being frequently encountered in clinical practice, the role of other contributing factors, such as hemoglobin status, remains less clear. This study examined the relationships among age, hemoglobin concentration, and the incidence of uterine leiomyoma. An observational-analytic case-control design, using leiomyoma as cases and adenomyosis as controls, was conducted at PKU Muhammadiyah Hospital, Surakarta. A total of 246 participants were included, comprising 93 women with histopathologically confirmed leiomyoma and 153 women with adenomyosis as the control group. Data were obtained from hospital medical records, and statistical analyses were performed using Chi-square tests followed by logistic regression. The results demonstrated that being in the reproductive age group (≤50 years) significantly increased the likelihood of leiomyoma occurrence (OR=3.114, 95%CI: 1.141–8.500, p=0.021). In contrast, hemoglobin profiles did not show a significant association with leiomyoma incidence (OR=0.777, 95%CI: 0.428–1.441, p=0.407). Although anemia was frequently observed in both groups, it appeared more likely to be a clinical manifestation of abnormal uterine bleeding than a direct etiological factor.
STUDI KASUS-KONTROL: FAKTOR RISIKO ADENOMIOSIS PADA WANITA USIA REPRODUKSI DALAM KAITANNYA DENGAN TEKANAN DARAH DAN INDEKS MASSA TUBUH Gymnastiar, Ashar; Kurniati, Yuni Prastyo
Jurnal Riset Kesehatan Vol 14 No 2 (2025): NOVEMBER 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v14i2.13995

Abstract

Adenomyosis is a benign uterine condition characterized by the presence of endometrial tissue within the myometrium. This study aimed to analyze the association between blood pressure and body mass index with the incidence of adenomyosis. This study employed a case control design, in which the case group comprised patients diagnosed with adenomyosis, while the control group consisted of patients with uterine leiomyoma. The research was conducted at PKU Muhammadiyah Hospital Surakarta. A total of 221 medical record samples were collected using purposive sampling from 2020 to 2024, consisting of 130 cases of adenomyosis and 91 controls of uterine leiomyoma. Clinical variables including blood pressure, body mass index, age, parity, and residence were assessed. Data analysis was performed using Chi-Square tests. The results showed a significant association between blood pressure and the incidence of adenomyosis, with hypertensive women having a 2.7-fold higher risk of adenomyosis compared to normotensive women. In contrast, there was no significant association between body mass index and adenomyosis. In conclusion, the findings suggest that hypertension is a more prominent risk factor than obesity in the development of adenomyosis. Future studies involving to enhance preventive strategies and optimize clinical management.
Kejadian Benign Prostatic Hyperplasia Berdasarkan Faktor Kadar Limfosit dan Tempat Tinggal Bricareira Bara Presmasitha; Yuni Prastyo Kurniati; Nur Mahmudah; N. Juni Triastuti
Jurnal Ners Vol. 9 No. 3 (2025): JULI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.46981

Abstract

Benign prostatic hyperplasia (BPH) is a usually abnormality in elderly men. This study aims to explain the influence between residence factors and lymphocyte levels on the incidence of BPH. This study used an analytic observational research design with a cross sectional approach. The population in this study were medical records of histopathology preparations at the PA Laboratory of PKU Muhammadiyah Surakarta Hospital. The sample in this study was medical records of histopathology preparations with a diagnosis of prostate tumor from 2021 to 2024 using the principle technique of total sampling. The research instruments used in this study were laboratory medical records and medical record units at PKU Muhammadiyah Surakarta Hospital. Data analysis techniques in this study include univariate analysis, bivariate analysis using the Chi Square test, and multivariate test using logistic regression test. The results of this study found that there is a significant influence between residence factors and the incidence of benign prostate hyperplasia (P=0.02; OR=7.00). There is no significant correlation between lymphocyte level (%) and the incidence of benign prostate hyperplasia (P=0.040; OR=0,957). The residence variable has a greater influence on the incidence of benign prostate hyperplasia than the lymphocyte level factor.
The Role of Menarcheal Age and Parity in the Development of Uterine Leiomyoma Elvina Fawwaz Maharizdihar; Yuni Prastyo Kurniati
Journal of Health Sciences and Medical Development Vol. 4 No. 03 (2025): Journal of Health Sciences and Medical Development
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/hesmed.v4i03.1415

Abstract

Uterine leiomyoma is the most prevalent benign neoplasm of the female reproductive tract during the reproductive years; however, its precise etiology remains incompletely understood. Age at menarche and parity have been proposed as potential risk factors, although previous studies have reported inconsistent findings. This study aimed to evaluate the association between age at menarche and parity with the occurrence of uterine leiomyoma. This research employed a case-control design, in which uterine leiomyoma constituted the case group and adenomyosis served as the control group, conducted at PKU Muhammadiyah Hospital Surakarta. The study included 113 participants, comprising 73 cases of uterine leiomyoma and 40 cases of adenomyosis as controls, identified through histopathological records from 2023. Data were assessed using Chi-Square and logistic regression analyses. The findings revealed that most respondents experienced menarche at a normal age and were either primiparous or multiparous. Statistical testing demonstrated a significant association between age at menarche (p = 0.007; OR = 1.65, 95% CI = 1.414–1.939) and the incidence of uterine leiomyoma, whereas parity was not significantly associated (p = 0.384; OR = 1.509, 95% CI = 0.596–3.825). Future studies are recommended to include more balanced sample group proportions and additional risk factors to obtain a more comprehensive understanding of uterine leiomyoma etiology.