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All Journal Jurnal Riset Kesehatan Journal of Agromedicine and Medical Sciences Medical Laboratory Technology Journal Herb-Medicine Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Medika Malahayati PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Kesehatan Jurnal Ners JOURNAL LA MEDIHEALTICO Proceeding ISETH (International Summit on Science, Technology, and Humanity) Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika International Journal of Health Science and Technology JHeS (Journal of Health Studies) Journal of Health Sciences and Medical Development
Yuni Prastyo Kurniati
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Distribusi Benign Soft Tissue Tumor berdasarkan Gender dan Usia Islamuddin, Tri Kurnia Ahmad; Kurniati, Yuni Prastyo
Prosiding University Research Colloquium Proceeding of The 15th University Research Colloquium 2022: Mahasiswa (Student Paper Presentation) A
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Soft tissue tumor is a disorder that occurs in non-epithelial tissue including fatty tissue, fibrous tissue, neurovascular tissue and muscle tissue. This disease is more common in women than men. While the age that is often diagnosed with this lesion is found in the age range of 15-25 years and 35-54 years. This study aims to analyze whether there is an influence between gender and age with the distribution of benign soft tissue tumors. This study uses a cross sectional study with a retrospective approach. The research sample was histopathological preparations taken from 161 patients with medical record data according to the inclusion criteria. Sampling using purposive sampling technique. Data were analyzed using fisher test. Based on gender, the highest frequency of samples was female as much as 51.6%. Based on age, it was found more in the age range of 17-25 years. The results of the chi-square test of the effect of gender on the distribution of benign soft tissue tumors showed p 1.000, while the effect of age on the distribution of benign soft tissue tumors showed p 0.407. There is no significant effect between the distribution of benign soft tissue tumors on gender and age.
Pengaruh Tingkat Pendidikan terhadap Pengetahuan dan Sikap Ibu Tentang Papsmear sebagai Upaya Deteksi Dini Kanker Serviks Kurniati, Yuni Prastyo; Meliani, Reza Ika
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Kanker serviks merupakan penyebab kematian utama kanker pada wanita di dunia. Faktor yang mempengaruhi terjadinya kanker serviks yaitu para ibu sering enggan untuk memeriksakan diri, disebabkan masih rendahnya tingkat pendidikan dan pengetahuan masyarakat serta ketiadaan biaya. Pap smear dapat mendeteksi kanker serviks dengan hasil yang akurat mencapai 90% dan spesifitas 90%-95. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh tingkat pendidikan terhadap pengetahuan dan sikap ibu tentang pap smear sebagai upaya deteksi dini kanker serviks. Metode penelitian ini menggunakan desain penelitian cross sectional. Subjek penelitian adalah 148 responden yang diambil dengan teknik purposive sampling. Pengambilan data menggunakan kuesioner melalui google form yang tautannya dibagikan melalui aplikasi WhatsApp. Data dianalisis menggunakan uji chi-square dan regresi logistik. Hasil analisis uji regresi logistik pengaruh tingkat pendidikan terhadap pengetahuan didapatkan nilai OR exp. B sebesar 0.441. Uji regresi logistik pengaruh tingkat pendidikan terhadap sikap didapatkan nilai OR exp. B sebesar 7.459. Dari hasil penelitian dapat disimpulkan bahwa terdapat pengaruh tingkat pendidikan terhadap pengetahuan dan sikap ibu tentang pap smear
Pengaruh rokok pada tekanan darah, indeks masa tubuh dan rasio lingkar pinggang / panggul (sebuah studi observasional di Indonesia) Romadhon, Yusuf Alam; Kurniati, Yuni Prastyo
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Pendahuluan: penyakit kardiovaskuler telah menjadi masalah kesehatan global dan nasional, dimana hipertensi dan obesitas menjadi factor contributor utama. Rokok di Indonesia masih menjadi lima besar komoditas belanja rumah tangga. Belum banyak digali bagaimana pengaruh rokok terhadap tekanan darah dan obesitas. Tujuan: mengevaluasi pengaruh rokok terhadap tekanan darah, indeks masa tubuh dan rasio lingkar pinggang / panggul. Metode: studi potong lintang yang melibatkan anggota keluarga / tetangga dekat mahasiswa FKUMS dalam program Field Lab dengan tetap menegakkan protocol kesehatan di bulan November 2020. Data yang dikumpulkan meliputi data demografi, antropometri dan tekanan darah. Hasil: sebanyak 435 responden secara sukarela mengikuti penelitian ini. Dari analisis bivariat didapatkan rerata [SD] tekanan darah sistolik, diastolic, indeks masa tubuh dan rasio lingkar pinggang/panggul antara perokok vs non-perokok secara berurutan: 125.06[15.31] vs 118.92 [14.51] mmHg; p=0.000; 83.11[8.91]vs80.01[9.65] mmHg; p=0.010; 24.81[3.88] vs 23.95[4.16] kg/m2; p=0.106; 0.92[0.09] vs 0.89[0.08]; p=0.001. Simpulan: merokok berpengaruh dalam meningkatkan tekanan darah sistolik dan diastolic serta rasio lingkar pinggang/panggul, tetapi tidak dengan indeks masa tubuh.
STUDI KASUS LANGKA : BARRETS ESOFAGUS USIA MUDA Kurniati, Yuni Prastyo; Wibowo, Wahyu Aji
Prosiding University Research Colloquium Proceeding of The 19th University Research Colloquium 2024: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Pendahuluan : Barrett Esofagus dapat berkembang menjadi Adenokarsinoma Esofagus/EAC. Kanker dengan insiden yang meningkat cepat dan berlangsung buruk. Kanker ganas ini bertambah pesat di Amerika Serikat dan negara lain. Namun, sebagian besar kasus terdeteksi terlambat, dengan tingkat kematian 90%. Barrett Esofagus merupakan satu-satunya prekursor EAC. Transformasi bermula dari displasia tingkat rendah, ke tingkat tinggi kemudian berkembang sebagai EAC. Beberapa riset melaporkan perkembangan lesi ini menjadi kanker esofagus semakin meningkat di Asia seiring dengan meningkatnya prevalensi BE dan sebagian besar pada usia >70 tahun. Studi lesi ini masih sangat jarang dilakukan di seluruh dunia, termasuk di Indonesia. Sehingga kasus ini merupakan temuan unik, langka dan berharga. Tujuan: Melaporkan dua kasus langka tentang Barretts Esofagus pada usia muda. Metode: Studi kasus menggunakan pendekatan klinis dan tinjauan pustaka dari Ilmu Penyakit dalam dan Patologi Anatomi. Hasil : dua kasus berasal dari laki-laki, usia 26 tahun dan 33 tahun, dengan keluhan kolik abdomen dan ulu hati terasa panas, yang menjalar hingga ke atas sehingga leher seperti tercekik. Diagnosa klinis awal mengarah pada suspek cancer Gaster dan Tumor Gastro esofageal junction. Kemudian dilakukan pemeriksaan Endoskopi sebagai pendekatan diagnosis oleh ahli Penyakit Dalam. Endoskopi memperlihatkan Esofagus tampak hiperemis dengan break lebih dari 5 mm, terdapat massa yang berbenjol-benjol serta rapuh. Tonus Lower spinchter esofageal mulai menurun, namun tak terlihat varises. Hasil Endoskopi menyebutkan Esofagitis dengan tumor Gastro Esofageal Junction. Massa tersebut dilakukan biopsi dan dilanjutkan Pemeriksaan Patologi Anatomi. Gambaran Mikroskopis mendapatkan keping jaringan dengan mukosa berlapiskan epitel squamous kompleks, sebagian erosif. Diantaranya ditemukan area mukosa yang mengalami metaplasia intestinal. Daerah submucosa mengandung kelenjar berstruktur tubular hingga berkelok dengan dinding berlapiskan epitel kolumner bergoblet. Tak ditemukan sel ganas. Hasil ini sesuai dengan Barretts Esofagus. Kesimpulan : Kasus ini memperbanyak pengetahuan dan informasi kasus langka tentang barretts Esofagus pada Usia muda.
Penguatan Kapasitas Kader Posyandu melalui Edukasi Gizi dan Penanganan Gerakan Tutup Mulut untuk Pencegahan Stunting di Desa Trangsan, Sukoharjo: Strengthening the Capacity of Posyandu Cadres through Nutrition Education and Food Refusal Management for Stunting Prevention in Trangsan Village, Sukoharjo Romadhon, Yusuf Alam; Candrasari, Anika; Fatmawati, Azizah; Kurniati, Yuni Prastyo; Adnan, Muhammad; Hilyati, Nor
Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jppmi.v4i2.868

Abstract

Stunting masih menjadi masalah kesehatan masyarakat di Indonesia dengan prevalensi tinggi pada anak balita dan penurunan yang relatif lambat. Faktor penyebab mencakup gizi buruk, infeksi berulang, rendahnya pendidikan, kondisi sosial ekonomi, serta keterbatasan akses layanan kesehatan. Di Kecamatan Gatak, Sukoharjo, masalah stunting juga dipengaruhi oleh perilaku makan anak, termasuk fenomena Gerakan Tutup Mulut (GTM) yang berdampak pada status gizi dan tumbuh kembang balita. Kader posyandu memiliki peran strategis dalam deteksi dini dan pendampingan keluarga melalui edukasi serta konseling. Program pengabdian masyarakat di Desa Trangsan dilakukan dengan pelatihan pengukuran antropometri, edukasi status gizi, serta strategi penanganan GTM, diikuti oleh 31 kader posyandu. Hasil evaluasi menunjukkan peningkatan signifikan pengetahuan kader: pada tema status gizi nilai rata-rata meningkat dari 80,00 menjadi 90,32 (p=0,007), dan pada tema GTM dari 60,00 menjadi 87,74 (p=0,000). Pelatihan ini terbukti efektif meningkatkan kapasitas kader posyandu sebagai garda terdepan pencegahan stunting di masyarakat.
Analysis of Prostate Cancer Incidence Based on Body Mass Index and Blood Pressure Factors Berliana, Sabna Ayu Sagita; Kurniati, Yuni Prastyo
Journal La Medihealtico Vol. 6 No. 5 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i5.2724

Abstract

Prostate cancer is one of the most common cancers in men worldwide and ranks fourth according to GLOBOCAN 2022. Its incidence in Asia, including Indonesia, continues to increase each year. Prostate cancer risk factors include both modifiable variables like blood pressure and body mass index (BMI) and non-modifiable variables like age and family history. This study aimed to determine the association between BMI and blood pressure with the incidence of prostate cancer. This study employed an analytical observational design using a retrospective hospital-based case-control approach. A total of 68 samples were collected, comprising 22 patients with benign prostatic hyperplasia (BPH) as the control group and 46 patients with prostate cancer as the case group. BMI and blood pressure data were collected from medical records and categorized based on the classifications from the WHO and PERHI (2019). The chi-square test was employed for the bivariate analysis with a significance level of p < 0.05. There was no significant associationfound between blood pressure and the incidence of prostate cancer (p = 0.304), while there was a significant association between BMI and the risk of prostate cancer (p = 0.023). The OR value of 0.581 with a 95% CI (0.205–1.645) indicated that blood pressure was not a statistically significant factor. These findings imply that hormonal alterations, persistent inflammation, and elevated insulin-like growth factor 1 (IGF-1) activity may raise the risk of prostate cancer in overweight individuals. In conclusion, BMI shows a significant association with prostate cancer incidence, whereas blood pressure does not demonstrate a significant association.
Interaction Between Agricultural Environmental Exposure and Inflammatory Biomarkers in Breast Cancer Risk Abdussalam, Arrizqi Hafidh; Kurniati, Yuni Prastyo; Romadhon, Yusuf Alam; Permatasari, Happy Kurnia; Sutrisna, Em
Medical Laboratory Technology Journal Vol. 11 No. 2 (2025): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i2.675

Abstract

Breast cancer remains the most common malignancy among women worldwide, and environmental exposures may contribute to breast carcinogenesis through inflammatory pathways such as NLR, PLR, and interferon-γ. This study aimed to examine the association between agricultural environmental exposure, represented by rice field area, and inflammatory biomarkers including the Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Interferon-γ in breast cancer. A case–control method was applied to 128 histopathologically confirmed samples consisting of 100 malignant (Invasive Carcinoma NST) and 28 benign (Fibroadenoma Mammae) breast tumors; hematologic indices were derived from preoperative blood tests, IFN-γ expression was analyzed immunohistochemically, and rice field proportions near participants’ residences were obtained from national statistics, with data analyzed using Chi-square and multivariate logistic regression. The results showed that agricultural exposure (rice field ≥60%) was not significantly associated with breast cancer (p = 0.703), whereas elevated NLR (OR = 4.89, p = 0.014), PLR (OR = 12.13, p = 0.017), and IFN-γ expression ≥20% (aOR = 23.94, p = 0.049) were significantly associated with malignancy. In conclusion, although agricultural land area was not a direct risk factor, inflammatory and immune biomarkers—particularly IFN-γ—served as strong predictors of breast cancer, indicating their potential utility in risk stratification for agrarian populations.
Analysis of Age Factor and Hemoglobin Profiles in The Incidence of Uterine Leiomyoma Paramarta, Nugrahani Putri Tyas; Kurniati, Yuni Prastyo
Jurnal Kesehatan Vol 16 No 3 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i3.5393

Abstract

Uterine leiomyoma is recognized as the most common benign tumor of the female reproductive system and remains a significant cause of gynecological morbidity worldwide. Its development has been closely associated with hormonal exposure, particularly estrogen and progesterone, and with reproductive age. Despite being frequently encountered in clinical practice, the role of other contributing factors, such as hemoglobin status, remains less clear. This study examined the relationships among age, hemoglobin concentration, and the incidence of uterine leiomyoma. An observational-analytic case-control design, using leiomyoma as cases and adenomyosis as controls, was conducted at PKU Muhammadiyah Hospital, Surakarta. A total of 246 participants were included, comprising 93 women with histopathologically confirmed leiomyoma and 153 women with adenomyosis as the control group. Data were obtained from hospital medical records, and statistical analyses were performed using Chi-square tests followed by logistic regression. The results demonstrated that being in the reproductive age group (≤50 years) significantly increased the likelihood of leiomyoma occurrence (OR=3.114, 95%CI: 1.141–8.500, p=0.021). In contrast, hemoglobin profiles did not show a significant association with leiomyoma incidence (OR=0.777, 95%CI: 0.428–1.441, p=0.407). Although anemia was frequently observed in both groups, it appeared more likely to be a clinical manifestation of abnormal uterine bleeding than a direct etiological factor.
STUDI KASUS-KONTROL: FAKTOR RISIKO ADENOMIOSIS PADA WANITA USIA REPRODUKSI DALAM KAITANNYA DENGAN TEKANAN DARAH DAN INDEKS MASSA TUBUH Gymnastiar, Ashar; Kurniati, Yuni Prastyo
Jurnal Riset Kesehatan Vol 14 No 2 (2025): NOVEMBER 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v14i2.13995

Abstract

Adenomyosis is a benign uterine condition characterized by the presence of endometrial tissue within the myometrium. This study aimed to analyze the association between blood pressure and body mass index with the incidence of adenomyosis. This study employed a case control design, in which the case group comprised patients diagnosed with adenomyosis, while the control group consisted of patients with uterine leiomyoma. The research was conducted at PKU Muhammadiyah Hospital Surakarta. A total of 221 medical record samples were collected using purposive sampling from 2020 to 2024, consisting of 130 cases of adenomyosis and 91 controls of uterine leiomyoma. Clinical variables including blood pressure, body mass index, age, parity, and residence were assessed. Data analysis was performed using Chi-Square tests. The results showed a significant association between blood pressure and the incidence of adenomyosis, with hypertensive women having a 2.7-fold higher risk of adenomyosis compared to normotensive women. In contrast, there was no significant association between body mass index and adenomyosis. In conclusion, the findings suggest that hypertension is a more prominent risk factor than obesity in the development of adenomyosis. Future studies involving to enhance preventive strategies and optimize clinical management.
The Role of Menarcheal Age and Parity in the Development of Uterine Leiomyoma Elvina Fawwaz Maharizdihar; Yuni Prastyo Kurniati
Journal of Health Sciences and Medical Development Vol. 4 No. 03 (2025): Forthcoming Issue - Journal of Health Sciences and Medical Development
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/hesmed.v4i03.1415

Abstract

Uterine leiomyoma is the most prevalent benign neoplasm of the female reproductive tract during the reproductive years; however, its precise etiology remains incompletely understood. Age at menarche and parity have been proposed as potential risk factors, although previous studies have reported inconsistent findings. This study aimed to evaluate the association between age at menarche and parity with the occurrence of uterine leiomyoma. This research employed a case-control design, in which uterine leiomyoma constituted the case group and adenomyosis served as the control group, conducted at PKU Muhammadiyah Hospital Surakarta. The study included 113 participants, comprising 73 cases of uterine leiomyoma and 40 cases of adenomyosis as controls, identified through histopathological records from 2023. Data were assessed using Chi-Square and logistic regression analyses. The findings revealed that most respondents experienced menarche at a normal age and were either primiparous or multiparous. Statistical testing demonstrated a significant association between age at menarche (p = 0.007; OR = 1.65, 95% CI = 1.414–1.939) and the incidence of uterine leiomyoma, whereas parity was not significantly associated (p = 0.384; OR = 1.509, 95% CI = 0.596–3.825). Future studies are recommended to include more balanced sample group proportions and additional risk factors to obtain a more comprehensive understanding of uterine leiomyoma etiology.
Co-Authors Abdussalam, Arrizqi Hafidh Alfajri, Asri Almansyah, Wanda Emdia Anika Candrasari Annisa, Celina Rizki Annisa, Valda Yulia Arismar, Fiqi Rahardian Aryati, Mandarini Dwi Putri Azizah Fatmawati Berliana, Sabna Ayu Sagita Bricareira Bara Presmasitha Celina Rizki Annisa Devi, Namira Aisya Dilla, Natasya Salsa Elvina Fawwaz Maharizdihar Em Sutrisna Faricha Kurnia Illahi Farma, Aufa Faza Fauzan Fathanita, Abiyya Firdausi, Nida Faradisa Futana, Ninda Pradani Gymnastiar, Ashar Handayani, Alya Nurkinasih Putri Happy Kurnia Permatasari Hilyati, Nor Ilmin Nafiah Islamuddin, Tri Kurnia Ahmad Khonsa, Khonsa Latifah, Lisanul Lestari, Nining Meliani, Reza Ika Muhammad Adnan N. Juni Triastuti Nabilah, Aisyah Nafiah, Ilmin Nugraheni, Fladea Eka Nur Mahmudah Nur Mahmudah Paramarta, Nugrahani Putri Tyas Parawansa, Karmila Indar Parawansa Povitasari, P Raharja, Supanji Ratih Pramuningtyas Retno Sintowati - Reza Ika Meliani Rosyita, Fadhilla Jihan Sahilah Ermawati Salsabila, Naura Siti Soekiswati Sri Wahyuni Supanji Raharja Tri Agustina Tri Kurnia Ahmad Islamuddin Tuanaya, Muhammad Rizqy Noer Valda Yulia Annisa Wibowo, Wahyu Aji Wirayudha, Yan Yunandar, Rio Yusuf Alam Romadhon Zahro, Ikhya' Izatus